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Nicorette Nasal Spray 10ml

Nicorette Nasal Spray 10ml

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  • ✔️ Delivers nicotine in minutes via fast nasal absorption
  • ✔️ Reduces sudden, intense cigarette cravings on demand
  • ✔️ Each actuation provides 500 micrograms of nicotine
  • ✔️ Suitable for heavy smokers needing rapid craving relief
  • ✔️ Can be combined with patches for greater quit success

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What Is Nicorette Nasal Spray and How Can It Help You Quit Smoking?

 

Quitting smoking is one of the most significant things you can do for your long-term health — but it is rarely easy. Cravings can hit suddenly and intensely, and that is exactly where Nicorette nasal spray steps in. This 10ml nasal spray delivers nicotine rapidly through the lining of your nose, helping to take the edge off cravings almost as soon as they strike. It is one of the fastest-acting forms of nicotine replacement therapy (NRT) available without a prescription in the UK. You can explore the full range of smoking cessation products at Cured Pharmacy to find the right combination for your quit journey.

Nicotine dependence is a recognised medical condition, and the NHS recommends NRT as a first-line treatment to support people who want to stop smoking. Using NRT roughly doubles your chances of quitting successfully compared with willpower alone. The nasal spray format is particularly useful for people who need fast relief from sudden, intense cravings.

 

How Does Nicorette Nasal Spray Work to Reduce Cravings?

 

The spray works by replacing some of the nicotine your body was getting from cigarettes, without the thousands of harmful chemicals found in tobacco smoke. Here is how it works step by step:

  • You spray nicotine solution into one or both nostrils.
  • Nicotine is absorbed rapidly through the nasal mucosa (the lining of your nose) into the bloodstream.
  • Blood nicotine levels rise quickly, helping to ease withdrawal symptoms such as irritability, anxiety, and intense cravings.
  • Over time, you gradually reduce the number of doses per day, weaning your body off nicotine dependence.

Each actuation delivers 500 micrograms of nicotine. One dose consists of one spray into each nostril. The speed of absorption is what sets this format apart from patches or gum, making it particularly suited to managing sudden, unpredictable cravings.

 

Who Should Use Nicorette Nasal Spray — Is It Right for You?

 

This product is designed for adults aged 18 and over who are actively trying to stop smoking. It is especially well suited to people who:

  • Experience sudden, intense cravings that need fast relief
  • Have not had success with slower-acting NRT formats such as patches
  • Smoke heavily (more than 20 cigarettes per day)
  • Want a discreet, portable option they can use anywhere

It is not suitable for non-smokers, people under 18, or those who have never smoked. If you are pregnant, breastfeeding, or have a history of heart disease, stroke, or severe kidney or liver problems, you should speak to your GP or pharmacist before starting treatment.

 

How Does Nicorette Nasal Spray Compare to Other NRT Options?

 

Feature Nicorette Nasal Spray Nicotine Patch
Speed of action Fast (minutes) Slow (hours)
Best for Sudden, intense cravings Background nicotine maintenance
Dosing control On-demand, flexible Fixed, continuous release
Discreet use Moderate High (worn under clothing)

 

How Should You Store Nicorette Nasal Spray and Is It Clinically Suitable for You?

 

Store your Nicorette nasal spray below 25°C, away from direct sunlight and out of reach of children. Do not freeze the product. Once opened, check the expiry date on the packaging and do not use it beyond that date. If you are managing other health conditions alongside your quit attempt — for example, if you are also monitoring blood glucose levels or managing a cardiovascular condition — it is worth speaking to your pharmacist before starting. You can also browse vitamins and supplements at Cured Pharmacy to support your overall wellbeing during the quitting process.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Nicorette Nasal Spray 10ml specifications
Treatment category Nicotine Replacement Therapy (NRT) / Smoking Cessation
Active ingredient Nicotine 500 micrograms per actuation
Mechanism of action Replaces nicotine from cigarettes; absorbed via nasal mucosa to reduce withdrawal symptoms
Suitable for Adults aged 18 and over who smoke and wish to quit
Pack size 10ml
Strength 500 micrograms nicotine per spray
UK classification General Sale / Pharmacy (P) medicine
Drug class Nicotinic receptor agonist
Preparation Aqueous nasal spray solution
Route of administration Intranasal

Specifications of Nicorette Nasal Spray 10ml

 

What Is Nicorette Nasal Spray and What Is It Used For?

