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Acidex Advance Oral Suspension Aniseed

Acidex Advance Oral Suspension Aniseed

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  • ✔️ Forms a protective alginate raft to block acid reflux
  • ✔️ Relieves heartburn and indigestion after meals
  • ✔️ Pleasant aniseed flavour for easy, comfortable dosing
  • ✔️ Suitable for adults and children aged 12 and over
  • ✔️ Contains antacid action to neutralise excess stomach acid

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What Is Acidex Advance Oral Suspension Aniseed?

 

If you've ever felt that uncomfortable burning sensation creeping up your chest after a meal, you'll know how disruptive heartburn can be. Acidex advance oral suspension is an over-the-counter alginate-based antacid liquid designed to relieve exactly that — heartburn, acid reflux, and indigestion. Available in a pleasant aniseed flavour, it's a practical choice for adults and children aged 12 and over who want fast, targeted relief without a prescription. You can browse our full range of indigestion treatments if you'd like to compare your options.

Each 10 ml dose contains three active ingredients: sodium alginate 500 mg, sodium bicarbonate 267 mg, and calcium carbonate 160 mg. Together, these work to both neutralise stomach acid and create a physical barrier against reflux. It's a well-established formulation that has been used in the UK for many years, and it's classified as a General Sale List (GSL) medicine by the MHRA.

 

How Does Acidex Advance Oral Suspension Work?

 

The mechanism behind Acidex Advance is genuinely clever. Rather than simply neutralising acid throughout the stomach, it targets the root cause of reflux — the movement of acidic stomach contents back up into the oesophagus. Here's how it works step by step:

  • Sodium alginate reacts with stomach acid to form a thick, viscous gel.
  • This gel floats on top of the stomach contents, creating a physical "raft" that acts as a barrier.
  • Sodium bicarbonate generates carbon dioxide, which helps the raft float effectively.
  • Calcium carbonate provides additional antacid action, helping to neutralise excess acid in the stomach.
  • The raft is preferentially refluxed instead of acidic stomach contents, protecting the oesophageal lining.

This raft-forming mechanism is what distinguishes alginate-based products from simple antacids. It provides both symptomatic relief and a degree of physical protection — particularly useful after meals, when reflux is most likely to occur.

 

Who Should Use Acidex Advance Oral Suspension?

 

Acidex Advance is suitable for a broad range of people experiencing mild to moderate acid-related symptoms. It's particularly well-suited to those who find symptoms worse after eating or when lying down. That said, it's not appropriate for everyone — always read the label carefully.

  • Adults aged 18 and over experiencing heartburn or acid reflux.
  • Adolescents aged 12–17 under appropriate supervision.
  • Pregnant women suffering from heartburn (seek pharmacist advice first).
  • People who prefer a liquid formulation over tablets or capsules.

It is not suitable for children under 12 years of age without medical advice. If you're also managing symptoms like bloating or cramping alongside your reflux, it may be worth exploring our IBS and cramps range for complementary options.

 

How Does Acidex Advance Compare to Other Heartburn Suspensions?

 

Feature Acidex Advance Oral Suspension Gaviscon Advance Liquid
Active ingredients Sodium alginate, sodium bicarbonate, calcium carbonate Sodium alginate, potassium bicarbonate
Mechanism Raft-forming alginate antacid Raft-forming alginate (no antacid component)
Suitable for pregnancy Seek pharmacist advice Generally considered suitable — seek advice
Sodium content Moderate — caution on low-sodium diets Higher sodium — caution on low-sodium diets

 

How Should You Store Acidex Advance Oral Suspension?

 

Proper storage keeps the suspension effective and safe to use. Store Acidex advance oral suspension below 25°C in a cool, dry place away from direct sunlight. Do not freeze the product — freezing can alter the consistency of the suspension and affect how well it works. Always keep the bottle tightly closed when not in use.

