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Glycerol 2g (12) suppositories for children

Glycerol 2g (12) suppositories for children

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  • ✔️ Provides constipation relief in children within 15–30 minutes
  • ✔️ Gentle rectal action — no systemic absorption in children
  • ✔️ Suitable for children aged 1 year and over
  • ✔️ Each pack contains 12 x 2g suppositories for multiple uses
  • ✔️ Stimulant-free formula — gentler than bisacodyl suppositories

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Are Glycerol Suppositories for Children Right for Your Child?

 

Constipation in children is more common than many parents realise. The NHS estimates that around one in three children in the UK will experience constipation at some point, and it can be distressing for both child and carer. When dietary changes and increased fluid intake haven't done the trick, a short-term laxative can help. Glycerol suppositories for children offer a fast-acting, rectal route to relief — bypassing the digestive system entirely and working directly where the problem is. Each suppository in this pack contains 2g of glycerol, and the pack contains 12 suppositories, making it a practical option to keep at home. You can also browse our Baby and Toddler collection for other products suited to younger children.

This product is available over the counter without a prescription and is priced at just £3.29 for a pack of 12. It's a well-established, trusted option that has been used in paediatric care for decades.

 

How Do Glycerol Suppositories Work in the Body?

 

Glycerol works through two complementary mechanisms when inserted rectally. Understanding how it works can help you feel more confident using it for your child.

  • Osmotic action: Glycerol draws water into the rectum from surrounding tissues, softening the stool and making it easier to pass.
  • Stimulant effect: It mildly irritates the rectal mucosa, which stimulates peristalsis — the muscular contractions that move stool towards the anus.
  • Local lubrication: As the suppository melts at body temperature, it coats the rectal wall, providing a degree of lubrication to ease passage of the stool.
  • Rapid onset: Because it acts locally rather than being absorbed systemically, results typically occur within 15 to 30 minutes of insertion.

Because glycerol acts locally in the rectum, it is not absorbed into the bloodstream in any meaningful quantity. This makes it a particularly suitable choice for children, where systemic exposure to laxative agents is best minimised.

 

Who Should Use These Glycerol Suppositories?

 

These suppositories are designed specifically for children and are suitable for short-term management of constipation. They are particularly useful when a child is uncomfortable, straining, or has not had a bowel movement for several days despite dietary measures. They are not intended for long-term or daily use.

  • Children aged 1 year and over experiencing short-term constipation
  • Children who are unable or unwilling to swallow oral laxatives
  • Children where rapid relief is needed (e.g. before a medical appointment)
  • Situations where dietary fibre and fluid increases have not resolved the problem

Always speak to your GP or pharmacist if your child's constipation is recurrent, if there is blood in the stool, or if your child is in significant pain.

 

How Do Glycerol Suppositories Compare to Oral Laxatives for Children?

 

Feature Glycerol 2g Suppositories (Children) Oral Laxative (e.g. Lactulose)
Route of administration Rectal Oral
Onset of action 15–30 minutes 24–48 hours
Systemic absorption Minimal Variable
Suitable for children who won't swallow medicine Yes No

 

How Should You Store These Suppositories and Are They Clinically Suitable?

 

Store below 25°C in a dry place, away from direct sunlight. Do not refrigerate — cold temperatures can make the suppositories brittle and difficult to insert. Keep out of the reach and sight of children. Check the expiry date on the packaging before use and do not use if the suppository appears discoloured or damaged.

Clinically, glycerol suppositories for children are considered a first-line rectal laxative option in paediatric constipation management. They are free from stimulant laxative ingredients such as bisacodyl, making them gentler on the rectal mucosa. If your child has a history of rectal conditions, inflammatory bowel disease, or has recently had rectal surgery, consult a doctor before use. For broader digestive health support, you may also find our Constipation collection helpful.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Glycerol 2g (12) Suppositories for Children specifications
Treatment category Laxative / Constipation relief
Mechanism of action Osmotic and mild rectal stimulant
Effective Within 15–30 minutes
Suitable for Children aged 1 year and over
Active ingredient Glycerol 2g
Pack sizes 12 suppositories
Strengths 2g per suppository
UK classification General Sale / OTC
Drug class Osmotic laxative
Preparation Suppository
Route of administration Rectal

Specifications of Glycerol 2g (12) Suppositories for Children

 

What Are Glycerol 2g Children's Suppositories and What Are They Used For?

