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Orlos (Orlistat) 60mg Weight Loss Aid

Orlos (Orlistat) 60mg Weight Loss Aid

  • 1. Ozempic®️-equivalent therapy now available for weight management
  • 2. Average weight loss of 17%, with 1 in 3 patients achieving over 20%
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  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

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Orlos (Orlistat) 60mg Weight Loss Aid is an over-the-counter medication designed to support weight loss in adults who are overweight. It works by blocking the absorption of dietary fat in the body, helping to reduce overall calorie intake and support healthy weight management. Orlistat, the active ingredient, targets fat in the digestive system, preventing it from being stored and aiding in effective weight reduction.

Taken orally as a capsule with each main meal containing fat, Orlos is most effective when used alongside a balanced, low-fat diet and regular physical activity. It offers a practical solution for those looking to manage their weight and improve long-term health outcomes.

Always follow the dosage and usage instructions provided with the product or as directed by a healthcare professional to ensure safe and effective use.

Directions for Use for Orlos 60mg Capsules

It’s very important you know how to take Orlos. When taking Orlos correctly, it makes a big difference to the result and also how comfortable you will feel whilst being on the medication. Since it works directly in your digestive system, timing and diet matter a lot.

How to take Orlos

You should take Orlos three times a day, with each main meal that contains fat. Take one 60mg capsule whole.


How long should I take Orlos?

You should use Orlos as part of a longer-term weight loss plan, usually for up to 12 weeks initially. But treatment should not go longer than 6 months.

Possible Side Effects of Orlos 60mg

As with all medications, Orlos can have side effects, although not everybody gets them. As Orlos acts by preventing fat from being absorbed in your digestive system, symptoms are mainly caused by your body adjusting to the way in which it receives undigested fat.

Common side effects

These types of effect are more common but are usually mild.

  • Oily or fatty stools       
  • Gas with oily spotting
  • Frequent bowel movements
  • Stomach pain.
  • Mild diarrhoea

Less common side effects

  • Headache
  • Tiredness       
  • Irregular periods
  • Tooth discomfort

Rare but serious side effects

  • Signs of an allergic reaction 
  • Severe abdominal pain
  • Yellowing of the skin or eyes, dark urine
  • Blood in urine
  • kidney pain

If any of the side effects gets serious, or if you notice any side effects not listed in this LEAFLET, please tell your pharmacist.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2088658
Muzammil Peerally

Authored by:

Muzammil Peerally

Superintendent Pharmacist

GPhC Number: 2232689
Tarun Kumar

Reviewed by:

Tarun Kumar

Clinical Leads

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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Active Ingredient Tirzepatide Semaglutide Liraglutide
Mechanism of Action GLP-1 and GIP receptor agonist GLP-1 receptor agonist GLP-1 receptor agonist
Administration Weekly injection Weekly injection Daily injection
Dosage Varies by patient, typically starting low Varies, typically starting at 0.25 mg Varies, starting at 0.6 mg
Effect on Appetite Significantly reduces appetite and cravings Reduces appetite and increases satiety Reduces appetite and increases satiety
Average Weight Loss Up to 20% body weight reduction Up to 15% body weight reduction Significant weight reduction
Side Effects Nausea, vomiting, diarrhoea, constipation Nausea, vomiting, diarrhoea, constipation Nausea, diarrhoea, constipation, hypoglycemia
Approval FDA-approved for weight loss FDA-approved for weight loss FDA-approved for weight loss
Suitable For Adults with BMI ≥30 or ≥27 with comorbidities Adults with BMI ≥30 or ≥27 with comorbidities Adults with BMI ≥30 or ≥27 with comorbidities