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Cleen Ready to Use Enema - 133ml

Cleen Ready to Use Enema - 133ml

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  • ✔️ Relieves constipation with results in 2–5 minutes
  • ✔️ Sodium phosphate formula softens hard, impacted stools
  • ✔️ Pre-filled 133ml bottle — no measuring or mixing needed
  • ✔️ Suitable for adults and children aged 12 and over
  • ✔️ Effective for bowel preparation before medical procedures

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What Is a Phosphate Enema and How Does Cleen Work?

 

Constipation can be genuinely uncomfortable — and sometimes, oral laxatives simply do not act quickly enough. The phosphate enema has been used for decades as a reliable, fast-acting rectal solution for bowel evacuation. Cleen Ready to Use Enema 133ml contains sodium acid phosphate and sodium phosphate as its active ingredients, delivered in a pre-filled, single-use squeeze bottle that makes administration as straightforward as possible. If you are looking for effective relief from constipation or need to clear the bowel before a medical procedure, this product is worth understanding properly. You can also explore our wider range of constipation treatments if you want to compare options before deciding.

Cleen is a well-established brand in the UK, and this 133ml ready-to-use format means there is no mixing or measuring involved. The solution is administered rectally, and results are typically seen within 2 to 5 minutes. That speed of action is one of the main reasons healthcare professionals and patients alike reach for this product when prompt bowel clearance is needed.

 

How Does Cleen Ready to Use Enema Work in the Body?

 

The mechanism is based on osmosis. When the sodium phosphate solution is introduced into the rectum, it draws water from surrounding tissues into the bowel lumen. This increase in fluid volume softens the stool and distends the rectal wall, triggering the urge to defecate. It is a local action — the solution is not intended to be absorbed systemically in significant amounts at the recommended dose.

  • Sodium phosphate creates an osmotic gradient in the rectum
  • Water is drawn into the bowel, softening impacted stool
  • Rectal distension stimulates peristaltic contractions
  • Bowel movement typically occurs within 2–5 minutes

 

Who Should Use Cleen Ready to Use Enema?

 

This product is suitable for adults and children aged 12 and over who are experiencing constipation that has not responded to dietary changes or oral laxatives. It is also used for bowel preparation before certain medical examinations or procedures, where a clear bowel is required. If you are managing a digestive condition and want to explore related products, our IBS and cramps collection may also be relevant to you.

  • Adults with acute or short-term constipation
  • Patients requiring pre-procedural bowel clearance
  • Individuals for whom oral laxatives have been ineffective
  • Those aged 12 and over (under medical guidance for younger patients)

 

How Does Cleen Enema Compare to Other Constipation Treatments?

 

Feature Cleen Ready to Use Enema 133ml Oral Laxative (e.g. Lactulose)
Route of administration Rectal Oral
Onset of action 2–5 minutes 24–48 hours
Suitable for bowel prep Yes Sometimes (depends on procedure)
Single-use convenience Yes — pre-filled bottle Requires measuring doses

 

Is Cleen Ready to Use Enema Suitable for Long-Term Use?

 

This product is intended for short-term or occasional use only. Regular reliance on any enema — including a phosphate enema — can disrupt the natural balance of electrolytes in the body and may reduce the bowel's natural motility over time. If you find yourself needing to use it frequently, that is a signal to speak with your GP about the underlying cause of your constipation. Chronic constipation often has dietary, lifestyle, or medical causes that deserve proper investigation rather than repeated symptomatic treatment.

Store the product below 25°C and keep it out of reach of children. Do not refrigerate. Check the expiry date before use and do not use if the seal is broken.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Cleen Ready to Use Enema 133ml specifications
Treatment category Constipation / Bowel evacuation
Mechanism of action Osmotic laxative — draws water into the bowel lumen
Effective Within 2–5 minutes of rectal administration
Suitable for Adults and children aged 12 and over
Active ingredient Sodium acid phosphate and sodium phosphate
Pack size 133ml single-use bottle
UK classification General Sale / Pharmacy (P)
Drug class Osmotic laxative
Preparation Rectal solution
Route of administration Rectal

Specifications of Cleen Ready to Use Enema 133ml

 

What Is Cleen Ready to Use Enema and What Is It Used For?

