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Curanail 5% Medicated Fungal Nail Lacquer - 3ml

Curanail 5% Medicated Fungal Nail Lacquer - 3ml

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  • ✔️ Treats mild to moderate fungal nail infections in adults
  • ✔️ Contains 5% amorolfine to target fungal cell membranes
  • ✔️ Applied just once or twice weekly for convenience
  • ✔️ Suitable for both fingernail and toenail infections
  • ✔️ Available over the counter without a prescription

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What Is Curanail 5% Fungal Nail Lacquer?

 

Fungal nail infections are more common than you might think. In fact, they affect roughly 3% of the UK population at any one time, and they can be surprisingly stubborn to shift. If you've noticed your nail becoming thickened, discoloured, or brittle, you're not alone — and there is a clinically recognised treatment available without a prescription. Fungal nail lacquer in the form of Curanail 5% is a medicated topical solution containing amorolfine hydrochloride, an antifungal agent licensed for use in adults with mild to moderate onychomycosis (fungal nail infection). You can browse our full range of athletes foot and fungal infection treatments if you're dealing with related conditions alongside a nail infection.

Curanail 5% comes in a 3ml bottle and is applied directly to the affected nail using the spatula provided. It's designed for once or twice weekly application, making it a practical option for people who want an effective treatment that fits around a busy routine.

 

How Does Curanail 5% Medicated Nail Lacquer Work?

 

Amorolfine, the active ingredient in Curanail, works by targeting the fungal cell membrane. It inhibits two key enzymes — delta-14 reductase and delta-7-8 isomerase — that are essential for the biosynthesis of ergosterol, a sterol critical to fungal cell membrane integrity. Without ergosterol, the fungal cell membrane becomes structurally compromised, leading to cell death.

  • Amorolfine penetrates the nail plate and reaches the nail bed where the infection resides
  • It disrupts ergosterol synthesis, weakening the fungal cell membrane
  • Fungal cells are unable to replicate and eventually die
  • As the nail grows out, healthy nail tissue replaces the infected area

The lacquer formulation is specifically designed to adhere to the nail surface and maintain therapeutic concentrations of amorolfine within the nail plate between applications — which is why once or twice weekly dosing is sufficient.

 

Who Should Use Curanail 5% Nail Lacquer?

 

Curanail is suitable for adults aged 18 and over who have a mild to moderate fungal nail infection. It is most effective when the infection has not spread to the base (matrix) of the nail and when no more than two nails are affected. If you're unsure whether your nail condition is fungal in origin, it's worth speaking to a pharmacist or GP before starting treatment.

  • Adults aged 18 and over with confirmed or suspected onychomycosis
  • People with mild to moderate infection not involving the nail matrix
  • Those with up to two affected nails
  • Individuals looking for a once or twice weekly topical treatment option

 

How Does Curanail Compare to Other Fungal Nail Treatments?

 

Feature Curanail 5% Lacquer Oral Terbinafine (Prescription)
Active ingredient Amorolfine 5% Terbinafine 250mg
Route of administration Topical (nail) Oral (tablet)
Prescription required? No — available OTC Yes
Suitable for mild to moderate infection? Yes Yes (also severe)
Systemic side effects? Minimal — localised only Possible (liver, GI)

 

How Should You Store Curanail and Is It Suitable for Long-Term Use?

 

Curanail should be stored below 30°C, away from direct heat and sunlight. Keep the bottle tightly closed when not in use, and always store it out of reach of children. The lacquer is flammable, so it must be kept away from naked flames and sources of ignition — this includes not using it near lit candles or gas hobs.

Treatment with this fungal nail lacquer typically continues for six months for fingernails and up to nine to twelve months for toenails, reflecting the slow growth rate of nails. Consistency is key — missing applications regularly can reduce effectiveness. If you're also managing skin conditions alongside your nail infection, our foot care collection includes a range of complementary products.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Curanail 5% Medicated Fungal Nail Lacquer 3ml specifications
Treatment category Antifungal / Nail infection
Active ingredient Amorolfine hydrochloride 5% w/v
Mechanism of action Inhibits ergosterol biosynthesis in fungal cell membranes
Effective against Dermatophytes, some yeasts and moulds causing onychomycosis
Suitable for Adults aged 18 and over
Pack size 3ml
Strength 5% w/v
UK classification Pharmacy (P) medicine
Drug class Morpholine antifungal
Preparation Medicated nail lacquer
Route of administration Topical (nail)

Specifications of Curanail 5% Medicated Fungal Nail Lacquer 3ml

 

What Is Curanail 5% and What Is It Used For?

