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Infacol Colic Relief Simeticone pack

Infacol Colic Relief Simeticone pack

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  • ✔️ Relieves infant colic, trapped wind, and griping pain
  • ✔️ Simeticone works gently without entering the bloodstream
  • ✔️ Suitable for babies from birth, breast or bottle-fed
  • ✔️ Sugar-free and alcohol-free oral suspension
  • ✔️ Consistent use builds effect for lasting colic relief

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Is Infacol Colic Relief Right for Your Baby?

 

If your baby cries inconsolably after feeds, draws their knees up, or seems to be in real discomfort from trapped wind, you are not alone. Infant colic affects roughly one in five babies in the UK, and it can be exhausting for the whole family. Infacol colic relief is one of the most widely used over-the-counter remedies for this, and for good reason — it has a straightforward mechanism, a clean safety profile, and it is suitable from birth. You can find it alongside other trusted products in our baby and toddler range at Cured Pharmacy.

Infacol contains simeticone 40mg/ml as its active ingredient. It is a sugar-free, alcohol-free oral suspension presented in a convenient dropper bottle, making it easy to give to even very young infants. Each 55ml bottle provides multiple doses, and at just £4.99 it represents genuinely good value for parents dealing with a distressing but common problem.

 

How Does Infacol Colic Relief Work in Your Baby's Gut?

 

Simeticone is an antifoaming agent. It does not get absorbed into the bloodstream — it works entirely within the gut, which is part of what makes it so well suited to use in infants. Here is what happens after each dose:

  • Simeticone reduces the surface tension of small gas bubbles trapped in the intestinal contents.
  • These tiny bubbles coalesce into fewer, larger bubbles.
  • Larger bubbles are far easier for your baby to pass — either as wind or through a bowel movement.
  • This process helps relieve the pressure and cramping that causes colic-related crying.

Because simeticone is not absorbed systemically, it does not carry the same risks as medicines that enter the bloodstream. It simply does its job locally in the digestive tract and passes out of the body naturally.

 

Who Is Infacol Colic Relief Suitable For?

 

Infacol is designed specifically for infants experiencing colic, griping pain, or trapped wind. It is suitable from birth, which makes it one of the few options available to parents of very young newborns. That said, it is always worth speaking to your health visitor or GP if you are unsure whether colic is the cause of your baby's distress — other conditions can sometimes present similarly.

  • Babies from birth onwards experiencing colic symptoms.
  • Infants with trapped wind causing discomfort after feeds.
  • Babies with griping pain associated with feeding.
  • Breastfed and bottle-fed babies alike — Infacol works regardless of feeding method.

It is not recommended for premature infants without prior medical advice. If your baby was born prematurely, please consult your neonatal team or GP before using any over-the-counter medicine.

 

How Does Infacol Compare to Other Infant Colic Drops?

 

Feature Infacol Colic Relief Dentinox Colic Drops
Active ingredient Simeticone 40mg/ml Simeticone 21mg/2.5ml
When to give Before each feed Added to each feed
Suitable from birth Yes Yes
Sugar-free Yes Yes

 

How Should You Store Infacol and Is It Clinically Suitable?

 

Infacol colic relief should be stored below 25°C and must not be refrigerated, as cold temperatures can affect the consistency of the suspension. Keep the bottle tightly closed when not in use, and always store it out of the reach and sight of children. The dropper should be cleaned after each use to prevent contamination.

From a clinical standpoint, simeticone has a well-established safety record in infants. It is not absorbed into the body, has no known drug interactions at recommended doses, and does not affect the absorption of other medicines your baby may be taking. If your baby has any diagnosed digestive condition, or if you are giving any other medicines, it is still sensible to check with your pharmacist first. You might also find it helpful to browse our IBS and cramps section for related digestive health products for older family members.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Infacol Colic Relief Simeticone specifications
Treatment category Infant colic, trapped wind, griping pain
Mechanism of action Antifoaming agent — coalesces intestinal gas bubbles for easier passage
Effective for Colic, trapped wind, griping pain in infants
Suitable for Babies from birth onwards
Active ingredient Simeticone 40mg/ml
Pack size 55ml
Strength 40mg/ml
UK classification General Sale List (GSL)
Drug class Antifoaming agent
Preparation Oral suspension
Route of administration Oral

Specifications of Infacol Colic Relief Simeticone

 

What Is Infacol Colic Relief and What Is It Used For?

