Skip to product information
1 of 2

  • Images are for illustration purposes only

Fixodent Complete Original Denture Adhesive Cream

Fixodent Complete Original Denture Adhesive Cream

  • 1. Ozempic®️-equivalent therapy now available for weight management
  • 2. Average weight loss of 17%, with 1 in 3 patients achieving over 20%
  • 3. May help reduce osteoarthritis-related pain
  • 4. Wegovy®️ is not expected to impact the effectiveness of oral contraceptives
  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Holds full and partial dentures securely for up to 12 hours
  • ✔️ Zinc-free formula safe for daily denture use
  • ✔️ Prevents food particles from trapping under dentures
  • ✔️ Cushions gum tissue for improved denture comfort
  • ✔️ Suitable for both full and partial removable dentures

Price Checker

Regular price £22.99
Sale price £22.99
Sale Sold out
  • Lowest price guarantee
  • Includes FREE private prescription
View full details

 

What Is Fixodent Complete Original Denture Adhesive Cream?

 

Living with dentures doesn't have to mean worrying about them slipping at the wrong moment. Fixodent Complete Original denture adhesive cream is a well-established, zinc-free formula designed to hold full and partial dentures securely in place throughout the day. Whether you're eating, speaking, or simply going about your routine, a reliable denture fixative can make a real difference to your confidence and comfort. You can find this product and other oral health essentials in our dental products collection.

Denture adhesives are widely used by people who wear removable dentures. According to NHS guidance, even well-fitting dentures may benefit from an adhesive to improve stability — particularly in the early weeks of wearing a new set, or as the shape of your gums changes over time. Fixodent Complete Original is one of the most recognised names in this category in the UK.

 

How Does Fixodent Complete Original Work?

 

The mechanism is straightforward but effective. When you apply the cream to the fitting surface of your denture and press it against your gum tissue, the adhesive absorbs moisture from your saliva. This triggers a swelling and bonding reaction that creates a firm, cushioning seal between the denture base and the soft tissue of your mouth.

  • The polymer adhesive (PVM/MA copolymer and sodium carboxymethylcellulose) expands on contact with saliva
  • This expansion fills the microscopic gaps between the denture and gum surface
  • The resulting seal reduces movement and helps prevent food particles from becoming trapped underneath
  • The formula is zinc-free, removing the risk associated with excessive zinc absorption from older adhesive products

 

Who Should Use Fixodent Complete Original?

 

This product is intended for adults who wear removable full or partial dentures and want additional stability and comfort. It's particularly useful if your dentures feel loose, if you've recently had new dentures fitted, or if natural changes to your gum tissue have affected the fit over time. It is not a substitute for a properly fitted denture — if your dentures are significantly ill-fitting, you should see your dentist.

  • Adults wearing full upper or lower dentures
  • Adults wearing partial dentures who want extra security
  • People new to dentures who are still adjusting to wearing them
  • Those whose gum shape has changed, causing existing dentures to feel less secure

 

How Does Fixodent Complete Original Compare to Other Denture Adhesives?

 

Feature Fixodent Complete Original Poligrip Original
Zinc-free formula Yes Yes
Suitable for full dentures Yes Yes
Suitable for partial dentures Yes Yes
Flavour Neutral/mint Mint

 

Is Fixodent Complete Original Safe to Use Every Day?

 

Used as directed, this denture adhesive cream is considered safe for daily use. The zinc-free formulation addresses earlier concerns about excessive zinc intake from adhesive products used over long periods. That said, you should always use the minimum amount needed to achieve a comfortable hold — more product does not mean a better result, and excess adhesive can ooze into the mouth. If you're managing other aspects of your oral health, our oral health collection includes a range of complementary products.

Store the tube below 25°C with the cap tightly closed. Keep out of reach of children. This product is for external use in the mouth only — do not swallow.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Fixodent Complete Original Denture Adhesive Cream specifications
Treatment category Dental / Oral care
Mechanism of action Polymer adhesive absorbs saliva to form a cushioning seal between denture and gum tissue
Effective for Securing full and partial removable dentures
Suitable for Adults wearing removable dentures
Active ingredient PVM/MA copolymer, sodium carboxymethylcellulose (zinc-free)
Pack sizes 40 g, 47 g (varies by retailer)
UK classification General Sale List (GSL)
Preparation Cream
Route of administration Topical (applied to denture fitting surface)

Specifications of Fixodent Complete Original Denture Adhesive Cream

 

What Is Fixodent Complete Original and What Is It Used For?

