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Migraleve Pink - 12 Tablets

Migraleve Pink - 12 Tablets

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  • ✔️ Targets both migraine pain and nausea simultaneously
  • ✔️ Contains buclizine to relieve migraine-associated sickness
  • ✔️ Triple-action formula: buclizine, paracetamol, and codeine
  • ✔️ Suitable for adults and young people aged 12 and over
  • ✔️ Works best when taken at the very first migraine sign

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What Are Migraleve Pink Tablets and How Do They Help Migraines?

 

If you've ever been hit by a migraine, you'll know it's far more than just a headache. The throbbing pain, the sensitivity to light, the wave of nausea — it can stop your day completely. Migraleve Pink tablets are a well-established over-the-counter option designed to tackle both the pain and the sickness that so often come together during a migraine attack. Each pack contains 12 tablets, priced at just £6.99, making them an accessible choice for adults and young people aged 12 and over. You can find them alongside other trusted options in our pain relief collection.

Migraleve Pink is classified as a pharmacy (P) medicine in the UK, meaning it's available without a prescription but should be purchased from a registered pharmacy. The MHRA-approved formulation has been used for decades and remains one of the most recognised migraine treatments available over the counter.

 

How Do Migraleve Pink Tablets Work in the Body?

 

Migraleve Pink tablets work through a combination of three active ingredients, each targeting a different aspect of a migraine attack:

  • Buclizine hydrochloride (6.25 mg) — an antihistamine that acts on the central nervous system to reduce nausea and vomiting, which are common migraine symptoms.
  • Paracetamol (500 mg) — a widely used analgesic that reduces pain by inhibiting prostaglandin synthesis in the brain and peripheral tissues.
  • Codeine phosphate (8 mg) — a mild opioid analgesic that enhances pain relief by binding to opioid receptors in the central nervous system, reducing the perception of pain.

The combination approach is intentional. Migraines often cause delayed gastric emptying, which can reduce how well oral medicines are absorbed. Taking the pink tablets at the very first sign of an attack — before the headache fully develops — gives the ingredients the best chance of working effectively.

 

Who Should Use Migraleve Pink Tablets?

 

Migraleve Pink is suitable for adults and young people aged 12 and over who experience migraine attacks with associated nausea. It's particularly useful if your migraines tend to come with significant sickness, as the buclizine component directly addresses that symptom. That said, it isn't right for everyone.

Migraleve Pink tablets may be suitable if you:

  • Are aged 12 or over and experience migraine headaches with nausea
  • Have previously tolerated paracetamol and codeine without adverse effects
  • Are not currently taking other paracetamol-containing medicines
  • Do not have a known sensitivity or allergy to any of the active ingredients

They are not suitable for children under 12, people with liver or kidney problems, those with a history of codeine sensitivity, or anyone who has been told they are a "ultra-rapid codeine metaboliser." Always read the full patient information leaflet before use.

 

How Do Migraleve Pink Tablets Compare to Migraleve Yellow?

 

Feature Migraleve Pink Migraleve Yellow
Active ingredients Buclizine, Paracetamol, Codeine Paracetamol, Codeine (no buclizine)
Targets nausea Yes No
Pain relief Yes Yes
When to take At first sign of migraine Every 4 hours if pain continues (after pink)

 

How Should You Store Migraleve Pink Tablets?

 

Store Migraleve Pink tablets below 25°C in a dry place, away from direct sunlight. Keep them out of the reach and sight of children at all times. Do not use the tablets after the expiry date printed on the packaging. If you're managing several medicines at home, it's worth keeping a dedicated, secure storage spot — particularly for anything containing codeine. If you're also managing other health conditions, our sickness and nausea collection has additional options that may complement your migraine management plan.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Migraleve Pink 12 Tablets specifications
Treatment category Migraine relief
Mechanism of action Analgesic, antiemetic, and opioid combination
Effective for Migraine headache with associated nausea
Suitable for Adults and children aged 12 and over
Active ingredients Buclizine HCl 6.25 mg, Paracetamol 500 mg, Codeine phosphate 8 mg
Pack size 12 tablets
UK classification Pharmacy (P) medicine
Drug class Analgesic / Antiemetic combination
Preparation Film-coated tablet
Route of administration Oral

Specifications of Migraleve Pink 12 Tablets

 

What Is Migraleve Pink and What Is It Used For?