 

Infacol Colic Relief is an oral suspension containing simeticone 40mg/ml. It is used to relieve the symptoms of infant colic — a condition characterised by prolonged, unexplained crying in otherwise healthy babies, typically occurring in the first few months of life. The NHS describes colic as one of the most common concerns raised by new parents, and while it usually resolves on its own by around three to four months of age, the distress it causes in the meantime is very real.

Infacol is specifically indicated for the relief of griping pain and trapped wind in infants. It is classified as a General Sale List (GSL) medicine in the UK, meaning it can be purchased without a prescription. It is not a cure for colic, but it can meaningfully reduce the discomfort associated with gas build-up in the digestive tract.

 

What Do You Need to Know Before Using Infacol Colic Relief?

 

Before giving Infacol to your baby, it is important to be aware of the following contraindications and precautions:

  • Do not use if your baby is known to be allergic to simeticone or any other ingredient in the formulation.
  • Not recommended for premature infants without prior medical advice.
  • If your baby's symptoms do not improve after one week of use, consult your GP or health visitor.
  • Persistent or severe crying may indicate a condition other than colic — always seek medical advice if you are concerned.
  • Do not use beyond the expiry date printed on the bottle.

In terms of drug interactions, simeticone is not absorbed systemically and has no known clinically significant interactions with other medicines at recommended doses. However, as a precaution:

  • If your baby is receiving any prescribed medicines, check with your pharmacist before starting Infacol.
  • No interactions with common infant medicines (such as vitamin D drops) have been reported.

 

How Should You Use Infacol Colic Relief?

 

Infacol is straightforward to use, but consistency matters. Because simeticone works by accumulating in the gut over time, you are likely to see better results if you give it before every feed rather than just occasionally. Follow these steps each time:

  1. Shake the bottle gently before use.
  2. Remove the dropper cap and draw up the correct dose (0.5ml).
  3. Place the dropper gently into your baby's mouth.
  4. Slowly release the suspension onto the tongue or inside the cheek.
  5. Give the dose immediately before the feed — not during or after.
  6. Replace the dropper cap securely after use and clean the dropper tip.
Age Group Dose Frequency
Babies from birth 0.5ml (20 drops) Before each feed

Do not exceed the stated dose. If you are unsure about how to use the dropper, ask your pharmacist to demonstrate.

 

What Are the Possible Side Effects of Infacol Colic Relief?

 

Infacol is generally very well tolerated in infants. Simeticone is not absorbed into the body, which significantly limits the potential for systemic side effects. That said, as with any medicine, reactions are possible in rare cases.

Common side effects (may affect up to 1 in 10 babies):

  • No commonly reported side effects have been identified at the recommended dose in clinical use.

Less common or rare side effects:

  • Allergic reaction — symptoms may include skin rash, itching, or swelling of the face, lips, or throat.
  • If you notice any signs of an allergic reaction, stop using Infacol immediately and seek urgent medical attention.

If your baby seems more unsettled after starting Infacol, or if you notice any unusual symptoms, stop use and speak to your GP or health visitor. You can also find useful information about digestive discomfort in older children and adults in our indigestion section.

 

How Should You Store Infacol Colic Relief?

 

Correct storage helps maintain the quality and effectiveness of the suspension throughout its shelf life. Follow these guidelines:

  • Store below 25°C — do not refrigerate.
  • Keep the bottle tightly closed when not in use.
  • Store out of the sight and reach of children.
  • Do not use after the expiry date printed on the label.
  • Do not dispose of medicines via wastewater or household waste — return unused medicine to your pharmacist for safe disposal.

If you have any concerns about storage or the appearance of the suspension, speak to your pharmacist before giving it to your baby. For other products relevant to your baby's health and wellbeing, take a look at our vitamins and supplements range, which includes infant vitamin D drops recommended by the NHS for all babies under one year.

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Frequently Asked Questions

Where can I buy Infacol colic relief online in the UK?

You can buy Infacol Colic Relief Simeticone online from Cured Pharmacy for just £4.99, with no prescription required. It is a General Sale List (GSL) medicine, so it is available over the counter. Browse our full baby and toddler range for other infant health essentials.

