Skip to product information
1 of 1

  • Images are for illustration purposes only

Loperamide 2mg Capsules 30 capsules

Loperamide 2mg Capsules 30 capsules

  • 1. Ozempic®️-equivalent therapy now available for weight management
  • 2. Average weight loss of 17%, with 1 in 3 patients achieving over 20%
  • 3. May help reduce osteoarthritis-related pain
  • 4. Wegovy®️ is not expected to impact the effectiveness of oral contraceptives
  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Relieves acute diarrhoea symptoms within one to three hours
  • ✔️ Slows bowel movement to reduce loose stool frequency
  • ✔️ Suitable for adults and young people aged 12 and over
  • ✔️ Effective for traveller's diarrhoea when taken promptly
  • ✔️ 30-capsule pack provides multiple doses for extended relief

Price Checker

Regular price £3.25
Sale price £3.25
Sale Sold out
  • Lowest price guarantee
  • Includes FREE private prescription
View full details

 

What Are Loperamide 2mg Capsules and How Do They Help?

 

Loperamide 2mg capsules are a widely used, over-the-counter antidiarrhoeal medicine that can help bring fast relief when you're dealing with an unexpected bout of acute diarrhoea. Each capsule contains 2mg of loperamide hydrochloride as the active ingredient. Available without a prescription, they're a practical option to keep to hand — whether you're at home or heading off on a trip. You can browse our full range of treatments in our diarrhoea collection if you'd like to compare your options.

Diarrhoea can strike at any time and, beyond the discomfort, it can leave you feeling drained and dehydrated. The NHS notes that most cases in adults clear up within a few days, but that doesn't make the experience any less disruptive. Loperamide works to slow things down and give your body a chance to recover.

 

How Does Loperamide Work to Stop Diarrhoea?

 

Loperamide belongs to a class of medicines called antidiarrhoeals. It acts locally on the gut rather than being absorbed into the bloodstream in significant amounts, which is part of what makes it suitable for short-term use without a prescription.

  • Binds to opioid receptors in the wall of the intestine
  • Slows down the muscular contractions (peristalsis) that move contents through the bowel
  • Allows more time for water and electrolytes to be reabsorbed from the gut
  • Results in firmer, less frequent stools

It does not treat the underlying cause of diarrhoea — for example, if a bacterial infection is responsible, you may need separate treatment. But for most cases of acute, non-specific diarrhoea, it provides effective symptomatic relief.

 

Who Is Loperamide Suitable For?

 

These capsules are suitable for a broad range of adults and older teenagers. That said, it's not right for everyone, so it's worth checking before you start.

  • Adults aged 18 and over experiencing acute diarrhoea
  • Young people aged 12–17 (under pharmacist or medical guidance)
  • Travellers dealing with traveller's diarrhoea
  • People who need short-term symptom control while staying hydrated

It is not suitable for children under 12, and should not be used if you have bloody or black stools, a high fever alongside diarrhoea, or if you have been diagnosed with conditions such as acute ulcerative colitis. If you're unsure whether loperamide is right for you, speak to your pharmacist before purchasing.

 

How Do Loperamide 2mg Capsules Compare to Other Diarrhoea Treatments?

 

Feature Loperamide 2mg Capsules Oral Rehydration Salts (ORS)
Primary action Slows bowel movement Replaces lost fluids and electrolytes
Suitable for children under 12 No Yes
Treats dehydration No Yes
Available OTC Yes Yes

 

How Should You Store Loperamide 2mg Capsules?

 

Store your capsules below 25°C in a dry place, away from direct sunlight. Keep them out of reach and sight of children at all times. Do not use after the expiry date printed on the packaging. If you're travelling, it's worth keeping them in their original blister pack to protect them from moisture — particularly useful if you're heading somewhere warm and humid where traveller's diarrhoea is a risk. If you're managing other digestive concerns alongside diarrhoea, you might also find our IBS and cramps collection helpful.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Loperamide 2mg Capsules 30 Capsules specifications
Treatment category Antidiarrhoeal
Mechanism of action Opioid receptor agonist (gut-selective); slows intestinal motility
Effective for Acute diarrhoea, traveller's diarrhoea
Suitable for Adults and children aged 12 and over
Active ingredient Loperamide hydrochloride 2mg
Pack size 30 capsules
Strength 2mg per capsule
UK classification General Sale List (GSL) / Pharmacy (P) medicine
Drug class Antidiarrhoeal — opioid receptor agonist
Preparation Hard capsule
Route of administration Oral

Specifications of Loperamide 2mg Capsules 30 Capsules

 

What Is Loperamide and What Is It Used For?

