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Numark Night Cold and Flu oral solution 200ml (brand may vary)

Numark Night Cold and Flu oral solution 200ml (brand may vary)

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  • ✔️ Relieves fever, aches, and runny nose overnight
  • ✔️ Contains paracetamol 1000mg per dose for effective pain relief
  • ✔️ Diphenhydramine promotes sleep while relieving cold symptoms
  • ✔️ Single bedtime dose covers symptoms through the night
  • ✔️ Liquid format for easy swallowing when feeling unwell

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What Is Night Cold and Flu Relief Oral Solution?

 

When a cold or flu hits at night, it can feel relentless. The blocked nose, the aching limbs, the fever that won't settle — all of it conspiring to rob you of the sleep you desperately need to recover. Night cold and flu relief in liquid form is designed specifically for those hours, combining symptom relief with a gentle sedative effect so your body can actually rest. Numark Night Cold and Flu Oral Solution 200ml does exactly that, offering a measured, easy-to-swallow dose you take at bedtime. You can browse the full range of cold and flu remedies at Cured Pharmacy if you want to compare your options.

This product is classified as a pharmacy (P) medicine in the UK, meaning it's available over the counter without a prescription. It's a practical choice for adults who want targeted overnight relief without the need for multiple separate products.

 

How Does Numark Night Cold and Flu Oral Solution Work?

 

The solution works through two active ingredients that complement each other well. Paracetamol tackles the fever and the generalised aches and pains that come with cold and flu. Diphenhydramine hydrochloride — a first-generation antihistamine — addresses the runny nose and sneezing while also producing a sedative effect that helps you drift off. Together, they target the most disruptive nighttime symptoms in one dose.

  • Paracetamol inhibits prostaglandin synthesis in the central nervous system, reducing fever and pain signals.
  • Diphenhydramine blocks H1 histamine receptors, reducing nasal secretions and sneezing.
  • The antihistamine's sedative properties cross the blood-brain barrier, promoting drowsiness and supporting sleep onset.
  • The oral liquid format allows for relatively rapid absorption compared to solid-dose tablets.

 

Who Should Use Numark Night Cold and Flu Oral Solution?

 

This product is intended for adults and young people aged 16 and over who are experiencing nighttime cold or flu symptoms. It's particularly useful if you're struggling to sleep due to a combination of fever, aches, and nasal symptoms. That said, it isn't suitable for everyone — always read the label carefully before use.

  • Adults aged 16 and over with cold or flu symptoms disrupting sleep
  • People who prefer a liquid formulation over tablets or capsules
  • Those who want a single product addressing multiple symptoms at once
  • Individuals without contraindications to paracetamol or diphenhydramine

 

How Does Numark Night Cold and Flu Compare to Daytime Cold Remedies?

 

Feature Numark Night Cold and Flu Oral Solution Typical Daytime Cold Remedy
Active ingredients Paracetamol + Diphenhydramine HCl Paracetamol + Decongestant (e.g. phenylephrine)
Sedative effect Yes — promotes sleep No — designed to keep you alert
Suitable for driving No Often yes (check label)
Dosing frequency Once at bedtime only Every 4–6 hours during the day

 

Is Numark Night Cold and Flu Oral Solution Stored Correctly?

 

Store this product below 25°C, away from direct sunlight and out of reach of children. Do not use after the expiry date printed on the bottle. Once opened, check the product label for any in-use storage guidance. If you're also managing other symptoms like throat discomfort or ear pain, you might find our ear, nose and throat range helpful alongside your cold and flu treatment.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Numark Night Cold and Flu Oral Solution 200ml specifications
Treatment category Cold and flu symptom relief
Mechanism of action Analgesic/antipyretic (paracetamol) + H1 antihistamine/sedative (diphenhydramine HCl)
Effective for Fever, aches and pains, runny nose, sneezing, sleeplessness due to cold and flu
Suitable for Adults and young people aged 16 and over
Active ingredients Paracetamol 1000mg per 20ml dose; Diphenhydramine hydrochloride 25mg per 20ml dose
Pack size 200ml
UK classification Pharmacy (P) medicine
Drug class Analgesic / First-generation antihistamine
Preparation Oral solution
Route of administration Oral

Specifications of Numark Night Cold and Flu Oral Solution 200ml

 

What Is Numark Night Cold and Flu Oral Solution and What Is It Used For?

