Fixodent Plus Dual Power Best Hold 40g
- ✔️ Zinc-free formula safe for daily long-term denture use
- ✔️ Creates a firm seal lasting up to 12 hours
- ✔️ Dual action blocks food particles under dentures
- ✔️ Suitable for full and partial removable dentures
- ✔️ Activates on contact with saliva for instant hold
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What Is Fixodent Plus Dual Power Denture Adhesive Cream?
Living with dentures can take some getting used to. Whether you've had them for years or you're newly adjusting, one of the most common concerns is keeping them securely in place throughout the day. That's exactly where denture adhesive cream comes in. Fixodent Plus Dual Power Best Hold 40g is a zinc-free adhesive cream designed to create a firm, comfortable seal between your denture and your gum tissue — giving you the confidence to eat, speak, and smile without worrying about slippage. You can find it alongside other dental products at Cured Pharmacy.
Fixodent has been a trusted name in denture care for decades. The Dual Power formula is specifically designed to tackle two key challenges at once: holding strength and food particle resistance. It's available over the counter without a prescription, making it easy to order and use at home.
How Does Fixodent Plus Dual Power Work?
The mechanism behind this product is straightforward but effective. When you apply the cream to your denture and press it against your gum, the adhesive polymers absorb moisture from saliva and swell slightly. This swelling action fills the microscopic gaps between the denture base and your gum tissue, creating a cushioned, secure seal.
- The polymer blend (PVM/MA copolymer and sodium carboxymethylcellulose) activates on contact with moisture
- The adhesive expands to conform to the unique contours of your gum tissue
- A physical barrier forms that helps prevent food particles from getting underneath the denture
- The seal remains stable for up to 12 hours under normal conditions
Importantly, the formula is zinc-free. This matters because earlier generations of denture adhesives contained zinc, and concerns were raised about neurological effects associated with excessive long-term zinc ingestion from these products. Fixodent Plus Dual Power avoids this entirely.
Who Should Use Fixodent Plus Dual Power?
This product is suitable for most adults who wear removable dentures — full or partial — and want a more secure, comfortable fit during daily activities. It's particularly useful if your dentures feel slightly loose, if you're eating foods that tend to dislodge them, or if you simply want extra reassurance throughout the day.
- Adults with full upper or lower dentures
- Adults with partial dentures seeking additional stability
- People who find their dentures shift during eating or speaking
- Those who have recently had new dentures fitted and are still adjusting
It is not intended as a substitute for a properly fitted denture. If your dentures feel persistently loose or uncomfortable, you should see your dentist rather than relying solely on adhesive cream. Good oral health is important for denture wearers — if you're also managing other aspects of your oral care, our oral health collection has a range of relevant products.
How Does Fixodent Plus Dual Power Compare to Other Denture Adhesives?
| Feature | Fixodent Plus Dual Power 40g | Standard Denture Adhesive Cream |
|---|---|---|
| Zinc-free formula | Yes | Varies by brand |
| Food particle barrier | Yes — dual action | Limited |
| Hold duration | Up to 12 hours | Typically 4–8 hours |
| Suitable for partial dentures | Yes | Varies |
Is Fixodent Plus Dual Power Suitable for Sensitive Gums?
If you have sensitive gum tissue, the zinc-free formulation of this denture adhesive cream is generally well tolerated. The absence of zinc reduces the risk of irritation associated with older adhesive formulations. That said, if you have known allergies to any of the listed ingredients, you should check the full ingredient list before use and speak to your pharmacist if you're unsure.
Store the product below 25°C and keep the cap tightly closed after each use to maintain the integrity of the adhesive. Do not use on cracked or damaged dentures, as this may affect both the seal and your oral tissue.
This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.
Fixodent Plus Dual Power Best Hold 40g specifications
| Treatment category | Denture care / oral care |
| Mechanism of action | Polymer adhesive swells on contact with moisture to form a cushioned seal between denture and gum |
| Effective | Up to 12 hours per application |
| Suitable for | Adults with full or partial removable dentures |
| Active ingredient | PVM/MA copolymer, sodium carboxymethylcellulose (zinc-free) |
| Pack size | 40g |
| UK classification | General Sale (GSL) |
| Preparation | Cream |
| Route of administration | Topical (oral — applied to denture surface) |
Specifications of Fixodent Plus Dual Power Best Hold 40g
What Is Fixodent Plus Dual Power and What Is It Used For?
