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Lyclear Express Shampoo 200ml

Lyclear Express Shampoo 200ml

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  • ✔️ Kills head lice and eggs in just 15 minutes
  • ✔️ Contains dimethicone 4% — no chemical resistance risk
  • ✔️ Suitable for adults and children aged 2 and over
  • ✔️ 200ml bottle provides multiple full-course treatments
  • ✔️ Effective against lice and nits in a single shampoo step

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What Is Lyclear Express Head Lice Shampoo?

 

Head lice are one of the most common childhood nuisances in the UK, affecting millions of families every year. If you've spotted the telltale signs — an itchy scalp, tiny eggs clinging to hair shafts, or live lice moving through the hair — you'll want something that works quickly and reliably. Head lice shampoo like Lyclear Express Shampoo 200ml offers a straightforward, mess-free solution that fits into a busy family routine. Available from our head lice treatment collection, this product is designed to tackle infestations in a single 15-minute application.

Lyclear Express Shampoo contains dimethicone 4% as its active ingredient. Unlike older insecticide-based treatments, dimethicone works through a physical rather than chemical mechanism, which means there are no concerns about lice developing resistance over time. It is available over the counter without a prescription, making it easy to access when you need it most.

 

How Does Lyclear Express Shampoo Work?

 

The science behind Lyclear Express is straightforward. Dimethicone is a silicone-based compound that coats the louse's body and blocks its ability to manage water, ultimately causing it to die. It also penetrates the egg casing, targeting nits before they hatch. Here's how the mechanism works step by step:

  • Dimethicone coats the outer surface of lice and eggs on contact.
  • It disrupts the louse's ability to excrete water, leading to death by osmotic stress.
  • The shampoo formulation allows even distribution from root to tip.
  • A 15-minute contact time is sufficient to achieve efficacy against live lice and eggs.

Because this is a physical mode of action rather than a neurotoxic one, it remains effective even where chemical resistance has been reported in local lice populations.

 

Who Should Use Lyclear Express Shampoo?

 

This product is suitable for most people who have a confirmed or suspected head lice infestation. It is particularly useful for families who want a quick treatment that doesn't require lengthy application times. That said, it's worth knowing who it's most appropriate for before you buy.

  • Children aged 2 years and over (with adult supervision).
  • Adults with an active head lice infestation.
  • Individuals who have not responded to wet combing alone.
  • Those seeking a non-insecticide treatment option.

It is not recommended for children under 2 years of age without specific medical advice. If you are pregnant or breastfeeding, speak to your pharmacist or GP before use.

 

How Does Lyclear Express Shampoo Compare to Other Lice Treatments?

 

Feature Lyclear Express Shampoo Wet Combing (No Product)
Active ingredient Dimethicone 4% None
Application time 15 minutes 30–45 minutes per session
Kills eggs (nits)? Yes Removes but does not kill
Resistance risk None (physical action) Not applicable

 

Is Lyclear Express Shampoo Safe to Store at Home?

 

Yes. Lyclear Express Shampoo should be stored below 25°C, away from direct heat and sunlight. Keep it out of reach of children when not in use. The 200ml bottle provides enough product for multiple treatments, which is particularly useful if more than one family member needs treating at the same time. If you're also managing other skin or hair concerns, you might find our hair care collection helpful for complementary products.

Do not use the product after the expiry date printed on the packaging. If you notice any change in colour, consistency, or smell, do not use it and contact your pharmacist for advice.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Lyclear Express Shampoo 200ml specifications
Treatment category Head lice treatment
Active ingredient Dimethicone 4%
Mechanism of action Physical suffocation of lice and eggs via silicone coating
Effective against Head lice (Pediculus humanus capitis) and eggs (nits)
Suitable for Adults and children aged 2 years and over
Pack size 200ml
UK classification General Sale List (GSL) / Pharmacy (P) medicine
Drug class Pediculicide (physical action)
Preparation Shampoo
Route of administration Topical (scalp)

Specifications of Lyclear Express Shampoo 200ml

 

What Is Lyclear Express Shampoo and What Is It Used For?