 

Cleen Ready to Use Enema 133ml is a rectal solution containing sodium acid phosphate and sodium phosphate. It is used to relieve constipation when stools are hard, dry, or difficult to pass, and to prepare the bowel before certain medical examinations such as colonoscopy or sigmoidoscopy. The NHS recognises constipation as a very common condition, affecting around one in seven adults in the UK at any given time. This product offers a fast-acting, locally acting option when other approaches have not worked.

 

What Do You Need to Know Before Using Cleen Ready to Use Enema?

 

Before using this product, it is important to check whether it is appropriate for you. There are certain conditions and circumstances where use is not recommended without medical supervision.

Do not use this product if you:

  • Have kidney disease or impaired renal function
  • Have heart failure or significant cardiovascular disease
  • Have inflammatory bowel disease (such as Crohn's disease or ulcerative colitis)
  • Have a suspected or confirmed bowel obstruction
  • Are allergic to any of the ingredients
  • Have recently had bowel surgery
  • Are under 12 years of age (unless directed by a doctor)

Use with caution if you:

  • Are pregnant or breastfeeding — consult your GP or midwife first
  • Are elderly, as electrolyte disturbances may be more likely
  • Have a history of electrolyte imbalance

Known drug interactions:

  • Diuretics (water tablets) — may increase the risk of electrolyte imbalance
  • Medicines that affect kidney function — use with caution
  • Lithium — sodium changes may affect lithium levels; seek medical advice

 

How Should You Use Cleen Ready to Use Enema?

 

Always follow the instructions provided with the product. The enema is for rectal use only and should never be taken by mouth. Wash your hands before and after use.

  1. Remove the protective cap from the nozzle
  2. Lie on your left side with your right knee drawn up towards your chest
  3. Gently insert the lubricated nozzle into the rectum — do not force it
  4. Slowly squeeze the bottle to deliver the solution
  5. Retain the liquid for as long as comfortable before moving to the toilet
  6. Dispose of the empty bottle safely after single use
Indication Age Group Dose Frequency
Constipation relief Adults and children 12+ One 133ml bottle Once daily, short-term only
Bowel preparation Adults As directed by healthcare professional As instructed
Children under 12 Under 12 Not recommended without medical advice

 

What Are the Possible Side Effects of Cleen Ready to Use Enema?

 

Like all medicines, this product can cause side effects, although not everyone experiences them. Most side effects are mild and resolve quickly after use.

Common side effects:

  • Rectal discomfort or irritation
  • Abdominal cramping or bloating
  • A feeling of urgency to open the bowels

Less common side effects:

  • Electrolyte disturbances (particularly with repeated use) — symptoms may include muscle weakness, irregular heartbeat, or unusual thirst
  • Rectal bleeding — stop use and seek medical advice if this occurs
  • Nausea

If you experience any serious symptoms such as chest pain, severe abdominal pain, or signs of an allergic reaction (swelling, difficulty breathing, rash), stop use immediately and seek emergency medical attention. You can also browse our haemorrhoids and piles range if rectal discomfort is an ongoing concern alongside constipation.

 

How Should You Store Cleen Ready to Use Enema?

 

  • Store below 25°C in a dry place
  • Do not refrigerate or freeze
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the packaging
  • Do not use if the seal is broken or the bottle appears damaged
  • Dispose of the used bottle responsibly — do not flush

If you are managing ongoing digestive health concerns, our diarrhoea treatments collection may also be useful to have to hand, as bowel habits can sometimes swing in either direction.

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Frequently Asked Questions

Where can I buy Cleen Ready to Use Enema online in the UK?

You can buy Cleen Ready to Use Enema 133ml directly from Cured Pharmacy, a UK GPhC-registered online pharmacy, for £6.19. No prescription is required, and it is dispatched discreetly to your home address. Simply add it to your basket and complete checkout in a few minutes.

How does a phosphate enema work in the body?

