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Lyclear Sensitive 150ml

Lyclear Sensitive 150ml

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  • ✔️ Dimeticone 4% physically suffocates head lice and eggs
  • ✔️ Suitable for sensitive scalps from 6 months old
  • ✔️ No insecticide resistance possible with physical action
  • ✔️ Single 150ml bottle treats multiple family members
  • ✔️ Two-application course clears lice within 7 days

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What Is the Best Head Lice Treatment for Sensitive Skin?

 

Head lice are a common problem across the UK, particularly in school-age children. The NHS estimates that head lice affect millions of children every year, and finding a treatment that is both effective and gentle can feel like a challenge — especially if you or your child has a sensitive scalp. Lyclear Sensitive 150ml is a dimeticone-based lotion designed specifically for those who need a kinder approach. You can explore the full range of head lice treatments at Cured Pharmacy to find the right option for your family.

Unlike older insecticide-based products, Lyclear Sensitive works through a physical rather than chemical mechanism. That means it is less likely to cause irritation and there is no risk of lice developing resistance to it over time — something that has become an increasing concern with some traditional treatments.

 

How Does Lyclear Sensitive Work Against Head Lice?

 

The active ingredient in Lyclear Sensitive is dimeticone 4%, a type of silicone oil. Rather than attacking the nervous system of lice (as insecticides do), dimeticone works by coating the lice and blocking their ability to manage water. This physically immobilises and suffocates them. It also disrupts the eggs (nits), reducing their viability.

  • Dimeticone coats the outer surface of lice, blocking their spiracles (breathing pores)
  • The silicone oil interferes with the louse's ability to excrete water, causing it to die
  • The lotion penetrates the egg casing, reducing the likelihood of hatching
  • Because it is a physical action, lice cannot develop resistance to dimeticone

 

Who Should Use Lyclear Sensitive 150ml?

 

Lyclear Sensitive is suitable for a wide range of people. It is particularly well-suited to those who have previously experienced irritation with insecticide-based treatments, or where there is a known or suspected resistance to permethrin in the local area. The NHS recommends wet combing or dimeticone-based products as first-line options for many households.

  • Adults and children aged 6 months and over
  • People with sensitive or reactive scalps
  • Those who have not responded to permethrin-based treatments
  • Families looking for a fragrance-reduced, gentler formulation

 

How Does Lyclear Sensitive Compare to Other Head Lice Treatments?

 

Feature Lyclear Sensitive 150ml Permethrin-Based Treatments
Active ingredient Dimeticone 4% Permethrin 1%
Mode of action Physical (suffocation) Chemical (neurotoxic to lice)
Resistance risk None — physical action Resistance reported in UK lice populations
Suitable for sensitive skin Yes — formulated for sensitivity Not specifically

 

Is Lyclear Sensitive Suitable for Pregnant or Breastfeeding Women?

 

If you are pregnant or breastfeeding, it is always wise to check with your pharmacist or GP before using any topical treatment. Dimeticone is not absorbed through the skin in significant amounts, which makes it a commonly recommended option during pregnancy — but individual circumstances vary. As a head lice treatment for sensitive skin, Lyclear Sensitive is generally considered one of the more appropriate choices in these situations, though professional guidance is always advisable.

Store Lyclear Sensitive below 25°C, away from direct sunlight and heat sources. Keep the bottle tightly closed when not in use and out of reach of children. If you are also managing other skin concerns, you may find our skin care collection helpful for complementary products.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Lyclear Sensitive 150ml specifications
Treatment category Head lice (pediculosis capitis)
Mechanism of action Physical suffocation via dimeticone coating
Effective against Head lice (Pediculus humanus capitis) and eggs
Suitable for Adults and children aged 6 months and over
Active ingredient Dimeticone 4%
Pack size 150ml
UK classification General Sale List (GSL) / Pharmacy (P) medicine
Drug class Pediculicide (physical action)
Preparation Topical lotion
Route of administration Topical (scalp and hair)

Specifications of Lyclear Sensitive 150ml

 

What Is Lyclear Sensitive and What Is It Used For?