 

Loperamide hydrochloride 2mg capsules are an antidiarrhoeal medicine used to relieve the symptoms of acute diarrhoea in adults and young people aged 12 and over. Acute diarrhoea is defined as the sudden onset of loose or watery stools, often accompanied by stomach cramps, urgency, and bloating. It can be caused by a viral or bacterial infection, food intolerance, anxiety, or changes in diet — particularly when travelling abroad.

The NHS advises that most cases of diarrhoea in adults resolve within two to four days without treatment, but loperamide can help manage symptoms in the meantime, allowing you to carry on with daily life more comfortably. It is not a cure for the underlying cause — it simply slows the bowel to reduce the frequency and urgency of loose stools.

 

What Do You Need to Know Before Using Loperamide Capsules?

 

Before taking loperamide, it's important to check whether it is appropriate for your situation. Do not take these capsules if any of the following apply to you:

  • You are allergic to loperamide hydrochloride or any other ingredient in the capsule
  • You have bloody or black, tarry stools
  • You have a high fever alongside diarrhoea
  • You have been diagnosed with acute ulcerative colitis or pseudomembranous colitis
  • You are under 12 years of age
  • You are pregnant (especially in the first trimester) — seek medical advice first
  • You are breastfeeding — speak to your pharmacist or GP before use

The following medicines may interact with loperamide and should be discussed with your pharmacist or doctor before use:

  • Quinidine (used for heart rhythm problems) — may increase loperamide levels in the blood
  • Ritonavir (an HIV medicine) — may increase loperamide plasma concentration
  • Itraconazole (an antifungal) — may affect how loperamide is processed by the body
  • Other medicines that slow gut motility — additive effects possible

 

How Should You Use Loperamide 2mg Capsules?

 

Always follow the dosage instructions on the packaging or as directed by your pharmacist. Swallow capsules whole with a glass of water. Do not chew them. It's also important to stay well hydrated while you have diarrhoea — the NHS recommends drinking plenty of fluids to prevent dehydration, particularly water or oral rehydration solutions.

  1. Take 2 capsules (4mg) as your starting dose
  2. After each subsequent loose stool, take 1 capsule (2mg)
  3. Do not take more than 8 capsules (16mg) in any 24-hour period
  4. Do not use for more than 48 hours without seeking medical advice
  5. If symptoms persist beyond 48 hours, consult your GP
Indication Age Group Starting Dose Maximum Daily Dose
Acute diarrhoea Adults (18+) 4mg (2 capsules) 16mg (8 capsules)
Acute diarrhoea 12–17 years 2mg (1 capsule) 8mg (4 capsules) — seek pharmacist advice
Under 12 years Children Not suitable — do not use

 

What Are the Possible Side Effects of Loperamide Capsules?

 

Like all medicines, loperamide can cause side effects, although not everyone experiences them. Most side effects are mild and tend to resolve once you stop taking the medicine.

Common side effects:

  • Constipation
  • Abdominal cramps or discomfort
  • Nausea
  • Flatulence (wind)
  • Headache

Less common side effects:

  • Dizziness or drowsiness
  • Dry mouth
  • Skin rash or itching
  • Vomiting
  • Bloating or abdominal distension

Stop taking loperamide and seek medical attention immediately if you experience a serious allergic reaction (difficulty breathing, swelling of the face or throat, severe skin rash), or if you develop an irregular heartbeat. Taking more than the recommended dose can cause serious heart rhythm problems — always stick to the stated dose. If you're also managing stomach discomfort or indigestion alongside diarrhoea, our indigestion collection may have suitable products to support you.

 

How Should You Store Loperamide 2mg Capsules?

 

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and moisture
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the blister pack or carton
  • Do not dispose of medicines via wastewater or household waste — return unused capsules to your pharmacy

If you're travelling and want to be prepared for a range of health concerns on the go, take a look at our travel health collection for a range of useful OTC products.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy loperamide 2mg capsules online in the UK?

