Skip to product information
1 of 1

  • Images are for illustration purposes only

Galpharm Diarrhoea Relief 2mg

Galpharm Diarrhoea Relief 2mg

  • 1. Ozempic®️-equivalent therapy now available for weight management
  • 2. Average weight loss of 17%, with 1 in 3 patients achieving over 20%
  • 3. May help reduce osteoarthritis-related pain
  • 4. Wegovy®️ is not expected to impact the effectiveness of oral contraceptives
  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Relieves acute diarrhoea with loperamide hydrochloride 2mg
  • ✔️ Reduces loose stool frequency within one to three hours
  • ✔️ Suitable for adults and children aged 12 and over
  • ✔️ Generic equivalent of Imodium Original at a lower price
  • ✔️ Compact capsule format — easy to carry when travelling

Price Checker

Regular price £2.19
Sale price £2.19
Sale Sold out
  • Lowest price guarantee
  • Includes FREE private prescription
View full details

 

What Are Galpharm Diarrhoea Relief 2mg Loperamide Capsules?

 

Diarrhoea can strike at the most inconvenient times — and when it does, you want something that works quickly and reliably. Galpharm Diarrhoea Relief 2mg capsules contain loperamide hydrochloride, a well-established active ingredient used to treat acute diarrhoea in adults and children aged 12 and over. Each capsule delivers a 2mg dose of loperamide, helping to reduce the frequency of loose stools and restore normal bowel function. You can browse our full range of diarrhoea treatments if you'd like to compare options before buying.

Acute diarrhoea — the sudden onset of loose or watery stools — is extremely common and is usually caused by a viral or bacterial infection, food intolerance, or stress. According to the NHS, most cases resolve on their own within a few days, but medicines like loperamide can help manage symptoms in the meantime, particularly when you need to get on with daily life.

 

How Does Galpharm Diarrhoea Relief 2mg Work in the Body?

 

Loperamide belongs to a class of medicines called opioid receptor agonists. It acts locally on the mu-opioid receptors in the wall of the large intestine, rather than crossing into the central nervous system in meaningful amounts at therapeutic doses. This targeted action is what makes it effective without causing the sedative effects associated with other opioids.

  • Slows the muscular contractions (peristalsis) of the intestinal wall, reducing how quickly contents move through the bowel
  • Increases the time available for water and electrolytes to be reabsorbed from the gut back into the body
  • Reduces the volume and frequency of loose stools
  • Increases anal sphincter tone, which can help reduce urgency

The result? Firmer, less frequent stools — usually within one to three hours of the first dose.

 

Who Is Galpharm Diarrhoea Relief 2mg Suitable For?

 

This product is designed for adults and young people aged 12 and over who are experiencing acute, short-term diarrhoea. It is particularly useful when symptoms are disruptive to daily activities, travel, or work. If you're heading abroad and want to be prepared, it's worth checking our travel health range for additional essentials.

  • Adults aged 18 and over with acute diarrhoea
  • Adolescents aged 12–17 (under adult supervision)
  • Travellers experiencing traveller's diarrhoea
  • People who need rapid symptom relief to manage daily activities

It is not suitable for children under 12, and should not be used without medical advice during pregnancy or breastfeeding.

 

How Does Galpharm Diarrhoea Relief Compare to Imodium Original?

 

Feature Galpharm Diarrhoea Relief 2mg Imodium Original 2mg
Active ingredient Loperamide hydrochloride 2mg Loperamide hydrochloride 2mg
Form Capsule Capsule
Price £2.19 Typically £3.50–£5.00
Suitable age 12 years and over 12 years and over

 

Is Galpharm Diarrhoea Relief 2mg Safe to Store at Home?

 

Yes — loperamide 2mg capsules are straightforward to store. Keep them in a cool, dry place below 25°C, away from direct sunlight and out of the reach and sight of children. Do not use the product after the expiry date printed on the packaging. If you're managing other digestive symptoms alongside diarrhoea, such as bloating or cramping, you might also find our IBS and cramps collection helpful.

Always check the packaging for the expiry date before use, and dispose of any unused capsules safely — your local pharmacy can help with this.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Galpharm Diarrhoea Relief 2mg specifications
Treatment category Antidiarrhoeal
Active ingredient Loperamide hydrochloride 2mg
Mechanism of action Opioid receptor agonist — slows intestinal motility
Suitable for Adults and children aged 12 and over
Strengths 2mg per capsule
UK classification General Sale List (GSL)
Drug class Opioid receptor agonist (peripheral)
Preparation Hard capsule
Route of administration Oral

Specifications of Galpharm Diarrhoea Relief 2mg

 

What Is Galpharm Diarrhoea Relief 2mg and What Is It Used For?

