Skip to product information
1 of 1

  • Images are for illustration purposes only

Fixodent Plus Food Seal Denture Adhesive Cream 40g for Full & Partial Dentures.

Fixodent Plus Food Seal Denture Adhesive Cream 40g for Full & Partial Dentures.

  • 1. Ozempic®️-equivalent therapy now available for weight management
  • 2. Average weight loss of 17%, with 1 in 3 patients achieving over 20%
  • 3. May help reduce osteoarthritis-related pain
  • 4. Wegovy®️ is not expected to impact the effectiveness of oral contraceptives
  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Holds full and partial dentures securely all day
  • ✔️ Creates a food seal to prevent particles getting underneath
  • ✔️ Suitable for both full and partial removable dentures
  • ✔️ Single morning application lasts throughout the day
  • ✔️ Reduces denture movement for greater eating confidence

Price Checker

Regular price £3.60
Sale price £3.60
Sale Sold out
  • Lowest price guarantee
  • Includes FREE private prescription
View full details

 

What Is Fixodent Plus Food Seal Denture Adhesive Cream?

 

If you wear dentures, you'll know how much confidence comes from knowing they'll stay put throughout the day. Fixodent Plus Food Seal denture adhesive cream is a well-established over-the-counter product designed to help hold both full and partial dentures securely in place, while also creating a seal that helps keep food particles from slipping underneath. Available in a convenient 40g tube, it's a practical everyday solution for denture wearers who want to eat, speak, and smile without worry. You can find it alongside other oral health products at Cured Pharmacy.

Denture adhesives are widely used across the UK. The NHS acknowledges that adhesives can help improve the fit and comfort of dentures, particularly when dentures have become slightly loose over time due to natural changes in the shape of the gums and jawbone. That said, if you find yourself relying heavily on adhesive, it's worth speaking to your dentist — it may be time for a denture reline or replacement.

 

How Does Fixodent Plus Food Seal Denture Adhesive Cream Work?

 

The mechanism is straightforward but effective. When the cream comes into contact with saliva, it swells and forms a firm, cushioning layer between the denture base and your gum tissue. This layer fills small gaps, reduces movement, and creates a physical barrier — the "food seal" — that helps stop food particles from working their way underneath the denture during meals.

  • The active ingredient, calcium-sodium PVM/MA copolymer, absorbs moisture from saliva and expands to fill the space between denture and gum.
  • This creates a firm but comfortable cushion that reduces denture movement.
  • The seal formed around the denture edges helps prevent food from getting trapped underneath.
  • The hold typically lasts throughout the day with a single application.

 

Who Should Use Fixodent Plus Food Seal Denture Adhesive Cream?

 

This product is suitable for adults who wear removable full or partial dentures and want additional security and comfort during daily activities. It's particularly useful if your dentures feel slightly loose, if you eat a varied diet, or if you simply want extra peace of mind throughout the day.

  • Adults with full upper or lower dentures seeking a more secure fit.
  • Adults with partial dentures who want to reduce movement during eating or speaking.
  • People whose dentures have become slightly loose due to natural gum changes.
  • Those who want to reduce food trapping under their dentures at mealtimes.

 

How Does Fixodent Plus Food Seal Compare to Other Denture Adhesives?

 

Feature Fixodent Plus Food Seal Standard Denture Adhesive Cream
Food seal barrier Yes — specifically formulated Not always included
Suitable for full dentures Yes Yes
Suitable for partial dentures Yes Varies by product
Pack size 40g Varies

 

How Should You Store Fixodent Plus Food Seal and Is It Clinically Suitable for You?

 

Store the tube below 25°C, away from direct sunlight and out of reach of children. Once opened, replace the cap firmly after each use to prevent the cream from drying out. The product does not require refrigeration. You can browse our full range of dental products if you're looking for complementary oral care items.

This denture adhesive cream is not suitable for use on broken or damaged dentures, and it should not be used as a substitute for a proper dental assessment. If you have known allergies to any of the listed ingredients, do not use this product. Using a denture adhesive cream regularly when dentures fit poorly is not a long-term solution — your dentist should be consulted if the fit has changed significantly.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Fixodent Plus Food Seal Denture Adhesive Cream 40g specifications
Treatment category Oral care / Denture care
Mechanism of action Forms a cushioning adhesive layer between denture and gum tissue on contact with saliva
Effective for Securing full and partial dentures; reducing food trapping under dentures
Suitable for Adults wearing full or partial removable dentures
Active ingredient Calcium-sodium PVM/MA copolymer
Pack size 40g
UK classification General Sale (GSL)
Preparation Cream
Route of administration Topical (oral — applied to denture surface)

Specifications of Fixodent Plus Food Seal Denture Adhesive Cream 40g

 

What Is Fixodent Plus Food Seal and What Is It Used For?