You can buy loperamide 2mg capsules directly from Cured Pharmacy, a GPhC-registered online pharmacy in the UK. No prescription is needed — they are available as an over-the-counter medicine. Simply add them to your basket and complete your order online for convenient home delivery. You can also browse our full diarrhoea collection for related products.

How does loperamide work in the body?

Loperamide binds to opioid receptors in the wall of the intestine, slowing down the muscular contractions that push contents through the bowel. This gives the gut more time to absorb water and electrolytes, resulting in firmer and less frequent stools. It acts locally in the gut and does not significantly enter the bloodstream at recommended doses.

How do I use loperamide 2mg capsules step by step?

Start by taking 2 capsules (4mg) as your initial dose. After each subsequent loose stool, take 1 further capsule (2mg). Do not exceed 8 capsules (16mg) in any 24-hour period, and do not continue for more than 48 hours without speaking to a healthcare professional.

What is the correct dose of loperamide for adults?

The standard adult starting dose is 4mg (two 2mg capsules), followed by 2mg after each loose stool. The maximum dose is 16mg (eight capsules) per day. Always read the patient information leaflet and do not exceed the stated dose under any circumstances.

How quickly does loperamide start working?

Most people begin to notice a reduction in the frequency of loose stools within one to three hours of taking the first dose. Significant improvement is usually seen within 24 to 48 hours. If there is no improvement after 48 hours, stop taking loperamide and consult your GP.

What are the common side effects of loperamide capsules?

The most commonly reported side effects include constipation, abdominal cramps, nausea, flatulence, and headache. These are generally mild and short-lived. If side effects are severe or persistent, stop taking the capsules and speak to your pharmacist or GP.

How do I manage side effects of loperamide?

If you develop constipation after taking loperamide, stop taking it and ensure you are drinking plenty of fluids. For mild nausea, taking the capsule with a small amount of food may help. If you experience dizziness, avoid driving or operating machinery until the feeling passes.

Who should not take loperamide 2mg capsules?

Loperamide is not suitable for children under 12, people with bloody or black stools, those with a high fever alongside diarrhoea, or anyone with acute ulcerative colitis or pseudomembranous colitis. People who are pregnant (especially in the first trimester) or breastfeeding should seek medical advice before use.

Can I take loperamide if I am pregnant or breastfeeding?

Loperamide is generally not recommended during the first trimester of pregnancy, and caution is advised throughout pregnancy. Small amounts may pass into breast milk, so breastfeeding mothers should speak to their GP or pharmacist before taking it. Your healthcare professional can advise on the safest option for your situation.

What happens if I miss a dose of loperamide?

Loperamide is taken as needed after each loose stool rather than on a fixed schedule, so a missed dose is less of a concern than with regular medicines. Simply take the next dose after your next loose stool, and do not double up. Never take more than 8 capsules in 24 hours.

What are alternatives to loperamide for diarrhoea?

Oral rehydration salts (ORS) are an important complementary treatment that replaces fluids and electrolytes lost during diarrhoea — they are suitable for all ages including children. Bismuth subsalicylate is another option used in some countries, though it is less commonly available in the UK. Your pharmacist can help you choose the most appropriate treatment for your circumstances. You can also explore our sickness and nausea collection for related products.

Can loperamide be used for traveller's diarrhoea?

Yes, loperamide is commonly used to manage traveller's diarrhoea, which is typically caused by consuming contaminated food or water abroad. It helps reduce the frequency of loose stools so you can continue travelling more comfortably. However, if you develop a high fever or bloody stools, stop taking it and seek medical attention promptly.

How long can you take loperamide for?

Loperamide should not be used for more than 48 hours for acute diarrhoea without medical advice. If your symptoms have not improved within this time, you should consult your GP as there may be an underlying cause that requires investigation or a different treatment. Long-term use without medical supervision is not recommended.

Does loperamide interact with any other medicines?

Yes, loperamide can interact with certain medicines including quinidine, ritonavir, and itraconazole, which may increase the amount of loperamide in your bloodstream and raise the risk of side effects. Always tell your pharmacist about any other medicines you are taking before starting loperamide. This includes prescription medicines, herbal remedies, and supplements.

What are the latest guidelines on using loperamide safely?

The MHRA has issued guidance warning that taking loperamide at doses higher than recommended can cause serious heart rhythm problems, including QT prolongation and cardiac arrest. Always stick to the dose on the label — never exceed 16mg in 24 hours for self-treatment. The NHS and BNF both advise limiting use to 48 hours for acute diarrhoea without medical review.