 

Lyclear Express Shampoo 200ml is a topical treatment used to eliminate head lice infestations in adults and children aged 2 years and over. It contains dimethicone 4%, a silicone-based active ingredient that physically suffocates lice and their eggs rather than relying on chemical insecticides. Head lice are tiny parasitic insects that live on the scalp and feed on blood. They spread through close head-to-head contact and are particularly common among school-age children, though anyone can be affected. The NHS advises that head lice cannot jump or fly — they can only crawl from one head to another during direct contact.

This head lice shampoo is used for the treatment of an active infestation. It is not intended as a preventative measure. Two treatments are required — the first application and a repeat seven days later — to ensure any lice that hatch from eggs after the initial treatment are also eliminated.

 

What Do You Need to Know Before Using Lyclear Express Shampoo?

 

Before using this product, read the following carefully. There are certain situations where you should not use Lyclear Express Shampoo or should seek advice first.

Do not use if:

  • You are allergic to dimethicone or any other ingredient in the formulation.
  • The person being treated is under 2 years of age (without medical advice).
  • The scalp has open wounds, broken skin, or a secondary infection.
  • You have a known sensitivity to silicone-based products.

Speak to your pharmacist or GP before use if:

  • You are pregnant or breastfeeding.
  • The person being treated has asthma or a respiratory condition (avoid inhaling the product).
  • You are treating a very young child or an elderly person with a sensitive scalp.

Known drug interactions:

  • No significant drug interactions have been identified for topical dimethicone.
  • Avoid using alongside other scalp treatments at the same time unless advised by a pharmacist.

 

How Should You Use Lyclear Express Shampoo?

 

Always follow the instructions in the patient information leaflet supplied with the product. The steps below reflect standard guidance for this type of head lice shampoo treatment.

  1. Check that the hair is dry before applying — do not wet the hair first.
  2. Apply a generous amount of shampoo directly to the dry scalp and hair.
  3. Massage thoroughly from roots to tips, ensuring all hair is covered.
  4. Leave the shampoo on for 15 minutes — set a timer to be sure.
  5. Rinse the hair thoroughly with warm water.
  6. While the hair is still damp, comb through with a fine-tooth nit comb to remove dead lice and eggs.
  7. Repeat the entire process after 7 days.
Indication Age Group Dose Frequency
Head lice infestation Adults and children aged 2+ Sufficient to cover all hair and scalp Two applications, 7 days apart
Head lice infestation Children under 2 Only under medical supervision As directed by a healthcare professional

If you are also managing other hair or scalp conditions alongside a lice infestation, browse our skin care collection for complementary products that may help soothe an irritated scalp.

 

What Are the Possible Side Effects of Lyclear Express Shampoo?

 

Like all medicines, Lyclear Express Shampoo can cause side effects, although not everyone experiences them. Dimethicone is generally well tolerated when applied topically.

Common side effects:

  • Mild scalp irritation or itching after application.
  • Temporary redness of the scalp or surrounding skin.
  • A slight burning or tingling sensation during the 15-minute contact period.

Less common side effects:

  • Skin rash or hives at the site of application.
  • Eye irritation if the product accidentally contacts the eyes — rinse immediately with water.
  • Allergic contact dermatitis in individuals with silicone sensitivity.

If you experience signs of a serious allergic reaction — such as swelling of the face, lips, or throat, difficulty breathing, or a widespread rash — stop using the product immediately and seek emergency medical attention. This type of reaction is rare but requires prompt action.

 

How Should You Store Lyclear Express Shampoo?

 

Correct storage helps maintain the product's effectiveness and safety throughout its shelf life. For families managing recurring infestations, it's worth keeping a bottle accessible but stored safely. You might also find it useful to explore our baby and toddler collection for other family health essentials.

  • Store below 25°C in a cool, dry place.
  • Keep away from direct sunlight and sources of heat.
  • Keep the bottle tightly closed when not in use.
  • Store out of sight and reach of children.
  • Do not use after the expiry date printed on the bottle or carton.
  • Do not dispose of medicines via wastewater or household waste — return unused product to your pharmacy.

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Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Lyclear Express Shampoo online in the UK?

You can buy Lyclear Express Shampoo 200ml directly from Cured Pharmacy online for £15.99 with fast UK delivery. It is available without a prescription as an over-the-counter treatment. Browse our full head lice collection for additional treatment options and nit combs.

How does Lyclear Express Shampoo work in the body?