 

Fixodent Plus Food Seal Denture Adhesive Cream is an over-the-counter oral care product used to improve the fit, comfort, and stability of removable full and partial dentures. It is applied directly to the fitting surface of the denture before insertion. The cream helps hold the denture in place throughout the day and creates a seal along the denture edges to help prevent food particles from becoming trapped underneath — a common source of discomfort and irritation for denture wearers.

The NHS notes that dentures can become loose over time as the shape of the gums and underlying bone changes naturally. A denture adhesive cream can provide a temporary improvement in comfort and security, though it is not a substitute for a properly fitting denture assessed by a dentist.

 

What Do You Need to Know Before Using Fixodent Plus Food Seal?

 

Before using this product, read the following carefully. Do not use Fixodent Plus Food Seal if any of the contraindications below apply to you.

Do not use if:

  • You are allergic to calcium-sodium PVM/MA copolymer or any other listed ingredient.
  • Your dentures are cracked, broken, or damaged — adhesive is not a repair solution.
  • You are under 18 years of age.
  • You have open sores, ulcers, or wounds in your mouth — seek dental advice first.

Warnings:

  • If you need to use large amounts of adhesive to achieve a hold, your dentures may no longer fit correctly — consult your dentist.
  • Do not swallow the cream. If accidental ingestion occurs in large amounts, seek medical advice.
  • Keep out of reach of children.
  • For external use on dentures only — do not apply directly to gum tissue.

Drug interactions:

  • No clinically significant drug interactions are known for this topically applied denture adhesive cream.
  • If you are taking any medicines and are unsure, speak to your pharmacist before use.

 

How Should You Use Fixodent Plus Food Seal?

 

Follow these steps carefully each time you use the product. Using the correct technique ensures the best hold and helps you avoid using more cream than necessary.

  1. Clean your dentures thoroughly and dry them as much as possible before applying.
  2. Apply three to four small dots or short strips of cream to the fitting surface of the denture. Do not apply too close to the denture edges.
  3. Press the denture firmly into position in your mouth and hold for a few seconds to allow the adhesive to set.
  4. Avoid eating or drinking for at least 15 minutes after insertion to allow the adhesive to fully activate.
  5. To remove the denture at the end of the day, rinse your mouth with warm water and gently ease the denture out. Clean any remaining adhesive from both the denture and your gums.
Indication Age Group Dose Frequency
Full denture adhesion Adults (18+) 3–4 small dots or strips per denture Once daily (morning)
Partial denture adhesion Adults (18+) 2–3 small dots or strips per denture Once daily (morning)

 

What Are the Possible Side Effects of Fixodent Plus Food Seal?

 

Side effects with this product are uncommon when used as directed. However, as with any oral care product, some people may experience reactions. If you notice anything unusual, stop use and speak to your pharmacist or dentist. You might also find it helpful to explore our wider range of oral health products if you're managing ongoing mouth discomfort.

Common side effects:

  • Mild gum irritation at the site of contact.
  • Slight change in taste sensation.
  • Temporary mouth soreness if the denture is pressing unevenly.

Less common side effects:

  • Allergic reaction — redness, swelling, or itching inside the mouth (stop use immediately and seek advice).
  • Nausea if a significant amount is accidentally swallowed.

If you experience any signs of a serious allergic reaction — such as swelling of the lips, tongue, or throat, or difficulty breathing — seek emergency medical attention immediately.

 

How Should You Store Fixodent Plus Food Seal?

 

Correct storage keeps the product effective for its full shelf life. If you're also managing other health products at home, our dental products collection includes a range of items that can be stored similarly.

  • Store below 25°C in a cool, dry place.
  • Keep away from direct sunlight and sources of heat.
  • Replace the cap firmly after every use to prevent the cream from drying out.
  • Do not refrigerate.
  • Keep out of reach and sight of children.
  • Do not use after the expiry date printed on the tube or carton.
  • Do not dispose of via wastewater or household waste — return unused product to your pharmacy.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Fixodent Plus Food Seal denture adhesive cream online in the UK?

You can buy Fixodent Plus Food Seal Denture Adhesive Cream 40g directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. No prescription is needed — it is a General Sale (GSL) product available to adults. Simply add it to your basket and choose your preferred delivery option for fast, discreet dispatch.

