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Fucidin Cream

Fucidin Cream

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  • ✔️ Targets bacterial skin infections including impetigo and infected eczema
  • ✔️ Contains fusidic acid 2%, effective against Staphylococcus aureus
  • ✔️ Visible improvement typically seen within 2 to 3 days of use
  • ✔️ Suitable for adults and children with localised skin infections
  • ✔️ Topical application means treatment acts directly at the infection site

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What Is Fucidin Cream and How Does It Treat Skin Infections?

 

Fucidin cream is a topical antibiotic treatment containing fusidic acid 2% as its active ingredient. It is used to treat bacterial skin infections caused by susceptible organisms, most commonly Staphylococcus aureus. Whether you're dealing with a patch of impetigo on your child's face or a small area of infected eczema, this cream targets the bacteria directly at the source. It's one of the most widely recognised topical antibiotics available in the UK, and you can find it alongside other creams and ointments at Cured Pharmacy.

Manufactured by LEO Pharma, Fucidin cream has been used clinically for decades. It is available in a 15g or 30g tube and is suitable for adults and children when used correctly. As with any antibiotic, it should only be used when genuinely needed — unnecessary use contributes to antibiotic resistance, which is a growing public health concern in the UK.

 

How Does Fucidin Cream Work Against Bacteria?

 

Fusidic acid, the active ingredient in Fucidin cream, works by interfering with bacterial protein synthesis. Specifically, it inhibits elongation factor G (EF-G), a protein essential for bacteria to produce the proteins they need to survive and replicate. Without this process, bacteria cannot multiply — and the infection gradually clears.

  • Fusidic acid penetrates the skin to reach the site of infection
  • It binds to EF-G, blocking the translocation step of protein synthesis
  • Bacteria are unable to replicate and begin to die off
  • The immune system clears remaining bacteria as the skin heals

It is particularly effective against Staphylococcus aureus, including some strains that are resistant to other antibiotics. However, it is not effective against all bacteria, so it's important to use it only for confirmed or strongly suspected bacterial infections.

 

Who Should Use Fucidin Cream and Is It Right for You?

 

Fucidin cream is suitable for adults and children with localised bacterial skin infections. It is commonly recommended for the following conditions:

  • Impetigo — a highly contagious superficial skin infection common in children
  • Infected eczema — where broken skin has become colonised by bacteria
  • Infected cuts, grazes, or minor wounds
  • Folliculitis — infection of the hair follicles

It is not suitable for fungal infections, viral infections such as cold sores, or large areas of broken skin without medical supervision. If you're unsure whether your skin condition is bacterial, speak to a pharmacist or GP before starting treatment. You might also want to explore our skin care range for complementary products to support your skin health.

 

How Does Fucidin Cream Compare to Other Topical Antibiotics?

 

Feature Fucidin Cream Mupirocin (Bactroban)
Active ingredient Fusidic acid 2% Mupirocin 2%
Primary use Skin infections, infected eczema Impetigo, nasal decolonisation
Formulation Cream (water-based) Ointment or nasal ointment
UK availability Prescription / pharmacy Prescription only

 

How Should You Store Fucidin Cream and Is It Safe Long-Term?

 

Store fucidin cream below 25°C, away from direct heat and sunlight. Keep the tube tightly closed when not in use, and always store it out of reach of children. Do not use the cream after the expiry date printed on the packaging.

Long-term or repeated use of any topical antibiotic carries a risk of promoting antibiotic resistance and may cause sensitisation of the skin. For this reason, treatment courses are typically limited to 5–7 days. If your symptoms have not improved after this time, consult your GP rather than continuing to apply the cream independently.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Fucidin Cream specifications
Treatment category Topical antibiotic
Mechanism of action Inhibits bacterial protein synthesis via EF-G inhibition
Effective against Staphylococcus aureus and other susceptible bacteria
Suitable for Adults and children (under medical supervision for infants)
Active ingredient Fusidic acid 2%
Pack sizes 15g, 30g
Strengths 2% w/w
UK classification Pharmacy (P) / Prescription Only Medicine (POM) depending on indication
Drug class Fusidane antibiotic
Preparation Cream
Route of administration Topical (cutaneous)

Specifications of Fucidin Cream

 

What Is Fucidin Cream and What Is It Used For?