 

Lyclear Sensitive 150ml is a topical lotion used to treat infestations of head lice (Pediculus humanus capitis) in adults and children aged 6 months and over. It contains dimeticone 4% as its active ingredient — a silicone-based compound that physically immobilises and kills lice without relying on chemical insecticides. Head lice are tiny insects that live on the scalp and feed on blood. They spread easily through direct head-to-head contact and are particularly common in primary school-aged children, though anyone can be affected.

This product is specifically formulated for those with sensitive scalps or skin, making it a suitable alternative where standard treatments have caused irritation or where insecticide resistance is suspected. It does not prevent head lice infestation and should only be used when live lice have been confirmed by detection combing.

 

What Do You Need to Know Before Using Lyclear Sensitive?

 

Before applying Lyclear Sensitive, read the following carefully. Do not use this product if any of the contraindications below apply to you.

Do not use Lyclear Sensitive if you:

  • Are allergic to dimeticone or any other ingredient in the formulation
  • Have an infant under 6 months of age (use only under medical supervision)
  • Have broken, infected, or severely inflamed skin on the scalp
  • Have a known skin condition such as eczema or psoriasis affecting the scalp — seek advice from your pharmacist first

Warnings and precautions:

  • Keep away from eyes — if contact occurs, rinse thoroughly with water
  • Highly flammable — keep away from naked flames, cigarettes, and heat sources during application and while the hair is wet with the product
  • Do not inhale the lotion
  • If you are pregnant or breastfeeding, consult your pharmacist or GP before use
  • Not for internal use

Drug interactions:

  • No significant drug interactions are currently known for topical dimeticone
  • Avoid using other hair or scalp products simultaneously unless advised by a healthcare professional

 

How Should You Use Lyclear Sensitive?

 

Always follow the instructions provided with the product. The lotion should be applied to dry hair — not wet — to ensure maximum coverage and effectiveness. Here is a step-by-step guide:

  1. Ensure hair is completely dry before starting
  2. Apply Lyclear Sensitive lotion directly to the scalp and work through to the ends of the hair
  3. Make sure all hair is thoroughly coated, paying particular attention to the area behind the ears and at the nape of the neck
  4. Leave the lotion on for a minimum of 8 hours — overnight application is ideal
  5. After the treatment period, wash the hair with a regular shampoo
  6. Use a fine-toothed detection comb to remove dead lice and eggs from the hair
  7. Repeat the full treatment after 7 days to catch any lice that may have hatched from eggs since the first application
Indication Age Group Dose Frequency
Head lice infestation Adults and children 6 months+ Sufficient to coat all hair and scalp Two applications, 7 days apart
Head lice infestation Under 6 months Only under medical supervision As directed by a doctor

If you are looking for additional support products to use alongside treatment, our hair care collection includes a range of complementary options.

 

What Are the Possible Side Effects of Lyclear Sensitive?

 

Like all medicines, Lyclear Sensitive can cause side effects, although not everyone will experience them. Because dimeticone works physically rather than chemically, side effects tend to be mild and localised.

Common side effects:

  • Mild scalp irritation or itching at the application site
  • Temporary redness of the scalp
  • A slight greasy or heavy feeling in the hair during treatment

Less common side effects:

  • Burning or stinging sensation on the scalp
  • Skin rash or contact dermatitis in sensitive individuals
  • Eye irritation if the product accidentally contacts the eyes

If you experience signs of a serious allergic reaction — such as swelling of the face, lips, or throat, difficulty breathing, or a widespread rash — stop using the product immediately and seek urgent medical attention. For children and young people, our baby and toddler section has further guidance on age-appropriate products.

 

How Should You Store Lyclear Sensitive?

 

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Keep the bottle tightly closed when not in use
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the bottle
  • Do not dispose of via wastewater or household waste — return unused medicine to your pharmacist for safe disposal

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Lyclear Sensitive 150ml online in the UK?

You can buy Lyclear Sensitive 150ml directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for £14.99. It is available without a prescription as an over-the-counter medicine. Browse our full head lice treatment range for more options.

How does Lyclear Sensitive work to kill head lice?

Lyclear Sensitive contains dimeticone 4%, a silicone-based oil that physically coats head lice and blocks their ability to breathe and manage water. This suffocates the lice without using chemical insecticides, meaning there is no risk of resistance developing. It also disrupts the viability of lice eggs (nits).

