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Acidex Advance Oral Suspension Peppermint- 500ml

Acidex Advance Oral Suspension Peppermint- 500ml

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  • ✔️ Forms a protective alginate raft to block acid reflux
  • ✔️ Neutralises excess stomach acid for fast heartburn relief
  • ✔️ Dual-action formula targets both reflux and indigestion
  • ✔️ Suitable for adults and young people aged 12 and over
  • ✔️ Refreshing peppermint flavour in a generous 500ml bottle

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What Is Acidex Advance Oral Suspension and How Does It Help Heartburn?

 

If you've ever felt that burning sensation creeping up your chest after a meal, you'll know how disruptive heartburn can be. Acidex advance oral suspension is an alginate-antacid preparation designed to provide fast, effective relief from heartburn, acid reflux, and indigestion. Available in a refreshing peppermint flavour, this 500ml suspension is a practical, easy-to-take option for adults and children aged 12 and over. You can browse our full range of indigestion treatments if you'd like to compare your options before deciding.

Heartburn occurs when stomach acid flows back up into the oesophagus — a process known as gastro-oesophageal reflux. It's a very common condition in the UK, affecting millions of people regularly. Acidex Advance is classified as a general sale medicine, meaning you can purchase it without a prescription, making it a convenient first-line option for managing mild to moderate reflux symptoms.

 

How Does Acidex Advance Oral Suspension Work?

 

The mechanism behind Acidex Advance is a dual-action approach — it both neutralises acid and creates a physical barrier to stop it rising. Here's how it works step by step:

  • Alginate raft formation: Sodium alginate reacts with stomach acid to form a thick, gel-like raft that floats on top of the stomach contents, acting as a physical barrier against reflux.
  • Acid neutralisation: Sodium bicarbonate and calcium carbonate work together to neutralise excess gastric acid, reducing the pH in the stomach and easing the burning sensation.
  • Symptom relief: The combined effect means acid is less likely to escape into the oesophagus, and any that does is less corrosive — providing relief from the discomfort of heartburn and regurgitation.
  • Rapid onset: The liquid suspension format means the active ingredients are quickly distributed across the stomach lining, generally offering faster relief than tablet-based alternatives.

 

Who Should Use Acidex Advance Oral Suspension?

 

This suspension is suitable for a wide range of people experiencing common digestive complaints. It's particularly useful if you prefer a liquid medicine over tablets, or if you find swallowing tablets difficult. That said, it's not appropriate for everyone — always read the label carefully.

Acidex Advance oral suspension is well suited for:

  • Adults and adolescents aged 12 and over experiencing heartburn or acid reflux
  • People with indigestion symptoms following meals or at night
  • Those who prefer a liquid antacid over chewable tablets or capsules
  • Individuals looking for a peppermint-flavoured option that's pleasant to take

 

How Does Acidex Advance Compare to Other Antacid Suspensions?

 

Feature Acidex Advance Oral Suspension Standard Antacid Liquid (e.g. Gaviscon Advance)
Mechanism Alginate raft + antacid neutralisation Alginate raft formation
Active ingredients Sodium alginate, sodium bicarbonate, calcium carbonate Sodium alginate, potassium bicarbonate
Flavour Peppermint Peppermint or aniseed
Pack size 500ml 150ml or 300ml
Suitable for 12+ Yes Yes (varies by product)

 

Is Acidex Advance Oral Suspension Suitable for Long-Term Use?

 

Acidex advance oral suspension is intended for short-term relief of heartburn and indigestion symptoms. If you find yourself relying on it daily for more than a week, it's worth speaking to your GP — persistent reflux can sometimes indicate an underlying condition that needs further investigation. People on sodium-restricted diets should also take note, as this product contains sodium, which may be a consideration if you're managing conditions such as hypertension or kidney disease.

If you're also managing other digestive concerns alongside heartburn, you might find it helpful to explore our IBS and cramps treatments for a broader approach to gut health. Store the suspension below 25°C and keep it out of reach of children.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Acidex Advance Oral Suspension Peppermint 500ml specifications
Treatment category Antacid / Alginate reflux suppressant
Mechanism of action Alginate raft formation and gastric acid neutralisation
Effective for Heartburn, acid reflux, indigestion
Suitable for Adults and children aged 12 and over
Active ingredients Sodium alginate, Sodium bicarbonate, Calcium carbonate
Pack size 500ml
UK classification General Sale Medicine (GSL)
Drug class Alginate-antacid combination
Preparation Oral suspension
Route of administration Oral

Specifications of Acidex Advance Oral Suspension Peppermint 500ml

 

What Is Acidex Advance Oral Suspension and What Is It Used For?