 

Migraleve Pink tablets are an over-the-counter combination medicine used to relieve the symptoms of migraine attacks in adults and young people aged 12 and over. Each pink tablet contains three active ingredients — buclizine hydrochloride 6.25 mg, paracetamol 500 mg, and codeine phosphate 8 mg — working together to address both the pain and the nausea that characterise a migraine episode. According to the NHS, migraines affect around one in five women and one in fifteen men in the UK, making effective symptom management a real priority for many people.

Migraleve Pink tablets are intended to be taken at the very first sign of a migraine. They are not a preventative treatment and should not be used for general headaches or other types of pain.

 

What Do You Need to Know Before Using Migraleve Pink?

 

Before taking Migraleve Pink tablets, it's important to check whether they are appropriate for you. Do not take these tablets if any of the following apply:

  • You are under 12 years of age
  • You are allergic to paracetamol, codeine, buclizine, or any other ingredient in the tablet
  • You have severe liver or kidney disease
  • You have a condition called phenylketonuria
  • You are an ultra-rapid metaboliser of codeine (a genetic variation that increases the risk of serious side effects)
  • You are breastfeeding — codeine passes into breast milk and can harm a baby
  • You are taking or have recently taken monoamine oxidase inhibitors (MAOIs)

The following medicines may interact with Migraleve Pink. Always tell your pharmacist or doctor if you are taking:

  • Other medicines containing paracetamol or codeine
  • Sedatives, sleeping tablets, or medicines for anxiety
  • Anticoagulants such as warfarin (regular paracetamol use can affect INR)
  • Metoclopramide or domperidone (used for nausea)
  • Alcohol — this increases the sedative effect of codeine

 

How Should You Use Migraleve Pink Tablets?

 

  1. Take two Migraleve Pink tablets at the very first sign of a migraine attack.
  2. Swallow the tablets whole with a full glass of water.
  3. Do not crush or chew the tablets.
  4. If your migraine continues after the pink tablets, you may follow up with Migraleve Yellow tablets (paracetamol and codeine only) every four hours as needed.
  5. Do not take more than two pink tablets in any 24-hour period.
  6. Do not take for more than three days without seeking medical advice.
Age Group Dose Frequency Maximum in 24 hours
Adults and children aged 12+ 2 pink tablets At onset of migraine only 2 pink tablets
Children under 12 Not suitable

If you are also managing other conditions alongside migraines, it may be worth exploring our women's health collection, as hormonal changes are a well-recognised migraine trigger in women.

 

What Are the Possible Side Effects of Migraleve Pink?

 

Like all medicines, Migraleve Pink can cause side effects, although not everyone experiences them. The codeine content in particular carries specific risks that are worth understanding before you take it.

Common side effects (may affect up to 1 in 10 people):

  • Drowsiness or sedation
  • Constipation
  • Dizziness
  • Dry mouth

Less common side effects (may affect up to 1 in 100 people):

  • Nausea or vomiting
  • Skin rash or itching
  • Difficulty urinating
  • Blurred vision
  • Headache worsening with frequent use (medication-overuse headache)

Stop taking Migraleve Pink and seek immediate medical attention if you experience difficulty breathing, severe skin reactions, or signs of an allergic reaction such as swelling of the face, lips, or throat.

 

How Should You Store Migraleve Pink Tablets?

 

  • Store below 25°C in a dry place away from direct heat and sunlight
  • Keep in the original packaging until use
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the carton
  • Do not dispose of medicines via wastewater or household waste — return unused tablets to your pharmacist

If you're looking for additional support between migraine episodes, our vitamins and supplements collection includes options such as magnesium, which some clinical guidelines suggest may help reduce migraine frequency when taken regularly.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Migraleve Pink tablets online in the UK?

You can buy Migraleve Pink 12 Tablets directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £6.99. They are classed as a pharmacy (P) medicine, so they must be purchased from a registered pharmacy — not general retail websites. Browse our full pain relief collection for related products too.

How do Migraleve Pink tablets work in the body?

Migraleve Pink tablets contain three active ingredients that work together: buclizine hydrochloride reduces nausea by acting on the central nervous system, paracetamol reduces pain by inhibiting prostaglandin production, and codeine phosphate enhances pain relief by binding to opioid receptors. This triple-action approach targets both the headache and the sickness that typically accompany a migraine. Taking them at the very first sign of an attack gives the best chance of effective relief.

How do I take Migraleve Pink tablets step by step?