How does Fixodent Plus Food Seal denture adhesive cream work in the mouth?

When the cream comes into contact with saliva, the active ingredient — calcium-sodium PVM/MA copolymer — absorbs moisture and swells to form a firm, cushioning layer between the denture base and your gum tissue. This layer fills small gaps, reduces denture movement, and creates a seal along the denture edges to help prevent food from getting underneath. The result is a more stable, comfortable fit throughout the day.

How do I apply Fixodent Plus Food Seal step by step?

Start by cleaning and drying your dentures thoroughly. Apply three to four small dots or short strips of cream to the fitting surface of the denture, keeping the cream away from the edges. Press the denture firmly into place and hold for a few seconds, then avoid eating or drinking for at least 15 minutes to allow the adhesive to fully activate.

How much denture adhesive cream should I use each time?

Use the smallest amount that gives you a secure, comfortable hold — usually three to four small dots or short strips per denture. Using more than needed does not improve the hold and may make the denture harder to remove. If you consistently need large amounts to achieve a hold, your dentures may no longer fit correctly and you should visit your dentist.

Can Fixodent Plus Food Seal be used with partial dentures?

Yes — Fixodent Plus Food Seal is specifically designed for use with both full and partial removable dentures. For partial dentures, you may need slightly less cream than for a full denture, as the fitting area is smaller. Apply two to three small dots or strips to the fitting surface and press firmly into place as usual.

What is the best time of day to apply Fixodent denture adhesive cream?

The best time to apply Fixodent Plus Food Seal is in the morning, after cleaning and drying your dentures, before you insert them for the day. A single morning application is designed to last throughout the day. Applying at the start of the day means the adhesive is active during mealtimes when a secure hold matters most.

How long does Fixodent Plus Food Seal hold dentures in place?

Fixodent Plus Food Seal is formulated to provide all-day hold from a single morning application. How long the hold lasts in practice can vary depending on your diet, saliva production, and how well your dentures currently fit. If the hold is not lasting through the day, speak to your dentist about whether your dentures need relining or replacing.

Are there any side effects of using Fixodent Plus Food Seal denture adhesive cream?

Side effects are uncommon when the product is used as directed. Some people may experience mild gum irritation, a slight change in taste, or temporary mouth soreness. Rarely, an allergic reaction may occur — if you notice swelling, redness, or itching inside your mouth, stop use immediately and seek advice from your pharmacist or dentist.

Who is eligible to use Fixodent Plus Food Seal denture adhesive cream?

This product is suitable for adults aged 18 and over who wear removable full or partial dentures. It is not suitable for children, for people with known allergies to any of the ingredients, or for use on cracked or broken dentures. If you have open sores or ulcers in your mouth, consult your dentist before use. You can explore our full oral health range for complementary products.

What happens if I accidentally swallow some Fixodent denture adhesive cream?

Swallowing a small amount of denture adhesive cream during normal use is unlikely to cause harm. However, if a large amount is accidentally swallowed — particularly by a child — seek medical advice promptly. Contact NHS 111 or your nearest A&E if you are concerned. Always store the product out of reach of children.

Can I use Fixodent Plus Food Seal if my dentures are broken or cracked?

No — you should not use denture adhesive cream on damaged dentures. A cracked or broken denture needs to be repaired or replaced by a dental professional before adhesive is used. Using adhesive on a damaged denture can cause further damage to the denture and may irritate or injure your gum tissue.

How do I remove Fixodent denture adhesive cream from my gums and dentures?

To remove your dentures at the end of the day, rinse your mouth with warm water first to help loosen the adhesive, then gently ease the denture out. Clean any remaining adhesive from the denture surface using a soft brush and warm water. Rinse your gums gently with warm water to remove any residue from the gum tissue.

What are the alternatives to Fixodent Plus Food Seal denture adhesive?

Alternatives include other denture adhesive creams such as Poligrip, as well as denture adhesive strips and powders. Each format has different application methods and hold characteristics. The right choice depends on your denture type and personal preference — your dentist or pharmacist can help you decide. Browse our dental products collection to see what's available.

How long can I keep using Fixodent Plus Food Seal denture adhesive cream?

You can use Fixodent Plus Food Seal as part of your daily denture care routine for as long as your dentures require adhesive support. However, if you find your reliance on adhesive is increasing over time, this is a sign that your dentures may no longer fit correctly. The NHS recommends having your dentures checked by a dentist regularly — typically every year or two — to ensure they still fit well.

Is there any research supporting the use of denture adhesive creams?