Fixodent Plus Dual Power Best Hold 40g is an over-the-counter denture adhesive cream used to improve the fit and stability of removable dentures. It is applied directly to the fitting surface of the denture before insertion into the mouth. The product is intended for adults who wear full or partial dentures and want a more secure hold during everyday activities such as eating, speaking, and socialising.
The NHS advises that denture adhesives can be helpful when dentures feel slightly loose, but they should not be used as a long-term substitute for a properly fitted denture. If your dentures are causing persistent discomfort or feel significantly loose, you should consult your dentist for a review or reline.
What Do You Need to Know Before Using Fixodent Plus Dual Power?
Before using this product, read the following carefully. While Fixodent Plus Dual Power is generally safe for most adults, there are some important considerations.
Do not use this product if:
- You are allergic to any of the listed ingredients, including PVM/MA copolymer or sodium carboxymethylcellulose
- Your dentures are cracked, broken, or significantly ill-fitting — see your dentist first
- You have open sores, ulcers, or wounds in your mouth — allow these to heal before use
- You are under 18 years of age — this product is intended for adults only
Warnings and precautions:
- Use only the recommended amount — excessive use does not improve hold and may cause product to ooze into the mouth
- Do not swallow the adhesive cream
- Keep out of reach of children
- If irritation or allergic reaction occurs, discontinue use and seek advice from your pharmacist or GP
Known drug interactions:
- No clinically significant drug interactions are currently known for this product
- As the product is applied topically to the denture and not ingested, systemic interactions are not expected
How Should You Use Fixodent Plus Dual Power?
Using the correct technique makes a real difference to how well the adhesive performs. Follow these steps each time you apply the cream.
- Clean your dentures thoroughly and allow them to dry slightly — the adhesive bonds better to a clean surface
- Apply small dots or short strips of cream to the fitting surface of the denture — do not spread it
- For upper dentures, apply three small strips: one along the centre ridge and one on each side
- For lower dentures, apply two short strips along the inner ridge
- Press the denture firmly into place and hold for a few seconds
- Avoid eating or drinking for at least 15 minutes after insertion to allow the adhesive to set
- To remove, gently prise the denture away from the gum using a rocking motion, then clean off any residue
| Indication | Age Group | Dose | Frequency |
|---|---|---|---|
| Full upper denture | Adults | 3 small strips or dots | Once daily |
| Full lower denture | Adults | 2 short strips | Once daily |
| Partial denture | Adults | Small dots at fitting points | Once daily |
If you find you need to reapply during the day, this may indicate that your dentures need professional attention. Speak to your dentist. You might also find it helpful to browse our oral health range for complementary denture care products.
What Are the Possible Side Effects of Fixodent Plus Dual Power?
Side effects from denture adhesive creams are uncommon when used as directed. However, as with any product applied in the mouth, some people may notice mild reactions.
Common side effects:
- Mild gum irritation or redness at the site of contact
- Temporary altered or unusual taste in the mouth
- Slight discomfort if too much product is applied
Less common side effects:
- Allergic reaction — including swelling, itching, or rash inside the mouth (stop use immediately if this occurs)
- Nausea if a significant amount of adhesive is accidentally swallowed
If you experience any persistent or concerning symptoms, stop using the product and contact your pharmacist or GP. For general pain or discomfort in the mouth area, our pain relief collection may offer additional support while you seek advice.
How Should You Store Fixodent Plus Dual Power?
- Store below 25°C in a cool, dry place
- Keep the cap tightly closed after every use to prevent the cream from drying out
- Do not store in direct sunlight or near a heat source
- Keep out of reach and sight of children
- Do not use after the expiry date printed on the tube
- Do not freeze
References
Written and reviewed by our qualified team
Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.
Frequently Asked Questions
Where can I buy Fixodent Plus Dual Power Best Hold 40g online in the UK?
You can buy Fixodent Plus Dual Power Best Hold 40g directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available without a prescription and can be delivered to your home. Browse our full range of dental products for more denture care options.
How does Fixodent Plus Dual Power denture adhesive cream work?