 

Fixodent Complete Original is a topical denture adhesive cream used to improve the fit, stability, and comfort of removable full and partial dentures. It is applied directly to the fitting surface of the denture before insertion. The product is classified as a General Sale List (GSL) item in the UK, meaning it is available without a prescription. It is not a treatment for any dental disease — its purpose is mechanical: to reduce denture movement and improve the wearer's confidence during daily activities such as eating and speaking.

 

What Do You Need to Know Before Using Fixodent Complete Original?

 

Before using any denture adhesive, it's worth understanding when it is and isn't appropriate. Adhesive creams are not a long-term solution for poorly fitting dentures. If your dentures are causing pain, sores, or significant movement, you should consult your dentist rather than relying on adhesive alone.

Do not use this product if:

  • You are allergic to any of the ingredients, including PVM/MA copolymer or sodium carboxymethylcellulose
  • You have open sores, ulcers, or wounds on your gum tissue — seek dental advice first
  • Your dentures are broken or severely ill-fitting — see your dentist for adjustment or replacement
  • You are under 18 years of age — this product is intended for adults only

Warnings and precautions:

  • Use only the minimum amount needed — excess product can ooze into the mouth and be swallowed
  • Do not use as a substitute for professional dental care
  • If irritation, swelling, or an allergic reaction develops, discontinue use and seek advice from a pharmacist or dentist
  • Keep out of reach of children

Known drug interactions:

  • No clinically significant drug interactions are currently known for this product when used as directed

 

How Should You Use Fixodent Complete Original?

 

Correct application makes a significant difference to how well the adhesive performs. Using too much can cause the cream to ooze out from under the denture, while using too little may not provide adequate hold. Follow these steps each time you apply:

  1. Clean your dentures thoroughly and allow them to dry slightly — adhesive bonds better to a clean surface
  2. Apply small dots or short strips of cream to the fitting surface of the denture — do not spread it across the entire surface
  3. Press the denture firmly into position in your mouth and hold for a few seconds
  4. Bite down gently to ensure even distribution of the adhesive
  5. Avoid eating or drinking for at least 15 minutes after application to allow the seal to form
  6. At the end of the day, remove your dentures and clean away any remaining adhesive from both the denture and your gums
Indication Age Group Amount to Apply Frequency
Full denture stabilisation Adults (18+) Small dots or strips (pea-sized amounts) Once daily
Partial denture stabilisation Adults (18+) Smaller amounts — avoid clip areas Once daily

 

What Are the Possible Side Effects of Fixodent Complete Original?

 

Side effects from denture adhesive cream are uncommon when the product is used correctly. Most people tolerate it well. However, as with any product applied inside the mouth, some individuals may notice mild reactions — particularly if they are sensitive to any of the ingredients.

Common side effects:

  • Mild gum irritation or redness at the site of contact
  • Temporary altered or unusual taste in the mouth
  • Slight discomfort if excess adhesive contacts the soft palate or throat

Less common side effects:

  • Localised allergic reaction (redness, swelling, or itching of the gum tissue)
  • Nausea if a significant amount of adhesive is accidentally swallowed

If you experience any signs of a serious allergic reaction — such as swelling of the lips, tongue, or throat, or difficulty breathing — stop using the product immediately and seek urgent medical attention. For general pain or discomfort related to oral conditions, you may also find relevant products in our pain relief collection.

 

How Should You Store Fixodent Complete Original?

 

Proper storage keeps the adhesive effective and safe to use throughout its shelf life.

  • Store below 25°C in a cool, dry place
  • Keep the cap tightly closed after each use to prevent the cream from drying out
  • Do not store in direct sunlight or near a heat source
  • Keep out of reach and sight of children
  • Do not use after the expiry date printed on the tube or packaging
  • Do not freeze

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Fixodent Complete Original denture adhesive cream online in the UK?

You can buy Fixodent Complete Original online from Cured Pharmacy, a UK GPhC-registered online pharmacy. No prescription is needed — it is a General Sale List product available to adults. Browse our full range of dental products for related items.

How does Fixodent Complete Original denture adhesive cream work in the mouth?

The cream contains polymer adhesives — PVM/MA copolymer and sodium carboxymethylcellulose — that absorb moisture from saliva and swell to form a firm cushioning seal between the denture base and your gum tissue. This seal reduces movement and helps prevent food from getting trapped underneath. The effect typically lasts throughout the day with a single application.

