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Oraldene Mouthwash – 200ml

Oraldene Mouthwash – 200ml

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  • ✔️ Targets bacteria and fungi causing mouth ulcers and gingivitis
  • ✔️ Hexetidine 0.1% adheres to oral tissues for lasting antiseptic action
  • ✔️ Relieves sore throat discomfort with a simple 30-second gargle
  • ✔️ Suitable for adults and children aged six and over
  • ✔️ No prescription needed — ready to use straight from the bottle

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What Is Oraldene Mouthwash and How Does It Help?

 

Oraldene mouthwash is a well-established antiseptic oromucosal solution containing hexetidine 0.1% w/v. It has been used in the UK for decades to help manage a range of mouth and throat conditions — from painful mouth ulcers and inflamed gums to minor throat infections. If you've ever dealt with the discomfort of a mouth ulcer that just won't settle, you'll know how much relief a targeted antiseptic rinse can offer. At just £4.49 for a 200ml bottle, it's an accessible option for everyday oral health. You can explore our full range of oral health products at Cured Pharmacy.

Hexetidine works against a broad spectrum of bacteria and fungi, making it suitable for conditions where microbial activity is contributing to symptoms. It's available over the counter without a prescription, which means you can pick it up quickly when you need it most.

 

How Does Oraldene Mouthwash Work in the Mouth and Throat?

 

The active ingredient, hexetidine 0.1% w/v, is an antiseptic that acts directly on the lining of the mouth and throat. It works by disrupting the cell membranes of bacteria and fungi, preventing them from multiplying and causing further infection or irritation.

  • Binds to oral mucosa and tooth surfaces, providing a sustained antiseptic effect even after rinsing
  • Active against a wide range of gram-positive and gram-negative bacteria
  • Also has antifungal properties, making it useful where Candida species may be involved
  • Reduces bacterial plaque formation when used as part of a regular oral hygiene routine

Because hexetidine adheres to oral tissues, it continues to work for a period after you've spat the mouthwash out — which is one reason it's used just two to three times daily rather than after every meal.

 

Who Should Use Oraldene Mouthwash?

 

Oraldene is suitable for adults and children aged 6 and over. It's particularly useful if you're dealing with any of the following conditions where antiseptic oral care can make a real difference:

  • Mouth ulcers (aphthous ulcers) causing pain and discomfort
  • Gingivitis or inflamed, bleeding gums
  • Minor throat infections or pharyngitis
  • Post-dental procedure oral hygiene support
  • Oral thrush (candidiasis) as an adjunct to prescribed antifungal treatment

It is not suitable for children under 6 years of age. If you're pregnant, breastfeeding, or have an existing medical condition affecting your mouth or throat, speak to your pharmacist or GP before use. For broader pain management needs alongside oral care, our pain relief collection may also be worth exploring.

 

How Does Oraldene Mouthwash Compare to Other Antiseptic Mouthwashes?

 

Feature Oraldene (Hexetidine 0.1%) Corsodyl (Chlorhexidine 0.2%)
Active ingredient Hexetidine Chlorhexidine gluconate
Antifungal action Yes Yes
Risk of tooth staining Low Higher with prolonged use
Suitable for children (6+) Yes Yes (with caution)
Available OTC Yes Yes

 

Is Oraldene Mouthwash Safe to Store at Home?

 

Yes. Oraldene mouthwash should be stored below 25°C, away from direct sunlight, and kept out of the reach and sight of children. Do not use the product after the expiry date printed on the bottle. The 200ml size is practical for home use and fits easily in a bathroom cabinet.

If you accidentally swallow a large amount, seek medical advice immediately. This product is for oromucosal use only — rinse and spit, never swallow. For related ear, nose, and throat concerns, you might also find our ear, nose and throat range helpful.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Oraldene Mouthwash 200ml specifications
Treatment category Oral antiseptic / Oral hygiene
Active ingredient Hexetidine 0.1% w/v
Mechanism of action Disrupts bacterial and fungal cell membranes; adheres to oral mucosa for sustained effect
Suitable for Adults and children aged 6 and over
Pack size 200ml
Strength 0.1% w/v hexetidine
UK classification General Sale List (GSL)
Drug class Antiseptic (oromucosal)
Preparation Oromucosal solution
Route of administration Oromucosal (rinse/gargle)

Specifications of Oraldene Mouthwash 200ml

 

What Is Oraldene Mouthwash and What Is It Used For?