 

Galpharm Diarrhoea Relief 2mg capsules are an over-the-counter antidiarrhoeal medicine containing loperamide hydrochloride. They are used to treat acute diarrhoea — sudden episodes of loose, watery stools that occur more frequently than normal. The NHS defines diarrhoea as passing loose or watery stools three or more times a day. This product helps reduce the frequency and urgency of those episodes, giving your body time to recover.

It may also be used for the symptomatic relief of chronic diarrhoea in adults, though this should only be done under medical supervision. It is not a cure for the underlying cause of diarrhoea — it manages the symptoms while your body fights off the cause.

 

What Do You Need to Know Before Using Galpharm Diarrhoea Relief 2mg?

 

Before taking this medicine, it's important to check whether it is appropriate for you. Do not take Galpharm Diarrhoea Relief 2mg if any of the following apply:

  • You are under 12 years of age
  • You have a known allergy to loperamide hydrochloride or any other ingredient in the capsule
  • You have ulcerative colitis, Crohn's disease, or any other inflammatory bowel condition
  • Your diarrhoea is accompanied by blood or mucus in the stool
  • You have antibiotic-associated diarrhoea (e.g. following a course of antibiotics)
  • You have a high fever alongside diarrhoea
  • You are pregnant or breastfeeding — seek medical advice first
  • You have liver disease — loperamide is metabolised by the liver

The following medicines may interact with loperamide. Always tell your pharmacist or doctor what you are taking:

  • Quinidine — may increase loperamide blood levels
  • Ritonavir (used in HIV treatment) — may increase loperamide plasma concentrations
  • Itraconazole — may affect how loperamide is broken down
  • Other medicines that slow gut motility — additive effects possible

 

How Should You Use Galpharm Diarrhoea Relief 2mg Correctly?

 

Always read the patient information leaflet supplied with the product before use. Take the capsules orally with a glass of water. It is also important to stay well hydrated during any episode of diarrhoea — the NHS recommends drinking plenty of fluids to replace those lost. You might also consider oral rehydration sachets alongside this treatment.

  1. Take two capsules (4mg) as the initial dose
  2. After each subsequent loose stool, take one additional capsule (2mg)
  3. Do not exceed 8 capsules (16mg) in any 24-hour period
  4. Do not use for longer than 48 hours without seeking medical advice
  5. Swallow capsules whole with water — do not chew or crush
Age Group Initial Dose Subsequent Dose Maximum Daily Dose
Adults (18+) 2 capsules (4mg) 1 capsule (2mg) after each loose stool 8 capsules (16mg)
Children 12–17 1 capsule (2mg) 1 capsule (2mg) after each loose stool 6 capsules (12mg)
Under 12 Not suitable — do not use

 

What Are the Possible Side Effects of Galpharm Diarrhoea Relief 2mg?

 

Like all medicines, loperamide can cause side effects, although not everyone experiences them. If you develop any serious symptoms — such as severe abdominal bloating, a distended stomach, or signs of an allergic reaction — stop taking the medicine and seek medical attention immediately. You can also find information about managing digestive discomfort in our indigestion range.

Common side effects (may affect up to 1 in 10 people):

  • Constipation
  • Flatulence (wind)
  • Nausea
  • Abdominal cramps or discomfort
  • Headache

Less common side effects (may affect up to 1 in 100 people):

  • Dizziness or drowsiness
  • Dry mouth
  • Skin rash or itching
  • Vomiting
  • Abdominal bloating

 

How Should You Store Galpharm Diarrhoea Relief 2mg Safely?

 

Correct storage helps maintain the effectiveness and safety of this medicine. If you're building a home medicine cabinet, our first aid collection has everything you might need alongside this product.

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and moisture
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the packaging
  • Do not dispose of medicines via wastewater or household waste — return unused capsules to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Galpharm Diarrhoea Relief 2mg online in the UK?

You can buy Galpharm Diarrhoea Relief 2mg directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available without a prescription as an over-the-counter medicine. Browse our full diarrhoea treatments collection for more options.

How does loperamide 2mg work in the body?