 

Fucidin cream is a topical antibiotic medicine containing fusidic acid 2% w/w. It is used to treat bacterial infections of the skin caused by susceptible organisms, particularly Staphylococcus aureus. Common conditions it is prescribed or recommended for include impetigo, infected eczema, infected cuts and grazes, and folliculitis. It works locally on the skin rather than being absorbed into the bloodstream in significant amounts, which makes it a targeted option for superficial infections.

 

What Do You Need to Know Before Using Fucidin Cream?

 

Before applying fucidin cream, read the following carefully. There are situations where this medicine should not be used or should be used with caution.

Do not use Fucidin cream if you:

  • Are allergic to fusidic acid, sodium fusidate, or any other ingredient in the cream
  • Have a fungal or viral skin infection — this cream will not treat these
  • Need to apply it to large areas of broken or damaged skin without medical advice
  • Are applying it near the eyes without specific medical guidance

Use with caution and speak to a pharmacist or GP if you:

  • Are pregnant or breastfeeding
  • Are treating a young infant or newborn
  • Have previously had a skin reaction to any topical antibiotic
  • Have been using the cream for longer than 7 days without improvement

Drug interactions:

  • Topical fusidic acid has no significant known interactions with other medicines when used as directed on the skin
  • If you are also taking systemic antibiotics, inform your prescriber to avoid overlapping antibiotic coverage

 

How Should You Use Fucidin Cream Correctly?

 

Always use Fucidin cream exactly as directed by your pharmacist or as described in the patient information leaflet. Do not apply more than recommended, and do not use it for longer than advised.

  1. Wash your hands thoroughly before and after application (unless treating the hands themselves)
  2. Clean the affected area gently with mild soap and water, then pat dry
  3. Apply a small amount of cream to the infected area and spread gently
  4. Do not cover with an airtight dressing unless advised by a healthcare professional
  5. Apply at regular intervals as directed — typically two to three times daily
  6. Complete the full course of treatment, even if the skin looks better before it ends
Indication Age Group Dose Frequency
Impetigo / skin infection Adults Small amount to affected area 2–3 times daily for 5–7 days
Infected eczema Adults & children Small amount to affected area 2–3 times daily for up to 7 days
Minor wound infection Adults & children Small amount to affected area 2–3 times daily for 5 days

If you are looking for additional support for wound care or minor injuries, our first aid range includes a variety of products to help manage minor skin injuries safely.

 

What Are the Possible Side Effects of Fucidin Cream?

 

Like all medicines, Fucidin cream can cause side effects, although not everyone experiences them. Most side effects are mild and affect the skin at the site of application.

Common side effects:

  • Mild burning or stinging sensation on application
  • Redness or irritation at the application site
  • Itching or skin discomfort

Less common side effects:

  • Contact dermatitis — an allergic skin reaction causing rash or blistering
  • Eczematous reactions — worsening of existing eczema
  • Skin sensitisation with prolonged use

Stop using the cream and seek medical advice if you develop signs of a severe allergic reaction, such as widespread rash, swelling, or difficulty breathing. These reactions are rare but require prompt attention.

 

How Should You Store Fucidin Cream?

 

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Keep the tube tightly closed after each use
  • Store out of the sight and reach of children
  • Do not use after the expiry date printed on the tube or carton
  • Do not dispose of medicines via wastewater or household waste — return unused medicines to your pharmacy

If you are managing a skin condition alongside other health concerns, you may also find our athletes foot and fungal infections range helpful — though remember that Fucidin cream is not suitable for fungal conditions and a different treatment would be needed.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Fucidin cream online in the UK?

You can buy Fucidin cream online from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available subject to a short suitability assessment completed at checkout. Browse our full range of creams and ointments for related topical treatments.

