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Mometasone Furoate

Mometasone Furoate

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  • ✔️ Relieves nasal congestion, sneezing, and itching from allergies
  • ✔️ Once-daily dosing for consistent, all-day symptom control
  • ✔️ Less than 1% systemic absorption — minimal whole-body steroid effects
  • ✔️ Effective for both seasonal hay fever and year-round allergic rhinitis
  • ✔️ Can be started before pollen season to prevent symptoms developing

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What Is Mometasone Furoate Nasal Spray?

 

If you struggle with a blocked, runny, or itchy nose every time pollen season arrives — or even year-round — you are far from alone. Allergic rhinitis affects millions of people across the UK, and finding something that actually works can feel like a challenge. Mometasone furoate nasal spray is a corticosteroid nasal spray licensed for the treatment and prevention of seasonal and perennial allergic rhinitis in adults. It is available over the counter for adults aged 18 and over, and you can browse our full range of allergy and hay fever treatments to find the right option for you.

The active ingredient, mometasone furoate 50 micrograms per actuation, works locally inside the nasal passages with minimal absorption into the bloodstream. That makes it a well-tolerated choice for many people who need ongoing symptom relief without the drowsiness sometimes associated with antihistamine tablets.

 

How Does Mometasone Furoate Nasal Spray Work?

 

Corticosteroids like mometasone work by dampening down the inflammatory response triggered by allergens such as pollen, dust mites, or pet dander. When you inhale an allergen, your immune system releases chemicals — including histamine, prostaglandins, and leukotrienes — that cause the classic symptoms of a blocked, streaming nose. Mometasone interrupts this process at a cellular level.

  • Binds to glucocorticoid receptors inside nasal mucosal cells
  • Suppresses the release of pro-inflammatory cytokines and mediators
  • Reduces swelling and mucus production in the nasal lining
  • Provides relief from congestion, sneezing, itching, and a runny nose

Because it acts locally rather than systemically, the risk of whole-body steroid side effects is very low at the recommended dose. Regular daily use is key — the spray works best when used consistently, not just on bad days.

 

Who Should Use Mometasone Furoate Nasal Spray?

 

This spray is suitable for adults aged 18 and over who experience nasal symptoms caused by allergies. It can be used both to treat symptoms once they appear and to prevent them if you start using it a few days before your allergy season begins. It is particularly useful for people who find antihistamines alone are not enough to control nasal congestion.

  • Adults with seasonal allergic rhinitis (hay fever)
  • Adults with perennial allergic rhinitis (year-round allergies)
  • People whose nasal symptoms are not adequately controlled by antihistamines alone
  • Those who prefer a non-drowsy treatment option

 

How Does Mometasone Furoate Compare to Other Nasal Sprays?

 

Feature Mometasone Furoate Beclometasone Nasal Spray
Drug class Corticosteroid Corticosteroid
Dosing frequency Once daily Twice daily (some formulations)
Systemic bioavailability Less than 1% Approximately 44%
OTC availability (UK) Yes (adults 18+) Yes (adults 18+)

 

Is Mometasone Furoate Nasal Spray Safe to Store at Home?

 

Yes. Store the bottle upright at room temperature, below 25°C. Keep it away from direct sunlight and do not freeze it. Once opened, the spray should be used within the period stated on the packaging — typically within three months. Keep it out of the reach and sight of children. If you are also managing skin conditions alongside your allergy symptoms, you may find our skin care range helpful for any associated irritation around the nose.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Mometasone Furoate Nasal Spray specifications
Treatment category Allergic rhinitis / Hay fever
Mechanism of action Intranasal corticosteroid — reduces nasal inflammation
Effective for Nasal congestion, sneezing, itching, runny nose
Suitable for Adults aged 18 and over
Active ingredient Mometasone furoate 50 micrograms per actuation
Strengths 50 mcg per spray
UK classification Pharmacy (P) medicine
Drug class Corticosteroid
Preparation Aqueous nasal spray suspension
Route of administration Intranasal

Specifications of Mometasone Furoate Nasal Spray

 

What Is Mometasone Furoate Nasal Spray and What Is It Used For?

 

Mometasone furoate nasal spray is an intranasal corticosteroid used to relieve and prevent the nasal symptoms of allergic rhinitis — both seasonal (such as hay fever caused by grass or tree pollen) and perennial (year-round allergies triggered by dust mites, mould, or pet dander). It reduces inflammation inside the nasal passages, helping to ease congestion, sneezing, itching, and a runny nose. It is available over the counter in the UK for adults aged 18 and over.