How does Infacol colic relief work in the body?

Infacol contains simeticone, an antifoaming agent that works entirely within the gut without being absorbed into the bloodstream. It reduces the surface tension of small trapped gas bubbles, causing them to merge into larger bubbles that your baby can pass more easily. This helps relieve the pressure and cramping that causes colic-related crying.

How do I give Infacol to my baby step by step?

Shake the bottle gently, then draw up 0.5ml using the dropper provided. Place the dropper gently into your baby's mouth and slowly release the suspension onto the tongue before the feed begins. Clean the dropper tip after each use and replace the cap securely.

What is the correct dose of Infacol for my baby?

The recommended dose of Infacol for babies from birth is 0.5ml (equivalent to 20 drops) given before each feed. Do not exceed this dose, and always use the dropper supplied with the bottle to measure accurately. If you are unsure, ask your pharmacist for guidance.

How long does Infacol take to work?

Infacol may not produce immediate results — it often takes a few days of consistent use before you notice a meaningful improvement in your baby's symptoms. This is because the effect of simeticone can build up over time with repeated doses before each feed. Stick with it for at least three to five days before deciding whether it is helping.

Can I use Infacol colic relief from birth?

Yes, Infacol is suitable for use from birth in full-term babies. It is one of the few infant colic remedies licensed for use from day one. However, if your baby was born prematurely, always consult your neonatal team or GP before using any over-the-counter medicine.

Are there any side effects of Infacol simeticone drops?

Infacol is generally very well tolerated, and no common side effects have been identified at the recommended dose. Rare allergic reactions are possible — signs include a rash, swelling, or unusual irritability. If you suspect an allergic reaction, stop use immediately and seek medical advice.

Can I use Infacol with a premature baby?

Infacol is not recommended for premature infants without first seeking advice from a doctor or healthcare professional. Premature babies have more complex medical needs, and any medicine — even an OTC product — should be discussed with your neonatal care team first. Always err on the side of caution with premature infants.

What are the alternatives to Infacol for infant colic?

The main alternative simeticone-based product in the UK is Dentinox Colic Drops, which is added to a feed rather than given before it. Some parents also try gripe water, though this works differently and is not suitable for babies under one month. If you are looking for digestive support products for older family members, our IBS and cramps section may be helpful.

Does Infacol work for both breastfed and bottle-fed babies?

Yes, Infacol is suitable for both breastfed and bottle-fed babies. The drops are given directly into the baby's mouth before the feed, regardless of feeding method. There is no need to mix it into a bottle or alter your feeding routine in any other way.

How long can I use Infacol for my baby?

You can continue using Infacol for as long as your baby experiences colic symptoms, which typically resolve naturally by three to four months of age. If symptoms persist beyond this point, or if there is no improvement after one week of use, speak to your GP or health visitor. There is no evidence of harm from longer-term use at the recommended dose.

What happens if I miss a dose of Infacol?

If you forget to give Infacol before a feed, simply give it before the next feed as usual — do not double up the dose to compensate. Consistency is important for best results, but missing the occasional dose is unlikely to cause any harm. Try to build it into your feeding routine so it becomes a habit.

Is Infacol safe to use alongside other baby medicines?

Simeticone has no known clinically significant interactions with other medicines at the recommended dose, as it is not absorbed into the bloodstream. However, if your baby is taking any prescribed medicines, it is always sensible to check with your pharmacist before adding any new product. Your pharmacist can advise on timing and compatibility.

What is the difference between Infacol and gripe water?

Infacol contains simeticone, which works by physically breaking down gas bubbles in the gut. Gripe water typically contains sodium bicarbonate and dill seed oil, and works differently — it is also not suitable for babies under one month old. Infacol is generally considered the more evidence-supported option for trapped wind and colic in young infants.

What are the latest studies on simeticone for infant colic?

Research on simeticone for infant colic has produced mixed results, with some studies showing modest benefit and others showing no significant difference compared to placebo. The NHS acknowledges that no single treatment has been proven to cure colic, but many parents find Infacol helpful in managing symptoms. Speak to your GP or health visitor if you want to discuss the evidence in more detail.

How Should You Use Infacol Colic Relief?