Fixodent Plus Dual Power works by using a moisture-activated polymer blend that swells on contact with saliva. This creates a cushioned, firm seal between the denture base and your gum tissue. The dual action formula also helps prevent food particles from getting underneath the denture during eating.
How do I apply Fixodent Plus Dual Power step by step?
Start by cleaning and drying your dentures. Apply small dots or short strips of cream to the fitting surface — do not spread it across the whole surface. Press the denture firmly into place, hold for a few seconds, and avoid eating or drinking for at least 15 minutes to allow the adhesive to set properly.
How long does the hold from Fixodent Plus Dual Power last?
Fixodent Plus Dual Power is designed to provide a secure hold for up to 12 hours from a single application. Results can vary depending on your individual denture fit, diet, and saliva levels. If you find the hold wearing off much sooner, it may be worth speaking to your dentist about your denture fit.
Does Fixodent Plus Dual Power contain zinc?
No — Fixodent Plus Dual Power Best Hold is completely zinc-free. This is an important safety consideration, as concerns were previously raised about neurological effects linked to excessive zinc ingestion from older denture adhesive formulations. The zinc-free formula makes it suitable for regular daily use.
Can I use Fixodent Plus Dual Power with partial dentures?
Yes, Fixodent Plus Dual Power is suitable for both full and partial removable dentures. Apply small dots of cream at the key fitting points of the partial denture rather than strips. Always use the minimum amount needed to achieve a comfortable hold.
What are the side effects of Fixodent Plus Dual Power?
Side effects are uncommon but can include mild gum irritation, a temporary change in taste, or slight discomfort if too much product is applied. Rarely, an allergic reaction may occur — if you notice swelling, itching, or a rash inside your mouth, stop use immediately and consult your pharmacist or GP.
How do I remove Fixodent Plus Dual Power adhesive from my dentures and gums?
To remove the denture, use a gentle rocking motion rather than pulling sharply. Soak the denture in warm water to loosen the adhesive residue, then brush it away with a soft denture brush. Rinse your mouth thoroughly with warm water to remove any adhesive remaining on your gums.
Is Fixodent Plus Dual Power suitable for sensitive gums?
The zinc-free formulation is generally well tolerated by people with sensitive gum tissue. However, if you have known allergies to any of the ingredients or have open sores or ulcers in your mouth, you should wait until these have healed before using any denture adhesive. If in doubt, speak to your pharmacist before use.
How much Fixodent Plus Dual Power should I use per application?
Use the minimum amount needed — typically three small strips or dots for an upper denture and two short strips for a lower denture. Using more than recommended does not improve the hold and may cause the cream to ooze into your mouth. Less is genuinely more with denture adhesive creams.
Who is eligible to use Fixodent Plus Dual Power?
This product is intended for adults aged 18 and over who wear removable full or partial dentures. It is not suitable for children, and it should not be used on broken or significantly ill-fitting dentures. People with allergies to any listed ingredients should avoid use and seek an alternative.
What happens if I accidentally swallow Fixodent Plus Dual Power?
Swallowing a small amount of adhesive cream during normal use is unlikely to cause harm, but the product is not intended to be ingested. If a large amount is swallowed — particularly by a child — contact NHS 111 or your nearest A&E for advice. Always keep the tube out of reach of children.
What are the alternatives to Fixodent Plus Dual Power?
Alternatives include other denture adhesive creams such as Poligrip and Corega, as well as denture adhesive strips or powders. The right choice depends on your denture type and personal preference. You can explore our oral health collection to compare available options.
How long can I keep using Fixodent Plus Dual Power?
Fixodent Plus Dual Power can be used daily as part of your regular denture care routine. However, if you find yourself relying heavily on adhesive to keep your dentures in place, this may indicate that your dentures need professional adjustment or replacement. Regular dental check-ups are recommended for all denture wearers.
What is the latest research on denture adhesive creams like Fixodent?
Research over the past decade has focused primarily on the safety of zinc-containing adhesives, leading most major brands — including Fixodent — to reformulate with zinc-free ingredients. Current evidence supports the safe daily use of zinc-free denture adhesive creams when applied as directed. The NHS recommends seeing a dentist if dentures feel persistently loose rather than relying solely on adhesive products.
How Should You Use Fixodent Plus Dual Power?
