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Nasonex

Nasonex

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  • ✔️ Relieves nasal congestion, sneezing, and runny nose
  • ✔️ Contains mometasone furoate 50mcg per actuation
  • ✔️ Once-daily dosing for convenient allergy control
  • ✔️ Suitable for adults with seasonal allergic rhinitis
  • ✔️ Low systemic absorption — less than 0.1% bioavailability

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What Is Nasonex Nasal Spray and How Can It Help?

 

If you suffer from a blocked, runny, or itchy nose — especially during pollen season — you will know how much it can affect your daily life. Nasonex nasal spray contains mometasone furoate 50mcg per actuation, a well-established intranasal corticosteroid used to relieve and prevent the symptoms of allergic rhinitis, including seasonal hay fever. It is available to buy without a prescription for adults aged 18 and over, making it a convenient option for managing nasal allergy symptoms at home. You can explore our full range of allergy and hay fever treatments if you need additional support alongside your nasal spray.

Allergic rhinitis affects millions of people in the UK every year. According to the NHS, hay fever alone is estimated to affect around one in five people at some point in their lives. Nasonex works locally in the nasal passages, meaning very little of the active ingredient is absorbed into the bloodstream — which is one reason it is considered well-tolerated for regular use when used as directed.

 

How Does Nasonex Nasal Spray Work?

 

Mometasone furoate belongs to the corticosteroid class of medicines. When you spray it into your nostrils, it acts directly on the nasal lining to reduce inflammation caused by allergens. Here is how it works step by step:

  • Allergens such as pollen, dust mites, or animal dander trigger an immune response in the nasal passages.
  • This immune response causes the release of inflammatory chemicals, including histamine and leukotrienes.
  • Mometasone furoate inhibits the production and release of these inflammatory mediators.
  • The result is reduced swelling, congestion, sneezing, itching, and nasal discharge.
  • Because it acts locally, systemic absorption is minimal at recommended doses.

It is worth noting that Nasonex does not work instantly. Most people notice a meaningful improvement within one to two days, but the full benefit may take up to two weeks of regular use. Starting treatment a couple of weeks before your typical allergy season begins can help you stay ahead of symptoms.

 

Who Should Use Nasonex Nasal Spray?

 

Nasonex is suitable for a broad range of patients, but it is not right for everyone. When purchased over the counter, it is indicated for adults aged 18 and over for the treatment of seasonal allergic rhinitis. On prescription, it can also be used in children aged 6 and over and for perennial (year-round) allergic rhinitis. It may be a good option if you:

  • Experience hay fever symptoms such as sneezing, nasal congestion, or a runny nose during pollen season.
  • Have been diagnosed with perennial allergic rhinitis triggered by dust mites or pet dander.
  • Have tried antihistamines but found they do not adequately control your nasal symptoms.
  • Prefer a non-drowsy treatment that targets the nose directly rather than acting systemically.

It is not suitable for people who have recently had nasal surgery or a nasal injury, or those with untreated nasal infections. Always speak to your pharmacist or GP if you are unsure whether Nasonex is appropriate for you.

 

How Does Nasonex Compare to Other Nasal Sprays?

 

Feature Nasonex (Mometasone) Flixonase (Fluticasone)
Active ingredient Mometasone furoate 50mcg Fluticasone propionate 50mcg
Age (OTC use) 18 years and over 18 years and over
Dosing frequency Once daily Once daily
Systemic bioavailability Less than 0.1% Approximately 2%

 

Is Nasonex Nasal Spray Safe for Long-Term Use?

 

For most adults, Nasonex nasal spray is considered safe for ongoing use when taken at the recommended dose. Because mometasone furoate has very low systemic bioavailability — less than 0.1% — the risk of systemic corticosteroid side effects is minimal compared to oral steroids. That said, long-term use should still be reviewed periodically by a healthcare professional, particularly in children, to monitor for any effect on growth. If you are managing multiple allergy symptoms, our ear, nose, and throat collection includes a range of complementary products that may help.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Nasonex specifications
Treatment category Allergic rhinitis / Hay fever
Active ingredient Mometasone furoate 50mcg per actuation
Mechanism of action Intranasal corticosteroid — reduces nasal inflammation
Effective for Seasonal and perennial allergic rhinitis
Suitable for Adults 18+ (OTC); children 6+ (prescription)
Pack sizes 140 actuations
Strengths 50mcg per actuation
UK classification Pharmacy (P) medicine
Drug class Corticosteroid
Preparation Aqueous nasal suspension
Route of administration Intranasal

Specifications of Nasonex

 

What Is Nasonex and What Is It Used For?