How do I apply Fixodent Complete Original step by step?

Clean and dry your dentures first, then apply small dots or short strips of cream to the fitting surface — not the entire base. Press the denture firmly into place, hold for a few seconds, and avoid eating or drinking for at least 15 minutes. At the end of the day, remove your dentures and clean away any remaining adhesive from both the denture and your gums.

How long does Fixodent Complete Original hold dentures in place?

Fixodent Complete Original is designed to provide all-day hold, typically up to 12 hours from a single application. Results can vary depending on your diet, saliva flow, and how well your dentures currently fit. If you find the hold is consistently poor, it may be worth speaking to your dentist about the fit of your dentures.

Does Fixodent Complete Original contain zinc?

No — Fixodent Complete Original is zinc-free. Earlier versions of some denture adhesives contained zinc, which raised concerns about excessive zinc absorption with long-term daily use. The current formulation has been updated to remove zinc entirely, making it safer for regular use as directed.

Who is eligible to use Fixodent Complete Original?

This product is intended for adults aged 18 and over who wear removable full or partial dentures. It is not suitable for children, and it should not be used on broken or severely ill-fitting dentures without first consulting a dentist. People with known allergies to any of the listed ingredients should also avoid use.

What are the side effects of using Fixodent Complete Original?

Side effects are uncommon but can include mild gum irritation, a temporary change in taste, or — rarely — a localised allergic reaction such as redness or swelling of the gum tissue. If you experience swelling of the lips, tongue, or throat, stop use immediately and seek urgent medical attention. Most people use this product daily without any adverse effects.

How much Fixodent Complete Original should I use each time?

Use the minimum amount needed to achieve a comfortable hold — typically small dots or short strips applied to the fitting surface of the denture. Using too much can cause the cream to ooze out from under the denture into your mouth. More adhesive does not mean a stronger or longer-lasting hold.

Can I use Fixodent Complete Original with partial dentures?

Yes, Fixodent Complete Original is suitable for both full and partial dentures. When using it with a partial denture, apply small amounts carefully and avoid placing adhesive near the metal clasps or clip areas that attach to your natural teeth. If you are unsure, ask your dentist or pharmacist for guidance.

What happens if I accidentally swallow some Fixodent Complete Original?

Swallowing a small amount of adhesive that has mixed with saliva during normal use is unlikely to cause harm. However, deliberately swallowing the product or ingesting large amounts is not safe — seek medical advice if this occurs. Using the correct amount each time significantly reduces the risk of swallowing excess adhesive.

How do I remove Fixodent Complete Original from my dentures at the end of the day?

Remove your dentures as normal, then rinse them under warm (not hot) water to soften the adhesive. Use a soft-bristled denture brush to gently scrub away the remaining cream. Clean any adhesive residue from your gums using a damp cloth or soft toothbrush. Avoid using boiling water, as this can warp the denture material.

How long can I keep using Fixodent Complete Original?

There is no set maximum duration for using denture adhesive cream, provided you are using it correctly and your dentures are otherwise well-maintained. However, if you find you are relying on increasing amounts of adhesive to keep your dentures in place, this is a sign that your dentures may need to be relined or replaced — speak to your dentist. Regular dental check-ups are recommended even for denture wearers.

What are the alternatives to Fixodent Complete Original?

Other denture adhesive options include Fixodent Plus Best Hold, Poligrip Original, and Corega Extra Strong. Each product has a slightly different formulation and texture, so personal preference plays a role. Your dentist can advise which type of adhesive is most appropriate for your specific denture type and oral anatomy. You can also explore our wider oral health collection for complementary products.

Is Fixodent Complete Original suitable for use after dental implants?

Fixodent Complete Original is designed for use with removable dentures, not dental implants. If you have implant-retained dentures (overdentures), speak to your dentist before using any adhesive product, as the requirements for implant-supported prostheses differ from those for conventional removable dentures.

What are the latest findings on denture adhesive safety?

The main historical safety concern with denture adhesives related to zinc content in older formulations, which was linked to excessive zinc absorption and associated neurological effects with very heavy, prolonged use. Current zinc-free formulations like Fixodent Complete Original address this concern. Regulatory bodies including the MHRA have reviewed denture adhesive safety, and zinc-free products used as directed are considered safe for daily use in adults.