Lyclear Express Shampoo contains dimethicone 4%, a silicone-based compound that physically coats the surface of head lice and their eggs. This coating blocks the louse's ability to regulate water, causing it to die through osmotic stress rather than chemical poisoning. Because it works physically rather than chemically, there is no risk of lice developing resistance to it over time.

How do I use Lyclear Express Shampoo step by step?

Apply the shampoo to completely dry hair, massaging it thoroughly from roots to tips until all hair is covered. Leave it on for exactly 15 minutes, then rinse with warm water and comb through with a fine-tooth nit comb while the hair is still damp. Repeat the full process seven days after the first treatment to catch any lice that may have hatched from surviving eggs.

How long do I leave Lyclear Express Shampoo on my hair?

The recommended contact time for Lyclear Express Shampoo is 15 minutes from the point of application. Setting a timer is a good idea to make sure you don't rinse it off too early, as the full contact time is needed for the dimethicone to work effectively. Do not leave it on significantly longer than directed unless a pharmacist advises otherwise.

Can children use Lyclear Express Shampoo?

Yes, Lyclear Express Shampoo is suitable for children aged 2 years and over when used under adult supervision. For children under 2 years of age, you should always seek advice from a pharmacist or GP before using any head lice treatment. Keep the shampoo away from children's eyes during application and rinse immediately with water if contact occurs.

What are the side effects of Lyclear Express Shampoo?

Most people tolerate Lyclear Express Shampoo well, but some may experience mild scalp irritation, temporary redness, or a slight tingling sensation during the 15-minute contact period. Less commonly, skin rash or eye irritation can occur if the product contacts the eyes — rinse immediately with water if this happens. Stop use and seek medical advice if you notice signs of an allergic reaction such as swelling, hives, or difficulty breathing.

How many treatments of Lyclear Express Shampoo do I need?

Two treatments are required for a complete course: the first application on day one, followed by a second treatment exactly seven days later. The second application is essential because it targets any lice that may have hatched from eggs that survived the first treatment. Skipping the second treatment significantly increases the risk of the infestation returning.

Is Lyclear Express Shampoo safe to use during pregnancy?

If you are pregnant or breastfeeding, you should speak to your pharmacist or GP before using Lyclear Express Shampoo, even though it is applied topically and systemic absorption is considered minimal. Your healthcare professional can advise whether wet combing alone or another treatment option may be more appropriate during pregnancy. Do not use any head lice treatment during pregnancy without seeking advice first.

What are alternatives to Lyclear Express Shampoo for head lice?

Alternatives include other dimethicone-based products such as Hedrin Once Liquid Gel, as well as isopropyl myristate-based treatments like Full Marks Solution. Wet combing with a fine-tooth nit comb every few days over a two-week period is also recommended by the NHS as an effective non-chemical option. Your pharmacist can help you choose the most suitable treatment based on the age of the person being treated and any previous treatments used.

Does Lyclear Express Shampoo kill nits (eggs) as well as live lice?

Yes, Lyclear Express Shampoo is formulated to target both live head lice and their eggs (nits) by coating them with dimethicone. However, because no treatment can guarantee 100% egg kill in a single application, the second treatment seven days later is specifically designed to eliminate any lice that hatch after the first application. Using a nit comb after each treatment helps physically remove dead lice and loosened eggs from the hair.

Can I use Lyclear Express Shampoo on coloured or chemically treated hair?

Lyclear Express Shampoo is generally considered safe to use on coloured or chemically treated hair, as dimethicone is not known to strip hair colour or damage chemically processed hair. However, if you have any concerns about your specific hair type or treatment, it is worth checking with your pharmacist before use. Always perform a patch test on a small area of skin if you have a history of scalp sensitivity.

How do I know if the head lice treatment has worked?

After completing both treatments and combing sessions, check the hair carefully with a fine-tooth nit comb under good lighting — ideally over a white surface so you can spot any lice or eggs. If you find live lice more than two days after the second treatment, the infestation may not have been fully cleared and you should speak to your pharmacist about trying a different product. The NHS recommends checking all household members and treating those who are also infested at the same time.

How long does a head lice infestation last without treatment?

