Skip to product information
1 of 1

  • Images are for illustration purposes only

Fluconazole 150mg Capsule

Fluconazole 150mg Capsule

  • 1. Ozempic®️-equivalent therapy now available for weight management
  • 2. Average weight loss of 17%, with 1 in 3 patients achieving over 20%
  • 3. May help reduce osteoarthritis-related pain
  • 4. Wegovy®️ is not expected to impact the effectiveness of oral contraceptives
  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Treats vaginal thrush with a single 150mg oral capsule
  • ✔️ Targets Candida infection systemically from within the body
  • ✔️ Symptom relief often begins within 24 hours of taking
  • ✔️ Suitable for women aged 16 to 60 without a prescription
  • ✔️ No need for messy creams or multi-day pessary courses

Price Checker

Regular price £3.75
Sale price £3.75 £4.50
Sale Sold out
  • Lowest price guarantee
  • Includes FREE private prescription
View full details

 

What Is Fluconazole 150mg Capsule Used For?

 

Vaginal thrush is incredibly common — most women will experience it at least once in their lifetime. It is caused by an overgrowth of a yeast called Candida albicans, and it can cause itching, soreness, and a thick white discharge. The good news is that it is very treatable. The fluconazole 150mg capsule is a single-dose oral antifungal medicine that tackles the infection from the inside out, offering a convenient alternative to creams and pessaries. You can browse our full range of thrush treatments if you would like to compare your options before deciding.

Fluconazole belongs to a class of medicines called triazole antifungals. It is licensed in the UK for the treatment of vaginal candidiasis (thrush) in women aged 16 to 60 who have previously been diagnosed with the condition. It is available over the counter without a prescription, making it one of the most accessible thrush treatments available.

 

How Does Fluconazole 150mg Work Against Thrush?

 

Fluconazole targets the fungus directly by disrupting its ability to maintain a healthy cell membrane. Here is how it works step by step:

  • Fluconazole is absorbed into the bloodstream after you swallow the capsule.
  • It inhibits an enzyme called lanosterol 14-alpha-demethylase, which Candida fungi rely on to produce ergosterol.
  • Ergosterol is essential for the structural integrity of the fungal cell membrane.
  • Without it, the membrane becomes permeable and unstable, causing the fungal cells to die.
  • This stops the infection from spreading and allows your body to clear the remaining yeast naturally.

Because fluconazole works systemically — meaning it travels through your bloodstream — it can reach areas that topical treatments may not. That is why many people find a single oral capsule more convenient than a week-long course of cream.

 

Who Is Fluconazole 150mg Capsule Suitable For?

 

This medicine is suitable for a specific group of patients. It is not appropriate for everyone, so it is worth checking the criteria before purchasing. Fluconazole 150mg is generally suitable for:

  • Women aged 16 to 60 years old.
  • Those who have previously been diagnosed with vaginal thrush by a doctor.
  • People who recognise their current symptoms as consistent with a previous thrush episode.
  • Those who are not pregnant or breastfeeding.

It is not suitable for men, girls under 16, or women over 60 without medical supervision. If you are unsure whether this is the right treatment for you, speak to your pharmacist or GP before taking it.

 

How Does Fluconazole Compare to Clotrimazole for Thrush?

 

Feature Fluconazole 150mg Capsule Clotrimazole Pessary/Cream
Route of administration Oral (swallowed) Topical (applied locally)
Dosing Single capsule, one dose 1–7 days depending on strength
Suitable during pregnancy No Some formulations may be suitable — seek advice
Works systemically Yes No — local action only

 

How Should You Store Fluconazole 150mg Capsule?

 

Store your fluconazole 150mg capsule below 30°C in a dry place, away from direct sunlight and moisture. Keep it out of the reach and sight of children at all times. Do not use the capsule after the expiry date printed on the packaging. If you are looking for other treatments for related conditions, our women's health range includes a variety of options to support your wellbeing.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Fluconazole 150mg Capsule specifications
Treatment category Antifungal / Thrush treatment
Mechanism of action Inhibits fungal lanosterol 14-alpha-demethylase, disrupting ergosterol synthesis
Effective against Vaginal candidiasis (thrush) caused by Candida albicans
Suitable for Women aged 16–60 with previously diagnosed vaginal thrush
Active ingredient Fluconazole 150mg
Pack sizes 1 capsule
Strengths 150mg
UK classification Pharmacy (P) medicine
Drug class Triazole antifungal
Preparation Hard capsule
Route of administration Oral

Specifications of Fluconazole 150mg Capsule

 

What Is Fluconazole 150mg Capsule and What Is It Used For?