 

Glycerol 2g suppositories for children are a rectal laxative used for the short-term relief of constipation in children aged 1 year and over. Each suppository contains 2g of glycerol as the active ingredient. They are inserted into the rectum, where they dissolve at body temperature and act locally to soften the stool and stimulate a bowel movement. They are not intended to treat the underlying cause of constipation — rather, they provide prompt symptomatic relief while longer-term dietary and lifestyle measures are put in place.

Constipation in children is defined by the NHS as passing fewer than three stools per week, or passing stools that are hard, dry, and difficult or painful to pass. If your child is showing these signs, glycerol suppositories may provide the relief they need quickly and gently.

 

What Do You Need to Know Before Using Glycerol Suppositories in Children?

 

Before using this product, read the following carefully. Do not use these suppositories if any of the following apply to your child:

  • Your child is under 1 year of age (seek GP advice first)
  • Your child has a known allergy or hypersensitivity to glycerol or any other ingredient in the suppository
  • Your child has an acute inflammatory condition of the rectum or anus (e.g. proctitis)
  • Your child has recently had rectal or anal surgery
  • There is unexplained rectal bleeding or blood in the stool
  • Your child has a bowel obstruction or suspected obstruction

Speak to your GP or pharmacist if your child has a history of inflammatory bowel disease, Hirschsprung's disease, or any other chronic gastrointestinal condition before using this product.

Drug interactions: Glycerol suppositories are not known to interact with other medicines when used rectally. However, always inform your pharmacist of any other medicines your child is taking.

  • No clinically significant drug interactions are currently documented for rectal glycerol at this dose

 

How Should You Use Glycerol Suppositories in Children?

 

Follow these steps carefully to ensure safe and effective use. If you are unsure at any point, ask your pharmacist for guidance.

  1. Wash your hands thoroughly with soap and water before and after use.
  2. Remove the suppository from its foil or packaging carefully.
  3. Lay your child on their left side with their knees drawn up towards their chest (the left lateral position).
  4. Gently part the buttocks and insert the suppository, pointed end first, into the rectum — approximately 2–3 cm for a young child.
  5. Hold the buttocks gently together for one to two minutes to prevent the suppository from being expelled before it dissolves.
  6. Encourage your child to remain lying down for a few minutes if possible.
  7. A bowel movement should occur within 15 to 30 minutes.
Indication Age Group Dose Frequency
Short-term constipation relief Children aged 1–12 years One 2g suppository Once daily as needed
Short-term constipation relief Under 1 year Seek GP advice Do not use without medical guidance

Do not use more than one suppository at a time. Do not use on consecutive days for more than a few days without speaking to a doctor or pharmacist. For children with ongoing constipation, your GP may recommend a structured laxative programme alongside dietary changes.

 

What Are the Possible Side Effects of Glycerol Suppositories in Children?

 

Like all medicines, glycerol suppositories can cause side effects, although not everyone will experience them. Because glycerol acts locally in the rectum, systemic side effects are very unlikely.

Common side effects:

  • Mild rectal irritation or a burning sensation after insertion
  • A feeling of urgency to open the bowels
  • Mild abdominal cramping or discomfort

Less common side effects:

  • Rectal discomfort lasting beyond the bowel movement
  • Diarrhoea if the suppository produces a very loose stool
  • Hypersensitivity reactions (very rare) — stop use immediately if your child develops a rash, swelling, or difficulty breathing and seek emergency medical help

If your child experiences rectal bleeding, significant pain, or the suppository has no effect after 30 minutes, do not repeat the dose — contact your GP or pharmacist. You can also find further digestive health products in our IBS and Cramps collection if your child has broader gastrointestinal symptoms.

 

How Should You Store Glycerol Suppositories for Children?

 

  • Store below 25°C in a cool, dry place
  • Do not refrigerate — cold temperatures can make suppositories brittle
  • Keep away from direct sunlight and heat sources
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the packaging
  • Do not use if the suppository appears cracked, discoloured, or damaged
  • Dispose of unused suppositories safely — return to your local pharmacy for disposal

For more information on managing your child's health at home, explore our First Aid collection for a range of useful products to keep in your family medicine cabinet.

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Frequently Asked Questions

Where can I buy glycerol suppositories for children online in the UK?

You can buy Glycerol 2g suppositories for children directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £3.29 per pack of 12. No prescription is needed as this is an over-the-counter medicine. Simply add to your basket and your order will be dispatched promptly to your door.

