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Nurofen Period Pain – 16 Gel Capsules

Nurofen Period Pain – 16 Gel Capsules

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  • ✔️ Targets menstrual cramp pain at the source via prostaglandin inhibition
  • ✔️ Liquid-filled gel capsule format for faster ibuprofen absorption
  • ✔️ Suitable for women and girls aged 12 and over
  • ✔️ Each capsule contains ibuprofen lysine 342mg for effective relief
  • ✔️ Specifically formulated for dysmenorrhoea, not general pain

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What Are Nurofen Period Pain Ibuprofen Period Pain Tablets?

 

Period pain — medically known as dysmenorrhoea — affects a significant number of women and people who menstruate in the UK. It can range from a dull, nagging ache to sharp, debilitating cramps that interfere with daily life. Ibuprofen period pain tablets like Nurofen Period Pain are one of the most widely recommended over-the-counter options for managing this discomfort. Each pack contains 16 liquid-filled gel capsules, each containing ibuprofen lysine 342mg — equivalent to 200mg of ibuprofen — designed to get to work quickly when you need relief most. You can browse our full range of pain relief products if you're looking for additional options to manage discomfort.

Nurofen Period Pain is a P (pharmacy) medicine, meaning it's available without a prescription but should be used in line with the guidance on the label. It's specifically indicated for the relief of painful menstrual periods and is suitable for women and girls aged 12 and over.

 

How Do Nurofen Period Pain Gel Capsules Work?

 

Ibuprofen belongs to a class of medicines called non-steroidal anti-inflammatory drugs, or NSAIDs. During menstruation, the uterine lining releases chemicals called prostaglandins. These trigger uterine muscle contractions — and the higher the prostaglandin levels, the more intense the cramping tends to be. Ibuprofen works by blocking the enzymes (COX-1 and COX-2) responsible for producing prostaglandins, which in turn reduces both pain and inflammation.

  • Inhibits COX-1 and COX-2 enzymes to reduce prostaglandin production
  • Reduces uterine muscle contractions associated with menstrual pain
  • Provides anti-inflammatory and analgesic (pain-relieving) effects
  • Liquid-filled gel capsule format aids faster absorption compared to standard tablets

The ibuprofen lysine salt form used in these capsules is thought to be absorbed more rapidly than standard ibuprofen, which is why many people notice relief relatively quickly after taking a dose.

 

Who Is Nurofen Period Pain Suitable For?

 

These capsules are designed specifically for menstrual pain relief. They're a practical choice if you experience regular period cramps and want a targeted, fast-acting option. That said, they're not suitable for everyone — always read the label carefully before use.

  • Women and girls aged 12 and over experiencing painful periods
  • Those who prefer a liquid-filled capsule over a standard tablet
  • People who need relief at the onset of menstrual cramps
  • Those without contraindications to NSAIDs (see below for full list)

If you also experience other symptoms around your cycle — such as bloating, mood changes, or breast tenderness — it may be worth exploring our women's health range for complementary support options.

 

How Does Nurofen Period Pain Compare to Standard Ibuprofen Tablets?

 

Feature Nurofen Period Pain Gel Capsules Standard Ibuprofen 200mg Tablets
Active ingredient Ibuprofen lysine 342mg (= 200mg ibuprofen) Ibuprofen 200mg
Formulation Liquid-filled gel capsule Solid tablet
Onset of action Potentially faster absorption Standard absorption rate
Specific indication Menstrual pain (dysmenorrhoea) General pain, fever, inflammation

 

How Should You Store Nurofen Period Pain Gel Capsules?

 

Store below 25°C in a dry place, away from direct sunlight. Keep the pack out of reach and sight of children at all times. Do not use after the expiry date printed on the packaging. If you're unsure whether ibuprofen period pain tablets are right for your situation — for example, if you have a history of stomach problems, kidney issues, or are taking other regular medicines — speak to your pharmacist before use.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Nurofen Period Pain – 16 Gel Capsules specifications
Treatment category Menstrual pain relief (dysmenorrhoea)
Active ingredient Ibuprofen lysine 342mg (equivalent to ibuprofen 200mg)
Mechanism of action NSAID — inhibits COX-1 and COX-2 enzymes, reducing prostaglandin synthesis
Effective for Painful menstrual periods
Suitable for Women and girls aged 12 and over
Pack size 16 gel capsules
Strength 342mg ibuprofen lysine per capsule
UK classification P (Pharmacy medicine)
Drug class Non-steroidal anti-inflammatory drug (NSAID)
Preparation Liquid-filled gel capsule
Route of administration Oral

Specifications of Nurofen Period Pain – 16 Gel Capsules

 

What Is Nurofen Period Pain and What Is It Used For?

