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Nutramigen 3 With LGG Vanilla Flavour - 400g

Nutramigen 3 With LGG Vanilla Flavour - 400g

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What Is Nutramigen 3 with LGG and Who Is It For?

 

If your toddler has been diagnosed with cow's milk allergy (CMA), finding the right formula can feel overwhelming. Nutramigen 3 with LGG is an extensively hydrolysed, hypoallergenic toddler formula designed specifically for children from 1 year of age who cannot tolerate intact cow's milk proteins. It comes in a vanilla flavour to make it more palatable for toddlers who may be transitioning from an earlier stage formula, and each 400g tin provides a convenient supply for families managing CMA day to day. You can find it alongside other products in our baby and toddler range at Cured Pharmacy.

Cow's milk allergy affects an estimated 2–3% of infants in the UK, according to NHS guidance. It can cause a wide range of symptoms — from skin reactions and digestive upset to more serious responses — and it requires careful dietary management, particularly in the first years of life. Nutramigen 3 with LGG is formulated to meet the nutritional needs of toddlers while avoiding the allergenic proteins found in standard cow's milk-based formulas.

 

How Does Nutramigen 3 With LGG Work?

 

The science behind this formula centres on two key elements: extensively hydrolysed protein and the probiotic strain Lactobacillus rhamnosus GG (LGG).

  • Extensively hydrolysed casein: The cow's milk proteins in Nutramigen 3 are broken down (hydrolysed) into very small peptide fragments. These fragments are too small to be recognised by the immune system as allergens, which means they are unlikely to trigger an allergic reaction in most children with CMA.
  • LGG probiotic: Lactobacillus rhamnosus GG is one of the most studied probiotic strains in paediatric nutrition. Research suggests it may support gut barrier function and play a role in helping toddlers develop tolerance to cow's milk proteins over time.
  • Lactose-free formulation: The formula contains no lactose, which is important because some children with CMA also have secondary lactose intolerance due to gut inflammation.
  • Age-appropriate nutrition: Nutramigen 3 is nutritionally tailored for toddlers from 1 year, providing vitamins, minerals, and energy to complement a weaning diet.

 

Who Should Use Nutramigen 3 With LGG?

 

This formula is intended for toddlers aged 1 year and over who have a confirmed or suspected diagnosis of cow's milk allergy. It should always be used under the guidance of a healthcare professional — typically a GP, paediatrician, or registered dietitian — who can confirm the diagnosis and advise on the appropriate formula stage.

  • Toddlers aged 1 year and over with diagnosed IgE-mediated or non-IgE-mediated cow's milk allergy
  • Children who have been using Nutramigen 2 and are ready to progress to the next stage
  • Toddlers who require a lactose-free, hypoallergenic formula to complement a mixed diet
  • Children whose healthcare team has recommended an extensively hydrolysed formula rather than an amino acid-based formula

It is not suitable as the sole source of nutrition for infants under 12 months. If you are unsure whether this formula is right for your child, always speak to your GP or health visitor before switching.

 

How Does Nutramigen 3 Compare to Other Hypoallergenic Formulas?

 

Feature Nutramigen 3 With LGG Amino Acid Formula (e.g. Neocate)
Protein source Extensively hydrolysed casein Free amino acids (no intact protein)
Suitable for Most children with CMA (IgE & non-IgE) Severe or multiple food allergies, or where eHF has failed
Contains probiotic (LGG) Yes No (varies by product)
Lactose-free Yes Yes
Age range From 1 year From birth (product-dependent)

 

How Should You Store Nutramigen 3 With LGG?

 

Store the unopened tin in a cool, dry place away from direct sunlight. Once opened, keep the tin tightly sealed and use within 4 weeks. Always prepare feeds using freshly boiled water that has cooled to no less than 70°C to reduce the risk of bacterial contamination. Prepared feeds should be used immediately where possible; if you need to store a prepared feed, refrigerate it promptly and use within 24 hours. Never freeze prepared formula.