Infacol is given orally using the dropper bottle provided. It is important to give it before each feed — not during or after — so that it is already present in the gut when milk arrives. Follow these steps every time you use it:

Consistency is key. Giving Infacol before every feed — rather than just when symptoms seem bad — gives the best chance of a cumulative effect building up in the gut over time.

What Is the Correct Dose of Infacol Colic Relief?

There is only one recommended dose for Infacol, and it applies to all babies from birth onwards. Always use the dropper supplied with the bottle to measure the dose accurately — do not estimate or use a different measuring device.

Do not give more than 0.5ml per feed. If your baby is having six to eight feeds per day, they will receive six to eight doses — this is normal and within the recommended usage pattern.

When Is the Best Time to Use Infacol Colic Relief?

The best time to give Infacol is immediately before each feed, whether breast or bottle. Giving it before the feed — rather than after — means simeticone is already present in the gut to act on gas bubbles as they form during feeding. Try to make it part of your pre-feed routine so you do not forget.

If your baby is particularly unsettled at certain times of day, such as in the evening (a common pattern with colic), make sure you do not skip the dose before those feeds. Evening feeds are often when colic symptoms are at their worst, so consistency at those times matters most.

How Long Can You Use Infacol Colic Relief For?

Infacol can be used for as long as your baby experiences colic symptoms. Infant colic typically resolves naturally by around three to four months of age, so most parents find they no longer need it after this point. There is no evidence of harm from continued use at the recommended dose beyond this period.

If your baby's symptoms have not improved after one week of consistent use, or if symptoms worsen at any point, stop using Infacol and speak to your GP or health visitor. Persistent crying in infants can occasionally have other causes that need medical assessment.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Infacol Colic Relief?

Infacol is one of the most well-tolerated infant medicines available in the UK. Because simeticone is not absorbed into the bloodstream — it works entirely within the gut — the potential for systemic side effects is extremely low. In clinical use at the recommended dose, no common side effects have been formally identified or reported with any regularity.

  • No commonly reported side effects at the recommended dose of 0.5ml per feed.
  • Simeticone passes through the digestive tract without being absorbed.

This does not mean side effects are impossible, but it does mean that the vast majority of babies tolerate Infacol without any issues at all.

What Are the Less Common Side Effects of Infacol Colic Relief?

While uncommon, some babies may experience a reaction to one of the ingredients in Infacol. The active ingredient simeticone itself is very unlikely to cause problems, but excipients (inactive ingredients) in the formulation could theoretically trigger a response in sensitive individuals.

  • Skin rash or redness.
  • Unusual irritability or increased crying after dosing.
  • Loose stools (very rare and not definitively linked to simeticone).

If you notice any of these symptoms after starting Infacol, stop use and speak to your GP or health visitor before continuing.

What Are the Serious Side Effects of Infacol Colic Relief?

Serious side effects with Infacol are rare but not impossible. The most significant concern is an allergic reaction (hypersensitivity). Although this is uncommon, it is important to know the signs so you can act quickly if it occurs.

  • Swelling of the face, lips, tongue, or throat.
  • Difficulty breathing or swallowing.
  • Sudden onset of severe rash or hives across the body.
  • Collapse or limpness in the baby.

If you observe any of these signs, stop using Infacol immediately and call 999 or take your baby to the nearest A&E department without delay. Do not wait to see if symptoms improve on their own.

What Should You Do If Your Baby Experiences Side Effects?

For mild reactions — such as a slight rash or increased fussiness — stop using Infacol and monitor your baby closely. Most mild reactions resolve quickly once the product is discontinued. Make a note of what you observed and when, as this will help your GP or health visitor assess the situation.

For any serious reaction, seek emergency medical help immediately as described above. You can also report suspected side effects of any medicine to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. Reporting helps improve medicine safety for all patients.

Can Infacol Interact With Other Medicines?

Simeticone has no known clinically significant drug interactions at the recommended dose. Because it is not absorbed into the bloodstream, it does not interfere with the metabolism or action of other medicines your baby may be taking. This includes common infant medicines such as vitamin D drops, paracetamol suspension, or prescribed antibiotics.

That said, if your baby is on any prescribed medication, it is always good practice to mention that you are using Infacol when speaking to your GP or pharmacist. They can confirm there are no concerns specific to your baby's situation. Never assume that because a medicine is available over the counter it is automatically safe to combine with everything else.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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