How do I use Lyclear Sensitive step by step?

Apply the lotion to completely dry hair, coating the scalp and all hair from root to tip. Leave it on for at least 8 hours — overnight is ideal — then wash off with regular shampoo and comb through with a fine-toothed nit comb. Repeat the full process after 7 days to treat any lice that have hatched since the first application.

Is Lyclear Sensitive safe for children?

Yes, Lyclear Sensitive is suitable for adults and children aged 6 months and over. For children under 6 months, treatment should only be carried out under the supervision of a doctor or healthcare professional. Always keep the lotion away from children's eyes and mouth during application.

What is the correct dose of Lyclear Sensitive?

There is no fixed volume dose — you should apply enough lotion to thoroughly coat all of the hair and scalp. Two applications are required in total: one on day one and a second application seven days later. Do not apply more frequently than directed.

What are the side effects of Lyclear Sensitive?

Side effects are uncommon but can include mild scalp irritation, temporary redness, or a slight stinging sensation at the application site. Serious allergic reactions are rare but possible — if you notice swelling, difficulty breathing, or a widespread rash, stop use immediately and seek medical attention.

How long does Lyclear Sensitive take to work?

Lyclear Sensitive begins working on contact with lice, but the lotion must remain on the hair for a minimum of 8 hours to be fully effective. After washing off, you should comb through the hair to remove dead lice and eggs. A second treatment after 7 days ensures any newly hatched lice are also eliminated.

What is the difference between Lyclear Sensitive and Lyclear Creme Rinse?

Lyclear Sensitive uses dimeticone, which works by physically suffocating lice — making it ideal for sensitive scalps and situations where insecticide resistance is a concern. Lyclear Creme Rinse contains permethrin, a chemical insecticide that targets the nervous system of lice. Resistance to permethrin has been reported in some UK lice populations, which is one reason dimeticone-based products are increasingly recommended.

Can I use Lyclear Sensitive if I am pregnant or breastfeeding?

Dimeticone is not significantly absorbed through the skin, which makes Lyclear Sensitive one of the more commonly considered options during pregnancy and breastfeeding. However, you should always speak to your pharmacist or GP before using any medicine during pregnancy or while breastfeeding, as individual circumstances vary.

Can lice become resistant to Lyclear Sensitive?

No — because dimeticone works through a purely physical mechanism (suffocation), lice cannot develop resistance to it in the way they can with chemical insecticides like permethrin. This makes it a reliable option even in areas where insecticide-resistant lice have been identified.

Who is eligible to use Lyclear Sensitive?

Lyclear Sensitive is suitable for most adults and children aged 6 months and over who have a confirmed head lice infestation. It is particularly appropriate for those with sensitive or reactive scalps, those who have not responded to permethrin-based treatments, and those seeking a fragrance-reduced option. Speak to a pharmacist if you are unsure whether it is right for you.

What happens if Lyclear Sensitive does not work after two treatments?

If live lice are still detected after completing both applications (day one and day seven), you should speak to your pharmacist. They may recommend an alternative treatment with a different active ingredient or mode of action. You can explore other options in our head lice collection.

How do I know if my child actually has head lice?

The most reliable way to confirm a head lice infestation is detection combing — using a fine-toothed nit comb on wet, conditioned hair and checking the comb after each stroke. Simply seeing a child scratch their head is not enough to confirm lice, as itching can have other causes. The NHS recommends detection combing as the gold standard for diagnosis.

Are there any alternatives to Lyclear Sensitive for head lice?

Yes — alternatives include other dimeticone-based products, isopropyl myristate-based treatments, and wet combing (the Bug Busting method) using a fine-toothed comb and conditioner. Permethrin-based treatments are also available but may be less effective where resistance is present. Your pharmacist can help you choose the most appropriate option based on your circumstances.

How should I store Lyclear Sensitive at home?

Store Lyclear Sensitive below 25°C in a cool, dry place away from direct sunlight and heat sources. Keep the bottle tightly closed when not in use and out of the reach of children. Do not use the product after the expiry date printed on the packaging, and return any unused medicine to your pharmacist for safe disposal.