If your child has additional health needs or you are managing other conditions alongside CMA — such as digestive discomfort — our vitamins and supplements range may also be of interest for supporting your toddler's overall nutrition under professional guidance.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Nutramigen 3 With LGG Vanilla Flavour 400g specifications
Treatment category Hypoallergenic toddler formula / Cow's milk allergy management
Mechanism of action Extensively hydrolysed casein protein reduces allergenicity; LGG probiotic supports gut health
Effective for Cow's milk allergy (IgE-mediated and non-IgE-mediated) in toddlers from 1 year
Suitable for Toddlers aged 1 year and over
Active ingredient Extensively hydrolysed casein protein with Lactobacillus rhamnosus GG (LGG)
Pack size 400g
UK classification Food for Special Medical Purposes (FSMP)
Preparation Powder for oral solution (reconstituted with water)
Route of administration Oral
Flavour Vanilla
Lactose-free Yes

Specifications of Nutramigen 3 With LGG Vanilla Flavour 400g

 

What Is Nutramigen 3 With LGG and What Is It Used For?

 

Nutramigen 3 With LGG Vanilla Flavour is a Food for Special Medical Purposes (FSMP) — a category of nutritional product regulated under UK food law for the dietary management of specific medical conditions. It is used for the management of cow's milk allergy (CMA) in toddlers aged 1 year and over. CMA is one of the most common food allergies in young children in the UK, and it occurs when the immune system reacts abnormally to proteins found in cow's milk.

The NHS advises that children with CMA need to avoid cow's milk and products containing cow's milk protein, and that suitable alternative formulas should be used to ensure adequate nutrition. Nutramigen 3 with LGG provides a nutritionally complete option for toddlers who still rely partly on formula alongside solid foods. It is not intended to replace a balanced, age-appropriate diet but to complement it.

 

What Do You Need to Know Before Using Nutramigen 3 With LGG?

 

Before starting your toddler on this formula, there are important contraindications and precautions to be aware of:

  • Do not use in infants under 12 months as the sole source of nutrition without medical supervision
  • Not suitable for children with galactosaemia (a rare metabolic disorder affecting galactose processing)
  • Not suitable for children with a confirmed allergy to any of the ingredients listed on the tin
  • A small number of children with severe CMA may not tolerate extensively hydrolysed formulas and may require an amino acid-based formula — always confirm suitability with your healthcare team
  • Always use under the supervision of a healthcare professional for a medically diagnosed condition
  • Do not use as a supplement to a normal diet without medical advice

There are no known significant drug interactions with Nutramigen 3 With LGG. However, if your child is taking any prescribed medicines or nutritional supplements, always inform your GP or pharmacist before introducing a new formula.

  • No clinically significant interactions with common paediatric medicines have been identified
  • If your child takes iron supplements or other micronutrient supplements, discuss with your dietitian whether these remain necessary alongside this formula

 

How Should You Use Nutramigen 3 With LGG?

 

Always follow the preparation instructions printed on the tin. Incorrect preparation — whether too concentrated or too dilute — can affect your toddler's nutrition and hydration. The steps below reflect standard guidance for powdered infant and toddler formulas:

  1. Wash your hands thoroughly with soap and water before preparing the feed.
  2. Sterilise all feeding equipment (bottles, teats, lids) before use.
  3. Boil fresh tap water and allow it to cool to no less than 70°C (use within 30 minutes of boiling).
  4. Pour the required amount of water into the sterilised bottle first.
  5. Using the scoop provided, measure the correct number of level scoops as directed on the tin — do not pack the powder or add extra scoops.
  6. Add the powder to the water (not the other way around).
  7. Cap the bottle and shake well until the powder is fully dissolved.
  8. Cool the feed to a safe drinking temperature before offering it to your toddler. Test on the inside of your wrist.
  9. Discard any unused feed after 2 hours at room temperature, or within 24 hours if refrigerated.
Age Group Formula Stage Typical Daily Volume Frequency
12 months and over Nutramigen 3 As directed by healthcare professional As part of a mixed diet — typically 1–2 feeds per day

The exact volume and frequency should always be confirmed by your GP, paediatrician, or registered dietitian based on your child's individual nutritional needs.

 

What Are the Possible Side Effects of Nutramigen 3 With LGG?

 

As with any formula change, some toddlers may experience a period of adjustment when first starting Nutramigen 3. Most effects are mild and temporary. If you are concerned about your child's reaction, speak to your GP or health visitor promptly. You may also find it helpful to browse our allergy section for additional resources on managing allergic conditions in children.

Common side effects (may affect some toddlers during transition):

  • Loose or softer stools
  • Change in stool colour (stools may appear greener or darker)
  • Change in stool odour
  • Temporary increase in wind or bloating

Less common side effects:

  • Constipation in some children
  • Refusal of the formula due to taste difference (particularly when transitioning from a standard formula)
  • Skin rash — if this occurs, stop use and seek medical advice, as it may indicate the formula is not suitable for your child

If your toddler develops any signs of a serious allergic reaction — including swelling of the face or throat, difficulty breathing, or a sudden widespread rash — seek emergency medical attention immediately.

