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Colpermin IBS Relief

Colpermin IBS Relief

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  • ✔️ Relieves IBS cramps, bloating, and trapped wind effectively
  • ✔️ Gastro-resistant capsules target the intestine directly
  • ✔️ Contains 187mg peppermint oil per capsule for antispasmodic action
  • ✔️ Suitable for adults and young people aged 15 and over
  • ✔️ OTC medicine — no prescription required for convenient access

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What Are Peppermint Oil Capsules for IBS?

 

If you live with irritable bowel syndrome, you'll know how disruptive it can be. The cramping, the bloating, the unpredictable bouts of trapped wind — it affects your day in ways that are hard to explain to anyone who hasn't experienced it. Colpermin IBS Relief offers a clinically recognised option for managing these symptoms. Each gastro-resistant capsule contains 187 mg of peppermint oil, carefully formulated to pass through the stomach intact and release its active ingredient directly in the intestine, where it's needed most. IBS affects around one in five people in the UK at some point in their lives, according to the NHS, making it one of the most common gut conditions seen in primary care. You can explore our full range of IBS and cramps treatments if you're looking for additional support alongside Colpermin.

 

How Does Colpermin IBS Relief Work?

 

Peppermint oil contains a compound called menthol, which acts as a natural antispasmodic. Put simply, it helps the smooth muscle of the bowel wall to relax. When that muscle is in spasm — which is what causes the cramping and pain in IBS — peppermint oil can ease that tension and reduce discomfort. The gastro-resistant coating on each capsule is key. Without it, the oil would be released in the stomach, potentially causing heartburn. The coating ensures the oil reaches the small intestine and colon, where it can work directly on the gut muscle.

  • Menthol in peppermint oil blocks calcium channels in smooth muscle cells, reducing spasm
  • Gastro-resistant capsule shell protects the oil from stomach acid
  • Oil is released in the intestine, targeting the source of IBS cramps
  • Reduces bowel hypersensitivity, which contributes to pain and urgency in IBS

 

Who Is Colpermin IBS Relief Suitable For?

 

Colpermin is intended for adults and young people aged 15 and over who have already received a diagnosis of irritable bowel syndrome from a healthcare professional. It's particularly useful if your main symptoms are abdominal cramps, bloating, and trapped wind. It is not a treatment for the underlying cause of IBS — rather, it helps manage the day-to-day symptoms that affect your quality of life.

  • Adults aged 15 and over with confirmed IBS
  • People experiencing abdominal cramps, bloating, or trapped wind
  • Those who prefer a non-prescription, plant-derived option
  • Individuals who have not responded adequately to dietary changes alone

It is not suitable for children under 15, people with known hypersensitivity to peppermint or menthol, or those with achlorhydria (absence of stomach acid). Always read the label before use.

 

How Does Colpermin Compare to Other IBS Antispasmodics?

 

Feature Colpermin IBS Relief Mebeverine (Colofac)
Active ingredient Peppermint oil 187 mg Mebeverine hydrochloride 135 mg
Mechanism Natural antispasmodic (menthol) Synthetic antispasmodic
Suitable for Adults and young people 15+ Adults 18+
OTC availability Yes Yes

 

How Should You Store Colpermin and Is It Clinically Suitable for You?

 

Store Colpermin IBS Relief below 25°C in a dry place, away from direct sunlight and out of the reach of children. Do not use the capsules after the expiry date printed on the pack. If you are pregnant, breastfeeding, or managing another gastrointestinal condition alongside IBS, speak to your GP or pharmacist before starting peppermint oil capsules for IBS. It's also worth checking whether any other medicines you take could be affected — though no significant drug interactions have been established at therapeutic doses for this product. If you're also dealing with constipation as part of your IBS, our constipation treatments range may offer complementary support.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Colpermin IBS Relief specifications
Treatment category Irritable bowel syndrome (IBS)
Mechanism of action Antispasmodic — relaxes intestinal smooth muscle via menthol-mediated calcium channel blockade
Effective for Abdominal cramps, bloating, trapped wind associated with IBS
Suitable for Adults and young people aged 15 and over
Active ingredient Peppermint oil 187 mg per capsule
Pack sizes 20 capsules, 100 capsules
Strengths 187 mg peppermint oil (equivalent to 100 mg menthol)
UK classification General Sale List (GSL) / Pharmacy (P) medicine
Drug class Antispasmodic
Preparation Gastro-resistant capsules
Route of administration Oral

Specifications of Colpermin IBS Relief

 

What Is Colpermin IBS Relief and What Is It Used For?