 

Fluconazole 150mg Capsule is an oral antifungal medicine used to treat vaginal thrush (vaginal candidiasis) in women. It contains the active ingredient fluconazole, a triazole antifungal that works systemically to eliminate the Candida yeast responsible for the infection. It is taken as a single capsule and is available over the counter from UK pharmacies for women aged 16 to 60 who have previously been diagnosed with thrush.

 

What Do You Need to Know Before Using Fluconazole 150mg Capsule?

 

Before taking this medicine, it is important to check that it is safe for you. Do not take fluconazole 150mg if any of the following apply:

  • You are allergic to fluconazole or any other azole antifungal medicine.
  • You are pregnant or think you might be pregnant.
  • You are breastfeeding.
  • You are under 16 or over 60 years of age.
  • You have liver or kidney problems.
  • You have a heart condition or a history of abnormal heart rhythm (QT prolongation).
  • Your symptoms are different from a previous thrush episode — this could indicate a different infection requiring medical assessment.

Fluconazole can interact with a number of medicines. Tell your pharmacist or doctor if you are taking any of the following:

  • Warfarin or other anticoagulants (blood thinners).
  • Terfenadine or astemizole (antihistamines).
  • Cisapride (used for digestive problems).
  • Rifampicin (an antibiotic).
  • Certain medicines for epilepsy such as phenytoin.
  • Some oral hypoglycaemic medicines used for diabetes.

 

How Should You Take Fluconazole 150mg Capsule?

 

Always take this medicine exactly as described in the patient information leaflet or as directed by your pharmacist. The steps below outline the standard approach for adults:

  1. Take one 150mg capsule by mouth.
  2. Swallow it whole with a full glass of water.
  3. It can be taken with or without food — it makes no difference to how well it works.
  4. Only one capsule is required for a single course of treatment.
  5. Do not take a second capsule unless advised to do so by a doctor.
Indication Age Group Dose Frequency
Vaginal thrush (OTC use) Women aged 16–60 150mg (1 capsule) Single dose
Recurrent thrush (under medical supervision) Adults 150mg As directed by a doctor

If your symptoms do not improve within 7 days of taking the capsule, or if they return within two months, you should see your GP. Recurring thrush may need further investigation. You might also find it helpful to explore our athletes foot and fungal infections range if you are dealing with other fungal conditions alongside thrush.

 

What Are the Possible Side Effects of Fluconazole 150mg Capsule?

 

Like all medicines, fluconazole can cause side effects, although not everyone experiences them. Most side effects are mild and resolve on their own.

Common side effects (may affect up to 1 in 10 people):

  • Nausea or feeling sick
  • Headache
  • Abdominal pain or stomach discomfort
  • Diarrhoea
  • Flatulence (wind)

Less common side effects (may affect up to 1 in 100 people):

  • Dizziness
  • Skin rash or itching
  • Indigestion
  • Taste disturbance
  • Muscle pain

Rarely, fluconazole can cause serious liver reactions or severe skin conditions such as Stevens-Johnson syndrome. Stop taking the medicine and seek immediate medical attention if you develop yellowing of the skin or eyes, severe skin blistering, or difficulty breathing.

 

How Should You Store Fluconazole 150mg Capsule?

 

  • Store below 30°C in a cool, dry place.
  • Keep away from direct sunlight and moisture.
  • Keep out of the reach and sight of children.
  • Do not use after the expiry date printed on the pack.
  • Do not dispose of medicines via wastewater or household waste — return unused medicines to your pharmacy.

If you are managing other aspects of your health alongside thrush treatment, our condoms and sexual health range may also be of interest, particularly if you are looking to reduce the risk of reinfection.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy fluconazole 150mg capsule online in the UK?

You can buy Fluconazole 150mg Capsule online from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £3.75. It is available without a prescription for women aged 16 to 60 who have previously been diagnosed with vaginal thrush. Simply add it to your basket and complete a short health questionnaire to ensure it is suitable for you.

How does fluconazole 150mg work in the body?

Fluconazole works by blocking an enzyme called lanosterol 14-alpha-demethylase, which the Candida fungus needs to produce ergosterol — a vital component of its cell membrane. Without ergosterol, the fungal cell membrane breaks down and the organism cannot survive. This mechanism means fluconazole works systemically, reaching the site of infection through your bloodstream rather than just on the surface.