 

Oraldene mouthwash is an antiseptic oromucosal solution containing hexetidine 0.1% w/v. It is used to treat and relieve symptoms associated with infections and inflammation of the mouth and throat. Conditions it is commonly used for include mouth ulcers, gingivitis, pharyngitis, and as a supportive measure following dental procedures. It may also be used as an adjunct in the management of oral candidiasis (oral thrush). The NHS advises that good oral hygiene, including the use of appropriate antiseptic rinses, can help manage many common mouth conditions.

 

What Do You Need to Know Before Using Oraldene Mouthwash?

 

Before using Oraldene, it's important to check whether it is appropriate for you. Do not use this product if any of the following apply:

  • You are allergic to hexetidine or any other ingredient in the formulation
  • You are under 6 years of age (not suitable for young children)
  • You have ulcerative stomatitis or atrophic oral conditions that may be worsened by antiseptic rinses
  • You have been advised by your dentist or doctor to avoid antiseptic mouthwashes

Take care and speak to your pharmacist or GP if you are pregnant or breastfeeding, or if you have any condition affecting the lining of your mouth. The following interactions should also be noted:

  • No clinically significant drug interactions with hexetidine mouthwash have been widely reported
  • If you are using other oromucosal preparations, allow adequate time between applications
  • Avoid using immediately after eating or drinking, as this may reduce effectiveness

 

How Should You Use Oraldene Mouthwash Correctly?

 

Always use Oraldene exactly as described in this leaflet or as directed by your pharmacist or dentist. Do not dilute the solution — it is ready to use straight from the bottle.

  1. Measure approximately 15ml of Oraldene mouthwash using the cap or a measuring cup
  2. Take the solution into your mouth
  3. Rinse thoroughly around your mouth for at least 30 seconds, or gargle if treating a sore throat
  4. Spit the solution out completely — do not swallow
  5. Do not eat, drink, or rinse your mouth with water for at least 30 minutes after use
  6. Repeat two to three times daily, or as directed
Indication Age Group Dose Frequency
Mouth ulcers / gingivitis Adults & children 6+ 15ml undiluted 2–3 times daily
Sore throat / pharyngitis Adults & children 6+ 15ml undiluted (gargle) 2–3 times daily
Post-dental procedure hygiene Adults 15ml undiluted As directed by dentist
Children under 6 Not applicable Do not use

 

What Are the Possible Side Effects of Oraldene Mouthwash?

 

Like all medicines, Oraldene can cause side effects, although not everyone experiences them. Most side effects are mild and resolve on their own. If you're concerned about any reaction, stop use and speak to your pharmacist. You can also find general guidance on managing mouth conditions through the NHS website.

Common side effects:

  • Temporary burning or stinging sensation in the mouth or throat
  • Altered or unpleasant taste during or after use
  • Mild local irritation of the oral mucosa

Less common side effects:

  • Numbness or tingling of the tongue or gums
  • Dry mouth sensation
  • Hypersensitivity reactions (rash, swelling) — stop use immediately and seek medical advice if these occur

If you experience any signs of a serious allergic reaction — including swelling of the face, lips, or throat, or difficulty breathing — seek emergency medical attention immediately. For dental-related concerns alongside your oral care routine, our dental products collection has a range of supportive options.

 

How Should You Store Oraldene Mouthwash?

 

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Keep the bottle tightly closed when not in use
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the bottle or carton
  • Do not dispose of medicines via wastewater or household waste — return unused product to your pharmacist

If you have any questions about storage or suitability, your pharmacist at Cured Pharmacy is always happy to help. For other first aid and health essentials, take a look at our first aid collection.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Oraldene mouthwash online in the UK?

You can buy Oraldene mouthwash 200ml directly from Cured Pharmacy online for just £4.49, with no prescription required. It is classified as a General Sale List (GSL) medicine, meaning it is available over the counter. Simply add it to your basket and have it delivered to your door.

How does Oraldene mouthwash work in the body?