Loperamide acts on opioid receptors in the gut wall, slowing down intestinal contractions so that more water is reabsorbed from the bowel. This reduces the frequency and looseness of stools. It works locally in the gut and does not significantly affect the central nervous system at recommended doses.

How do I use Galpharm Diarrhoea Relief 2mg step by step?

Adults should take two capsules (4mg) as the first dose, then one capsule (2mg) after each subsequent loose stool. Do not exceed eight capsules in 24 hours. Swallow capsules whole with a full glass of water and stay well hydrated throughout.

What is the maximum dose of Galpharm Diarrhoea Relief 2mg in 24 hours?

The maximum dose for adults is eight capsules (16mg) in any 24-hour period. For adolescents aged 12 to 17, the maximum is six capsules (12mg) per day. Never exceed these limits, and do not use for more than 48 hours without speaking to a pharmacist or doctor.

How long does loperamide take to work?

Most people notice a reduction in the frequency of loose stools within one to three hours of taking the first dose. Significant improvement is usually seen within 24 hours. If symptoms have not improved after 48 hours, stop use and seek medical advice.

What are the side effects of Galpharm Diarrhoea Relief 2mg?

Common side effects include constipation, flatulence, nausea, abdominal cramps, and headache. Less commonly, you may experience dizziness, dry mouth, or a skin rash. If you develop severe abdominal bloating or signs of an allergic reaction, stop taking the medicine and seek medical attention immediately.

Who should not take Galpharm Diarrhoea Relief 2mg?

This product is not suitable for children under 12, people with inflammatory bowel conditions such as ulcerative colitis or Crohn's disease, or those with blood or mucus in their stools. It should also be avoided if you have antibiotic-associated diarrhoea or a high fever alongside your symptoms. Always read the label carefully before use.

Can I take Galpharm Diarrhoea Relief 2mg while pregnant?

You should not take loperamide during pregnancy without first speaking to your doctor or midwife. The safety of loperamide in pregnancy has not been fully established, and medical guidance is needed before use. Your GP or pharmacist can advise on safer alternatives if appropriate.

Can I take Galpharm Diarrhoea Relief 2mg while breastfeeding?

Small amounts of loperamide may pass into breast milk, so it is advisable to seek medical advice before using this product if you are breastfeeding. Your pharmacist or GP can help you weigh up the risks and benefits. Do not self-medicate without professional guidance in this situation.

What happens if I miss a dose of Galpharm Diarrhoea Relief 2mg?

Because this medicine is taken as needed after each loose stool rather than on a fixed schedule, a missed dose is less of a concern than with regular medicines. Simply take one capsule the next time you pass a loose stool, and continue as directed. Do not double up doses to compensate.

Does loperamide interact with any other medicines?

Yes — loperamide can interact with quinidine, ritonavir, and itraconazole, all of which may increase loperamide levels in the blood. Always tell your pharmacist about any other medicines, supplements, or herbal remedies you are taking before starting this product. If you are on multiple medications, a pharmacist review is a good idea.

What are the alternatives to Galpharm Diarrhoea Relief 2mg?

Alternatives include other loperamide-containing products such as Imodium Original, or oral rehydration solutions like Dioralyte to replace lost fluids and electrolytes. For those with associated nausea, our sickness and nausea range may also be helpful. Speak to your pharmacist for personalised advice.

How long can you use Galpharm Diarrhoea Relief 2mg for?

This product should not be used for more than 48 hours for acute diarrhoea without seeking medical advice. If symptoms persist beyond two days, or worsen at any point, you should consult a GP. Prolonged use without medical supervision is not recommended.

Is Galpharm Diarrhoea Relief 2mg the same as Imodium?

Yes — both products contain the same active ingredient, loperamide hydrochloride 2mg, in the same capsule form and at the same dose. Galpharm Diarrhoea Relief is a generic equivalent of Imodium Original and works in exactly the same way. The key difference is price — Galpharm is typically more affordable.

What are the latest findings on loperamide safety?

Regulatory bodies including the MHRA have issued guidance highlighting the risk of serious cardiac events when loperamide is taken in doses far exceeding the recommended amount. At the doses stated on the packaging for acute diarrhoea, loperamide is considered safe and well-tolerated for short-term use. Always stick to the recommended dose and duration.

How Should You Use Galpharm Diarrhoea Relief 2mg?

Galpharm Diarrhoea Relief 2mg capsules are taken orally with a full glass of water. It is important to swallow the capsules whole — do not chew, crush, or open them. Staying well hydrated is essential during any episode of diarrhoea, so drink plenty of clear fluids alongside this medicine.