 

Numark Night Cold and Flu Oral Solution is an over-the-counter liquid medicine used to relieve the symptoms of colds and flu at night. It contains two active ingredients: paracetamol (1000mg per 20ml dose) and diphenhydramine hydrochloride (25mg per 20ml dose). Paracetamol is a well-established analgesic and antipyretic — it reduces fever and relieves mild to moderate pain such as headaches and muscle aches. Diphenhydramine hydrochloride is a first-generation antihistamine that helps dry up a runny nose and relieve sneezing, while also causing drowsiness that can help you sleep through the night.

It is intended for short-term use only and should be taken as a single dose at bedtime. The NHS advises that most colds clear up within 7 to 10 days, and symptomatic relief medicines like this one can help you manage discomfort during that period.

 

What Do You Need to Know Before Using Numark Night Cold and Flu Oral Solution?

 

Before taking this product, it's important to check whether it's appropriate for you. Do not take it if any of the following apply:

  • You are allergic to paracetamol, diphenhydramine, or any other ingredient in the product
  • You are under 12 years of age
  • You have severe liver or kidney disease
  • You have glaucoma (raised pressure in the eye)
  • You have difficulty urinating due to an enlarged prostate
  • You are taking monoamine oxidase inhibitors (MAOIs) or have taken them within the last 14 days
  • You are pregnant or breastfeeding — speak to your doctor or pharmacist first
  • You regularly drink large amounts of alcohol

Be aware of the following potential drug interactions:

  • Other paracetamol-containing products — risk of accidental overdose
  • Sedatives, sleeping tablets, or anxiolytics — increased drowsiness
  • Other antihistamines — additive sedative and anticholinergic effects
  • Warfarin — prolonged regular use of paracetamol may enhance anticoagulant effect
  • Metoclopramide or domperidone — may affect paracetamol absorption rate

 

How Should You Use Numark Night Cold and Flu Oral Solution?

 

Always use this product exactly as directed on the label. Take it at bedtime only — this is not a daytime medicine. Because diphenhydramine causes drowsiness, you should not drive, operate machinery, or drink alcohol after taking it. If you're looking for daytime symptom support, our pain relief range includes options suitable for use during the day.

  1. Shake the bottle gently before use.
  2. Measure 20ml using the measuring cup or spoon provided.
  3. Take the dose orally at bedtime.
  4. Do not take more than one dose in any 24-hour period.
  5. Do not take for more than 3 consecutive nights without medical advice.
Age Group Dose Frequency Maximum duration
Adults and young people aged 16+ 20ml Once at bedtime 3 nights
Children aged 12–15 Only under medical supervision As directed by doctor As directed
Children under 12 Not suitable

 

What Are the Possible Side Effects of Numark Night Cold and Flu Oral Solution?

 

Like all medicines, this product can cause side effects, although not everyone experiences them. The diphenhydramine component is responsible for most of the side effects listed below. If you experience anything severe or unexpected, stop taking the product and seek medical advice.

Common side effects:

  • Drowsiness (this is expected and is part of the nighttime action)
  • Dry mouth
  • Dizziness
  • Blurred vision
  • Difficulty passing urine

Less common side effects:

  • Nausea or stomach upset
  • Headache
  • Paradoxical excitability (particularly in older adults or children — another reason this product is not for under-12s)
  • Skin rash or allergic reaction — stop use immediately if this occurs
  • Palpitations

Paracetamol is generally very well tolerated at recommended doses. However, exceeding the stated dose can cause serious liver damage. Never take additional paracetamol-containing products alongside this solution.

 

How Should You Store Numark Night Cold and Flu Oral Solution?

 

Correct storage helps maintain the product's safety and effectiveness. If you're building a home medicine cabinet, you might also want to explore our first aid range for other essentials.

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Keep the bottle tightly closed when not in use
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the label
  • Do not dispose of medicines via wastewater or household waste — return unused medicine to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Numark Night Cold and Flu oral solution online in the UK?

You can buy Numark Night Cold and Flu Oral Solution 200ml directly from Cured Pharmacy online for £6.29. It is an over-the-counter medicine, so no prescription is needed. Simply add it to your basket and it will be dispatched to your door.

How does Numark Night Cold and Flu oral solution work in the body?