 

Nurofen Period Pain 16 gel capsules are an over-the-counter NSAID medicine used specifically to relieve the pain of menstrual periods (dysmenorrhoea). Each capsule contains ibuprofen lysine 342mg, equivalent to 200mg of ibuprofen. The NHS recognises ibuprofen as one of the first-line treatments for period pain, and it is widely used across the UK for this purpose. The liquid-filled capsule format is designed to support faster absorption, making it a practical choice when you want relief at the onset of cramps.

 

What Do You Need to Know Before Using Nurofen Period Pain?

 

Before taking these capsules, it's important to check whether they are appropriate for you. Do not take Nurofen Period Pain if any of the following apply:

  • You are allergic to ibuprofen, aspirin, or any other NSAID
  • You have or have had a peptic ulcer or gastrointestinal bleeding
  • You have severe heart failure, kidney disease, or liver disease
  • You are in the third trimester of pregnancy (weeks 28 onwards)
  • You are under 12 years of age
  • You have a history of asthma triggered by NSAIDs

Speak to your doctor or pharmacist before use if you have high blood pressure, a history of heart disease, inflammatory bowel disease, or if you are in the first or second trimester of pregnancy. The NHS advises caution with ibuprofen use during pregnancy.

The following medicines may interact with ibuprofen:

  • Aspirin or other NSAIDs — increased risk of side effects
  • Warfarin or other anticoagulants — increased bleeding risk
  • SSRIs (e.g. fluoxetine) — increased risk of gastrointestinal bleeding
  • Antihypertensives (e.g. ACE inhibitors, beta-blockers) — reduced effectiveness
  • Lithium — ibuprofen may increase lithium levels
  • Methotrexate — ibuprofen may increase toxicity risk

 

How Should You Use Nurofen Period Pain Gel Capsules?

 

Always take this medicine exactly as described on the label. Swallow the capsules whole with a full glass of water. Taking them with food or milk may help reduce the chance of stomach upset, though it is not always necessary.

  1. Take 2 capsules at the first sign of period pain
  2. Swallow whole with a full glass of water
  3. If pain persists, take 2 more capsules after at least 4 hours
  4. Do not take more than 6 capsules (3 doses) in any 24-hour period
  5. Do not use for more than 3 days without medical advice
Indication Age Group Dose Frequency
Menstrual pain 12–17 years 2 capsules (684mg ibuprofen lysine) Every 4 hours, max 6 capsules/24 hrs
Menstrual pain 18 years and over 2 capsules (684mg ibuprofen lysine) Every 4 hours, max 6 capsules/24 hrs

If you're also managing other health concerns alongside period pain — such as bloating or cramping that may be related to IBS — our IBS and cramps collection may offer additional support options worth exploring.

 

What Are the Possible Side Effects of Nurofen Period Pain?

 

Like all medicines, ibuprofen can cause side effects, although not everyone experiences them. The most common ones tend to affect the digestive system. If you notice anything unusual or concerning, stop taking the capsules and speak to a pharmacist or GP.

Common side effects:

  • Nausea or feeling sick
  • Indigestion or heartburn
  • Stomach pain or discomfort
  • Diarrhoea or constipation

Less common side effects:

  • Headache or dizziness
  • Skin rash or itching
  • Fluid retention (swelling of ankles or feet)
  • Raised blood pressure
  • Fatigue

Rarely, ibuprofen can cause serious reactions including gastrointestinal bleeding, allergic reactions (such as difficulty breathing or facial swelling), or kidney problems. Seek emergency medical help immediately if you experience any of these. The NHS advises that you should stop taking ibuprofen and contact a doctor if you develop signs of a serious allergic reaction.

 

How Should You Store Nurofen Period Pain?

 

Correct storage helps maintain the quality and safety of the medicine throughout its shelf life. If you're stocking up on other health essentials, our first aid collection has a range of products worth keeping at home.

  • Store below 25°C in a dry place
  • Keep away from direct sunlight and moisture
  • Keep out of reach and sight of children
  • Do not use after the expiry date printed on the pack
  • Do not store in a bathroom or near a sink
  • Do not dispose of medicines via wastewater or household waste — return unused medicines to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Nurofen Period Pain gel capsules online in the UK?

You can buy Nurofen Period Pain 16 gel capsules directly from Cured Pharmacy online for £3.99, with no prescription required. It is a P (pharmacy) medicine available over the counter to women and girls aged 12 and over. Simply add it to your basket and it will be dispatched quickly to your door.

How do ibuprofen period pain tablets work in the body?