 

Colpermin IBS Relief is an antispasmodic medicine used to relieve the symptoms of irritable bowel syndrome in adults and young people aged 15 and over. Each gastro-resistant capsule contains 187 mg of peppermint oil as the active ingredient. The capsules are designed to pass through the stomach without dissolving, releasing the peppermint oil in the intestine where it can act directly on the bowel muscle. Colpermin is used to treat abdominal pain and cramping, bloating, and trapped wind — the three symptoms that most commonly affect people with IBS on a day-to-day basis. It does not cure IBS, but it can make living with it considerably more manageable.

 

What Do You Need to Know Before Using Colpermin IBS Relief?

 

Before taking Colpermin, it's important to check whether it is appropriate for you. Do not take this medicine if any of the following apply:

  • You are under 15 years of age
  • You are allergic to peppermint oil, menthol, or any other ingredient in the capsule
  • You have achlorhydria (a condition where the stomach produces little or no acid)
  • You have not had your bowel symptoms assessed by a doctor — always get a diagnosis of IBS confirmed before self-treating

Speak to your doctor or pharmacist before taking Colpermin if you are pregnant or breastfeeding, as safety data in these groups is limited. Use with caution if you have a history of hiatus hernia or gastro-oesophageal reflux disease (GORD), as peppermint oil can occasionally relax the lower oesophageal sphincter and worsen reflux symptoms.

No clinically significant drug interactions have been established for Colpermin at standard therapeutic doses. However, if you are taking other medicines — particularly those with a narrow therapeutic index — always inform your pharmacist. If you're managing other digestive concerns alongside IBS, you may also find our indigestion treatments range helpful.

  • No established interactions with common OTC or prescription medicines at therapeutic doses
  • Inform your pharmacist of all medicines you are currently taking

 

How Should You Use Colpermin IBS Relief?

 

Always follow the instructions on the patient information leaflet inside the pack. The steps below summarise correct use for adults and young people aged 15 and over.

  1. Take one capsule 30 to 60 minutes before a meal
  2. Swallow the capsule whole with a full glass of water
  3. Do not chew, crush, or break the capsule — this destroys the gastro-resistant coating
  4. Take up to three capsules per day, each before a separate meal
  5. If symptoms do not improve after two to four weeks, consult your GP
Indication Age Group Dose Frequency
IBS cramps, bloating, trapped wind Adults and young people 15+ 1 capsule (187 mg peppermint oil) Up to 3 times daily, before meals
Not applicable Children under 15 Not recommended Not recommended

 

What Are the Possible Side Effects of Colpermin IBS Relief?

 

Like all medicines, Colpermin can cause side effects, although not everyone experiences them. Most side effects are mild and tend to resolve without any treatment. If you experience anything that concerns you, stop taking the capsules and speak to your pharmacist or GP.

Common side effects (may affect up to 1 in 10 people):

  • Heartburn or a burning sensation in the chest
  • Perianal irritation or a warm sensation around the back passage
  • Belching with a peppermint taste

Less common side effects (may affect up to 1 in 100 people):

  • Allergic reactions including skin rash, itching, or hives
  • Headache
  • Slowed heart rate (bradycardia) — very rare
  • Muscle tremor — very rare

If you develop signs of a serious allergic reaction — such as swelling of the face, lips, or throat, or difficulty breathing — seek emergency medical attention immediately.

 

How Should You Store Colpermin IBS Relief?

 

Correct storage helps maintain the quality and effectiveness of the capsules throughout their shelf life. Follow these guidelines:

  • Store below 25°C in a dry place
  • Keep away from direct sunlight and sources of heat
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the carton
  • Do not dispose of medicines via wastewater or household waste — return unused capsules to your pharmacy

If you're looking to support your overall gut health alongside Colpermin, our vitamins and supplements range includes options that may complement your digestive wellness routine.

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Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Colpermin IBS Relief online in the UK?

You can buy Colpermin IBS Relief online from Cured Pharmacy, a UK GPhC-registered online pharmacy. It is available without a prescription as an over-the-counter medicine. Browse our full IBS and cramps range for additional options to support your symptoms.