 

What Do You Need to Know Before Using Mometasone Furoate Nasal Spray?

 

Before using this spray, make sure it is appropriate for you. Do not use it if any of the following apply:

  • You are allergic to mometasone furoate or any other ingredient in the spray
  • You have had recent nasal surgery or a nasal injury that has not yet healed
  • You have an untreated nasal or sinus infection
  • You are under 18 years of age (for OTC use)
  • You are pregnant or breastfeeding — seek medical advice first

Some medicines can interact with mometasone furoate. Tell your pharmacist or doctor if you are taking any of the following:

  • Ketoconazole or other azole antifungals — may increase mometasone levels in the blood
  • Ritonavir or other HIV protease inhibitors — may increase systemic corticosteroid exposure
  • Other corticosteroid medicines (inhaled, oral, or topical) — combined use increases the risk of systemic effects

 

How Should You Use Mometasone Furoate Nasal Spray?

 

Using the spray correctly makes a real difference to how well it works. Follow these steps each time:

  1. Shake the bottle gently before use
  2. Blow your nose to clear the nasal passages
  3. Remove the protective cap from the nozzle
  4. Tilt your head slightly forward — do not tilt it back
  5. Insert the nozzle gently into one nostril, pointing it slightly away from the centre of your nose
  6. Press the pump firmly and breathe in gently through your nose at the same time
  7. Breathe out through your mouth — do not sniff hard
  8. Repeat for the other nostril
  9. Wipe the nozzle clean and replace the cap
Indication Age Group Dose Frequency
Seasonal allergic rhinitis (treatment) Adults 18+ 2 sprays per nostril (100 mcg each nostril) Once daily
Seasonal allergic rhinitis (maintenance) Adults 18+ 1 spray per nostril (50 mcg each nostril) Once daily
Perennial allergic rhinitis Adults 18+ 2 sprays per nostril (100 mcg each nostril) Once daily

If you are also experiencing eye symptoms alongside your nasal allergy, our eye care range includes antihistamine eye drops that can be used alongside this nasal spray.

 

What Are the Possible Side Effects of Mometasone Furoate Nasal Spray?

 

Like all medicines, mometasone furoate nasal spray can cause side effects, although not everyone experiences them. Most side effects are mild and localised to the nose and throat.

Common side effects (may affect up to 1 in 10 people):

  • Nasal irritation or stinging
  • Headache
  • Nosebleeds (epistaxis)
  • Burning sensation in the nose or throat
  • Sneezing immediately after use

Less common side effects (may affect up to 1 in 100 people):

  • Nasal ulceration or crusting
  • Unpleasant taste or smell
  • Throat irritation
  • Raised intraocular pressure (with prolonged use — seek medical advice)
  • Nasal septal perforation (rare, with long-term use)

Systemic corticosteroid effects are very unlikely at the recommended dose due to the extremely low bioavailability of mometasone furoate. However, if you use multiple corticosteroid products simultaneously, speak to your pharmacist. You can also explore our ear, nose and throat range for complementary products.

 

How Should You Store Mometasone Furoate Nasal Spray?

 

  • Store below 25°C at room temperature
  • Keep the bottle upright at all times
  • Do not freeze or expose to direct sunlight
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the label
  • Once opened, use within the period stated on the packaging (typically three months)
  • Dispose of unused medicine responsibly — return to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy mometasone furoate nasal spray online in the UK?

You can buy mometasone furoate nasal spray online from Cured Pharmacy, a GPhC-registered UK online pharmacy, without a prescription if you are aged 18 or over. It is classified as a Pharmacy (P) medicine, meaning it is available over the counter but must be sold under pharmacist supervision. Browse our allergy and hay fever collection to order quickly and conveniently.

How does mometasone furoate nasal spray work in the body?

Mometasone furoate is a corticosteroid that binds to glucocorticoid receptors in the cells lining the nasal passages, suppressing the release of inflammatory chemicals such as histamine, prostaglandins, and leukotrienes. This reduces swelling, mucus production, and irritation in the nose. Because it acts locally with less than 1% systemic bioavailability, it is unlikely to cause the whole-body effects associated with oral steroids.

How do I use mometasone furoate nasal spray step by step?