 

How Should You Store Nutramigen 3 With LGG?

 

  • Store the unopened tin in a cool, dry place below 25°C, away from direct sunlight and heat sources
  • Once opened, keep the tin tightly sealed and use within 4 weeks
  • Do not store prepared feeds at room temperature for more than 2 hours
  • Refrigerate prepared feeds promptly and use within 24 hours
  • Never freeze the powder or prepared feeds
  • Keep out of reach of children (the tin itself, not the prepared feed)
  • Check the expiry date on the base of the tin before use and do not use after the date shown

For families managing multiple health needs alongside CMA, our baby and toddler collection includes a range of products to support your child's health and wellbeing.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Nutramigen 3 with LGG online in the UK?

You can buy Nutramigen 3 With LGG Vanilla Flavour 400g directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for £15.99. It is also stocked in some high street pharmacies, though availability can vary. Ordering online is often the most convenient option, especially if your toddler relies on it regularly as part of their allergy management plan.

What age is Nutramigen 3 with LGG suitable for?

Nutramigen 3 With LGG is designed for toddlers aged 1 year and over who have been diagnosed with cow's milk allergy. It is not intended as the sole source of nutrition for infants under 12 months. At this stage, it is used alongside a mixed weaning diet rather than as a complete sole feed.

How does Nutramigen 3 with LGG work in the body?

The formula uses extensively hydrolysed casein protein — cow's milk protein that has been broken down into very small fragments — so the immune system is far less likely to recognise and react to it. The added probiotic LGG (Lactobacillus rhamnosus GG) supports gut health and may assist in the development of tolerance to cow's milk proteins over time. Together, these two components make it a well-studied option for managing cow's milk allergy in toddlers.

Is Nutramigen 3 available on prescription in the UK?

Nutramigen formulas can be prescribed by a GP or paediatric dietitian for a confirmed diagnosis of cow's milk allergy, but Nutramigen 3 (for toddlers over 1 year) is also available to purchase over the counter without a prescription. Whether your child qualifies for a prescription depends on their age, diagnosis, and local NHS prescribing guidelines — speak to your GP or health visitor for guidance. You can also purchase it directly from our baby and toddler collection at Cured Pharmacy.

What is the difference between Nutramigen 1, 2, and 3?

Nutramigen 1 is formulated for infants from birth, Nutramigen 2 is for infants from 6 months, and Nutramigen 3 is for toddlers from 1 year of age. Each stage is nutritionally tailored to the developmental and dietary needs of that specific age group. If you are unsure which stage is right for your child, your GP or dietitian can advise on the appropriate transition.

Does Nutramigen 3 with LGG contain lactose?

No — Nutramigen 3 With LGG is lactose-free, which is important because some children with cow's milk allergy also develop secondary lactose intolerance as a result of gut inflammation. Removing lactose from the formula helps reduce digestive discomfort in these children. Always check the ingredient list on the tin if your child has additional dietary requirements.

How do I prepare Nutramigen 3 formula step by step?

Wash your hands and sterilise all feeding equipment before you begin. Boil fresh tap water and allow it to cool to no less than 70°C, then pour the required amount of water into the sterilised bottle before adding the correct number of level scoops of powder as directed on the tin. Shake well, cool to a safe drinking temperature, and offer to your toddler — discarding any unused feed after 2 hours at room temperature or within 24 hours if refrigerated.

What are the side effects of Nutramigen 3 with LGG?

Some toddlers experience loose stools, a change in stool colour or odour, or temporary wind and bloating when first transitioning to Nutramigen 3 With LGG. These effects are usually mild and settle within a few days as the digestive system adjusts to the new formula. If your child develops a skin rash, persistent vomiting, or any signs of a serious allergic reaction, stop use and seek medical advice promptly.

How long does a 400g tin of Nutramigen 3 last?

Once opened, a 400g tin of Nutramigen 3 should be used within 4 weeks, regardless of the expiry date on the tin. The number of feeds you get from each tin will depend on how many scoops per feed your healthcare team has recommended and how many feeds your toddler has per day. Most families find it helpful to keep a spare tin in stock to avoid running out.

Can Nutramigen 3 with LGG be used alongside solid foods?