Follow these steps for correct use:

What Is the Correct Dose of Galpharm Diarrhoea Relief 2mg?

The dose varies depending on your age. Always follow the instructions on the packaging or as directed by your pharmacist. Never exceed the stated maximum daily dose, as taking too much loperamide can cause serious side effects.

When Is the Best Time to Use Galpharm Diarrhoea Relief 2mg?

Take the first dose as soon as acute diarrhoea begins — there is no specific time of day requirement. Because subsequent doses are taken after each loose stool rather than on a fixed schedule, timing is guided by your symptoms rather than the clock. If you are taking this medicine before travel or a situation where access to a toilet may be limited, take the initial dose at least one hour before you need to leave.

Always take capsules with a full glass of water, and avoid taking them on a completely empty stomach if you find this causes nausea.

How Long Can You Use Galpharm Diarrhoea Relief 2mg For?

For acute diarrhoea, this product should not be used for more than 48 hours without seeking medical advice. Most episodes of acute diarrhoea resolve within one to two days with appropriate treatment and hydration. If your symptoms persist beyond 48 hours, worsen, or are accompanied by fever, blood in the stool, or severe abdominal pain, stop use immediately and consult a GP.

Chronic diarrhoea should only be managed with loperamide under the supervision of a doctor. Self-treating long-term bowel symptoms without a diagnosis is not advisable.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)

What Are the Most Common Side Effects of Galpharm Diarrhoea Relief 2mg?

Most people tolerate loperamide well at the recommended doses. However, as with any medicine, side effects can occur. The most common ones are related to the way loperamide slows down the gut, and they tend to be mild and short-lived.

  • Constipation — the most frequently reported side effect
  • Flatulence (wind) and bloating
  • Nausea
  • Abdominal cramps or discomfort
  • Headache

What Are the Less Common Side Effects of Galpharm Diarrhoea Relief 2mg?

Less commonly, some people experience side effects that are not directly related to gut motility. These are generally mild but worth being aware of, particularly if you are using this medicine for the first time.

  • Dizziness or drowsiness
  • Dry mouth
  • Skin rash, itching, or urticaria (hives)
  • Vomiting
  • Abdominal distension (swelling of the abdomen)
  • Fatigue

What Are the Serious Side Effects of Galpharm Diarrhoea Relief 2mg?

Serious side effects are rare when loperamide is used at the recommended dose for the recommended duration. However, you should stop taking this medicine and seek urgent medical attention if you experience any of the following:

  • Severe abdominal bloating or a rigid, distended abdomen — this could indicate paralytic ileus (a dangerous slowing of the bowel)
  • Signs of a serious allergic reaction: swelling of the face, lips, tongue, or throat; difficulty breathing; or a widespread skin rash
  • Irregular heartbeat or palpitations — particularly if you have taken more than the recommended dose

The MHRA has issued guidance noting that cardiac events have been reported with loperamide misuse at doses significantly above those recommended. This is why it is critical never to exceed the stated maximum daily dose.

What Should You Do If You Experience Side Effects of Galpharm Diarrhoea Relief 2mg?

If you experience mild side effects such as constipation or nausea, these will usually resolve once you stop taking the medicine. Drinking plenty of fluids and resting can help. If side effects are persistent, worsening, or causing you concern, stop use and speak to your pharmacist or GP as soon as possible.

You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. This helps regulators monitor the safety of medicines in real-world use.

Can Galpharm Diarrhoea Relief 2mg Interact With Other Medicines?

Yes — loperamide can interact with certain medicines, which may increase the amount of loperamide in your bloodstream and raise the risk of side effects. Always inform your pharmacist or doctor of all medicines you are currently taking, including prescription drugs, over-the-counter products, and herbal remedies.

  • Quinidine (used for heart rhythm problems) — may significantly increase loperamide blood levels
  • Ritonavir (used in HIV treatment) — may increase loperamide plasma concentrations
  • Itraconazole (antifungal) — may affect loperamide metabolism
  • Other medicines that reduce gut motility — combined use may cause excessive slowing of the bowel

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

We’re a safe and
regulated UK service

Registered Pharmacy Badge

Lowest Price Guarantee

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

100% discreet packaging

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

Agent

Need help?
Talk to our friendly experts now

How our service works

Service Setup

Service setup

Discreet Packaging

Discreet packaging

Express Delivery

Express delivery