 

Acidex Advance Oral Suspension is an over-the-counter alginate-antacid medicine used to relieve the symptoms of heartburn, gastro-oesophageal reflux, and indigestion. It works by forming a protective raft on top of stomach contents and neutralising excess stomach acid. The peppermint flavour makes it more palatable, and the 500ml bottle provides a generous supply for ongoing symptom management. It is suitable for adults and young people aged 12 and over.

 

What Do You Need to Know Before Using Acidex Advance Oral Suspension?

 

Before taking this suspension, it's important to check whether it's appropriate for you. Do not use Acidex Advance if any of the following apply:

  • You are allergic to sodium alginate, sodium bicarbonate, calcium carbonate, or any other ingredient in the suspension
  • You have been told to follow a low-sodium or sodium-restricted diet
  • You have severe kidney (renal) impairment
  • You are under 12 years of age (unless directed by a doctor)
  • You are pregnant or breastfeeding — consult your GP or midwife first

You should also be aware of potential interactions with other medicines. Antacid-containing products can affect the absorption of certain drugs. Separate doses of Acidex Advance from other medicines by at least 2 hours. Known interactions include:

  • Tetracycline antibiotics — absorption may be reduced
  • Iron supplements — antacids can impair iron absorption
  • Some antifungal medicines (e.g. ketoconazole) — reduced absorption possible
  • Bisphosphonates (e.g. alendronic acid) — timing of doses is critical

 

How Should You Use Acidex Advance Oral Suspension?

 

Always use this medicine exactly as described on the label or as directed by your pharmacist. Shake the bottle well before each use to ensure the suspension is evenly mixed.

  1. Shake the bottle thoroughly before measuring your dose.
  2. Use the measuring cup provided to measure the correct volume.
  3. Take the suspension after meals and at bedtime — do not dilute it with water.
  4. Swallow the dose directly; do not chew or mix with food.
  5. Replace the cap securely after each use.
Indication Age Group Dose Frequency
Heartburn / acid reflux Adults and children 12+ 10–20ml After meals and at bedtime (up to 4 times daily)
Indigestion Adults and children 12+ 10–20ml After meals and at bedtime (up to 4 times daily)
Children under 12 Under 12 years Not recommended Seek medical advice

 

What Are the Possible Side Effects of Acidex Advance Oral Suspension?

 

Like all medicines, Acidex Advance can cause side effects, although not everyone experiences them. Most side effects are mild and resolve on their own.

Common side effects (may affect up to 1 in 10 people):

  • Bloating or flatulence
  • Nausea
  • Mild stomach discomfort

Less common side effects (may affect up to 1 in 100 people):

  • Constipation or diarrhoea — if you experience persistent changes in bowel habits, you can explore our constipation treatments or diarrhoea remedies for additional support
  • Hypersensitivity reactions (rash, itching) — stop use immediately and seek medical advice
  • Raised blood sodium levels with prolonged high-dose use — particularly relevant if you have heart or kidney conditions

If you experience any serious or unexpected side effects, stop taking the suspension and contact your GP or call NHS 111 immediately.

 

How Should You Store Acidex Advance Oral Suspension?

 

Correct storage helps maintain the effectiveness and safety of the suspension. Follow these guidelines:

  • Store below 25°C in a cool, dry place
  • Do not freeze the suspension — freezing will damage the formulation
  • Keep the bottle tightly closed when not in use
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the label
  • Do not dispose of medicines via wastewater or household waste — return unused medicine to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Acidex Advance Oral Suspension online in the UK?

You can buy Acidex Advance Oral Suspension Peppermint 500ml directly from Cured Pharmacy, a GPhC-registered online pharmacy. It is available without a prescription as an over-the-counter general sale medicine. Simply add it to your basket and it will be dispatched to your door.

How does Acidex Advance Oral Suspension work in the body?

Acidex Advance works through a dual mechanism: sodium alginate reacts with stomach acid to form a gel-like raft that floats on top of stomach contents, physically preventing acid from rising into the oesophagus. At the same time, sodium bicarbonate and calcium carbonate neutralise excess gastric acid, reducing the burning sensation associated with heartburn and reflux.