Yes — clinical studies have shown that denture adhesives can improve denture retention, stability, and chewing efficiency in denture wearers, particularly those with looser-fitting dentures. The NHS acknowledges that adhesives can help improve comfort and confidence for denture wearers. They are not, however, a long-term substitute for a well-fitting denture assessed and maintained by a dental professional.

How Should You Use Fixodent Plus Food Seal Denture Adhesive Cream?

Using Fixodent Plus Food Seal correctly makes a real difference to how well it works. Always start with clean, dry dentures — any moisture or residue on the fitting surface can reduce the adhesive's effectiveness and shorten how long the hold lasts.

Follow these steps each morning for the best results:

What Is the Correct Dose of Fixodent Plus Food Seal Denture Adhesive Cream?

There is no single fixed dose — the right amount is the smallest quantity that gives you a comfortable, secure hold. Using more cream than needed does not improve the hold and can make the denture harder to remove at the end of the day.

Use the table below as a general guide:

When Is the Best Time to Use Fixodent Plus Food Seal Denture Adhesive Cream?

Apply the cream in the morning, immediately before inserting your dentures for the day. This ensures the adhesive is fully active during mealtimes and social activities when a secure hold matters most. Avoid applying the cream late in the day or just before removing your dentures, as this wastes product and provides no benefit.

If you find the hold is wearing off before the end of the day, consider whether your dentures may need a professional assessment rather than applying a second dose of adhesive.

How Long Can You Use Fixodent Plus Food Seal Denture Adhesive Cream For?

You can use this product as part of your daily denture care routine for as long as your dentures require adhesive support. However, if you notice that you are needing increasing amounts of cream to achieve a hold, or if the hold is consistently poor, this suggests your dentures may no longer fit correctly. The NHS recommends having your dentures checked by a dentist regularly — at least every one to two years — to ensure they still fit well and are not causing damage to your gum tissue or jawbone.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)

What Are the Most Common Side Effects of Fixodent Plus Food Seal Denture Adhesive Cream?

Most people use Fixodent Plus Food Seal without experiencing any side effects, particularly when the product is used as directed. However, as with any product applied inside the mouth, some people may notice mild reactions, especially when first starting to use it.

  • Mild gum irritation or tenderness at the contact site.
  • Slight change in taste sensation while the adhesive is active.
  • Temporary mouth soreness if the denture is pressing unevenly on the gum tissue.

These effects are usually mild and short-lived. If they persist beyond a few days, stop using the product and speak to your dentist or pharmacist.

What Are the Less Common Side Effects of Fixodent Plus Food Seal Denture Adhesive Cream?

Less commonly, some people may experience reactions that require attention. These are not typical but are worth being aware of before you start using the product.

  • Redness or swelling of the gum tissue at the site of contact.
  • Nausea, if a significant amount of cream is accidentally swallowed during use.
  • Increased saliva production in the first few days of use.
  • Difficulty removing the denture if too much cream has been applied.

What Are the Serious Side Effects of Fixodent Plus Food Seal Denture Adhesive Cream?

Serious side effects are rare but can occur if you have an undiagnosed allergy to any of the ingredients. Signs of a serious allergic reaction include swelling of the lips, tongue, or throat, difficulty breathing, a widespread skin rash, or dizziness. If you experience any of these symptoms after using this product, stop use immediately and seek emergency medical attention by calling 999 or going to your nearest A&E department.

What Should You Do If You Experience Side Effects of Fixodent Plus Food Seal?

For mild side effects such as gum irritation or taste changes, try reducing the amount of cream you apply and ensure you are keeping the cream away from the denture edges. If symptoms persist after adjusting your technique, stop use and consult your dentist or pharmacist. They can help determine whether the reaction is related to the adhesive or to the fit of your dentures.

For any suspected allergic reaction — however mild — stop use immediately and seek professional advice before using the product again. Do not attempt to manage a suspected allergic reaction at home without guidance.

Can Fixodent Plus Food Seal Denture Adhesive Cream Interact With Other Medicines?

No clinically significant drug interactions have been identified for this topically applied denture adhesive cream. Because the product is applied to the surface of the denture and is not intended to be absorbed into the body, the risk of systemic interactions is very low. However, if you are taking any prescribed medicines and are unsure whether this product is suitable for you, speak to your pharmacist before use — they can advise based on your full medication history.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

We’re a safe and
regulated UK service

Registered Pharmacy Badge

Lowest Price Guarantee

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

100% discreet packaging

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

Agent

Need help?
Talk to our friendly experts now

How our service works

Service Setup

Service setup

Discreet Packaging

Discreet packaging

Express Delivery

Express delivery