How do glycerol suppositories work in a child's body?

Glycerol acts as both an osmotic agent and a mild rectal stimulant. It draws water into the rectum to soften the stool while also gently stimulating the rectal muscles to contract, encouraging a bowel movement. Because it works locally rather than being absorbed into the bloodstream, it is considered a gentle option for children.

How do I insert a glycerol suppository into a child step by step?

Wash your hands, then lay your child on their left side with knees drawn up. Gently insert the suppository pointed end first into the rectum, approximately 2–3 cm deep. Hold the buttocks together for one to two minutes to prevent expulsion, and encourage your child to stay still for a few minutes while the suppository dissolves.

What is the correct dose of glycerol suppositories for children?

The recommended dose is one 2g suppository for children aged 1 year and over, used as a single dose when needed. Do not use more than one suppository at a time, and do not use on consecutive days for more than a few days without speaking to a pharmacist or GP. For children under 1 year, always seek medical advice before use.

How quickly do glycerol suppositories work in children?

Most children will experience a bowel movement within 15 to 30 minutes of the suppository being inserted. This makes glycerol suppositories one of the fastest-acting laxative options available without a prescription. If there is no effect after 30 minutes, do not repeat the dose — contact your pharmacist or GP instead.

Are glycerol suppositories safe for toddlers and babies?

Glycerol 2g suppositories are suitable for children aged 1 year and over. For babies under 1 year, you should always consult your GP or health visitor before using any laxative, including glycerol suppositories. Constipation in very young infants can sometimes indicate an underlying condition that needs medical assessment. You can browse our Baby and Toddler collection for other age-appropriate products.

What are the side effects of glycerol suppositories in children?

Side effects are uncommon but can include mild rectal irritation, a burning sensation after insertion, a feeling of urgency, or mild abdominal cramping. Serious side effects such as rectal bleeding or allergic reactions are very rare. If your child experiences any of these, stop use immediately and seek medical advice.

How do I manage side effects of glycerol suppositories in my child?

Mild rectal irritation usually resolves on its own once the bowel movement has occurred. Ensuring your child is in a comfortable position during insertion and not forcing the suppository can help minimise discomfort. If side effects are persistent or your child is distressed, contact your pharmacist or GP for further guidance.

Who is eligible to use glycerol suppositories for children?

These suppositories are suitable for children aged 1 year and over who are experiencing short-term constipation. They are particularly useful for children who cannot or will not swallow oral laxatives. Children with rectal conditions, inflammatory bowel disease, or a history of rectal surgery should only use this product under medical supervision.

What happens if the suppository comes out before it dissolves?

If the suppository is expelled before it has had time to dissolve — usually within the first minute or two — it may not have had sufficient time to work. Hold the buttocks gently together for at least one to two minutes after insertion to help prevent this. If it is expelled immediately, wait and try again later, or speak to your pharmacist for advice.

What are the alternatives to glycerol suppositories for children?

Alternatives include oral osmotic laxatives such as lactulose or macrogol (e.g. Movicol Paediatric Plain), which are commonly recommended by GPs for childhood constipation. Dietary changes — increasing fibre, fluids, and physical activity — are also important first steps. Browse our Constipation collection for a range of laxative options.

How long can children use glycerol suppositories for?

Glycerol suppositories are intended for short-term use only — typically no more than a few days at a time. If your child's constipation persists beyond this, it is important to speak to your GP, as ongoing constipation in children may require a structured treatment plan including dietary advice and longer-term laxative therapy. Prolonged use of any laxative without medical supervision is not recommended.

Can glycerol suppositories be used alongside other medicines?

No clinically significant drug interactions are currently documented for rectal glycerol at this dose. However, always inform your pharmacist of any other medicines your child is taking, including prescription medicines, vitamins, and supplements. If your child is on any medication that affects bowel function, seek medical advice before use.

What is the best time to use glycerol suppositories in children?

There is no single "best" time, but many parents find it easiest to use suppositories after a meal, as eating naturally stimulates bowel activity (the gastrocolic reflex), which may enhance the effect. Choosing a time when your child is calm and cooperative will also make the process easier for both of you.

What does the latest research say about glycerol suppositories for children?

Glycerol suppositories have been used in paediatric practice for many decades and remain a recognised option in clinical guidelines for short-term childhood constipation. The NHS and NICE both acknowledge rectal laxatives as appropriate for acute constipation relief in children when oral options are not suitable or have not worked. They are not considered a long-term solution and should be used alongside dietary and lifestyle measures.