How Should You Use Lyclear Sensitive?

Lyclear Sensitive should always be applied to completely dry hair — not damp or wet. Applying to dry hair ensures the dimeticone lotion coats the hair shaft and scalp effectively, giving it the best chance of working. Follow these steps carefully each time you use the product.

What Is the Correct Dose of Lyclear Sensitive?

There is no fixed volume — you should use enough lotion to coat all of the hair and scalp completely. The amount needed will vary depending on hair length and thickness. Two full applications are always required, regardless of hair length.

When Is the Best Time to Use Lyclear Sensitive?

The best time to apply Lyclear Sensitive is in the evening, just before bed. This allows the lotion to remain on the hair for the full 8-hour minimum contact time overnight, without disrupting daily activities. Applying at bedtime also makes it easier to manage for children, who may find it uncomfortable to have the lotion in their hair during the day.

Make sure the hair is completely dry before application — do not apply after bathing or swimming. If the hair gets wet during the treatment period, the effectiveness of the lotion may be reduced.

How Long Can You Use Lyclear Sensitive For?

Lyclear Sensitive is intended for short-term use only — specifically two applications, seven days apart, to treat a single episode of head lice infestation. It should not be used continuously or as a preventative measure. If live lice are still detected after completing both treatments, speak to your pharmacist before applying any further doses, as they may recommend an alternative product.

If head lice recur after a successful course of treatment, this is most likely due to re-infestation from close contact rather than treatment failure. Check all household members and close contacts, and treat simultaneously where live lice are confirmed.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Lyclear Sensitive?

Most people tolerate Lyclear Sensitive well, and side effects are generally mild when they do occur. Because dimeticone works through a physical rather than chemical mechanism, it tends to cause fewer adverse reactions than insecticide-based alternatives. That said, any topical product applied to the scalp can occasionally cause localised reactions.

  • Mild itching or irritation of the scalp at the application site
  • Temporary redness of the skin on the scalp
  • A greasy or heavy sensation in the hair during the treatment period

What Are the Less Common Side Effects of Lyclear Sensitive?

Less commonly, some people may experience slightly more noticeable reactions, particularly those with pre-existing scalp sensitivity or skin conditions. These effects are usually temporary and resolve once the product is washed off.

  • Burning or stinging sensation on the scalp
  • Contact dermatitis — a localised skin rash caused by sensitivity to an ingredient
  • Eye irritation if the lotion accidentally contacts the eyes — rinse thoroughly with water if this occurs
  • Dryness or flaking of the scalp after washing off the product

What Are the Serious Side Effects of Lyclear Sensitive?

Serious side effects are rare but can occur. A severe allergic reaction (anaphylaxis) is possible with any medicine, though it is uncommon with topical dimeticone. You should be aware of the signs and act quickly if they appear.

Stop using Lyclear Sensitive immediately and seek urgent medical attention if you experience any of the following: swelling of the face, lips, tongue, or throat; difficulty breathing or swallowing; a widespread skin rash or hives; dizziness or feeling faint. Do not wait to see if symptoms improve on their own — call 999 or go to your nearest A&E.

What Should You Do If You Experience Side Effects?

If you notice mild irritation or redness, wash the product off with shampoo and cool water. Allow the scalp to settle before considering whether to retry the treatment. If symptoms persist or worsen after washing off the product, contact your pharmacist or GP for advice. You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Do not apply any other scalp or hair products to the affected area until the irritation has fully resolved. If you have a known skin condition such as eczema or psoriasis, always seek pharmacist advice before using Lyclear Sensitive.

Can Lyclear Sensitive Interact With Other Medicines?

No significant drug interactions are currently known for topically applied dimeticone. Because the active ingredient is not meaningfully absorbed through the skin, systemic interactions with oral or injectable medicines are not expected. However, you should avoid applying other hair treatments, scalp oils, or medicated shampoos at the same time as Lyclear Sensitive, as these could dilute the lotion or interfere with its ability to coat the lice effectively.

If you are using any prescribed scalp treatments or have been advised by a doctor to use a specific hair product, check with your pharmacist before using Lyclear Sensitive alongside it.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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