 

Curanail 5% Medicated Fungal Nail Lacquer is an over-the-counter antifungal treatment used to treat mild to moderate onychomycosis — the medical term for a fungal nail infection. It contains amorolfine hydrochloride at a concentration of 5% w/v. Onychomycosis most commonly affects the toenails, though fingernails can also be involved. The infection is typically caused by dermatophyte fungi, though yeasts and non-dermatophyte moulds can also be responsible. Symptoms include nail thickening, yellowing, crumbling, and separation from the nail bed.

Curanail is applied directly to the affected nail as a lacquer, once or twice weekly, and is intended for use in adults aged 18 and over. It is not a treatment for severe infections involving the nail matrix or more than two nails — in those cases, a GP referral for oral antifungal therapy may be more appropriate.

 

What Do You Need to Know Before Using Curanail 5%?

 

Before starting treatment, it's important to check whether Curanail is appropriate for you. Do not use this product if any of the following apply:

  • You are allergic to amorolfine or any other ingredient in the lacquer
  • You are under 18 years of age
  • The infection involves the base (matrix) of the nail
  • More than two nails are affected — seek GP advice instead
  • You are pregnant or breastfeeding (consult your GP or pharmacist first)
  • You have diabetes or a condition affecting circulation in your feet — always seek medical advice before self-treating nail infections

There are no well-documented significant drug interactions with topical amorolfine at therapeutic doses. However, you should be aware of the following precautions:

  • Avoid contact with eyes, ears, nose, and mucous membranes
  • Do not apply to broken or inflamed skin surrounding the nail
  • The lacquer is flammable — keep away from naked flames until fully dry
  • Remove nail varnish and artificial nails before use
  • Avoid inhaling fumes — use in a well-ventilated area

 

How Should You Use Curanail 5% Nail Lacquer?

 

Correct application is essential for the treatment to work. Follow these steps carefully each time you apply Curanail:

  1. File down the affected nail as much as possible using the nail file provided — this helps the lacquer penetrate the nail plate
  2. Clean the nail surface thoroughly using one of the alcohol swabs included in the pack
  3. Allow the nail to dry completely before applying the lacquer
  4. Dip the spatula into the bottle and apply the lacquer evenly over the entire surface of the affected nail, including the edges
  5. Allow the lacquer to dry for approximately three to five minutes before touching anything
  6. Clean the spatula with the alcohol swab after use and replace the cap tightly
  7. Repeat once or twice weekly throughout the full treatment course
Indication Age Group Dose Frequency
Mild to moderate fungal nail infection Adults 18+ Apply to entire nail surface Once or twice weekly
Children under 18 Not applicable Not recommended Not recommended

 

What Are the Possible Side Effects of Curanail 5%?

 

Like all medicines, Curanail can cause side effects, although not everyone experiences them. Most side effects are localised to the application site and are generally mild. If you experience anything that concerns you, stop using the product and speak to a pharmacist or GP. You can also find general guidance on managing skin reactions in our skin care collection.

Common side effects (may affect up to 1 in 10 people):

  • Mild burning or stinging sensation at the nail site
  • Itching around the treated nail
  • Nail discolouration

Less common side effects (may affect up to 1 in 100 people):

  • Skin irritation or redness around the nail fold
  • Nail brittleness or changes in nail texture
  • Contact dermatitis (allergic skin reaction) — stop use immediately if this occurs

 

How Should You Store Curanail 5% Medicated Lacquer?

 

Proper storage helps maintain the effectiveness of the product throughout your treatment course. If you're also using other topical treatments, our creams and ointments collection has further guidance on storage best practice for topical medicines.

  • Store below 30°C — do not refrigerate
  • Keep the bottle tightly closed when not in use
  • Store away from direct sunlight and heat sources
  • Keep out of reach and sight of children
  • Do not use after the expiry date printed on the label
  • The lacquer is flammable — keep away from naked flames and sources of ignition at all times
  • Do not dispose of via wastewater or household waste — return unused medicine to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Curanail 5% fungal nail lacquer online in the UK?

You can buy Curanail 5% Medicated Fungal Nail Lacquer directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for £21.99. It is available without a prescription as a Pharmacy (P) medicine for adults aged 18 and over. No GP appointment is needed — simply add it to your basket and complete a short eligibility check at checkout.

How does Curanail 5% fungal nail lacquer work in the body?