A phosphate enema works by osmosis — the sodium phosphate solution draws water from the surrounding rectal tissue into the bowel lumen. This softens hard stool and distends the rectal wall, triggering the urge to defecate. The action is local rather than systemic, meaning it works directly in the rectum rather than being absorbed into the bloodstream in significant amounts.

How do I use Cleen Ready to Use Enema step by step?

Follow these steps for correct administration:

  1. Wash your hands thoroughly before starting
  2. Remove the protective cap from the nozzle
  3. Lie on your left side with your right knee bent towards your chest
  4. Gently insert the nozzle into the rectum — never force it
  5. Squeeze the bottle slowly and steadily to release the solution
  6. Retain the liquid as long as comfortable, then go to the toilet

Always read the patient information leaflet included in the pack before use.

How long does it take for Cleen enema to work?

Cleen Ready to Use Enema typically produces a bowel movement within 2 to 5 minutes of administration. Because of this rapid onset, you should stay close to a toilet after using it. If no result occurs within 30 minutes, do not use a second dose without speaking to a pharmacist or GP first.

What is the correct dose of Cleen Ready to Use Enema?

For adults and children aged 12 and over, the standard dose is one 133ml bottle used rectally on a single occasion. It should not be used more than once daily, and only for short-term relief. If you are using it for bowel preparation before a medical procedure, follow the specific instructions given by your healthcare team.

Who should not use Cleen Ready to Use Enema?

This product is not suitable for everyone. Do not use it if you have any of the following:

  • Kidney disease or impaired renal function
  • Heart failure or significant cardiovascular conditions
  • Inflammatory bowel disease (Crohn's or ulcerative colitis)
  • Suspected bowel obstruction
  • Recent bowel surgery

Children under 12 should only use this product under direct medical supervision.

Can I use Cleen enema if I am pregnant?

If you are pregnant, you should consult your GP or midwife before using any enema product, including Cleen. While occasional use may sometimes be considered appropriate, it is not something to use without professional guidance during pregnancy. Your healthcare provider can recommend the safest option for managing constipation at this time.

What are the side effects of Cleen Ready to Use Enema?

Most people tolerate this product well, but side effects can include:

  • Rectal discomfort or irritation
  • Abdominal cramping
  • A strong urge to open the bowels
  • Electrolyte disturbances with repeated use

If you notice rectal bleeding, severe pain, or signs of an allergic reaction, stop use immediately and seek medical advice.

Can I use Cleen enema more than once a day?

No — you should not use more than one enema in a 24-hour period unless specifically directed by a doctor. Using it too frequently can cause electrolyte imbalances, particularly affecting sodium and phosphate levels in the blood. If constipation persists after a single dose, speak to your pharmacist or GP rather than repeating the dose.

What are alternatives to a phosphate enema for constipation?

There are several alternatives depending on the severity of your constipation. Oral laxatives such as lactulose, senna, or macrogol are commonly used first-line options. Glycerol suppositories offer another rectal option with a gentler action. You can explore our full constipation treatments range to compare products and find what suits you best.

Is Cleen enema the same as a Fleet enema?

Cleen Ready to Use Enema and Fleet enema are both sodium phosphate-based rectal solutions used for constipation relief and bowel preparation. They work via the same osmotic mechanism and are broadly comparable in terms of active ingredients and volume. Fleet is a US brand name, while Cleen is more commonly available in the UK market.

How long can you use Cleen Ready to Use Enema for?

This product is intended for short-term, occasional use only — not as a regular or long-term solution for constipation. If you find yourself needing to use an enema repeatedly, this suggests an underlying issue that needs proper medical assessment. Speak to your GP about investigating the root cause of your constipation.

Can Cleen enema interact with other medicines?

Yes, there are some interactions to be aware of. Diuretics (water tablets) and medicines that affect kidney function may increase the risk of electrolyte disturbances when used alongside a sodium phosphate enema. If you take lithium, the change in sodium levels could potentially affect lithium concentrations in the blood. Always tell your pharmacist about all medicines you are taking before using this product.

What is the best time to use Cleen Ready to Use Enema?

There is no single "best" time, but most people find it most practical to use the enema in the morning when they have time to remain near a toilet. If you are using it for bowel preparation before a procedure, your healthcare team will give you specific timing instructions. Make sure you have at least 30 minutes free after administration before leaving the house.