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking COX-1 and COX-2 enzymes, which are responsible for producing prostaglandins. Prostaglandins cause the uterine contractions that lead to period cramps, so reducing them helps ease pain. The ibuprofen lysine salt in these gel capsules is designed to be absorbed quickly for faster relief.

How do I take Nurofen Period Pain capsules step by step?

Take 2 capsules at the first sign of period pain, swallowing them whole with a full glass of water. If pain continues, you may take 2 more capsules after at least 4 hours. Do not exceed 6 capsules in any 24-hour period, and do not use for more than 3 days without speaking to a pharmacist or doctor.

How quickly do Nurofen Period Pain gel capsules start working?

The liquid-filled gel capsule formulation is designed to support faster absorption of ibuprofen lysine compared to standard solid tablets. Many people begin to notice relief within 15 to 30 minutes of taking the dose, though individual response times can vary. Taking the capsules at the very first sign of cramps tends to give the best results.

What is the correct dose of Nurofen Period Pain for a 14-year-old?

For girls aged 12 and over, the dose is the same as for adults: 2 capsules (ibuprofen lysine 684mg total) taken with water, repeated every 4 hours if needed. No more than 6 capsules should be taken in any 24-hour period. If you are unsure whether this medicine is appropriate for a young person, speak to a pharmacist before use.

What are the side effects of Nurofen Period Pain capsules?

Common side effects include nausea, indigestion, stomach discomfort, and diarrhoea. Less commonly, some people experience headache, dizziness, skin rash, or fluid retention. Serious but rare reactions include gastrointestinal bleeding and severe allergic responses — stop use immediately and seek medical help if these occur.

Who should not take Nurofen Period Pain?

Do not take these capsules if you are allergic to ibuprofen, aspirin, or other NSAIDs, or if you have a peptic ulcer, severe kidney or liver disease, or serious heart failure. They are also not suitable for anyone in the third trimester of pregnancy (from week 28 onwards) or for children under 12. Always read the full patient information leaflet before use.

Can I take Nurofen Period Pain with paracetamol?

Yes, ibuprofen and paracetamol can generally be taken together as they work via different mechanisms and do not interact with each other. This combination is sometimes recommended by healthcare professionals for more effective pain relief. However, always follow the recommended doses for each medicine separately and do not exceed the stated maximum for either.

Can I take Nurofen Period Pain if I am on the contraceptive pill?

There is no known clinically significant interaction between ibuprofen and combined oral contraceptives or progestogen-only pills. Short-term use of ibuprofen period pain tablets at the recommended dose is generally considered safe alongside hormonal contraception. If you have any concerns, your pharmacist can advise you based on your full medication history.

What medicines interact with Nurofen Period Pain?

Ibuprofen can interact with several medicines, including aspirin, warfarin, SSRIs (such as fluoxetine), ACE inhibitors, beta-blockers, lithium, and methotrexate. These interactions can increase the risk of side effects such as bleeding, reduced blood pressure control, or increased drug toxicity. Always tell your pharmacist about all medicines you are taking before starting ibuprofen.

Is Nurofen Period Pain safe to take during pregnancy?

Nurofen Period Pain should not be taken during the third trimester of pregnancy (from week 28 onwards) as it may harm the unborn baby. Use in the first and second trimesters should only be considered on medical advice, as the NHS recommends avoiding ibuprofen in pregnancy where possible. Paracetamol is generally considered the preferred pain relief option during pregnancy.

What happens if I take too many Nurofen Period Pain capsules?

Taking more than the recommended dose of ibuprofen can cause serious harm, including stomach bleeding, kidney damage, and in severe cases, liver problems. If you or someone else has taken too many capsules, contact NHS 111 or go to your nearest A&E immediately. Always keep medicines out of reach of children to prevent accidental ingestion.

What are the alternatives to Nurofen Period Pain for menstrual cramps?

Alternatives include other NSAIDs such as naproxen, or paracetamol for those who cannot take ibuprofen. Heat therapy (such as a hot water bottle applied to the lower abdomen) is also recommended by the NHS as a non-medicine option. You can explore our broader women's health range for additional support products.

How long can I keep taking Nurofen Period Pain each month?

Nurofen Period Pain is intended for short-term use only — no more than 3 consecutive days per episode without medical advice. If your period pain is severe, recurring, or not responding to over-the-counter treatment, speak to your GP as this may indicate an underlying condition such as endometriosis. Long-term regular use of NSAIDs without medical supervision is not recommended.

Are there any lifestyle tips to use alongside ibuprofen period pain tablets?