How does Colpermin IBS Relief work in the body?

Colpermin contains peppermint oil, which acts as a natural antispasmodic by relaxing the smooth muscle lining of the bowel wall. The menthol in peppermint oil blocks calcium channels in intestinal muscle cells, reducing painful spasms. This helps relieve the cramping, bloating, and trapped wind that are characteristic of IBS.

How do I take Colpermin IBS Relief step by step?

Take one capsule 30 to 60 minutes before each main meal, up to three times daily. Swallow the capsule whole with a full glass of water — never chew or crush it, as this breaks the gastro-resistant coating and may cause heartburn. If you are unsure, your pharmacist can walk you through the correct technique.

What is the correct dose of Colpermin IBS Relief for adults?

The recommended dose for adults and young people aged 15 and over is one capsule (187 mg peppermint oil) taken up to three times daily before meals. Do not exceed three capsules in any 24-hour period. If your symptoms are not improving after two to four weeks, speak to your GP.

What is the best time to take Colpermin IBS Relief?

The capsules should be taken 30 to 60 minutes before your main meals — typically before breakfast, lunch, and dinner. Taking them before eating allows the peppermint oil to reach the intestine and begin working before food triggers bowel activity. Consistency with timing tends to give the most reliable symptom relief.

What are the side effects of Colpermin IBS Relief and how do I manage them?

The most commonly reported side effects are heartburn, a burning sensation around the back passage, and belching with a peppermint taste. These are usually mild and short-lived. If heartburn is a problem, try taking the capsule slightly earlier before meals, and avoid lying down immediately after taking it.

Who is eligible to take Colpermin IBS Relief?

Colpermin is suitable for adults and young people aged 15 and over who have been diagnosed with irritable bowel syndrome by a healthcare professional. It is not suitable for children under 15, people with achlorhydria, or those with a known allergy to peppermint or menthol. Pregnant or breastfeeding individuals should consult their GP before use.

What happens if I miss a dose of Colpermin IBS Relief?

If you miss a dose, simply skip it and take your next capsule before your next meal as usual. Do not take a double dose to make up for a missed one. Colpermin works best when taken consistently before meals, so try to build it into your daily routine.

How long can you take Colpermin IBS Relief for?

Colpermin can be used continuously for up to three months. If your symptoms persist or worsen beyond this period, you should see your GP for further assessment. IBS is a long-term condition for many people, and your doctor can advise on ongoing management strategies including dietary changes and other treatments.

Can I take Colpermin IBS Relief if I am pregnant?

There is limited safety data on the use of peppermint oil capsules during pregnancy, so Colpermin is not routinely recommended without medical advice. If you are pregnant and experiencing IBS symptoms, speak to your GP or midwife before taking any new medicine. They can help you weigh up the potential benefits and risks.

Is Colpermin IBS Relief suitable for children?

No — Colpermin is not recommended for children under 15 years of age. If a child is experiencing symptoms that suggest IBS, a GP should be consulted for appropriate assessment and management. Self-treating bowel symptoms in children without a confirmed diagnosis is not advised.

What are the alternatives to Colpermin IBS Relief?

Other antispasmodic options available over the counter in the UK include mebeverine hydrochloride (Colofac) and hyoscine butylbromide (Buscopan). Dietary approaches such as a low-FODMAP diet are also recommended by the NHS for IBS management. Your pharmacist can help you decide which option suits your symptoms best — you can also explore our diarrhoea treatments if loose stools are part of your IBS pattern.

Can Colpermin IBS Relief cause heartburn?

Yes, heartburn is one of the most commonly reported side effects of peppermint oil capsules, occurring because menthol can relax the lower oesophageal sphincter. The gastro-resistant coating on Colpermin capsules is specifically designed to minimise this risk by preventing the oil from being released in the stomach. If heartburn persists, speak to your pharmacist about whether Colpermin is still the right choice for you.

Does Colpermin IBS Relief interact with other medicines?

No clinically significant drug interactions have been established for Colpermin at standard therapeutic doses. However, as with any medicine, it is good practice to inform your pharmacist of everything else you are taking — including herbal remedies and supplements. If you are on multiple medicines, a pharmacist medicines review can help identify any potential concerns.

What does the latest research say about peppermint oil for IBS?