Once opened, check the expiry date on the bottle and do not use it beyond that date. Keep it out of the reach and sight of children at all times. If you notice any changes in colour, smell, or texture, do not use the product and dispose of it safely.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Acidex Advance Oral Suspension Aniseed specifications
Treatment category Heartburn & Indigestion
Mechanism of action Alginate raft-forming antacid
Effective for Heartburn, acid reflux, indigestion
Suitable for Adults and children aged 12 and over
Active ingredients Sodium alginate 500 mg, Sodium bicarbonate 267 mg, Calcium carbonate 160 mg per 10 ml
Pack size 500 ml
UK classification General Sale List (GSL)
Drug class Alginate antacid
Preparation Oral suspension
Route of administration Oral

Specifications of Acidex Advance Oral Suspension Aniseed

 

What Is Acidex Advance Oral Suspension and What Is It Used For?

 

Acidex Advance Oral Suspension Aniseed is an alginate-based antacid medicine used to relieve the symptoms of heartburn, gastro-oesophageal reflux, and indigestion. It works by forming a protective raft on top of stomach contents, preventing acid from rising into the oesophagus. It is available without a prescription and is classified as a General Sale List (GSL) medicine in the UK. The aniseed flavour makes it a more palatable option for those who find plain antacid suspensions unpleasant.

Heartburn is extremely common in the UK — the NHS notes that most people experience it at some point in their lives. Symptoms include a burning sensation in the chest, an unpleasant sour taste in the mouth, and discomfort after eating. Acidex Advance oral suspension is designed to address these symptoms quickly and effectively after meals or at bedtime.

 

What Do You Need to Know Before Using Acidex Advance Oral Suspension?

 

Before using this medicine, it's important to be aware of certain conditions and circumstances where it may not be appropriate. Always read the patient information leaflet supplied with the product.

Do not use Acidex Advance if you:

  • Are allergic to any of the active or excipient ingredients.
  • Have been told to follow a low-sodium or sodium-restricted diet (the product contains sodium).
  • Have severely impaired kidney function without first consulting your GP.
  • Are under 12 years of age (not recommended without medical supervision).

Speak to your pharmacist or GP before use if you:

  • Are pregnant or breastfeeding.
  • Have a history of kidney stones (the calcium carbonate content may be relevant).
  • Are on a calcium-restricted diet.
  • Have any other significant medical condition.

Drug interactions to be aware of:

  • Antacids can reduce the absorption of certain medicines, including some antibiotics (e.g. tetracyclines), bisphosphonates, and iron supplements.
  • Leave a gap of at least 2 hours between taking Acidex Advance and any other medicines.
  • If you are taking prescribed medicines regularly, speak to your pharmacist before starting this product.

 

How Should You Use Acidex Advance Oral Suspension?

 

Always use this medicine exactly as described on the label or as directed by your pharmacist. Do not exceed the recommended dose.

  1. Shake the bottle well before each use.
  2. Measure the correct dose using the measuring cup provided.
  3. Take the suspension after meals and at bedtime.
  4. Swallow the dose directly — do not dilute with water.
  5. Do not take more than four doses in any 24-hour period.
Indication Age Group Dose Frequency
Heartburn / acid reflux Adults & children 12+ 10–20 ml After meals and at bedtime (max 4 times daily)
Indigestion Adults & children 12+ 10–20 ml After meals and at bedtime (max 4 times daily)
Children under 12 Under 12 Not recommended Seek medical advice

If you're also experiencing nausea alongside your reflux symptoms, our sickness and nausea range may offer additional support.

 

What Are the Possible Side Effects of Acidex Advance Oral Suspension?

 

Like all medicines, Acidex Advance can cause side effects, although not everyone experiences them. Most side effects are mild and resolve on their own.

Common side effects:

  • Bloating or flatulence (due to carbon dioxide released by sodium bicarbonate).
  • Nausea.
  • A mild laxative effect in some individuals.

Less common side effects:

  • Constipation (particularly with higher doses or prolonged use).
  • Raised blood sodium levels with excessive long-term use — relevant for those on sodium-restricted diets.
  • Allergic reactions (rare) — symptoms may include rash, itching, or swelling.

Stop using the product and seek medical advice immediately if you experience signs of a serious allergic reaction, such as difficulty breathing, swelling of the face or throat, or a severe skin reaction.

 

How Should You Store Acidex Advance Oral Suspension?