How do I take fluconazole 150mg capsule step by step?

Taking fluconazole 150mg is straightforward — swallow one capsule whole with a full glass of water. You can take it with or without food, and no special timing is required. Only one capsule is needed for a single course of treatment; do not take a second dose unless a doctor has specifically advised you to.

How long does fluconazole 150mg take to work?

Many people notice an improvement in their thrush symptoms within 24 hours of taking fluconazole 150mg. However, it can take up to 7 days for symptoms to fully resolve in some cases. If your symptoms have not improved after 7 days, or if they return within two months, you should see your GP for further assessment.

What is the best time of day to take fluconazole 150mg?

There is no specific best time of day to take fluconazole 150mg — it can be taken at any time, with or without food. Because it is a single-dose treatment, timing is less critical than with medicines taken over multiple days. Choose a time that is convenient for you and easy to remember.

What are the side effects of fluconazole 150mg and how do I manage them?

The most common side effects of fluconazole 150mg include nausea, headache, abdominal pain, diarrhoea, and flatulence. These are usually mild and short-lived. Taking the capsule with food may help reduce stomach discomfort, and staying well hydrated can ease headaches. If you experience a severe skin reaction, yellowing of the skin, or difficulty breathing, stop taking the medicine and seek urgent medical attention.

Who should not take fluconazole 150mg capsule?

Fluconazole 150mg is not suitable for women who are pregnant, breastfeeding, under 16, or over 60 years of age. It should also be avoided by anyone with liver or kidney problems, a history of heart rhythm abnormalities, or those taking interacting medicines such as warfarin, terfenadine, or cisapride. Always check with your pharmacist if you are unsure whether this medicine is right for you.

What happens if I miss a dose of fluconazole?

Because fluconazole 150mg is a single-dose treatment for thrush, missing a dose is not typically applicable in the same way as with multi-day medicines. If you have been prescribed a longer course by your doctor and forget a dose, take it as soon as you remember — unless it is nearly time for your next dose, in which case skip the missed one. Never double up doses.

Can I drink alcohol while taking fluconazole 150mg?

There is no direct interaction between fluconazole and alcohol, but drinking alcohol while you have an active thrush infection is generally not recommended as it can affect your immune response and overall recovery. It is always sensible to drink in moderation when taking any medicine. If you have concerns, speak to your pharmacist for personalised advice.

Is fluconazole 150mg safe to use if I am on the contraceptive pill?

Fluconazole does not reduce the effectiveness of the combined oral contraceptive pill or the progestogen-only pill. However, if you experience vomiting or diarrhoea as a side effect of fluconazole, this could potentially affect how well your pill is absorbed — follow the guidance in your contraceptive pill leaflet in that situation. If in doubt, speak to your pharmacist or GP.

What are the alternatives to fluconazole for treating thrush?

The main alternative to fluconazole for vaginal thrush is clotrimazole, which is available as a pessary, internal cream, or external cream. Clotrimazole works topically rather than systemically and may be more suitable for women who are pregnant or cannot take oral medicines. You can explore our full thrush treatment range to compare your options.

Can fluconazole 150mg be used to treat oral thrush?

Fluconazole is used medically to treat oral thrush, but the over-the-counter 150mg capsule is specifically licensed for vaginal thrush in women aged 16 to 60. Oral thrush typically requires a prescription and a different dosing regimen. If you think you have oral thrush, please see your GP or dentist for an appropriate diagnosis and treatment plan.

How long can you keep taking fluconazole for recurrent thrush?

For recurrent vaginal thrush (defined as four or more episodes per year), a doctor may prescribe a longer maintenance course of fluconazole — typically one 150mg capsule weekly for six months. This type of extended use should only be undertaken under medical supervision. Over-the-counter use is intended for single episodes only, not ongoing self-treatment.

Can men use fluconazole 150mg capsule for thrush?

The over-the-counter fluconazole 150mg capsule is not licensed for use in men. Men who think they have penile thrush should speak to their GP or visit a sexual health clinic for an appropriate diagnosis and treatment. You can find relevant products in our men's health range, though a medical consultation is recommended first.

What does the latest research say about fluconazole for thrush?

Fluconazole has been used clinically for decades and remains one of the most well-studied antifungal medicines available. Current NHS guidance continues to recommend it as a first-line oral treatment for uncomplicated vaginal candidiasis. Ongoing research is focused on managing fluconazole-resistant strains of Candida, which remain relatively uncommon in otherwise healthy individuals but are an emerging concern in immunocompromised patients.