Shake the bottle gently, blow your nose, then tilt your head slightly forward. Insert the nozzle into one nostril pointing slightly away from the nasal septum, press the pump, and breathe in gently through your nose at the same time. Repeat for the other nostril, then wipe the nozzle and replace the cap — do not sniff hard after spraying.

What is the correct dose of mometasone furoate nasal spray for adults?

The standard starting dose for adults is two sprays (100 micrograms) into each nostril once daily, giving a total daily dose of 200 micrograms. Once your symptoms are well controlled, your doctor or pharmacist may advise reducing to one spray per nostril once daily. Never exceed two sprays per nostril per day.

How long does mometasone furoate nasal spray take to work?

Some improvement may be noticed within 12 hours of the first dose, but the full therapeutic effect typically develops after several days of consistent daily use. For seasonal allergies such as hay fever, it is worth starting the spray a few days before your expected pollen season to get ahead of symptoms. Do not stop using it just because you feel better — regular use gives the best results.

What are the common side effects of mometasone furoate nasal spray?

The most commonly reported side effects include nasal irritation or stinging, headache, nosebleeds, and a burning sensation in the nose or throat. These effects are usually mild and tend to settle with continued use. If you experience persistent or severe nosebleeds, stop using the spray and speak to your pharmacist or GP.

Who should not use mometasone furoate nasal spray?

You should not use this spray if you are allergic to mometasone furoate or any of its excipients, have had recent nasal surgery or injury that has not fully healed, or have an active nasal or sinus infection. It is not licensed for OTC use in people under 18, and you should seek medical advice before using it if you are pregnant or breastfeeding. People taking certain antifungal or antiviral medicines should also consult a pharmacist first.

Can I use mometasone furoate nasal spray long term?

For OTC use, mometasone furoate nasal spray should not be used for longer than three months without consulting a doctor or pharmacist. Under medical supervision, it can be used for extended periods, particularly for perennial allergic rhinitis. Long-term use should be monitored to check for nasal mucosal changes and, in rare cases, raised intraocular pressure.

What happens if I miss a dose of mometasone furoate nasal spray?

If you forget to use your spray, take the missed dose as soon as you remember — unless it is almost time for your next dose, in which case simply skip the missed one. Do not use a double dose to make up for a forgotten one. Consistent daily use is important for the spray to work effectively, so try to use it at the same time each day.

Can I use mometasone furoate nasal spray during pregnancy?

If you are pregnant or planning to become pregnant, you should speak to your doctor or pharmacist before using mometasone furoate nasal spray. While systemic absorption is very low, corticosteroids should only be used during pregnancy when the benefit clearly outweighs any potential risk. Your healthcare provider can help you weigh up your options.

Does mometasone furoate nasal spray interact with other medicines?

Yes, some medicines can increase the amount of mometasone absorbed into the bloodstream. These include ketoconazole and other azole antifungals, as well as ritonavir and other HIV protease inhibitors. Using multiple corticosteroid products at the same time — such as an inhaled steroid and this nasal spray — may also increase the risk of systemic effects. Always tell your pharmacist about all medicines you are taking.

What are the alternatives to mometasone furoate nasal spray?

Other intranasal corticosteroids available in the UK include beclometasone dipropionate and fluticasone propionate nasal sprays, which are also available over the counter. Antihistamine tablets or nasal sprays such as cetirizine or azelastine are another option, particularly for milder symptoms. Your pharmacist can help you choose the most suitable treatment based on your symptoms and medical history.

Is mometasone furoate nasal spray the same as Nasonex?

Yes — Nasonex is a branded version of mometasone furoate nasal spray containing the same active ingredient at the same strength (50 micrograms per actuation). Generic mometasone furoate nasal spray contains the same active ingredient and works in the same way, but is typically available at a lower price. Both are equally effective when used correctly.

Can mometasone furoate nasal spray help with nasal polyps?

Mometasone furoate nasal spray is licensed for the treatment of nasal polyps in adults, but this is a prescription-only indication in the UK and requires a higher dose than the OTC version. If you think you have nasal polyps — which can cause persistent blockage and loss of smell — you should see your GP for assessment and appropriate treatment. Do not attempt to self-treat nasal polyps with an OTC nasal spray without medical advice.

What are the latest studies on mometasone furoate nasal spray?