The NHS suggests that regular exercise, applying heat to the lower abdomen, and relaxation techniques can help reduce the severity of period pain alongside medication. Reducing caffeine and alcohol intake during your period may also help. If you're looking to support your overall wellbeing, our vitamins and supplements collection includes options such as magnesium, which some research suggests may help with muscle cramps.

How Should You Use Nurofen Period Pain Gel Capsules?

Swallow the capsules whole — do not chew, crush, or open them. Taking them with a full glass of water helps the capsule reach your stomach quickly and reduces the chance of irritation.

What Is the Correct Dose of Nurofen Period Pain?

The dose is the same for all eligible users aged 12 and over. Always use the lowest effective dose for the shortest time necessary to control your symptoms. Never exceed the maximum daily dose stated below.

When Is the Best Time to Use Nurofen Period Pain?

Take the capsules as soon as you notice the first signs of menstrual cramping — don't wait until the pain becomes severe. Early intervention tends to give better results because ibuprofen works by reducing prostaglandin production, which is most effective when levels are still rising rather than already peaked.

If you know from experience that your period pain tends to start on a particular day of your cycle, you may find it helpful to have the capsules ready in advance so you can act quickly. Taking them with or after a light snack can also help if you have a sensitive stomach.

How Long Can You Use Nurofen Period Pain For?

These capsules are intended for short-term use only. Do not use for more than 3 consecutive days per menstrual episode without seeking advice from a pharmacist or GP. If your period pain is not adequately controlled with over-the-counter ibuprofen, or if it is getting progressively worse over time, this could indicate an underlying condition such as endometriosis or fibroids — both of which warrant a medical assessment.

Regular long-term use of NSAIDs without medical supervision carries risks including gastrointestinal problems and kidney strain, so it is important not to rely on them beyond the recommended duration.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Nurofen Period Pain?

Like all NSAIDs, ibuprofen can cause side effects in some people, though many users tolerate it well when taken at the recommended dose for a short period. The most frequently reported side effects relate to the digestive system, particularly if the capsules are taken on an empty stomach.

  • Nausea or feeling sick
  • Indigestion or heartburn
  • Stomach pain or discomfort
  • Diarrhoea
  • Constipation
  • Bloating or wind

What Are the Less Common Side Effects of Nurofen Period Pain?

Some people experience side effects that are less frequent but still worth being aware of. These tend to occur more often with higher doses or prolonged use, which is why sticking to the recommended dose and duration is so important.

  • Headache or dizziness
  • Skin rash or itching
  • Fluid retention (swelling of the ankles or feet)
  • Raised blood pressure
  • Fatigue or drowsiness
  • Tinnitus (ringing in the ears)

What Are the Serious Side Effects of Nurofen Period Pain?

Serious side effects are rare but can occur. You should stop taking the capsules immediately and seek urgent medical attention if you experience any of the following:

  • Signs of gastrointestinal bleeding — such as vomiting blood, or black/tarry stools
  • Severe allergic reaction — including facial swelling, difficulty breathing, or a widespread skin rash
  • Chest pain, shortness of breath, or sudden weakness (possible signs of a cardiovascular event)
  • Significant reduction in urine output or swelling, which may indicate kidney problems
  • Severe skin reactions such as blistering or peeling

What Should You Do If You Experience Side Effects of Nurofen Period Pain?

If you develop mild digestive side effects, try taking the capsules with food or milk to reduce stomach irritation. For more persistent or concerning symptoms, stop taking the medicine and speak to your pharmacist or GP as soon as possible. You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk — this helps improve medicine safety for everyone.

If you accidentally take too many capsules, contact NHS 111 immediately or go to your nearest A&E. Do not wait for symptoms to appear, as ibuprofen overdose can cause serious harm even before you feel unwell.

Can Nurofen Period Pain Interact With Other Medicines?

Yes. Ibuprofen has a number of clinically significant drug interactions that you should be aware of before taking these capsules. Always inform your pharmacist of all medicines you are currently taking — including prescription medicines, other over-the-counter products, and herbal remedies.

  • Aspirin or other NSAIDs — increased risk of gastrointestinal side effects
  • Warfarin or other anticoagulants — increased risk of bleeding
  • SSRIs (e.g. fluoxetine, sertraline) — increased risk of gastrointestinal bleeding
  • ACE inhibitors or beta-blockers — ibuprofen may reduce their blood pressure-lowering effect
  • Lithium — ibuprofen may raise lithium plasma levels, increasing toxicity risk
  • Methotrexate — ibuprofen may increase methotrexate toxicity
  • Diuretics — ibuprofen may reduce their effectiveness and increase kidney strain

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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