Oraldene contains hexetidine 0.1% w/v, which works by disrupting the cell membranes of bacteria and fungi present in the mouth and throat. This antiseptic action reduces microbial load, helping to relieve infection-related symptoms such as soreness, inflammation, and ulceration. Hexetidine also adheres to oral tissues, providing a sustained effect after rinsing.

How do I use Oraldene mouthwash step by step?

Measure 15ml of undiluted Oraldene using the bottle cap, swirl or gargle for around 30 seconds, then spit it out completely — never swallow. Avoid eating, drinking, or rinsing with water for at least 30 minutes afterwards to allow the antiseptic to continue working. Use two to three times daily unless your dentist or pharmacist advises otherwise.

What is the correct dose of Oraldene mouthwash for adults?

The standard adult dose is 15ml of undiluted solution, used as a mouthwash or gargle two to three times daily. Do not exceed this frequency without professional advice. The same dose applies to children aged 6 and over, always under adult supervision.

Can children use Oraldene mouthwash?

Oraldene mouthwash is suitable for children aged 6 and over, used under adult supervision. It must not be given to children under 6 years of age. If you are looking for oral health or general health products suitable for younger children, our baby and toddler collection may be more appropriate.

What are the side effects of Oraldene mouthwash?

Most people tolerate Oraldene well, but some may experience a temporary burning or stinging sensation, altered taste, or mild irritation of the mouth lining. Less commonly, numbness or tingling of the tongue may occur. If you notice any signs of an allergic reaction such as swelling or difficulty breathing, stop use immediately and seek urgent medical attention.

How do I manage side effects of Oraldene mouthwash?

If you experience a burning sensation, try not to rinse with water immediately after use — this is normal and usually settles within a few minutes. If taste disturbance persists or irritation worsens, stop using the product and speak to your pharmacist. Serious side effects are rare but should always be assessed by a healthcare professional promptly.

Can I use Oraldene mouthwash if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, you should consult your doctor or pharmacist before using Oraldene mouthwash. While the product is applied topically in the mouth and systemic absorption is considered low, professional guidance is always recommended during pregnancy and lactation. Your pharmacist can help you weigh up the benefits and any potential risks.

How long can I use Oraldene mouthwash for?

Oraldene is intended for short-term use to treat acute oral and throat conditions. If your symptoms have not improved after seven days of regular use, you should stop and consult your dentist, pharmacist, or GP. Prolonged use without professional review is not recommended, as persistent symptoms may indicate an underlying condition requiring further investigation.

What are the alternatives to Oraldene mouthwash?

Common alternatives include chlorhexidine gluconate mouthwashes (such as Corsodyl 0.2%), which are particularly effective for gingivitis and plaque control, and benzydamine hydrochloride mouthwashes (such as Difflam), which offer anti-inflammatory as well as antiseptic properties. Your pharmacist can advise on the most suitable option based on your specific symptoms. You can also browse our full oral health range for further options.

Does Oraldene mouthwash stain teeth?

Unlike chlorhexidine-based mouthwashes, hexetidine (the active ingredient in Oraldene) has a lower association with tooth staining, making it a preferable choice for those concerned about discolouration. However, maintaining good brushing habits alongside mouthwash use is always advisable. If you notice any unexpected changes to tooth colour, speak to your dentist.

Can I use Oraldene mouthwash after a tooth extraction?

You should always follow your dentist's specific post-operative instructions after a tooth extraction, as vigorous rinsing in the first 24 hours can dislodge the blood clot and delay healing. If your dentist has recommended an antiseptic mouthwash as part of your aftercare, Oraldene may be suitable — but confirm this with your dental team first. Gentle use after the initial healing period is generally considered appropriate.

What happens if I accidentally swallow Oraldene mouthwash?

Oraldene is not intended to be swallowed. If a small amount is accidentally ingested, it is unlikely to cause serious harm in adults, but you should seek medical advice if you feel unwell or if a child has swallowed a significant quantity. Contact NHS 111 or your nearest A&E if you are concerned. Always keep the bottle out of reach of children.

Is Oraldene mouthwash effective for oral thrush?

Hexetidine has demonstrated antifungal activity against Candida species in laboratory studies, and Oraldene may be used as a supportive measure alongside prescribed antifungal treatment for oral thrush. However, it is not a standalone treatment for oral candidiasis — if you suspect oral thrush, you should speak to your pharmacist or GP for appropriate antifungal therapy. You can also explore our thrush treatment range for further options.