 

  • Store below 25°C in a cool, dry place.
  • Do not freeze.
  • Keep the bottle tightly closed after use.
  • Keep out of the reach and sight of children.
  • Do not use after the expiry date printed on the bottle.
  • Do not dispose of medicines via wastewater or household waste — return unused medicines to your pharmacy.

If you're managing a range of digestive health concerns, it's worth exploring our pain relief range for any associated discomfort you may be experiencing alongside your reflux symptoms.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Acidex Advance Oral Suspension Aniseed online in the UK?

You can buy Acidex Advance Oral Suspension Aniseed directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £5.59. It's available without a prescription as a General Sale List medicine. Simply add it to your basket and it will be dispatched to your door.

How does Acidex Advance Oral Suspension work in the body?

Acidex Advance works through a raft-forming mechanism. Sodium alginate reacts with stomach acid to create a thick gel that floats on top of stomach contents, acting as a physical barrier against acid reflux. Sodium bicarbonate and calcium carbonate provide additional antacid action to neutralise excess stomach acid.

How do I use Acidex Advance Oral Suspension step by step?

Shake the bottle well before each use, then measure 10–20 ml using the measuring cup provided. Take the dose after meals and at bedtime — swallow it directly without diluting. Do not take more than four doses in any 24-hour period.

What is the correct dose of Acidex Advance for adults?

The recommended adult dose is 10–20 ml taken after meals and at bedtime, up to a maximum of four times daily. Always follow the directions on the product label or as advised by your pharmacist. Do not exceed the stated dose.

What is the best time to take Acidex Advance Oral Suspension?

The best time to take Acidex Advance is after meals and at bedtime, as this is when acid reflux and heartburn are most likely to occur. Taking it after eating allows the alginate raft to form on top of recently ingested food, providing the most effective barrier. The bedtime dose is particularly helpful for those who experience night-time reflux symptoms.

What are the side effects of Acidex Advance Oral Suspension?

Side effects are uncommon but may include bloating, flatulence, or mild nausea — largely due to the carbon dioxide released by sodium bicarbonate. Less commonly, some people may experience constipation with prolonged use. If you notice any unusual or persistent symptoms, stop use and speak to your pharmacist or GP.

How do I manage side effects of Acidex Advance Oral Suspension?

Most side effects, such as bloating or mild nausea, are temporary and tend to resolve without any specific treatment. Reducing your dose slightly may help if bloating is bothersome. If side effects persist or are severe, stop using the product and consult your pharmacist or GP for further guidance.

Who is eligible to use Acidex Advance Oral Suspension?

Acidex Advance is suitable for adults and young people aged 12 and over who experience heartburn, acid reflux, or indigestion. It is not recommended for children under 12 without medical advice. People on sodium-restricted diets or with significant kidney problems should speak to their GP or pharmacist before use.

Can I use Acidex Advance Oral Suspension during pregnancy?

Heartburn is very common during pregnancy, and alginate-based antacids are often considered among the first-line options. However, you should always speak to your pharmacist or midwife before taking any medicine during pregnancy, including Acidex Advance. They can advise on the most appropriate treatment based on your individual circumstances.

What happens if I miss a dose of Acidex Advance Oral Suspension?

If you miss a dose, simply take it as soon as you remember — unless it is nearly time for your next scheduled dose. In that case, skip the missed dose and continue as normal. Never take a double dose to make up for one you have missed.

How long can you use Acidex Advance Oral Suspension for?

Acidex Advance is intended for short-term relief of heartburn and indigestion symptoms. If your symptoms persist for more than 7 days, worsen, or are accompanied by other symptoms such as difficulty swallowing or unexplained weight loss, you should consult your GP. Prolonged or frequent heartburn may require further investigation and a different treatment approach.

What are the alternatives to Acidex Advance Oral Suspension?

Common alternatives include other alginate-based products such as Gaviscon Advance Liquid, or simple antacids containing calcium carbonate or magnesium trisilicate. For more persistent symptoms, a GP may recommend a proton pump inhibitor (PPI) such as omeprazole. You can explore our full indigestion treatments range to compare available options.

Can Acidex Advance Oral Suspension interact with other medicines?