Clinical evidence supports the use of peppermint oil as an antispasmodic for IBS, and it is included in NHS guidance on IBS treatment options. Multiple systematic reviews have found peppermint oil to be more effective than placebo in reducing abdominal pain in IBS. It is considered a well-tolerated first-line option for symptom management in appropriate patients.

How Should You Use Colpermin IBS Relief?

Colpermin IBS Relief capsules are straightforward to use, but the way you take them matters. The gastro-resistant coating is essential to how the medicine works, so it must remain intact when you swallow it. Follow these steps each time you take a capsule.

If you find swallowing capsules difficult, speak to your pharmacist — they may be able to suggest a technique or alternative formulation that suits you better.

What Is the Correct Dose of Colpermin IBS Relief?

The dose of Colpermin depends on your age. It is only licensed for use in adults and young people aged 15 and over. Always stick to the recommended dose and do not take more than three capsules in any 24-hour period, even if your symptoms feel particularly severe on a given day.

When Is the Best Time to Use Colpermin IBS Relief?

Timing is important with Colpermin. Taking each capsule 30 to 60 minutes before a meal gives the peppermint oil time to travel through the stomach and reach the intestine before food arrives and triggers bowel activity. Most people find it easiest to take a capsule before breakfast, lunch, and their evening meal. If you only experience symptoms at certain times of day, you can take fewer capsules — you don't have to take all three doses if your symptoms don't warrant it.

How Long Can You Use Colpermin IBS Relief For?

Colpermin can be used for up to three months continuously. Many people find their symptoms improve within the first two to four weeks of regular use. If you don't notice any improvement after two weeks, or if your symptoms worsen at any point, stop taking the capsules and consult your GP. IBS is a long-term condition, and your doctor can help you develop a broader management plan that may include dietary changes, stress management, and other treatments alongside or instead of Colpermin.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Colpermin IBS Relief?

Most people who take Colpermin IBS Relief tolerate it well, but some do experience side effects. The most frequently reported ones are related to the peppermint oil itself and tend to be mild. They usually settle on their own without any need to stop treatment.

  • Heartburn or a burning sensation in the chest
  • Perianal irritation — a warm or burning feeling around the back passage after a bowel movement
  • Belching with a peppermint taste or smell

Heartburn occurs because menthol can relax the lower oesophageal sphincter, allowing stomach acid to travel upwards. The gastro-resistant coating on Colpermin capsules is designed to reduce this risk, which is why it's so important not to chew or crush them.

What Are the Less Common Side Effects of Colpermin IBS Relief?

Less common side effects are reported by a smaller number of people and are generally not serious. If any of the following occur and are troubling you, speak to your pharmacist before continuing treatment.

  • Headache
  • Skin rash, itching, or hives (urticaria)
  • Nausea
  • Dizziness

These effects are uncommon and may not be directly caused by the medicine in every case. Keeping a note of when they occur — and whether they coincide with taking the capsule — can help your pharmacist or GP assess whether Colpermin is the cause.

What Are the Serious Side Effects of Colpermin IBS Relief?

Serious side effects with Colpermin are very rare, but you should be aware of them. A very small number of people have reported slowed heart rate (bradycardia) and muscle tremor, though these are exceptionally uncommon at standard doses. More importantly, allergic reactions — though rare — can occasionally be severe.

Seek emergency medical attention immediately if you experience any of the following:

  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Sudden drop in blood pressure or feeling faint
  • Severe skin reaction

What Should You Do If You Experience Side Effects of Colpermin IBS Relief?

If you experience mild side effects such as heartburn, try taking the capsule a little earlier before your meal and avoid lying down for at least 30 minutes after taking it. For perianal irritation, this usually resolves on its own and does not require treatment. If any side effect is persistent, worsening, or causing you significant distress, stop taking Colpermin and speak to your pharmacist or GP. You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Colpermin IBS Relief Interact With Other Medicines?

No clinically significant interactions between Colpermin and other medicines have been established at standard therapeutic doses. However, peppermint oil may theoretically affect the absorption of some medicines by altering gut motility. If you are taking medicines with a narrow therapeutic window — such as certain heart or epilepsy medicines — always inform your pharmacist before starting Colpermin. As a general rule, disclose all medicines, supplements, and herbal remedies you are taking whenever you start a new treatment.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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