Take two Migraleve Pink tablets at the very first sign of your migraine — ideally before the headache becomes severe. Swallow them whole with a full glass of water; do not crush or chew them. Do not take more than two pink tablets in any 24-hour period, and do not use them for more than three consecutive days without speaking to a doctor.

What is the correct dose of Migraleve Pink for adults?

The recommended adult dose is two Migraleve Pink tablets taken once at the onset of a migraine attack. This is also the maximum dose in any 24-hour period for the pink tablets specifically. If pain continues, Migraleve Yellow tablets (without buclizine) can be taken every four hours as directed — but always follow the full pack instructions.

Can children take Migraleve Pink tablets?

Migraleve Pink tablets are suitable for young people aged 12 and over, using the same adult dose of two tablets at migraine onset. They must not be given to children under 12 years of age under any circumstances, as codeine is not safe for this age group. If your child under 12 experiences migraines, speak to your GP for appropriate treatment options.

What are the side effects of Migraleve Pink tablets?

The most common side effects are drowsiness and constipation, both related to the codeine content. Some people also experience dizziness, dry mouth, or nausea. Rarely, allergic reactions can occur — if you notice swelling of the face, lips, or throat, or have difficulty breathing, stop taking the tablets and seek emergency medical help immediately.

Can I take Migraleve Pink tablets if I am pregnant?

Migraleve Pink is not recommended during pregnancy, particularly in the third trimester, because codeine can affect the baby's breathing and buclizine's safety in pregnancy has not been fully established. If you are pregnant and experiencing migraines, speak to your GP or midwife before taking any medication. They can advise on the safest options for you and your baby.

Can I take Migraleve Pink while breastfeeding?

No — Migraleve Pink should not be taken while breastfeeding. Codeine is converted to morphine in the body and passes into breast milk, which can cause serious harm to a nursing infant, including breathing difficulties. The NHS advises that codeine-containing medicines are contraindicated during breastfeeding. Speak to your GP or pharmacist for a safe alternative.

What happens if I take too many Migraleve Pink tablets?

Taking more than the recommended dose is dangerous, primarily because of the paracetamol content — paracetamol overdose can cause serious liver damage, even if you feel well initially. If you or someone else has taken too many tablets, go to your nearest A&E or call 999 immediately. Always take the packaging with you so medical staff can see exactly what was taken.

What should I do if I miss a dose of Migraleve Pink?

Migraleve Pink is taken as a single dose at the onset of a migraine, not on a regular schedule, so a "missed dose" in the traditional sense doesn't apply. If you didn't take it at the very start of your attack and your migraine is already severe, it may be less effective — but you can still take it if you haven't already had two pink tablets in the past 24 hours. Never double up to compensate.

How long can I use Migraleve Pink tablets for?

Migraleve Pink should not be used for more than three consecutive days without medical advice. Using codeine-containing medicines too frequently — more than 10 to 15 days per month — can actually cause medication-overuse headache, where the treatment itself starts to trigger more frequent headaches. If you find yourself needing migraine relief very regularly, speak to your GP about preventative options.

What are the alternatives to Migraleve Pink tablets?

Alternatives include Migraleve Yellow tablets (paracetamol and codeine without the antiemetic buclizine), sumatriptan 50 mg tablets available from a pharmacist for adults who have a confirmed migraine diagnosis, or standard paracetamol and ibuprofen for milder attacks. You can explore further options in our sickness and nausea collection. Your GP can also discuss prescription triptans or preventative treatments if over-the-counter options aren't providing enough relief.

Can I drink alcohol while taking Migraleve Pink tablets?

You should avoid alcohol while taking Migraleve Pink tablets. Alcohol increases the sedative effect of codeine, which can make drowsiness significantly worse and impair your ability to drive or operate machinery safely. Alcohol is also a well-known migraine trigger for many people, so avoiding it during an attack makes sense on multiple levels.

What are the latest studies on migraine treatment with combination analgesics?

Clinical evidence supports the use of combination analgesics — paracetamol plus an antiemetic — as a first-line approach for acute migraine in people who cannot tolerate or access triptans. The NHS and NICE guidelines acknowledge that early treatment at the onset of symptoms improves outcomes. Research continues to explore the role of preventative treatments, including CGRP inhibitors, for people with frequent migraines who don't respond adequately to acute therapies.

Is Migraleve Pink suitable for people with liver problems?