 

Nicorette Nasal Spray 10ml is a nicotine replacement therapy used to help adults stop smoking. It contains nicotine as its active ingredient, delivered as a fine mist into the nostrils. It is used to relieve and prevent the withdrawal symptoms and cravings that occur when you stop smoking, including irritability, difficulty concentrating, increased appetite, and restlessness. The NHS recommends NRT as an effective and safe way to support smoking cessation, and this nasal spray format is one of the fastest-acting options available over the counter.

 

What Do You Need to Know Before Using Nicorette Nasal Spray?

 

Do not use this product if any of the following apply to you:

  • You are under 18 years of age
  • You are a non-smoker or an occasional smoker
  • You have a known hypersensitivity (allergy) to nicotine or any other ingredient in the spray
  • You have severe or worsening cardiovascular disease (unless advised by a doctor)
  • You have chronic nasal disorders such as severe rhinitis or nasal polyps

Speak to your doctor or pharmacist before use if you:

  • Are pregnant or breastfeeding — nicotine can harm a developing baby
  • Have recently had a heart attack or stroke
  • Have uncontrolled hypertension (high blood pressure)
  • Have diabetes — monitor blood glucose more closely when starting NRT
  • Have kidney or liver impairment
  • Have a history of seizures or epilepsy

Regarding drug interactions, no clinically significant interactions have been identified at therapeutic NRT doses. However, stopping smoking itself can affect the metabolism of certain medicines, including theophylline, clozapine, and warfarin. If you take any of these, inform your prescriber when you quit.

  • Theophylline — plasma levels may rise when you stop smoking
  • Clozapine — dose adjustment may be needed
  • Warfarin — INR monitoring may be required

 

How Should You Use Nicorette Nasal Spray Correctly?

 

Always use this product exactly as described in the patient information leaflet. Before first use, prime the pump by pressing it several times until a fine mist appears.

  1. Blow your nose gently if needed before use.
  2. Tilt your head slightly forward — do not tilt it back.
  3. Insert the nozzle into one nostril, pointing it away from the nasal septum.
  4. Press the pump firmly once to release one spray.
  5. Do not sniff, swallow, or inhale during or immediately after spraying.
  6. Repeat in the other nostril to complete one full dose.
  7. Use one dose (two sprays) when you feel the urge to smoke.
Indication Age Group Dose Maximum Daily Dose
Smoking cessation / craving relief Adults 18+ 1 spray per nostril (1 dose) 32 doses (64 sprays) per day
Not recommended Under 18

If you are also using other smoking cessation products from our range, speak to your pharmacist to ensure you are not exceeding a safe total nicotine intake.

 

What Are the Possible Side Effects of Nicorette Nasal Spray?

 

Like all medicines, Nicorette Nasal Spray can cause side effects, although not everyone gets them. Most side effects are mild and tend to improve after the first week of use as your nose adjusts.

Common side effects (may affect more than 1 in 10 people):

  • Nasal irritation or burning sensation
  • Sneezing
  • Runny or watery nose
  • Watery eyes
  • Throat irritation
  • Coughing

Less common side effects (may affect up to 1 in 10 people):

  • Headache
  • Nausea or stomach upset
  • Palpitations (awareness of your heartbeat)
  • Dizziness
  • Nasal congestion
  • Skin flushing

Stop using the spray and seek medical advice immediately if you experience chest pain, irregular heartbeat, or signs of an allergic reaction such as swelling of the face, lips, or throat. If you experience persistent nausea or dizziness, you may be using more doses than you need — try reducing the frequency. You can also speak to our pharmacist team for guidance. If you are managing other symptoms alongside your quit attempt, our cold and flu range may help with any nasal congestion that develops separately.

 

How Should You Store Nicorette Nasal Spray Safely?

 

  • Store below 25°C in a cool, dry place
  • Do not freeze
  • Keep away from direct sunlight and heat sources
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the label
  • Do not dispose of medicines via wastewater or household waste — return unused product to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Nicorette Nasal Spray online in the UK?

You can buy Nicorette Nasal Spray 10ml directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for £27.99. It is available without a prescription as an over-the-counter nicotine replacement therapy. Browse our full smoking cessation range for additional NRT options to support your quit plan.

How does Nicorette Nasal Spray work in the body?

Nicorette Nasal Spray delivers nicotine through the nasal mucosa directly into the bloodstream, helping to reduce cravings and withdrawal symptoms associated with stopping smoking. It acts faster than many other NRT formats because absorption via the nasal lining is rapid. This makes it particularly useful for managing sudden, intense urges to smoke.

How do I use Nicorette Nasal Spray step by step?