How does Fucidin cream work on a skin infection?

Fucidin cream contains fusidic acid, which inhibits bacterial protein synthesis by blocking elongation factor G (EF-G). This stops bacteria from replicating, allowing your immune system and the skin's natural healing process to clear the infection. It is particularly effective against Staphylococcus aureus, the most common cause of superficial skin infections.

How do I apply Fucidin cream step by step?

Wash your hands, then clean and dry the affected area gently. Apply a small amount of cream directly to the infected skin and rub in lightly. Wash your hands again after application unless the hands themselves are being treated.

How long does Fucidin cream take to work?

Most people notice visible improvement within 2 to 3 days of starting treatment. You should complete the full course — usually 5 to 7 days — even if the skin appears to have cleared up sooner. Stopping early can allow bacteria to return and may contribute to antibiotic resistance.

What is the correct dose of Fucidin cream for adults?

For adults, apply a small amount of Fucidin cream to the affected area two to three times daily. Treatment should not normally exceed 7 days without medical review. Always follow the instructions provided by your pharmacist or the patient information leaflet.

Can I use Fucidin cream on my child?

Fucidin cream can be used in children, including for conditions like impetigo, but should be used under the guidance of a pharmacist or GP, especially in infants. The dose and frequency are generally the same as for adults — a small amount applied two to three times daily. Always seek professional advice before treating young children with any antibiotic.

What are the side effects of Fucidin cream?

Common side effects include mild stinging, redness, or itching at the application site. Less commonly, contact dermatitis or skin sensitisation may occur, particularly with prolonged use. If you develop a widespread rash, swelling, or any sign of a severe allergic reaction, stop using the cream and seek medical advice immediately.

How do I manage side effects of Fucidin cream?

Mild irritation usually settles on its own as your skin adjusts to the treatment. If stinging or redness is bothersome, try applying the cream after gently moisturising the surrounding skin. If side effects persist or worsen, stop using the cream and speak to your pharmacist or GP.

Who is eligible to use Fucidin cream?

Fucidin cream is suitable for adults and children with localised bacterial skin infections caused by susceptible organisms. It is not suitable for people with known hypersensitivity to fusidic acid, or for treating fungal or viral infections. Pregnant or breastfeeding women should consult a GP before use.

What happens if I miss a dose of Fucidin cream?

If you forget to apply Fucidin cream at your usual time, apply it as soon as you remember. If it is nearly time for your next application, skip the missed dose and continue as normal. Do not apply a double amount to make up for a missed application.

What is the difference between Fucidin cream and Fucidin ointment?

Fucidin cream is water-based and absorbs more readily into the skin, making it better suited to moist, weeping, or inflamed areas. Fucidin ointment has a greasier, occlusive base that may be more appropriate for dry or scaly skin. Both contain fusidic acid 2% as the active ingredient.

Can I use Fucidin cream during pregnancy or breastfeeding?

Fucidin cream should only be used during pregnancy or breastfeeding if a doctor considers it necessary. While topical absorption is minimal, it is always best to seek professional advice before using any medicine during pregnancy. Avoid applying the cream to the breast area if breastfeeding.

How long can you use Fucidin cream for?

Treatment with Fucidin cream should not normally exceed 7 days. Prolonged use increases the risk of antibiotic resistance and skin sensitisation. If your infection has not improved after a week, consult your GP rather than continuing to self-treat.

What are the alternatives to Fucidin cream?

Alternatives to Fucidin cream include mupirocin (Bactroban), which is a prescription-only topical antibiotic also used for impetigo. For mild infections, antiseptic creams may be considered, though they are less targeted. Your pharmacist can advise on the most appropriate option for your specific condition. You can also explore our skin care range for supportive products.

What does the latest research say about fusidic acid resistance?

Antibiotic resistance to fusidic acid is a recognised and growing concern, particularly with repeated or prolonged use of topical formulations. UK guidance recommends limiting treatment courses to 5–7 days and avoiding use as a preventative measure. Using fucidin cream only when clinically indicated helps preserve its effectiveness for future patients.