Without treatment, a head lice infestation will not resolve on its own — lice will continue to breed and spread as long as they remain on the scalp. A single female louse can lay up to 8 eggs per day, so infestations can worsen quickly if left untreated. Starting treatment as soon as an infestation is confirmed is the most effective way to prevent it spreading to other household members or close contacts.

Can I use Lyclear Express Shampoo as a preventative treatment?

No — Lyclear Express Shampoo is intended for the treatment of an active head lice infestation, not as a preventative measure. Using it on hair that does not have lice is unnecessary and not recommended. If your child is frequently exposed to lice at school, the NHS advises regular detection combing as the most practical way to catch an infestation early rather than using treatments prophylactically.

What is the latest research on dimethicone for head lice treatment?

Dimethicone-based treatments have been studied extensively and are well established as effective, resistance-free options for head lice. Clinical evidence supports their use as a first-line treatment, particularly in areas where resistance to older insecticide-based products such as permethrin has been reported. The NHS and NICE both recognise physical-action treatments like dimethicone as appropriate options for managing head lice in the UK. You can also explore our hair care collection for supporting products.

How Should You Use Lyclear Express Shampoo?

Using Lyclear Express Shampoo correctly is essential to getting the best results from your treatment. Always apply it to dry hair — this is different from a regular shampoo and an important step that many people miss. Follow these numbered steps carefully each time you treat:

Avoid getting the shampoo in the eyes. If contact occurs, rinse immediately with plenty of water. Adult supervision is required when treating children.

What Is the Correct Dose of Lyclear Express Shampoo?

There is no fixed measured dose for Lyclear Express Shampoo — you should use enough product to coat all of the hair and scalp thoroughly. The amount needed will vary depending on hair length and thickness. The 200ml bottle is sufficient for multiple treatments, even for longer or thicker hair.

When Is the Best Time to Use Lyclear Express Shampoo?

There is no specific time of day that is clinically required for applying Lyclear Express Shampoo, but many people find it easiest to use in the evening when there is more time to complete the full process without rushing. Choosing a time when the person being treated can sit still for the 15-minute contact period makes the process much smoother, particularly with younger children. Treating all affected household members on the same day is also recommended to prevent re-infestation.

How Long Can You Use Lyclear Express Shampoo For?

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What Are the Most Common Side Effects of Lyclear Express Shampoo?

Lyclear Express Shampoo is generally well tolerated, and most people complete their treatment without any significant problems. Because dimethicone works through a physical rather than chemical mechanism, the side effect profile is relatively mild compared to older insecticide-based treatments. That said, some people do experience localised reactions on the scalp or surrounding skin.

  • Mild scalp itching or irritation after application.
  • Temporary redness of the scalp or skin around the hairline.
  • A slight burning or tingling sensation during the 15-minute contact period.
  • Temporary dryness of the scalp after rinsing.

What Are the Less Common Side Effects of Lyclear Express Shampoo?

Less commonly, some individuals may experience more noticeable skin reactions, particularly those with a history of sensitive skin or scalp conditions. These reactions are not typical but are worth being aware of before you start treatment.

  • Skin rash or hives at the site of application.
  • Eye irritation if the product accidentally contacts the eyes.
  • Allergic contact dermatitis in individuals with silicone sensitivity.
  • Localised swelling of the scalp or surrounding skin.

What Are the Serious Side Effects of Lyclear Express Shampoo?

Serious side effects from Lyclear Express Shampoo are rare but can occur in individuals who have an allergic reaction to dimethicone or another ingredient in the formulation. If you notice any of the following after applying the product, stop use immediately and seek urgent medical attention. Do not wait to see if symptoms improve on their own.

  • Swelling of the face, lips, tongue, or throat.
  • Difficulty breathing or swallowing.
  • A widespread skin rash or severe hives.
  • Dizziness or feeling faint.

What Should You Do If You Experience Side Effects?

For mild side effects such as scalp irritation or temporary redness, rinsing the hair thoroughly with cool water usually provides relief. Avoid scratching the scalp, as this can worsen irritation and increase the risk of a secondary skin infection. If symptoms persist beyond 24 hours or worsen after rinsing, contact your pharmacist for advice. For serious reactions, call 999 or go to your nearest A&E department immediately.

Can Lyclear Express Shampoo Interact With Other Medicines?

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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