Tilt your head slightly forward, insert the nozzle into one nostril, and press the pump once firmly. Do not sniff, swallow, or inhale during or immediately after spraying. Repeat in the other nostril to complete one full dose, and use as needed when you feel the urge to smoke.

What is the recommended dose of Nicorette Nasal Spray per day?

The usual dose is one spray into each nostril (counted as one dose) when you feel the urge to smoke. The maximum is 32 doses (64 sprays) per day, though most people use far fewer. Always follow the instructions in the patient information leaflet and reduce your dose gradually over time.

What are the side effects of Nicorette Nasal Spray and how do I manage them?

The most common side effects are nasal irritation, sneezing, runny nose, and watery eyes — these typically improve after the first week as your nose adjusts. If you experience persistent nausea or dizziness, you may be using more doses than necessary, so try reducing the frequency. Speak to your pharmacist if side effects are troublesome or do not settle.

Who is eligible to use Nicorette Nasal Spray?

Nicorette Nasal Spray is suitable for adults aged 18 and over who are actively trying to quit smoking. It is not suitable for non-smokers, people under 18, or those with certain nasal conditions such as severe rhinitis or nasal polyps. People who are pregnant, breastfeeding, or have a history of cardiovascular disease should consult a doctor or pharmacist before use.

Can I use Nicorette Nasal Spray if I am pregnant?

Stopping smoking is the safest option during pregnancy, and NRT is generally considered preferable to continuing to smoke. However, nicotine can affect a developing baby, so you should always speak to your GP or midwife before using any NRT product during pregnancy. They can help you weigh up the risks and benefits and recommend the most appropriate form of support.

What happens if I miss a dose of Nicorette Nasal Spray?

Nicorette Nasal Spray is used on demand rather than on a fixed schedule, so there is no traditional "missed dose" in the same way as a daily tablet. If you feel a craving and have not used the spray, use it as soon as you need it. Do not use extra doses to compensate — simply continue with your normal pattern of use.

How long should I use Nicorette Nasal Spray for?

The recommended treatment duration is up to three months, during which you gradually reduce the number of doses you use each day. After three months, you should aim to stop using the spray entirely or switch to a lower-strength NRT format. Use beyond six months should be discussed with your pharmacist or GP.

Can I use Nicorette Nasal Spray alongside other NRT products?

Yes — combination NRT (for example, using a patch for background nicotine alongside the nasal spray for sudden cravings) is recommended by the NHS and can be more effective than using a single product alone. Always speak to your pharmacist to ensure your combined nicotine intake remains within safe limits. Do not use two fast-acting NRT products simultaneously without professional guidance.

What are the alternatives to Nicorette Nasal Spray for quitting smoking?

There are several NRT alternatives available, including nicotine patches, gum, lozenges, inhalators, and mouth spray. Prescription options such as varenicline (Champix) and bupropion are also available via your GP. You can explore the full range of smoking cessation aids at Cured Pharmacy to find the format that suits you best.

Is Nicorette Nasal Spray safe to use with other medicines?

No clinically significant drug interactions have been identified with nicotine replacement therapy at therapeutic doses. However, stopping smoking itself can affect how your body processes certain medicines, including theophylline, clozapine, and warfarin. If you take any of these, inform your prescriber or pharmacist when you begin your quit attempt so they can monitor you appropriately.

Does Nicorette Nasal Spray cause dependence?

Nicotine nasal spray can cause nicotine dependence, though this is generally considered less harmful than dependence on cigarettes. The risk is managed by gradually reducing your dose over the treatment period rather than stopping abruptly. If you find it difficult to reduce your use, speak to your pharmacist or a stop-smoking adviser for support.

What does the latest research say about nicotine nasal spray for quitting smoking?

Clinical evidence consistently supports nicotine replacement therapy as an effective aid to smoking cessation, with NRT roughly doubling quit rates compared to placebo. Fast-acting formats such as nasal spray are particularly valued for managing acute cravings. The NHS and NICE both recommend NRT as a first-line treatment for adults who want to stop smoking.

How should I store Nicorette Nasal Spray at home?

Store Nicorette Nasal Spray below 25°C in a cool, dry place away from direct sunlight and heat sources. Do not freeze the product, and always keep it out of the reach and sight of children. Check the expiry date on the packaging before each use and return any unused medicine to your pharmacy for safe disposal.

How Should You Use Nicorette Nasal Spray?

Using Nicorette Nasal Spray correctly is important to get the most benefit and to minimise side effects. Before your very first use, prime the pump by pressing it several times until a fine mist appears — this ensures the correct dose is delivered from the outset.