How Should You Use Fucidin Cream?

Always use Fucidin cream exactly as directed by your pharmacist or GP. Before applying, make sure the affected area is clean and dry. Wash your hands before and after each application, unless you are treating the hands themselves.

Avoid getting the cream in your eyes, mouth, or nose. If accidental contact occurs, rinse thoroughly with water. Do not apply to large areas of broken skin without medical advice.

What Is the Correct Dose of Fucidin Cream?

The dose of Fucidin cream depends on the condition being treated and the age of the patient. As a general rule, apply a small amount to the affected area two to three times daily. Do not apply more than directed — using extra cream will not speed up recovery and may increase the risk of side effects.

When Is the Best Time to Use Fucidin Cream?

There is no single "best" time of day to apply Fucidin cream, but spacing your applications evenly throughout the day helps maintain a consistent level of the medicine on the skin. For example, if applying three times daily, you might choose morning, midday, and evening. Try to apply at roughly the same times each day to build a routine and reduce the chance of missing a dose.

Applying the cream after washing the affected area — such as after a shower or bath — can be particularly effective, as the skin is clean and the cream can be absorbed without interference from dirt or other products.

How Long Can You Use Fucidin Cream For?

Treatment with Fucidin cream should not normally exceed 7 days. Most bacterial skin infections respond well within this timeframe. Continuing beyond 7 days without medical review is not recommended, as prolonged use can increase the risk of antibiotic resistance and skin sensitisation.

If your symptoms have not improved after 5 to 7 days of treatment, or if they worsen at any point, stop using the cream and consult your GP. Do not restart a course of Fucidin cream without seeking professional advice first.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Fucidin Cream?

Most people who use Fucidin cream do not experience significant side effects. When they do occur, they are usually mild and limited to the area of skin where the cream has been applied. These reactions often settle on their own as treatment continues.

  • Mild burning or stinging sensation immediately after application
  • Redness or erythema at the application site
  • Itching or skin discomfort
  • Dry skin around the treated area

What Are the Less Common Side Effects of Fucidin Cream?

Less commonly, some people may experience more noticeable skin reactions. These are more likely to occur with prolonged use or in individuals with sensitive skin. If any of the following develop, stop using the cream and speak to your pharmacist or GP.

  • Contact dermatitis — an allergic skin reaction causing rash, blistering, or swelling
  • Eczematous reactions — a worsening of pre-existing eczema
  • Skin sensitisation — increased sensitivity to the cream with repeated use
  • Localised oedema (swelling) at the application site

What Are the Serious Side Effects of Fucidin Cream?

Serious side effects from topical Fucidin cream are rare, but they can occur. A severe allergic reaction (anaphylaxis) is uncommon but requires immediate medical attention. Signs to watch for include widespread skin rash or hives, swelling of the face, lips, or throat, difficulty breathing, or a sudden drop in blood pressure causing dizziness or collapse.

If you experience any of these symptoms after applying Fucidin cream, stop using it immediately and call 999 or go to your nearest A&E department. Do not wait to see if symptoms improve on their own.

What Should You Do If You Experience Side Effects?

For mild side effects such as stinging or redness, you may find that symptoms ease after the first few applications as your skin adjusts. Avoid applying the cream to broken or raw skin beyond the infected area, and do not use more than the recommended amount. If irritation persists beyond 2 to 3 days, seek pharmacist advice.

You can report suspected side effects of any medicine in the UK through the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk. This helps regulators monitor the safety of medicines in real-world use.

Can Fucidin Cream Interact With Other Medicines?

When used topically as directed, Fucidin cream has no significant known interactions with other medicines. The amount of fusidic acid absorbed through the skin is minimal under normal conditions, so systemic drug interactions are unlikely. However, if you are also taking oral or intravenous antibiotics, inform your prescriber so they can ensure your treatment plan is appropriate and avoid unnecessary overlap.

Always tell your pharmacist about all medicines you are currently taking, including over-the-counter products and herbal remedies, before starting any new treatment.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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