 

Nasonex nasal spray contains mometasone furoate 50mcg per actuation. It is an intranasal corticosteroid used to treat the symptoms of seasonal allergic rhinitis (hay fever) and perennial allergic rhinitis in adults and children aged 6 and over. Symptoms it helps to relieve include nasal congestion, sneezing, a runny nose, and nasal itching. When purchased over the counter in the UK, it is indicated for adults aged 18 and over for seasonal allergic rhinitis only.

 

What Do You Need to Know Before Using Nasonex?

 

Before using Nasonex, it is important to check whether it is appropriate for you. Do not use this spray if any of the following apply:

  • You are allergic to mometasone furoate or any other ingredient in the spray.
  • You have a current nasal or sinus infection that has not been treated.
  • You have recently had nasal surgery or a nasal injury — wait until healing is complete.
  • You are under 18 years of age and purchasing without a prescription.
  • You have tuberculosis (active or latent) or any other untreated systemic infection.

The following medicines may interact with mometasone furoate and increase the amount of corticosteroid in your bloodstream:

  • Ketoconazole (an antifungal medicine)
  • Ritonavir and other HIV protease inhibitors
  • Other corticosteroid medicines (inhaled, oral, or topical)

Always tell your pharmacist or doctor about all medicines you are currently taking, including herbal remedies and supplements.

 

How Should You Use Nasonex Nasal Spray?

 

Using Nasonex correctly makes a real difference to how well it works. Follow these steps each time you use it:

  1. Shake the bottle gently before each use.
  2. If using for the first time, or if you have not used it for several days, prime the pump by pressing it firmly several times until a fine mist appears.
  3. Blow your nose gently to clear the nostrils.
  4. Tilt your head slightly forward — do not tilt it back.
  5. Insert the nozzle into one nostril, aiming slightly away from the nasal septum (the central dividing wall).
  6. Press the pump once while breathing in gently through your nose.
  7. Repeat in the other nostril.
  8. Breathe out through your mouth. Avoid blowing your nose for several minutes after use.
  9. Wipe the nozzle clean and replace the cap after each use.
Indication Age Group Dose Frequency
Seasonal allergic rhinitis (OTC) Adults 18+ 2 sprays per nostril (200mcg total) Once daily
Seasonal allergic rhinitis (Rx) Children 6–11 1 spray per nostril (100mcg total) Once daily
Perennial allergic rhinitis (Rx) Adults & children 12+ 2 sprays per nostril (200mcg total) Once daily

 

What Are the Possible Side Effects of Nasonex?

 

Like all medicines, Nasonex can cause side effects, although not everyone experiences them. Most side effects are mild and affect the nose or throat locally.

Common side effects (may affect up to 1 in 10 people):

  • Nasal irritation, stinging, or burning
  • Nosebleeds (epistaxis)
  • Headache
  • Nasal dryness or crusting

Less common side effects (may affect up to 1 in 100 people):

  • Unpleasant taste or smell
  • Nasal ulceration
  • Throat irritation
  • Sneezing immediately after use

Rarely, prolonged use of intranasal corticosteroids may affect the nasal septum. If you notice any visual disturbances, persistent nosebleeds, or signs of a nasal perforation, stop using the spray and seek medical advice promptly. If you are also managing eye-related allergy symptoms, our eye care range includes antihistamine eye drops that may complement your treatment.

 

How Should You Store Nasonex?

 

Correct storage helps maintain the quality and effectiveness of your nasal spray. Follow these guidelines:

  • Store below 25°C in a cool, dry place.
  • Keep the bottle upright at all times.
  • Do not freeze or expose to direct sunlight.
  • Keep out of the reach and sight of children.
  • Do not use after the expiry date printed on the label.
  • Discard the bottle within the period stated in the patient information leaflet after opening.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Nasonex nasal spray online in the UK?

You can buy Nasonex nasal spray from Cured Pharmacy, a GPhC-registered UK online pharmacy, for £29.99. It is available as a Pharmacy (P) medicine for adults aged 18 and over without a prescription for seasonal allergic rhinitis. Simply complete a short online consultation and your order will be dispatched quickly and discreetly. You can also browse our full allergy and hay fever range for additional treatment options.

How does Nasonex nasal spray work in the body?