If you experience significant nasal irritation in the first few days, this is normal and usually settles as your nasal lining adjusts. Try not to use the spray more frequently than needed — use it only when you feel a genuine urge to smoke.

What Is the Correct Dose of Nicorette Nasal Spray?

The dose you need will depend on how heavily you smoke and how intense your cravings are. Most people start by using one dose (one spray per nostril) whenever they feel the urge to smoke, then gradually reduce the number of doses over the treatment period. Never exceed the maximum daily dose.

If you are combining the nasal spray with a nicotine patch (combination NRT), your pharmacist can advise on the appropriate total nicotine intake to keep you safe and comfortable.

When Is the Best Time to Use Nicorette Nasal Spray?

Use the spray as soon as you feel the urge to smoke — do not wait until the craving becomes overwhelming. The nasal spray is designed for on-demand use, so there is no fixed schedule. Many people find it helpful to use it at the times they would normally have smoked, such as after meals, during work breaks, or when feeling stressed.

If you are using a nicotine patch alongside the spray, apply the patch first thing in the morning and use the spray as a top-up throughout the day whenever cravings arise. Planning ahead for high-risk moments — social situations, alcohol, or stressful events — can help you use the spray proactively rather than reactively.

How Long Can You Use Nicorette Nasal Spray For?

The recommended treatment course is up to three months. During this time, you should aim to gradually reduce the number of doses you use each day, working towards stopping the spray entirely. Most people find they naturally need fewer doses as their quit attempt progresses and cravings become less frequent and intense.

If you still feel you need the spray after three months, speak to your pharmacist or GP. Use beyond six months is not generally recommended without professional guidance. The goal is always to become free from nicotine dependence altogether, not simply to replace one source of nicotine with another long term.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Nicorette Nasal Spray?

Most people experience some nasal side effects when they first start using Nicorette Nasal Spray, particularly in the first week. These are caused by the nicotine solution coming into contact with the sensitive lining of your nose and are not usually a sign that anything is seriously wrong.

  • Nasal irritation or burning sensation inside the nose
  • Sneezing — often immediately after use
  • Runny or watery nose (rhinorrhoea)
  • Watery eyes
  • Throat irritation or mild soreness
  • Coughing

These effects typically improve significantly after the first week as your nasal mucosa adapts to the spray. If they remain severe or do not settle, speak to your pharmacist.

What Are the Less Common Side Effects of Nicorette Nasal Spray?

Some people experience side effects that are related to nicotine absorption rather than the nasal route of delivery. These are more likely if you are using more doses than you actually need, or if you are also using another NRT product at the same time without guidance.

  • Headache
  • Nausea or stomach discomfort
  • Dizziness or light-headedness
  • Palpitations (awareness of your heartbeat)
  • Nasal congestion
  • Skin flushing or warmth
  • Hiccups
  • Dry mouth

If you notice nausea or dizziness, try reducing the number of doses you use per day. These symptoms often indicate that your nicotine intake is slightly higher than your body needs at this stage of your quit attempt.

What Are the Serious Side Effects of Nicorette Nasal Spray?

Serious side effects are rare but require prompt medical attention. Stop using the spray and seek immediate help if you experience any of the following:

  • Chest pain or tightness
  • Irregular or rapid heartbeat (palpitations that feel severe)
  • Difficulty breathing or swallowing
  • Swelling of the face, lips, tongue, or throat — this may indicate a serious allergic reaction (anaphylaxis)
  • Severe skin rash or hives

These reactions are uncommon, but if they occur, do not delay seeking emergency medical care. Call 999 or go to your nearest A&E department immediately.

What Should You Do If You Experience Side Effects of Nicorette Nasal Spray?

For mild nasal side effects, no specific treatment is usually needed — they tend to resolve on their own within the first week. Breathing through your mouth for a few seconds after each dose can help reduce the initial irritation. For nicotine-related side effects such as nausea or headache, try reducing your dose frequency and ensure you are not using more sprays than necessary.

You can report any suspected side effects to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. This helps regulators monitor the safety of medicines in real-world use. Always keep your pharmacist informed of any side effects you experience during your quit attempt.

Can Nicorette Nasal Spray Interact With Other Medicines?

No clinically significant pharmacokinetic interactions have been identified between nicotine replacement therapy and other medicines at therapeutic doses. However, stopping smoking itself — rather than the NRT product — can alter how your body metabolises certain medicines. If you take theophylline, clozapine, or warfarin, your prescriber may need to review your dose once you have stopped smoking, as blood levels of these medicines can change. Always inform your GP and pharmacist that you are quitting smoking so they can monitor you appropriately.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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