How Should You Use Fixodent Complete Original?

Before applying Fixodent Complete Original, make sure your dentures are clean and as dry as possible — adhesive bonds more effectively to a clean surface. Remove any old adhesive residue from both the denture and your gums before each new application.

If adhesive oozes out from under the denture after insertion, you have used too much. Reduce the amount at the next application.

What Is the Correct Dose of Fixodent Complete Original?

There is no fixed "dose" in the traditional sense — the amount you use depends on the size and type of your denture. The key principle is to use the minimum amount needed to achieve a comfortable, secure hold. Using more than necessary does not improve the hold and can cause excess adhesive to enter the mouth.

When Is the Best Time to Use Fixodent Complete Original?

Apply Fixodent Complete Original in the morning, after cleaning your dentures, before you insert them for the day. This gives the adhesive time to form a proper seal before you eat or drink. Avoid applying the cream immediately before consuming hot liquids, as heat can affect the adhesive's performance.

If you remove your dentures during the day for any reason, clean away the old adhesive before reapplying a fresh, small amount. Do not simply add more cream on top of existing adhesive residue.

How Long Can You Use Fixodent Complete Original For?

Fixodent Complete Original can be used daily on an ongoing basis, provided your dentures are otherwise well-maintained and professionally reviewed. There is no defined maximum treatment duration for this product when used as directed. However, if you find you need increasing amounts of adhesive to keep your dentures stable, this suggests the fit may have changed — book an appointment with your dentist for a review.

Regular dental check-ups are recommended even for full denture wearers, as gum tissue continues to change shape over time. Your dentist can assess whether your dentures need relining, rebasing, or replacing.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)

What Are the Most Common Side Effects of Fixodent Complete Original?

Most people who use Fixodent Complete Original as directed do not experience any significant side effects. The product is well tolerated for daily use. That said, because it is applied inside the mouth — a sensitive area — some individuals may notice mild reactions, particularly when first using the product or if they use more than the recommended amount.

  • Mild gum irritation or redness at the contact site
  • Temporary altered or unusual taste in the mouth
  • Slight discomfort if excess adhesive contacts the soft palate or back of the throat

What Are the Less Common Side Effects of Fixodent Complete Original?

Less common reactions are rare but possible, particularly in people who are sensitive to any of the ingredients. If you notice any of the following, stop using the product and seek advice from your pharmacist or dentist.

  • Localised allergic reaction — redness, swelling, or itching of the gum tissue or oral mucosa
  • Nausea if a significant amount of adhesive is accidentally swallowed
  • Persistent mouth soreness that does not resolve after stopping use

What Are the Serious Side Effects of Fixodent Complete Original?

Serious side effects are very uncommon with this product when used correctly. The most significant risk historically associated with denture adhesives was excessive zinc absorption from zinc-containing formulations — Fixodent Complete Original is zinc-free, which removes this concern. However, a severe allergic reaction (anaphylaxis), though extremely rare, is theoretically possible with any topically applied product.

Signs of a serious allergic reaction include sudden swelling of the lips, tongue, or throat, difficulty breathing or swallowing, a widespread skin rash, or dizziness. If you experience any of these symptoms, stop using the product immediately and call 999 or go to your nearest A&E department.

What Should You Do If You Experience Side Effects?

For mild side effects such as gum irritation or taste changes, try reducing the amount of adhesive you apply. Often, using less product resolves these issues without needing to stop use entirely. Clean your gums and dentures thoroughly each evening to prevent adhesive build-up, which can contribute to irritation over time.

If side effects persist after reducing the amount used, or if you develop any signs of an allergic reaction, discontinue use and speak to your pharmacist or dentist. Do not continue using the product if it is causing you discomfort.

Can Fixodent Complete Original Interact With Other Medicines?

No clinically significant drug interactions are currently known for Fixodent Complete Original when used as directed. Because it is applied topically inside the mouth and is not intended to be swallowed, systemic absorption is minimal and interactions with oral medications are not expected. If you are taking any medicines and are concerned, speak to your pharmacist before use.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

We’re a safe and
regulated UK service

Registered Pharmacy Badge

Lowest Price Guarantee

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

100% discreet packaging

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

Agent

Need help?
Talk to our friendly experts now

How our service works

Service Setup

Service setup

Discreet Packaging

Discreet packaging

Express Delivery

Express delivery