Nasonex contains mometasone furoate, a corticosteroid that reduces inflammation in the nasal lining by blocking the release of inflammatory chemicals such as histamine and leukotrienes. It acts locally in the nasal passages, so very little of the active ingredient enters the bloodstream. This targeted action means it relieves congestion, sneezing, and a runny nose without causing the drowsiness associated with oral antihistamines.

How do I use Nasonex nasal spray step by step?

Shake the bottle gently, then prime the pump before first use by pressing it several times until a fine mist appears. Tilt your head slightly forward, insert the nozzle into one nostril, and press the pump once while breathing in gently through your nose. Repeat in the other nostril, then breathe out through your mouth and avoid blowing your nose for a few minutes afterwards.

What is the correct dose of Nasonex for adults?

The standard adult dose is two sprays into each nostril once daily, delivering a total of 200mcg of mometasone furoate per day. Once your symptoms are well controlled, a doctor may reduce this to one spray per nostril once daily as a maintenance dose. Always follow the instructions in the patient information leaflet and do not exceed the recommended dose.

What is the best time of day to use Nasonex nasal spray?

There is no strict requirement to use Nasonex at a specific time of day, but using it at the same time each day helps you build a consistent routine and maintain steady levels of the medicine in your nasal passages. Many people find it easiest to use it in the morning as part of their daily routine. If you are using it for hay fever prevention, starting treatment a couple of weeks before your pollen season begins can help you stay ahead of symptoms.

What are the common side effects of Nasonex nasal spray?

The most commonly reported side effects include nasal irritation, stinging or burning inside the nose, nosebleeds, headache, and nasal dryness. These effects are usually mild and often improve as your nose adjusts to the spray over the first few days of use. If nosebleeds are frequent or severe, stop using the spray and speak to your pharmacist or GP.

How do I manage side effects of Nasonex nasal spray?

To reduce nasal irritation, make sure you are aiming the nozzle slightly away from the nasal septum (the central wall of your nose) rather than directly at it. Using a saline nasal rinse before applying the spray can also help keep the nasal lining moist and reduce dryness. If side effects persist or worsen, contact your pharmacist for advice before continuing use.

Who is eligible to use Nasonex nasal spray?

When purchased over the counter, Nasonex is suitable for adults aged 18 and over who have been previously diagnosed with seasonal allergic rhinitis by a doctor. On prescription, it can also be used in children aged 6 and over and for perennial (year-round) allergic rhinitis. It is not suitable for people with recent nasal surgery, untreated nasal infections, or a known allergy to mometasone furoate.

What happens if I miss a dose of Nasonex?

If you forget to use your Nasonex nasal spray, use it as soon as you remember — unless it is nearly time for your next scheduled dose, in which case simply skip the missed one. Never use a double dose to compensate for a forgotten one. Consistent daily use is important for getting the full benefit from this medicine, so try to use it at the same time each day.

Can I use Nasonex nasal spray during pregnancy?

If you are pregnant or planning to become pregnant, you should speak to your GP or midwife before using Nasonex nasal spray. While intranasal corticosteroids are generally considered lower risk than oral steroids during pregnancy, the decision should be made on an individual basis with a healthcare professional. Do not start or continue using Nasonex during pregnancy without medical advice.

Can children use Nasonex nasal spray?

Nasonex can be prescribed for children aged 6 and over for seasonal and perennial allergic rhinitis, but it cannot be purchased over the counter for children — OTC use is restricted to adults aged 18 and over. If your child needs treatment for allergic rhinitis, speak to your GP who can assess whether a prescription is appropriate. Long-term use in children should be monitored to check for any effect on growth.

What are the alternatives to Nasonex nasal spray?

Other intranasal corticosteroids available in the UK include fluticasone propionate (Flixonase) and beclometasone dipropionate (Beconase), both of which work in a similar way to mometasone furoate. Antihistamine nasal sprays such as azelastine are another option, particularly for rapid symptom relief. You can explore our ear, nose, and throat collection for a broader range of nasal allergy treatments.

How long does it take for Nasonex to start working?

Most people notice some improvement in their nasal symptoms within one to two days of starting Nasonex, but the full therapeutic effect may take up to two weeks of regular daily use. This is why it is recommended to start using the spray a couple of weeks before your allergy season begins if possible. Do not stop using it after just a day or two if you do not notice an immediate effect — consistency is key.

How long can you use Nasonex nasal spray for?