The solution contains paracetamol, which reduces fever and relieves aches by inhibiting prostaglandin synthesis in the central nervous system. Diphenhydramine hydrochloride blocks H1 histamine receptors to dry up a runny nose and relieve sneezing, while its sedative properties help you fall asleep. Together, these two ingredients address the most disruptive nighttime cold and flu symptoms in a single dose.

How do I use Numark Night Cold and Flu oral solution step by step?

Using this product correctly is straightforward. Follow these steps:

  1. Shake the bottle gently before measuring your dose.
  2. Measure exactly 20ml using the measuring cup provided.
  3. Take the dose orally at bedtime only — do not take during the day.
  4. Do not take a second dose within 24 hours.
What is the correct dose of Numark Night Cold and Flu oral solution for adults?

The recommended dose for adults and young people aged 16 and over is 20ml taken once at bedtime. This delivers 1000mg of paracetamol and 25mg of diphenhydramine hydrochloride per dose. Do not take more than one dose in any 24-hour period.

When is the best time to take Numark Night Cold and Flu oral solution?

This product should only be taken at bedtime — it is specifically formulated for nighttime use. Taking it at any other time of day is not appropriate because diphenhydramine causes significant drowsiness, which would make driving or operating machinery dangerous. Plan to take it shortly before you intend to sleep.

Is Numark Night Cold and Flu oral solution suitable for children?

This product is not suitable for children under 12 years of age. Children aged 12 to 15 may only use it under medical supervision. For children's cold and flu products, speak to your pharmacist, or explore our baby and toddler range for age-appropriate options.

Can I take Numark Night Cold and Flu oral solution if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, you should speak to your doctor or pharmacist before taking this product. While paracetamol is generally considered the analgesic of choice during pregnancy at the lowest effective dose for the shortest time, diphenhydramine's suitability during pregnancy and breastfeeding requires individual medical assessment. Do not self-medicate without professional guidance.

What are the side effects of Numark Night Cold and Flu oral solution and how do I manage them?

The most common side effects include drowsiness, dry mouth, dizziness, and blurred vision — these are largely expected due to the diphenhydramine component and are generally mild. Staying well hydrated can help with dry mouth. If you experience a skin rash, difficulty breathing, or any sign of an allergic reaction, stop taking the product immediately and seek medical attention.

Can I drink alcohol while taking Numark Night Cold and Flu oral solution?

No — you should not drink alcohol while taking this product. Alcohol significantly increases the sedative effects of diphenhydramine, which can be dangerous. It can also increase the risk of liver damage when combined with paracetamol, particularly if you drink regularly or in large amounts. Avoid alcohol entirely on any night you take this medicine.

What medicines interact with Numark Night Cold and Flu oral solution?

Several medicines can interact with this product. Key interactions include:

  • Other paracetamol-containing products — risk of overdose
  • MAOIs — serious and potentially dangerous interaction
  • Sedatives, sleeping tablets, or antihistamines — increased drowsiness
  • Warfarin — paracetamol may enhance anticoagulant effect with prolonged use

Always tell your pharmacist about all medicines you are taking before starting this product.

How long can I use Numark Night Cold and Flu oral solution for?

This product is intended for short-term use only. Do not use it for more than 3 consecutive nights without speaking to a doctor or pharmacist. If your symptoms persist beyond this period, worsen, or are accompanied by a high fever that doesn't respond to treatment, seek medical advice promptly.

What happens if I accidentally take too much Numark Night Cold and Flu oral solution?

If you take more than the recommended dose, seek medical attention immediately — even if you feel well. Paracetamol overdose can cause serious liver damage, and symptoms may not appear for several hours. Go to your nearest A&E or call 999. Always keep the product packaging with you so medical staff can see what you have taken.

What are the alternatives to Numark Night Cold and Flu oral solution?

There are several alternative nighttime cold and flu products available in the UK, including other paracetamol and diphenhydramine combination products from different brands. You can explore the full cold and flu range at Cured Pharmacy to compare options. Your pharmacist can help you choose the most appropriate product based on your specific symptoms and medical history.

Can I take Numark Night Cold and Flu oral solution if I have liver or kidney problems?

If you have severe liver or kidney disease, you should not take this product without first speaking to your doctor. Paracetamol is processed by the liver, and impaired liver function can increase the risk of toxicity even at standard doses. Your GP or pharmacist can advise on a safe alternative if needed.

What does the latest research say about diphenhydramine for cold and flu symptoms?