How Should You Use Glycerol 2g Suppositories for Children?

Using a suppository for the first time can feel daunting, but with the right technique it is straightforward and quick. Always wash your hands thoroughly before and after handling the suppository. Follow these steps carefully to ensure your child is comfortable and the suppository works effectively.

If your child is distressed or the suppository cannot be inserted comfortably, do not force it. Speak to your pharmacist or GP for further guidance.

What Is the Correct Dose of Glycerol Suppositories for Children?

The dose depends on your child's age. Always use the lowest effective dose and do not exceed the recommended amount. The table below summarises the dosing guidance for this product.

Never use more than one suppository at a time. If one dose does not produce a result, do not repeat immediately — wait and seek advice from your pharmacist or GP before trying again.

When Is the Best Time to Use Glycerol Suppositories for Children?

There is no fixed time of day that is clinically required, but many parents find it helpful to use the suppository after a meal. Eating naturally stimulates bowel activity through the gastrocolic reflex, which may complement the action of the suppository. Choosing a calm moment when your child is relaxed and cooperative will also make the process easier and more comfortable for everyone involved.

Avoid using the suppository immediately before bedtime if possible, as your child will need to be awake and able to use the toilet within 15 to 30 minutes of insertion.

How Long Can You Use Glycerol Suppositories for Children For?

These suppositories are intended for short-term use only. They should not be used on consecutive days for more than a few days without seeking medical advice. If your child's constipation does not resolve, or if it keeps returning, this may indicate an underlying issue that needs proper assessment by a GP. Long-term constipation in children is often managed with a structured programme including dietary changes, increased fluid intake, and sometimes a prescribed laxative regimen.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Glycerol Suppositories for Children?

Most children tolerate glycerol suppositories well, and side effects are generally mild and short-lived. Because glycerol acts locally in the rectum rather than being absorbed into the bloodstream, systemic side effects are very unlikely. The most commonly reported effects are related to local rectal stimulation.

  • Mild rectal irritation or a warm, burning sensation after insertion
  • A sudden urge to open the bowels (this is the intended effect)
  • Mild abdominal cramping or a feeling of pressure in the lower abdomen

These effects are usually brief and resolve once the bowel movement has occurred. They are not a reason to stop using the suppository unless they are severe or your child is very distressed.

What Are the Less Common Side Effects of Glycerol Suppositories for Children?

Less commonly, some children may experience the following after using a glycerol suppository. These are not dangerous in most cases but are worth being aware of.

  • Rectal discomfort that persists beyond the bowel movement
  • Loose stools or mild diarrhoea if the suppository produces a very watery result
  • Difficulty retaining the suppository before it dissolves, leading to reduced effectiveness

If your child regularly experiences loose stools after using this product, consider whether a lower-stimulation approach — such as dietary changes — might be more appropriate. Speak to your pharmacist for advice.

What Are the Serious Side Effects of Glycerol Suppositories for Children?

Serious side effects are rare but important to know about. Stop using the suppository immediately and seek urgent medical attention if your child experiences any of the following:

  • Rectal bleeding or blood in the stool
  • Severe abdominal pain that does not resolve after the bowel movement
  • Signs of an allergic reaction — including skin rash, swelling of the face or throat, or difficulty breathing
  • No bowel movement after 30 minutes combined with increasing abdominal pain

These symptoms may indicate a more serious underlying condition and require prompt medical assessment.

What Should You Do If Your Child Experiences Side Effects?

For mild side effects such as rectal irritation or brief cramping, no specific treatment is usually needed — they will resolve on their own. Ensure your child is comfortable and has access to the toilet promptly after insertion. If side effects are more troublesome, or if you are concerned about your child's reaction, contact your pharmacist or GP for advice. Do not repeat the dose if the first suppository caused significant discomfort.

You can report suspected side effects of any medicine in the UK through the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Glycerol Suppositories Interact With Other Medicines?

No clinically significant drug interactions are currently documented for rectal glycerol at the 2g dose used in children's suppositories. Because the medicine acts locally in the rectum and is not meaningfully absorbed into the bloodstream, interactions with systemic medicines are considered very unlikely. However, always tell your pharmacist about any other medicines your child is taking — including prescription medicines, over-the-counter products, and supplements — before using this product.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

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Content last updated: 31 Mar 2025

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