Are there any lifestyle changes that can help alongside using Cleen enema?

Yes — addressing the underlying causes of constipation is important for long-term bowel health. The NHS recommends increasing dietary fibre (fruits, vegetables, wholegrains), drinking plenty of fluids (at least 6–8 glasses of water daily), and taking regular physical activity. If you are also managing IBS-related symptoms, our IBS and cramps collection includes products that may support ongoing digestive comfort.

How Should You Use Cleen Ready to Use Enema?

Cleen Ready to Use Enema is for rectal use only — never take it by mouth. Before you begin, wash your hands thoroughly. The pre-filled bottle comes with a lubricated nozzle, so no additional preparation is needed.

Wash your hands again after use. The bottle is single-use only — never attempt to refill or reuse it.

What Is the Correct Dose of Cleen Ready to Use Enema?

The standard dose for adults and children aged 12 and over is one 133ml bottle per occasion. Do not use more than one bottle in a 24-hour period unless specifically instructed by a doctor or healthcare professional.

When Is the Best Time to Use Cleen Ready to Use Enema?

Most people find it most practical to use the enema in the morning, when they have time to remain near a toilet for at least 30 minutes after administration. Because the product typically works within 2 to 5 minutes, you should never use it immediately before leaving the house or travelling. If you are using it as part of bowel preparation for a medical procedure, follow the specific timing instructions given by your healthcare team — these may differ from general guidance.

How Long Can You Use Cleen Ready to Use Enema For?

This product is designed for short-term, occasional use only. It is not intended as a daily or long-term solution for constipation. If your constipation persists beyond a few days, or if you find yourself needing to use an enema regularly, you should speak to your GP. Ongoing constipation may have an underlying dietary, lifestyle, or medical cause that requires proper investigation and a longer-term management plan.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Cleen Ready to Use Enema?

Most people who use Cleen Ready to Use Enema experience only mild, short-lived side effects that resolve quickly after the bowel has been emptied. These are generally related to the local action of the solution in the rectum.

  • Rectal discomfort or a burning sensation during or after administration
  • Abdominal cramping or bloating
  • A strong and sudden urge to open the bowels
  • Mild nausea

What Are the Less Common Side Effects of Cleen Ready to Use Enema?

Less commonly, some people may experience side effects that go beyond local rectal discomfort. These are more likely to occur if the product is used more frequently than recommended or in people with pre-existing health conditions.

  • Electrolyte disturbances — symptoms may include muscle weakness, fatigue, irregular heartbeat, or unusual thirst
  • Rectal bleeding — this should always be investigated by a doctor
  • Dizziness or light-headedness
  • Dehydration, particularly in elderly patients or those with reduced kidney function

What Are the Serious Side Effects of Cleen Ready to Use Enema?

Serious side effects are rare when the product is used as directed, but they can occur — particularly in people with kidney disease, heart failure, or those who use the product repeatedly. Significant electrolyte imbalances involving sodium and phosphate can, in rare cases, lead to serious cardiovascular or neurological effects. Signs to watch for include chest pain, severe abdominal pain, confusion, or difficulty breathing. These require immediate medical attention.

What Should You Do If You Experience Side Effects?

For mild side effects such as cramping or rectal discomfort, no specific treatment is usually needed — they typically resolve once the bowel has been emptied. If you experience rectal bleeding, severe pain, or any symptoms that concern you, stop using the product and contact your GP or call NHS 111. In the event of a serious allergic reaction — characterised by swelling of the face, lips, or throat, difficulty breathing, or a widespread rash — call 999 immediately.

Can Cleen Ready to Use Enema Interact With Other Medicines?

Yes, there are some clinically relevant interactions to be aware of. Diuretics (water tablets) can increase the risk of electrolyte disturbances when used alongside sodium phosphate. Medicines that affect kidney function may reduce the body's ability to manage the phosphate load. If you take lithium, changes in sodium levels could potentially affect lithium concentrations in the blood, which requires monitoring. Always inform your pharmacist of all prescription and over-the-counter medicines you are taking before using this product.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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