Clinical evidence consistently supports mometasone furoate as one of the most effective intranasal corticosteroids for allergic rhinitis, with a well-established safety profile built over decades of use. Its very low systemic bioavailability (less than 1%) distinguishes it from older corticosteroids such as beclometasone. Ongoing research continues to explore its role in managing conditions such as chronic rhinosinusitis and nasal polyps, with guidelines from NICE and the NHS supporting its use in appropriate patients. You can also explore our ear, nose and throat range for related products.

How Should You Use Mometasone Furoate Nasal Spray?

Using your nasal spray correctly is just as important as using it regularly. Poor technique is one of the most common reasons people feel the spray is not working — so it is worth taking a moment to get it right.

Follow these steps each time you use the spray:

If the pump has not been used for several days, prime it by pressing it a few times until a fine mist appears before using it in your nose.

What Is the Correct Dose of Mometasone Furoate Nasal Spray?

The dose depends on your symptoms and whether you are using the spray to treat or prevent allergic rhinitis. Always follow the instructions provided with your spray or the advice of your pharmacist.

Do not exceed two sprays per nostril per day. If your symptoms are not improving after two weeks of regular use, speak to your pharmacist or GP.

When Is the Best Time to Use Mometasone Furoate Nasal Spray?

There is no strict rule about the time of day, but using the spray at the same time each day helps you build a consistent routine and reduces the chance of missing a dose. Many people find it easiest to use it in the morning as part of their daily routine. If you are using it for hay fever, starting a few days before your pollen season begins can help prevent symptoms from taking hold in the first place.

If you miss a dose, take it as soon as you remember — unless it is nearly time for your next dose, in which case skip the missed one. Never double up.

How Long Can You Use Mometasone Furoate Nasal Spray For?

For over-the-counter use, mometasone furoate nasal spray should not be used for more than three months without seeking advice from a doctor or pharmacist. If your symptoms persist beyond this period, or if they worsen at any point, it is important to get a medical review. Under prescription and medical supervision, the spray can be used for longer periods — particularly for people with perennial allergic rhinitis or nasal polyps.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Mometasone Furoate Nasal Spray?

Most people tolerate mometasone furoate nasal spray well, and side effects are generally mild and localised to the nose and throat. Because the spray acts locally with very low systemic absorption, whole-body steroid effects are unlikely at the recommended dose.

  • Nasal irritation or stinging inside the nose
  • Headache
  • Nosebleeds (epistaxis)
  • Burning sensation in the nose or throat
  • Sneezing immediately after using the spray

What Are the Less Common Side Effects of Mometasone Furoate Nasal Spray?

Less common side effects occur in fewer people but are still worth being aware of. If you notice any of the following, speak to your pharmacist or GP, particularly if they persist or worsen.

  • Nasal ulceration or crusting inside the nose
  • Unpleasant taste or smell
  • Throat irritation or dryness
  • Nasal septal perforation (a hole in the nasal septum — rare, associated with long-term use)
  • Raised intraocular pressure or worsening of glaucoma (with prolonged use)
  • Cataracts (rare, with long-term use)

What Are the Serious Side Effects of Mometasone Furoate Nasal Spray?

Serious side effects are rare but can occur, particularly with prolonged use or when combined with other corticosteroid medicines. Signs of systemic corticosteroid effects — such as unusual weight gain, a rounded face, easy bruising, or muscle weakness — should be reported to your GP promptly. Allergic reactions to the spray itself are also possible, though uncommon. Seek immediate medical attention if you develop swelling of the face, lips, or throat, difficulty breathing, or a severe skin rash after using the spray.

What Should You Do If You Experience Side Effects of Mometasone Furoate Nasal Spray?

For mild side effects such as nasal irritation or occasional nosebleeds, try adjusting your technique — make sure you are angling the nozzle away from the nasal septum and not sniffing hard after spraying. Rinsing your nose with saline before use can also help. If side effects are persistent, severe, or worrying, stop using the spray and contact your pharmacist or GP. You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Mometasone Furoate Nasal Spray Interact With Other Medicines?

Yes. Certain medicines can increase the amount of mometasone absorbed into the bloodstream, raising the risk of systemic corticosteroid effects. These include ketoconazole and other azole antifungal medicines, as well as ritonavir and other HIV protease inhibitors. Using this spray alongside other corticosteroid products — such as inhaled steroids for asthma or topical steroids for skin conditions — may also increase systemic exposure. Always tell your pharmacist about every medicine you are taking, including over-the-counter products and supplements.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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