Yes — antacid-containing products like Acidex Advance can reduce the absorption of certain medicines, including tetracycline antibiotics, bisphosphonates, and iron supplements. It is recommended to leave a gap of at least 2 hours between taking Acidex Advance and any other medicines. Always inform your pharmacist of all medicines you are currently taking.

Is Acidex Advance Oral Suspension suitable for people on a low-sodium diet?

Acidex Advance contains sodium as part of its active ingredients, so it may not be suitable for people who have been advised to follow a strict low-sodium or sodium-restricted diet. If you have heart failure, high blood pressure, or kidney disease and are on a sodium-restricted diet, speak to your GP or pharmacist before using this product. They can recommend a more appropriate alternative if needed.

What are the latest studies on alginate antacids like Acidex Advance?

Alginate-based antacids have been well-studied over several decades and are recognised by the NHS as an effective first-line treatment for mild to moderate heartburn and gastro-oesophageal reflux. Research consistently supports the raft-forming mechanism as an effective way to reduce acid exposure in the oesophagus. If you'd like to read more about managing digestive health, our IBS and cramps section contains further useful information.

How Should You Use Acidex Advance Oral Suspension?

Using Acidex Advance correctly makes a real difference to how well it works. Always shake the bottle thoroughly before each use to ensure the suspension is evenly mixed, as the active ingredients can settle at the bottom between doses.

What Is the Correct Dose of Acidex Advance Oral Suspension?

The dose varies depending on age. Always follow the label instructions and do not exceed the maximum daily dose. Taking more than recommended will not improve symptom relief and may increase the risk of side effects.

When Is the Best Time to Use Acidex Advance Oral Suspension?

Timing matters with this product. The most effective time to take Acidex Advance is after meals and at bedtime — this is when stomach acid production is highest and reflux is most likely to occur. Taking it after eating means the alginate raft forms on top of food in the stomach, providing a more effective barrier against acid rising into the oesophagus. The bedtime dose is especially useful for people who experience symptoms when lying down at night.

How Long Can You Use Acidex Advance Oral Suspension For?

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What Are the Most Common Side Effects of Acidex Advance Oral Suspension?

Most people tolerate Acidex Advance well, and side effects are generally uncommon. When they do occur, they tend to be mild and short-lived. The most frequently reported side effects are related to the sodium bicarbonate component, which releases carbon dioxide in the stomach.

  • Bloating or a feeling of fullness.
  • Flatulence (wind).
  • Mild nausea.

What Are the Less Common Side Effects of Acidex Advance Oral Suspension?

Less commonly, some people may experience the following, particularly with higher doses or prolonged use. If any of these persist or become troublesome, speak to your pharmacist.

  • Constipation — the calcium carbonate component can have a mild constipating effect in some individuals.
  • Raised blood sodium levels — relevant mainly for those on sodium-restricted diets or with kidney problems who use the product long-term.
  • Diarrhoea — occasionally reported, though uncommon.

What Are the Serious Side Effects of Acidex Advance Oral Suspension?

Serious side effects are rare but can occur. Allergic reactions to any of the ingredients, while uncommon, are possible. You should stop using the product immediately and seek urgent medical attention if you experience any of the following:

  • Swelling of the face, lips, tongue, or throat.
  • Difficulty breathing or swallowing.
  • Severe skin rash, hives, or itching.
  • Chest tightness or a sudden drop in blood pressure (feeling faint).

What Should You Do If You Experience Side Effects of Acidex Advance?

For mild side effects such as bloating or nausea, reducing your dose slightly may help. These effects often resolve on their own without any specific treatment. If side effects are persistent, worsening, or causing significant discomfort, stop using the product and consult your pharmacist or GP. You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Acidex Advance Oral Suspension Interact With Other Medicines?

Yes — because Acidex Advance contains antacid components, it can affect the absorption of other medicines taken at the same time. This is particularly relevant for tetracycline antibiotics, bisphosphonates (used for bone conditions), iron supplements, and some antifungal medicines. To minimise the risk of interactions, always leave a gap of at least 2 hours between taking Acidex Advance and any other medicines. If you are taking prescribed medicines regularly, speak to your pharmacist before starting this product.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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