Curanail contains amorolfine, which works by inhibiting two enzymes — delta-14 reductase and delta-7-8 isomerase — that fungi need to produce ergosterol, a key component of their cell membranes. Without ergosterol, the fungal cell membrane breaks down and the organism cannot survive or replicate. The lacquer formulation allows amorolfine to penetrate the nail plate and reach the nail bed where the infection lives.

How do I use Curanail 5% step by step?

Start by filing the affected nail down as much as possible, then clean it with the alcohol swab provided. Apply the lacquer evenly over the entire nail surface using the spatula, allow it to dry for three to five minutes, then clean the spatula with the swab and replace the cap. Repeat this process once or twice weekly throughout your full treatment course.

How long does Curanail take to clear a fungal nail infection?

Treatment typically takes six months for fingernails and nine to twelve months for toenails, because nails grow slowly and the infected nail must fully grow out and be replaced by healthy tissue. You should continue applying the lacquer consistently throughout this period, even if the nail starts to look better earlier. Stopping treatment too soon is one of the most common reasons fungal nail infections return.

What are the side effects of Curanail 5% nail lacquer?

Side effects are uncommon and usually mild, limited to the area of application. You may notice a brief burning or itching sensation after applying the lacquer, or some discolouration of the nail. Rarely, skin irritation or contact dermatitis can occur around the nail fold — if this happens, stop using the product and speak to a pharmacist or GP.

Who is eligible to use Curanail 5% medicated nail lacquer?

Curanail is suitable for adults aged 18 and over who have a mild to moderate fungal nail infection affecting no more than two nails, where the infection has not reached the base of the nail. It is not recommended for children, and people who are pregnant, breastfeeding, diabetic, or have poor circulation should consult a GP or pharmacist before use. You can explore our wider range of fungal infection treatments if Curanail is not suitable for you.

What happens if I miss a dose of Curanail?

If you miss a weekly application, simply apply the lacquer as soon as you remember and then return to your regular once or twice weekly schedule. Do not apply a double dose to compensate for a missed application. Consistency matters with this treatment, so try to set a reminder on your phone to help you stay on track.

Can I use nail varnish while using Curanail?

No — you should remove all nail varnish and artificial nails before applying Curanail, as these can prevent the lacquer from penetrating the nail plate effectively. Between applications, it is best to avoid applying cosmetic nail products to the treated nail. Keeping the nail clean and free from other coatings gives the amorolfine the best chance of reaching the infection.

Is Curanail 5% safe to use during pregnancy or breastfeeding?

Curanail is not recommended for use during pregnancy or breastfeeding without first consulting a GP or pharmacist, as there is insufficient safety data to confirm it is risk-free in these situations. Your healthcare provider can advise on the most appropriate course of action. Do not self-treat a fungal nail infection during pregnancy without professional guidance.

What are the alternatives to Curanail for fungal nail infections?

Alternatives to Curanail include other topical antifungal nail lacquers, as well as oral antifungal tablets such as terbinafine or itraconazole, which are available on prescription and may be more appropriate for severe or widespread infections. Your GP or pharmacist can help you decide which option suits your situation best. You can also browse our foot care collection for complementary products.

How long can you use Curanail 5% for?

You should use Curanail for as long as it takes for the infected nail to fully grow out and be replaced by healthy nail — this is typically six months for fingernails and up to twelve months for toenails. Do not stop treatment early, even if the nail appears to be improving. If there is no improvement after three months of consistent use, speak to your GP.

Can Curanail be used on both fingernails and toenails?

Yes, Curanail can be used on both fingernails and toenails affected by fungal infection. The treatment duration differs between the two — fingernails typically require around six months of treatment, while toenails may need nine to twelve months due to their slower growth rate. The application method is the same for both.

Is Curanail 5% available without a prescription in the UK?

Yes, Curanail 5% is classified as a Pharmacy (P) medicine in the UK, meaning it is available without a prescription from a registered pharmacy. At Cured Pharmacy, you can purchase it online after completing a brief eligibility check to ensure it is appropriate for you. No GP visit is required for mild to moderate fungal nail infections in adults.

What does the latest research say about amorolfine nail lacquer?

Clinical evidence supports the use of amorolfine 5% nail lacquer as an effective topical treatment for mild to moderate onychomycosis, with studies demonstrating mycological cure rates when used consistently over the recommended treatment period. The BNF and NHS both recognise amorolfine as a first-line topical option for suitable patients. Research also suggests that combining amorolfine lacquer with oral antifungals may improve outcomes in more extensive infections, though this requires medical supervision.