Using Fixodent Plus Dual Power correctly ensures you get the best possible hold throughout the day. Always start with clean, dry dentures — any moisture or residue on the fitting surface can reduce how well the adhesive bonds. Follow these steps each time you apply the cream.
What Is the Correct Dose of Fixodent Plus Dual Power?
The amount of adhesive you use matters. Using too much does not improve the hold — it simply causes excess cream to ooze into your mouth, which is uncomfortable and wasteful. The table below summarises the recommended application amounts by denture type.
When Is the Best Time to Use Fixodent Plus Dual Power?
Apply Fixodent Plus Dual Power first thing in the morning, after cleaning your dentures, before you eat breakfast or drink your morning cup of tea. This gives the adhesive time to activate and set before it is exposed to food or liquid. Applying it at the start of your day means you benefit from the full duration of hold throughout your waking hours.
Avoid applying the cream to wet dentures or immediately after rinsing, as excess moisture on the fitting surface can dilute the adhesive and reduce its effectiveness.
How Long Can You Use Fixodent Plus Dual Power For?
Fixodent Plus Dual Power can be used daily as part of your ongoing denture care routine. There is no set maximum duration of use, provided you are applying the correct amount and your dentures are otherwise well-fitting. However, if you find you are needing to use increasing amounts of adhesive to maintain a comfortable hold, this is a sign that your dentures may need professional adjustment or replacement — not more adhesive.
The NHS recommends that denture wearers attend regular dental check-ups to ensure their dentures continue to fit correctly as the shape of the jaw and gum tissue changes over time.
Do not exceed the recommended dose. If in doubt, speak to your pharmacist.
What Are the Most Common Side Effects of Fixodent Plus Dual Power?
For most people, Fixodent Plus Dual Power is well tolerated when used as directed. Side effects are uncommon, but it is worth knowing what to look out for. The most frequently reported issues are mild and tend to resolve on their own once you adjust your application technique or reduce the amount of cream used.
- Mild gum irritation or redness at the contact site
- Temporary altered or unusual taste in the mouth
- Slight discomfort or a sensation of excess product if too much cream is applied
- Mild nausea if a small amount of adhesive is accidentally swallowed
What Are the Less Common Side Effects of Fixodent Plus Dual Power?
Less commonly, some people may experience reactions that require them to stop using the product. These are not typical but should be taken seriously if they occur.
- Persistent gum soreness or inflammation that does not settle after a few days
- Swelling of the gum tissue or soft tissues inside the mouth
- Itching or a burning sensation inside the mouth
- Skin rash around the lips or mouth area
If you notice any of these symptoms, stop using the product immediately and consult your pharmacist or dentist before resuming use.
What Are the Serious Side Effects of Fixodent Plus Dual Power?
Serious side effects from this product are rare. However, a small number of people may experience an allergic reaction (hypersensitivity) to one or more of the ingredients. Signs of a serious allergic reaction include sudden swelling of the lips, tongue, or throat, difficulty breathing, or a widespread skin rash. This requires immediate medical attention — call 999 or go to your nearest A&E if you suspect a severe allergic reaction.
It is also worth noting that the product is zinc-free, which removes the risk of zinc toxicity that was associated with older denture adhesive formulations used in very large quantities over many years.
What Should You Do If You Experience Side Effects?
If you experience mild irritation, try reducing the amount of adhesive you apply and ensure your dentures are clean before each application. For persistent or worsening symptoms, stop use and speak to your pharmacist or GP. You do not need to visit A&E for mild reactions — your pharmacist can advise you on whether to continue, switch products, or seek further assessment.
Always report suspected side effects from medicines or medical devices to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.
Can Fixodent Plus Dual Power Interact With Other Medicines?
No clinically significant drug interactions are currently known for Fixodent Plus Dual Power. Because the product is applied topically to the denture surface and is not intended to be swallowed, systemic absorption is minimal and interactions with oral medications are not expected. If you are taking any prescribed medicines and have concerns, speak to your pharmacist for personalised advice before use.
If you are concerned about any side effects, contact your pharmacist or GP immediately.
Written and reviewed by our qualified team
Reviewed by:
Tarun Kumar
Superintendent/ Clinical Lead
📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.
Content last updated: 14 Sep 2026
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