What are the latest studies on hexetidine mouthwash?

Research into hexetidine has consistently supported its broad-spectrum antibacterial and antifungal activity in the oral cavity, with studies noting its ability to adhere to oral tissues and provide a sustained antiseptic effect. It has been used clinically for several decades and remains a recognised option in oral antiseptic therapy. For the most up-to-date clinical evidence, your pharmacist or dentist can provide guidance based on current literature.

How Should You Use Oraldene Mouthwash?

Oraldene mouthwash is straightforward to use, but following the correct technique makes a real difference to how effective it is. Always use the solution undiluted — do not add water before rinsing. The steps below will help you get the most from each use.

Never swallow Oraldene mouthwash. If you are supervising a child aged 6 or over, ensure they understand to spit the solution out fully.

What Is the Correct Dose of Oraldene Mouthwash?

The recommended dose is 15ml of undiluted solution per use. This applies to adults and children aged 6 and over. Do not use more than three times daily unless specifically directed by your dentist or pharmacist.

When Is the Best Time to Use Oraldene Mouthwash?

For best results, use Oraldene after brushing your teeth — this removes surface debris and allows the antiseptic to make direct contact with the oral mucosa. Using it after meals is also effective, as it helps clear food particles and reduce bacterial activity in the mouth. Avoid using it immediately before eating or drinking, as this reduces the contact time and limits its effectiveness.

If you are using it for a sore throat, gargling in the morning and evening — and once more during the day if needed — tends to provide the most consistent relief throughout the day.

How Long Can You Use Oraldene Mouthwash For?

Oraldene is designed for short-term use. Most acute conditions such as mouth ulcers or mild throat infections should begin to improve within a few days of regular use. If you have not noticed any improvement after seven days, stop using the product and consult your pharmacist, dentist, or GP — persistent symptoms may need further investigation or a different treatment approach.

Do not use Oraldene continuously over long periods without professional guidance. Your dentist or pharmacist can advise on whether ongoing use is appropriate for your individual circumstances.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Oraldene Mouthwash?

Most people use Oraldene without experiencing any significant problems. However, as with any medicine, some side effects can occur. The most commonly reported ones are mild and tend to resolve quickly after use.

  • Temporary burning or stinging sensation in the mouth or throat
  • Altered or unpleasant taste during or shortly after rinsing
  • Mild irritation of the oral mucosa (the lining of the mouth)

What Are the Less Common Side Effects of Oraldene Mouthwash?

Less frequently, some people may notice other effects that are worth being aware of. These are not common, but you should stop using the product and seek advice if they persist or cause concern.

  • Numbness or tingling of the tongue or gums
  • Dry mouth sensation
  • Temporary discolouration of the tongue (rare)
  • Increased sensitivity of the oral tissues

What Are the Serious Side Effects of Oraldene Mouthwash?

Serious side effects are rare but can occur in people who are hypersensitive to hexetidine or any other ingredient in the formulation. If you experience any of the following, stop using Oraldene immediately and seek urgent medical attention:

  • Swelling of the face, lips, tongue, or throat (angioedema)
  • Difficulty breathing or swallowing
  • Severe rash or hives
  • Sudden worsening of mouth or throat symptoms

These symptoms may indicate a serious allergic reaction (anaphylaxis), which requires emergency treatment. Call 999 or go to your nearest A&E immediately.

What Should You Do If You Experience Side Effects of Oraldene Mouthwash?

For mild side effects such as a brief burning sensation or taste change, no specific action is usually needed — these typically resolve within a few minutes of spitting out the solution. If irritation is persistent or worsening, discontinue use and speak to your pharmacist. You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk, which helps improve medicine safety monitoring in the UK.

Can Oraldene Mouthwash Interact With Other Medicines?

No clinically significant drug interactions with hexetidine mouthwash have been widely reported in the published literature. However, if you are using other oromucosal preparations — such as prescribed antifungal gels or medicated lozenges — allow adequate time between applications to avoid diluting the effect of either product. Always inform your pharmacist of all medicines you are currently taking, including over-the-counter products and supplements, so they can check for any potential interactions specific to your situation.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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