How should I store Curanail 5% medicated nail lacquer?

Store Curanail below 30°C, away from direct sunlight and heat sources, with the cap tightly closed after each use. Keep it out of reach of children at all times. The lacquer is flammable, so never use or store it near naked flames, and do not dispose of it in household waste — return any unused product to your local pharmacy for safe disposal.

How Should You Use Curanail 5% Medicated Fungal Nail Lacquer?

Applying Curanail correctly makes a real difference to how well it works. Before each application, remove any existing nail varnish or artificial nails from the affected nail. Then follow these steps carefully:

Wash your hands after application. Avoid contact with eyes, ears, and mucous membranes. The lacquer is flammable — do not use near naked flames or lit cigarettes until it has dried completely.

What Is the Correct Dose of Curanail 5%?

The dose of Curanail is determined by the frequency of application rather than the quantity used — you should apply enough lacquer to cover the entire nail surface evenly in a single coat. There is no benefit to applying multiple coats in one session.

When Is the Best Time to Use Curanail 5%?

There is no strict time of day requirement for applying Curanail, but many people find it easiest to apply in the evening before bed. This allows the lacquer to dry fully overnight without the risk of it being disturbed by footwear, socks, or daily activities. Choosing a consistent day or days each week — for example, every Sunday evening, or every Wednesday and Sunday — can help you maintain the regular schedule that this treatment requires.

Avoid applying the lacquer immediately before showering, bathing, or swimming, as moisture can affect adhesion. If you do get the treated nail wet shortly after application, allow it to dry thoroughly before your next scheduled application.

How Long Can You Use Curanail 5% For?

Treatment duration depends on which nails are affected. Fingernails typically require around six months of consistent treatment, while toenails — which grow more slowly — may need nine to twelve months. You should continue using Curanail until the infected nail has fully grown out and been replaced by healthy nail tissue, even if the nail appears to be improving before that point.

If you see no improvement after three months of regular use, stop treatment and consult your GP, as you may need a different approach such as oral antifungal therapy. Do not use Curanail for longer than twelve months without seeking medical advice.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Curanail 5%?

Most people who use Curanail do not experience significant side effects. When they do occur, they are usually mild and confined to the area of application. Common side effects may affect up to 1 in 10 people and include:

  • A brief burning or stinging sensation immediately after applying the lacquer
  • Itching around the treated nail
  • Nail discolouration (the nail may appear slightly yellowed or altered in colour)

These effects are generally short-lived and do not usually require you to stop treatment. If they persist or worsen, speak to a pharmacist for advice.

What Are the Less Common Side Effects of Curanail 5%?

Less common side effects may affect up to 1 in 100 people. These are still localised to the nail and surrounding skin, but may be more noticeable:

  • Redness or inflammation of the skin around the nail fold (paronychia-like reaction)
  • Nail brittleness or changes in nail texture during treatment
  • Skin dryness or peeling around the treated nail
  • A sensation of nail pain or tenderness

If any of these effects are troublesome or do not resolve, it is worth checking in with your pharmacist before continuing treatment.

What Are the Serious Side Effects of Curanail 5%?

Serious side effects with Curanail are rare, but you should be aware of them. Contact dermatitis — an allergic skin reaction — can occasionally occur, presenting as significant redness, swelling, blistering, or intense itching around the nail or on the surrounding skin. If you develop any signs of an allergic reaction, including rash, facial swelling, or difficulty breathing, stop using the product immediately and seek urgent medical attention. These reactions are uncommon but require prompt assessment.

What Should You Do If You Experience Side Effects of Curanail?

For mild side effects such as brief stinging or itching, no specific action is usually needed — simply allow the lacquer to dry fully and monitor the area. If you experience persistent irritation, skin redness, or any signs of an allergic reaction, stop using Curanail and consult your pharmacist or GP. You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. Do not ignore worsening symptoms around the nail, as secondary bacterial infection can occasionally develop in skin that has been irritated.

Can Curanail 5% Interact With Other Medicines?

There are no well-documented clinically significant drug interactions with topical amorolfine at the doses used in Curanail. Because the medicine is applied to the nail surface and absorption into the bloodstream is minimal, systemic interactions are considered unlikely. However, if you are taking any prescription medicines or have an underlying health condition, it is always sensible to check with your pharmacist before starting a new treatment. This is particularly relevant if you are using other topical products on or near the same area.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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