How Should You Use Loperamide 2mg Capsules?

Swallow each capsule whole with a full glass of water — do not crush or chew them. It's important to keep drinking plenty of fluids while you have diarrhoea to avoid dehydration, as loperamide reduces symptoms but does not replace lost fluids or electrolytes.

What Is the Correct Dose of Loperamide 2mg Capsules?

The dose varies depending on your age. Never exceed the maximum daily dose, as taking too much loperamide can cause serious side effects including heart rhythm problems. Always follow the guidance below or as directed by your pharmacist.

When Is the Best Time to Use Loperamide 2mg Capsules?

Take your first dose as soon as acute diarrhoea begins — there is no specific time of day requirement, as dosing is triggered by symptoms rather than a fixed schedule. Taking it promptly at the onset of symptoms gives it the best chance to reduce the frequency and urgency of loose stools before they become disruptive to your day.

If you are travelling and concerned about traveller's diarrhoea, it is sensible to pack loperamide in your travel kit so it is available the moment symptoms start. Do not take it as a preventative measure before symptoms occur.

How Long Can You Use Loperamide 2mg Capsules For?

For acute diarrhoea, loperamide should not be used for more than 48 hours without seeking medical advice. Most people find their symptoms resolve well within this window. If diarrhoea continues beyond 48 hours, or if you develop a fever, blood in your stools, or severe abdominal pain, stop taking loperamide and contact your GP promptly.

Long-term or regular use of loperamide without medical supervision is not appropriate for self-treatment. If you find yourself needing it frequently, speak to your doctor to investigate any underlying cause.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)

What Are the Most Common Side Effects of Loperamide 2mg Capsules?

Most people tolerate loperamide well at the recommended dose, but some do experience side effects. Common side effects tend to be mild and usually resolve once you stop taking the medicine.

  • Constipation — the most frequently reported effect, as loperamide slows bowel movement
  • Abdominal cramps or discomfort
  • Nausea
  • Flatulence (wind)
  • Headache

What Are the Less Common Side Effects of Loperamide Capsules?

A smaller number of people may experience the following side effects. These are less likely at the recommended dose but worth being aware of before you start treatment.

  • Dizziness or drowsiness
  • Dry mouth
  • Vomiting
  • Bloating or abdominal distension
  • Skin rash or itching
  • Fatigue

What Are the Serious Side Effects of Loperamide Capsules?

Serious side effects are rare when loperamide is taken at the recommended dose. However, taking more than the stated maximum dose significantly increases the risk of serious cardiac events. The MHRA has warned that excessive doses of loperamide can cause QT interval prolongation, ventricular arrhythmias, and in rare cases, cardiac arrest.

Stop taking loperamide immediately and seek urgent medical attention if you experience any of the following:

  • Irregular or rapid heartbeat (palpitations)
  • Fainting or loss of consciousness
  • Severe allergic reaction — swelling of the face, lips, or throat, difficulty breathing, or a widespread skin rash
  • Severe abdominal bloating or pain (possible sign of ileus)

What Should You Do If You Experience Side Effects of Loperamide?

For mild side effects such as constipation or nausea, stop taking loperamide and ensure you are drinking plenty of fluids. Constipation will usually resolve naturally once the medicine is out of your system. If you feel dizzy, avoid driving or operating heavy machinery until the feeling passes.

You can report suspected side effects of any medicine in the UK through the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk. This helps regulators monitor the safety of medicines in real-world use.

Can Loperamide Interact With Other Medicines?

Yes. Loperamide can interact with several medicines that affect how it is broken down in the body. Quinidine, ritonavir, and itraconazole can all increase the concentration of loperamide in the bloodstream, raising the risk of cardiac side effects. Other medicines that slow gut motility may have additive effects when taken alongside loperamide.

Always tell your pharmacist or doctor about every medicine you are currently taking — including prescription drugs, over-the-counter products, herbal remedies, and supplements — before starting loperamide.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

We’re a safe and
regulated UK service

Registered Pharmacy Badge

Lowest Price Guarantee

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

100% discreet packaging

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

Agent

Need help?
Talk to our friendly experts now

How our service works

Service Setup

Service setup

Discreet Packaging

Discreet packaging

Express Delivery

Express delivery