First-generation antihistamines like diphenhydramine have been used for decades to manage cold symptoms such as runny nose and sneezing, and their efficacy for these indications is well established in clinical literature. The NHS notes that antihistamines can help relieve some cold symptoms, though they are most effective for the nasal symptoms rather than fever or pain. Paracetamol remains one of the most widely recommended analgesics and antipyretics for cold and flu management in the UK.

How Should You Use Numark Night Cold and Flu Oral Solution?

This product is for oral use only and should be taken at bedtime. Because it contains diphenhydramine, which causes drowsiness, you must not take it during the day, drive, or operate machinery after taking your dose. Always use the measuring cup or spoon provided — do not estimate your dose using a household spoon, as this can lead to inaccurate measurement.

What Is the Correct Dose of Numark Night Cold and Flu Oral Solution?

The dose varies by age group. Always follow the guidance below and never exceed the stated dose. If you are unsure whether this product is appropriate for you, speak to your pharmacist before use.

When Is the Best Time to Use Numark Night Cold and Flu Oral Solution?

Take this product at bedtime only — ideally shortly before you intend to sleep. The diphenhydramine component begins to produce its sedative effect within 30 to 60 minutes of ingestion, so timing your dose appropriately means you can benefit from both the symptom relief and the sleep-promoting effect. Do not take it earlier in the evening if you still need to drive or carry out tasks requiring concentration.

How Long Can You Use Numark Night Cold and Flu Oral Solution For?

This product is intended for short-term use only. Do not take it for more than 3 consecutive nights without seeking advice from a doctor or pharmacist. If your cold or flu symptoms persist beyond this period, worsen significantly, or are accompanied by a high or persistent fever, you should seek medical attention rather than continuing to self-treat. Prolonged use of diphenhydramine can lead to tolerance of its sedative effects and is not recommended.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Numark Night Cold and Flu Oral Solution?

The most frequently reported side effects of this product are related to the diphenhydramine hydrochloride component. These effects are largely predictable given the antihistamine's mechanism of action and are generally mild. Drowsiness, in particular, is an intended effect when the product is taken at bedtime.

  • Drowsiness and sedation
  • Dry mouth
  • Dizziness
  • Blurred vision
  • Difficulty passing urine (urinary retention)

What Are the Less Common Side Effects of Numark Night Cold and Flu Oral Solution?

Some people may experience less common side effects. These are not experienced by everyone but are worth being aware of before you start taking the product. If any of the following persist or concern you, stop use and speak to your pharmacist or GP.

  • Nausea or stomach discomfort
  • Headache
  • Palpitations or a faster-than-normal heartbeat
  • Paradoxical excitability or restlessness (more likely in older adults)
  • Skin rash or itching
  • Constipation

What Are the Serious Side Effects of Numark Night Cold and Flu Oral Solution?

Serious side effects are rare when this product is used as directed, but they can occur. Paracetamol overdose — whether accidental or intentional — can cause severe and potentially fatal liver damage. Symptoms of overdose may not appear immediately, which is why it is critical to seek emergency medical help even if you feel well after taking too much. Signs of a serious allergic reaction (anaphylaxis) include swelling of the face, lips, or throat, difficulty breathing, and a sudden drop in blood pressure. If you experience any of these, call 999 immediately.

What Should You Do If You Experience Side Effects of Numark Night Cold and Flu Oral Solution?

For mild side effects such as dry mouth or morning drowsiness, these usually resolve on their own and do not require treatment. Staying well hydrated can help with dry mouth. If you experience a skin rash, difficulty breathing, or any sign of an allergic reaction, stop taking the product immediately and seek urgent medical attention. For suspected overdose, go to your nearest A&E or call 999 without delay — always take the product packaging with you.

Can Numark Night Cold and Flu Oral Solution Interact With Other Medicines?

Yes. This product has several clinically significant interactions. Taking it alongside other paracetamol-containing medicines — including many other cold and flu remedies — can lead to accidental overdose. Combining it with sedatives, sleeping tablets, or other antihistamines increases the risk of excessive drowsiness. Monoamine oxidase inhibitors (MAOIs) must not be taken within 14 days of this product. If you are taking warfarin, prolonged use of paracetamol may enhance its anticoagulant effect. Always inform your pharmacist of all medicines, supplements, and herbal remedies you are currently taking.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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