How Should You Use Fluconazole 150mg Capsule?

Using fluconazole 150mg correctly is straightforward, but it is still worth following the steps below to make sure you get the most from your treatment. Always read the patient information leaflet supplied with your medicine before taking it.

If you are also using a topical cream to relieve external itching and soreness, this can be used alongside the capsule. The capsule treats the internal infection while the cream addresses surface symptoms.

What Is the Correct Dose of Fluconazole 150mg Capsule?

The standard over-the-counter dose for vaginal thrush is a single 150mg capsule taken once. This is sufficient for most uncomplicated episodes of thrush in otherwise healthy women. Do not take more than one capsule without medical advice.

When Is the Best Time to Use Fluconazole 150mg Capsule?

There is no specific time of day that is clinically superior for taking fluconazole 150mg. Because it is a single-dose treatment, you simply take it at a time that is convenient for you — morning, afternoon, or evening all work equally well. Some people prefer to take it in the evening so that any mild stomach discomfort passes overnight.

If you are also using an external antifungal cream for symptom relief, you can apply this at any time of day as needed, independently of when you took the capsule.

How Long Can You Use Fluconazole 150mg Capsule For?

For over-the-counter use, fluconazole 150mg is intended as a single-dose, one-off treatment per episode of vaginal thrush. You should not take repeated doses without consulting a doctor. If your symptoms return within two months, or if you experience more than two episodes of thrush in six months, you should see your GP rather than self-treating again.

Recurrent thrush may require a longer course of treatment under medical supervision, or investigation into an underlying cause such as diabetes or a weakened immune system. Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Fluconazole 150mg Capsule?

Most people tolerate fluconazole 150mg well, but like all medicines, it can cause side effects in some people. Common side effects affect up to 1 in 10 people and are generally mild and short-lived.

  • Nausea or feeling sick
  • Headache
  • Abdominal pain or stomach cramps
  • Diarrhoea
  • Flatulence (wind)

Taking the capsule with food may help reduce stomach-related side effects. Drinking plenty of water and resting can also help ease headaches.

What Are the Less Common Side Effects of Fluconazole 150mg Capsule?

Less common side effects affect up to 1 in 100 people. These are not usually serious but are worth being aware of.

  • Dizziness or feeling lightheaded
  • Skin rash or itching
  • Indigestion or heartburn
  • Taste disturbance (things tasting different than usual)
  • Muscle pain or weakness
  • Dry mouth

If any of these side effects bother you or do not go away, speak to your pharmacist for advice.

What Are the Serious Side Effects of Fluconazole 150mg Capsule?

Serious side effects are rare but can occur. You should stop taking fluconazole and seek immediate medical attention if you experience any of the following:

  • Yellowing of the skin or whites of the eyes (jaundice) — a possible sign of liver problems.
  • Severe skin reactions such as blistering, peeling, or a widespread rash — these could indicate Stevens-Johnson syndrome or toxic epidermal necrolysis.
  • Irregular or fast heartbeat (palpitations).
  • Difficulty breathing or swelling of the face, lips, or throat — signs of a serious allergic reaction (anaphylaxis).
  • Unusual bruising or bleeding.

These reactions are uncommon, but they require urgent medical assessment. Do not ignore them or wait to see if they improve on their own.

What Should You Do If You Experience Side Effects of Fluconazole?

For mild side effects such as nausea or headache, supportive measures like staying hydrated, eating a light meal, and resting are usually sufficient. If a side effect is persistent, worsening, or causing significant distress, contact your pharmacist or GP. You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk — this helps improve medicine safety for everyone.

Can Fluconazole 150mg Interact With Other Medicines?

Yes — fluconazole has a number of clinically significant drug interactions. It can increase the blood-thinning effect of warfarin, raising the risk of bleeding. It should not be taken alongside terfenadine, astemizole, or cisapride due to the risk of serious heart rhythm abnormalities. Rifampicin can reduce the effectiveness of fluconazole, and fluconazole may increase the levels of certain epilepsy medicines such as phenytoin in your blood. Always tell your pharmacist about all medicines, supplements, and herbal remedies you are taking before using fluconazole. If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

We’re a safe and
regulated UK service

Registered Pharmacy Badge

Lowest Price Guarantee

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

100% discreet packaging

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

Agent

Need help?
Talk to our friendly experts now

How our service works

Service Setup

Service setup

Discreet Packaging

Discreet packaging

Express Delivery

Express delivery