Yes — at the toddler stage (from 1 year), Nutramigen 3 With LGG is designed to complement a mixed weaning diet rather than replace it. It provides important nutrients, including calcium and vitamins, that support growth and development alongside age-appropriate solid foods. Your dietitian can advise on the right balance of formula and food for your child's individual needs.

What are the alternatives to Nutramigen 3 for toddlers with cow's milk allergy?

Alternatives to Nutramigen 3 include other extensively hydrolysed formulas (eHFs) such as Aptamil Pepti 2, or amino acid-based formulas (AAFs) such as Neocate Junior for children who do not tolerate eHFs. The right choice depends on the severity of your child's allergy and their response to previous formulas — always discuss alternatives with your GP or paediatric dietitian before switching. You can also explore our allergy section for further support resources.

How long does a toddler stay on Nutramigen 3 with LGG?

The duration of use varies from child to child and is determined by their healthcare team. Many children with cow's milk allergy naturally outgrow it by the age of 3–5 years, at which point a supervised milk ladder or reintroduction protocol may be recommended. Your GP or dietitian will guide you on when and how to attempt reintroduction of cow's milk into your toddler's diet.

Is Nutramigen 3 with LGG suitable for toddlers with multiple food allergies?

Nutramigen 3 With LGG is specifically formulated for cow's milk allergy and may not be appropriate for toddlers with multiple or severe food allergies. Children with multiple food allergies or those who have not responded to extensively hydrolysed formulas may require an amino acid-based formula instead. Always seek specialist dietetic advice if your child has complex allergy needs.

What does the latest research say about LGG in infant and toddler formulas?

Research into Lactobacillus rhamnosus GG (LGG) in the context of cow's milk allergy management has shown promising results, with some studies suggesting it may support faster development of tolerance to cow's milk proteins when added to extensively hydrolysed formulas. The evidence base continues to grow, and LGG remains one of the most studied probiotic strains in paediatric nutrition. Your healthcare team will be up to date with current clinical guidance on its use.

What should I do if my toddler refuses Nutramigen 3 because of the taste?

It is not uncommon for toddlers to initially refuse extensively hydrolysed formulas due to their distinct taste, which differs from standard cow's milk-based formulas. The vanilla flavour in Nutramigen 3 With LGG is specifically included to improve palatability and encourage acceptance. If your toddler continues to refuse it, speak to your dietitian — they may suggest gradual introduction strategies or assess whether an alternative formula is more appropriate.

How Should You Use Nutramigen 3 With LGG Vanilla Flavour?

Always prepare Nutramigen 3 With LGG following the instructions printed on the tin. Correct preparation is essential to ensure your toddler receives the right balance of nutrients and to minimise the risk of bacterial contamination. Never add extra scoops of powder or dilute the formula beyond the recommended ratio, as this can affect your child's nutrition and hydration.

Follow these steps each time you prepare a feed:

What Is the Correct Dose of Nutramigen 3 With LGG?

The number of feeds and volume per feed should be determined by your GP, paediatrician, or registered dietitian based on your toddler's individual nutritional requirements, weight, and dietary intake from solid foods. The table below provides general guidance only — always follow the specific advice given by your healthcare team.

When Is the Best Time to Use Nutramigen 3 With LGG?

There is no single fixed time of day that is clinically required for giving Nutramigen 3 With LGG. Most families find it easiest to incorporate formula feeds into their toddler's existing routine — for example, as a morning drink, a mid-afternoon feed, or as part of a bedtime routine. Consistency helps toddlers accept the formula more readily, particularly during the initial transition period when the taste may be unfamiliar.

If your toddler is eating three meals a day, formula feeds are best offered between meals or at the start and end of the day to avoid displacing appetite for solid foods. Your dietitian can advise on the best timing for your child's specific routine and nutritional needs.

How Long Can You Use Nutramigen 3 With LGG For?

The duration of use is determined entirely by your child's healthcare team. Many children with cow's milk allergy naturally develop tolerance and outgrow the condition by the age of 3–5 years, at which point a supervised reintroduction protocol (often called a milk ladder) may be recommended. Until that point, continuing with an appropriate hypoallergenic formula ensures your toddler's nutritional needs are met without exposure to allergenic milk proteins.

Never stop or switch formula without first discussing it with your GP or dietitian, as an unsupervised change could put your child's nutrition or allergy management at risk. Regular reviews with your healthcare team will help determine the right time to transition away from the formula.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

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Content last updated: 31 Mar 2025

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