When purchased over the counter, Nasonex should not be used for more than three months without consulting a doctor. For longer-term or year-round use, a GP should review your treatment to ensure it remains appropriate and to monitor for any side effects. If you have been using it for several months and your symptoms are not well controlled, speak to your GP about alternative or additional treatments.

What are the latest studies on mometasone furoate nasal spray?

Mometasone furoate has been extensively studied and is well-established as an effective first-line treatment for allergic rhinitis in clinical guidelines. Research consistently shows it reduces nasal symptoms with minimal systemic absorption due to its very low bioavailability of less than 0.1%. Current NHS and NICE guidance supports intranasal corticosteroids, including mometasone, as the preferred treatment for moderate-to-severe allergic rhinitis symptoms.

How Should You Use Nasonex Nasal Spray?

Using Nasonex correctly is essential for getting the most out of your treatment. Always read the patient information leaflet before starting, and follow these steps each time you use the spray.

What Is the Correct Dose of Nasonex?

The dose of Nasonex varies depending on your age and the condition being treated. Always follow the dose recommended by your doctor or pharmacist, and never exceed the stated dose without medical advice.

When Is the Best Time to Use Nasonex?

Nasonex can be used at any time of day, but using it at the same time each day helps you maintain a consistent routine and ensures steady levels of the medicine in your nasal passages. Many people find it easiest to incorporate it into their morning routine. If you are using Nasonex to prevent hay fever symptoms, starting treatment one to two weeks before your typical pollen season begins gives the medicine time to build up its anti-inflammatory effect before allergen exposure peaks.

How Long Can You Use Nasonex For?

When purchased over the counter, Nasonex should not be used for longer than three months without consulting a doctor or pharmacist. For seasonal hay fever, you would typically use it throughout the pollen season and then stop. If you need treatment for year-round (perennial) allergic rhinitis, your GP can prescribe Nasonex for longer-term use and will review your treatment periodically to ensure it remains appropriate. Do not use Nasonex for longer than recommended without medical supervision, particularly in children, where growth should be monitored during extended use.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Nasonex Nasal Spray?

Most people who use Nasonex tolerate it well, but like all medicines it can cause side effects in some people. The most common side effects affect the nose and throat locally and are generally mild. They often improve on their own as your body adjusts to the spray over the first few days of use.

  • Nasal irritation, stinging, or burning sensation inside the nose
  • Nosebleeds (epistaxis)
  • Headache
  • Nasal dryness or crusting
  • Sneezing immediately after using the spray

What Are the Less Common Side Effects of Nasonex?

Less commonly, some people experience side effects that are still localised to the nose and throat but are less frequently reported. If any of these persist or become bothersome, speak to your pharmacist before continuing treatment.

  • Unpleasant or altered taste or smell
  • Throat irritation or soreness
  • Nasal ulceration
  • Nasal congestion that temporarily worsens after use
  • Watery eyes

What Are the Serious Side Effects of Nasonex?

Serious side effects from Nasonex are rare, particularly because mometasone furoate has very low systemic absorption at recommended doses. However, you should be aware of the following and seek medical attention promptly if they occur.

  • Nasal septum perforation — a hole developing in the wall between the nostrils, which may present as a whistling sound when breathing through the nose.
  • Signs of adrenal suppression with very prolonged use — such as unusual tiredness, weakness, or dizziness.
  • Visual disturbances, including blurred vision — which may indicate raised intraocular pressure or cataracts with long-term use.
  • Allergic reactions — including rash, swelling of the face or throat, or difficulty breathing. Seek emergency help immediately if this occurs.

What Should You Do If You Experience Side Effects?

If you experience mild side effects such as nasal irritation or occasional nosebleeds, try adjusting your technique — aim the nozzle slightly away from the nasal septum and avoid pressing too hard. Using a saline nasal rinse before applying the spray can also help. If side effects are persistent, severe, or concern you in any way, stop using Nasonex and contact your pharmacist or GP for advice. You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Nasonex Interact With Other Medicines?

Nasonex nasal spray has a low potential for drug interactions because so little of the active ingredient is absorbed into the bloodstream. However, medicines that inhibit the liver enzyme CYP3A4 — such as ketoconazole (an antifungal) and ritonavir (an HIV medicine) — can increase mometasone levels in the body and should be used with caution alongside Nasonex. Using multiple corticosteroid products at the same time (for example, an inhaled steroid for asthma plus Nasonex) may also increase the overall corticosteroid load. Always tell your pharmacist or doctor about every medicine you are taking before starting Nasonex.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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