Migraleve Pink is not suitable for people with severe liver disease, as paracetamol is metabolised by the liver and can cause serious harm if liver function is significantly impaired. People with mild to moderate liver conditions should seek advice from their GP or pharmacist before taking it. Always disclose any liver conditions when speaking to a healthcare professional about migraine treatment.

How Should You Use Migraleve Pink Tablets?

Migraleve Pink tablets are designed to be taken at the very first sign of a migraine attack — not once the headache is already in full swing. Acting early gives the active ingredients the best opportunity to be absorbed and work effectively, particularly given that migraines can slow gastric emptying and reduce how well oral medicines are taken up by the body.

Follow these steps each time you take Migraleve Pink:

What Is the Correct Dose of Migraleve Pink?

The dose of Migraleve Pink is straightforward, but it's important to stick to it precisely — particularly because the tablets contain codeine, which carries a risk of dependence if overused. The table below summarises the dosing guidance:

When Is the Best Time to Use Migraleve Pink?

The best time to take Migraleve Pink is at the very earliest sign of a migraine — ideally during the prodrome or aura phase, before the headache pain becomes severe. Many people experience warning signs such as visual disturbances, mood changes, or neck stiffness before the headache begins; these are your cue to act. Waiting until the pain is intense can reduce the effectiveness of the treatment, as absorption may be impaired once nausea and gastric stasis set in.

There is no specific time of day that is "better" — it simply depends on when your migraine starts. Some people find their attacks tend to occur in the morning or are triggered by disrupted sleep, so being prepared with tablets nearby can make a real difference.

How Long Can You Use Migraleve Pink For?

Migraleve Pink should not be used for more than three consecutive days at a time. If you find yourself needing migraine relief on more than 10 to 15 days per month, this is a sign that you should speak to your GP. Overuse of codeine-containing medicines can lead to medication-overuse headache — a condition where the very medicine you're taking to treat headaches starts to cause them. Your GP can discuss preventative migraine treatments that may reduce how often attacks occur in the first place.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Migraleve Pink?

The most frequently reported side effects of Migraleve Pink are linked to its codeine content. Codeine is a mild opioid, and even at the low dose found in these tablets, it can cause effects on the digestive system and central nervous system. Most people tolerate the tablets well when taken as directed, but it's worth knowing what to look out for.

  • Drowsiness or sedation
  • Constipation
  • Dizziness
  • Dry mouth

What Are the Less Common Side Effects of Migraleve Pink?

Less commonly, some people experience side effects that may require them to stop taking the tablets and seek advice. These are not typical but are worth being aware of, particularly if you are taking Migraleve Pink for the first time.

  • Nausea or vomiting (despite the antiemetic buclizine content)
  • Skin rash or itching
  • Blurred vision
  • Difficulty urinating
  • Headache worsening with frequent use (medication-overuse headache)
  • Mood changes or confusion, particularly in older adults

What Are the Serious Side Effects of Migraleve Pink?

Serious side effects are rare but require immediate medical attention. Stop taking Migraleve Pink and seek emergency help if you experience any of the following:

  • Signs of an allergic reaction: swelling of the face, lips, tongue, or throat; difficulty breathing; severe skin rash or hives
  • Slow or shallow breathing — a sign of codeine toxicity, particularly in ultra-rapid metabolisers
  • Severe abdominal pain or signs of liver damage (yellowing of the skin or eyes, dark urine) — associated with paracetamol overdose

Paracetamol overdose is particularly dangerous because liver damage may not be apparent immediately. If you suspect an overdose, go to A&E straight away even if you feel well.

What Should You Do If You Experience Side Effects?

For mild side effects such as drowsiness or constipation, these usually resolve once the medicine has worn off. Avoid driving or operating machinery if you feel drowsy. Staying well hydrated and eating fibre-rich foods can help manage constipation. If side effects are persistent, troublesome, or unexpected, stop taking the tablets and speak to your pharmacist or GP as soon as possible.

You should also report suspected side effects through the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk — this helps regulators monitor the safety of medicines in real-world use.

Can Migraleve Pink Interact With Other Medicines?

Yes. Migraleve Pink can interact with several other medicines, which is why it's important to tell your pharmacist about everything you are currently taking. Key interactions include other paracetamol-containing products (which can lead to accidental overdose), sedatives and sleeping tablets (which increase drowsiness), warfarin (regular paracetamol use can affect blood clotting), and MAOIs (which should not be taken within 14 days of codeine-containing medicines). Alcohol also significantly increases the sedative effect of codeine and should be avoided.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

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Content last updated: 31 Mar 2025

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