How do I use Acidex Advance Oral Suspension step by step?

Using Acidex Advance correctly is straightforward. Follow these steps:

  1. Shake the bottle well before each use.
  2. Measure 10–20ml using the measuring cup provided.
  3. Take the dose after meals and at bedtime — do not dilute with water.
  4. Swallow directly and replace the cap securely.
What is the correct dose of Acidex Advance Oral Suspension for adults?

The recommended adult dose is 10–20ml taken after meals and at bedtime, up to four times daily. You should not exceed this dose unless advised by a healthcare professional. If symptoms do not improve within 7 days, consult your GP.

When is the best time to take Acidex Advance Oral Suspension?

The most effective time to take Acidex Advance is after meals and at bedtime. Taking it after eating allows the alginate raft to form on top of the stomach contents, providing the best protection against acid rising into the oesophagus. The bedtime dose is particularly helpful for people who experience night-time reflux or regurgitation.

What are the side effects of Acidex Advance Oral Suspension?

Side effects are uncommon but can include:

  • Bloating or flatulence
  • Nausea or mild stomach discomfort
  • Constipation or diarrhoea with prolonged use

If you experience a rash, swelling, or difficulty breathing, stop use immediately and seek urgent medical attention as these may indicate an allergic reaction.

Who should not take Acidex Advance Oral Suspension?

This suspension is not suitable for children under 12 years without medical advice, people on sodium-restricted diets, or those with severe kidney impairment. Pregnant or breastfeeding women should consult their GP or midwife before use. Always check the full list of ingredients if you have known allergies.

Can I take Acidex Advance Oral Suspension during pregnancy?

Heartburn is very common during pregnancy, but you should always speak to your GP or midwife before taking any medicine, including antacid preparations like Acidex Advance. The sodium content in this product may be a consideration during pregnancy, particularly if you have been advised to watch your salt intake. Your healthcare provider can recommend the safest option for you.

How long can I use Acidex Advance Oral Suspension for?

Acidex Advance is designed for short-term relief of heartburn and indigestion. If you need to use it for more than 7 consecutive days, or if your symptoms worsen or change, you should seek advice from your GP. Persistent reflux symptoms can sometimes indicate an underlying condition such as gastro-oesophageal reflux disease (GORD) that requires further assessment.

What happens if I miss a dose of Acidex Advance Oral Suspension?

If you miss a dose, simply take it as soon as you remember — unless it is nearly time for your next dose, in which case skip the missed one. Do not take a double dose to make up for a missed one. Acidex Advance is taken as needed for symptom relief, so strict timing is less critical than with some other medicines.

Can Acidex Advance Oral Suspension interact with other medicines?

Yes, the antacid components in Acidex Advance can affect the absorption of certain medicines. Known interactions include:

  • Tetracycline antibiotics
  • Iron supplements
  • Bisphosphonates (e.g. alendronic acid)
  • Some antifungal medicines (e.g. ketoconazole)

To minimise the risk of interactions, take Acidex Advance at least 2 hours apart from other medicines. Always tell your pharmacist about all medicines you are taking.

Is Acidex Advance Oral Suspension suitable for children?

Acidex Advance Oral Suspension is not recommended for children under 12 years of age unless directed by a doctor. For children aged 12 and over, the adult dose applies. If your child is younger and experiencing reflux or indigestion symptoms, speak to your GP or health visitor for appropriate advice. You can also explore our baby and toddler health products for age-appropriate options.

What are the alternatives to Acidex Advance Oral Suspension?

Common alternatives include other alginate-antacid suspensions such as Gaviscon Advance, or simple antacid liquids containing magnesium hydroxide or aluminium hydroxide. Proton pump inhibitors (PPIs) such as omeprazole are available for more persistent reflux but require a different mechanism of action and may need a prescription for longer courses. Browse our full indigestion range to compare available options.

Does Acidex Advance Oral Suspension contain gluten or allergens?

Acidex Advance Oral Suspension does not contain gluten, but you should always check the full patient information leaflet for a complete list of excipients and potential allergens before use. If you have a known allergy to any ingredient, do not use this product and consult your pharmacist for an alternative. The peppermint flavouring is derived from peppermint oil.

What are the latest findings on alginate-antacid suspensions for reflux?

Alginate-antacid preparations have been well studied and are recommended by the NHS as a first-line treatment for mild to moderate heartburn and gastro-oesophageal reflux. Clinical evidence supports their effectiveness in reducing reflux episodes and symptom severity, particularly when taken after meals. They are generally considered safe for short-term use in adults and adolescents aged 12 and over.

How Should You Use Acidex Advance Oral Suspension?

Using Acidex Advance correctly makes a real difference to how well it works. Always shake the bottle thoroughly before measuring your dose — the suspension can settle between uses, and an unmixed dose may be less effective. Use the measuring cup provided rather than a household spoon, as accurate dosing matters.

Follow these steps each time you take a dose:

What Is the Correct Dose of Acidex Advance Oral Suspension?

The dose varies depending on your age and the severity of your symptoms. Always follow the dosage instructions on the label or as directed by your pharmacist. Do not exceed the maximum daily dose.

When Is the Best Time to Use Acidex Advance Oral Suspension?

Timing your dose correctly is key to getting the most benefit from Acidex Advance. Taking it after meals — rather than before — allows the alginate to react with the stomach acid already present and form an effective raft on top of the stomach contents. This raft then acts as a physical barrier, reducing the likelihood of acid escaping upwards into the oesophagus.

The bedtime dose is particularly valuable if you suffer from night-time heartburn or wake with a sour taste in your mouth. Lying down can worsen reflux, so taking a dose just before sleep helps maintain the protective raft throughout the night.

How Long Can You Use Acidex Advance Oral Suspension For?

Acidex Advance is intended for short-term use to manage occasional or mild heartburn and indigestion. Most people find their symptoms settle within a few days of consistent use. However, if you are still relying on it after 7 consecutive days, or if your symptoms are getting worse rather than better, you should stop self-treating and speak to your GP.

Prolonged use without medical review is not recommended, particularly in people with kidney problems or those on sodium-restricted diets, as the sodium content of the suspension could become a concern over time. Your GP can assess whether a longer-term treatment strategy — such as a proton pump inhibitor — might be more appropriate for you.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Acidex Advance Oral Suspension?

Most people tolerate Acidex Advance Oral Suspension well, and side effects are generally mild when they do occur. The most frequently reported issues relate to the digestive system, which is unsurprising given that this medicine acts directly in the stomach.

  • Bloating or a feeling of fullness
  • Flatulence (wind)
  • Nausea
  • Mild stomach discomfort or cramping

What Are the Less Common Side Effects of Acidex Advance Oral Suspension?

Less commonly, some people may experience changes in bowel habits or other digestive effects. These are more likely with prolonged or high-dose use and usually resolve once you stop taking the suspension.

  • Constipation — particularly with calcium carbonate-containing antacids
  • Diarrhoea — less common but possible
  • Raised blood sodium levels (hypernatraemia) with prolonged high-dose use — more relevant in people with heart failure, kidney disease, or hypertension
  • Hypercalcaemia (raised blood calcium) with excessive long-term use

What Are the Serious Side Effects of Acidex Advance Oral Suspension?

Serious side effects are rare but require immediate attention. If you notice any of the following after taking Acidex Advance, stop use straight away and seek urgent medical help.

  • Signs of an allergic reaction: skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Severe abdominal pain that is new or worsening
  • Vomiting blood or passing black, tarry stools — these are not side effects of Acidex Advance but are warning signs of a more serious condition requiring urgent assessment

What Should You Do If You Experience Side Effects of Acidex Advance Oral Suspension?

For mild side effects such as bloating or nausea, these often settle on their own without any action needed. Reducing your dose slightly or ensuring you take the suspension after food rather than on an empty stomach may help. If side effects persist or are bothering you, speak to your pharmacist — they can advise whether to continue, adjust your dose, or switch to an alternative.

For any serious or unexpected reaction, stop taking the suspension immediately and contact your GP or call NHS 111. In an emergency — such as difficulty breathing or severe swelling — call 999 without delay.

Can Acidex Advance Oral Suspension Interact With Other Medicines?

Yes. The antacid components in Acidex Advance can interfere with the absorption of several medicines if taken at the same time. This is because antacids alter the pH of the stomach, which can affect how other drugs are absorbed into the bloodstream. To reduce this risk, always take Acidex Advance at least 2 hours before or after other medicines. Medicines most likely to be affected include tetracycline antibiotics, iron supplements, bisphosphonates, and some antifungal agents. Always inform your pharmacist of all medicines, supplements, and herbal remedies you are taking before starting Acidex Advance.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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