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Cialis Together 10mg (Tadalafil) - 4 Tablets

Cialis Together 10mg (Tadalafil) - 4 Tablets

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  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Treats erectile dysfunction in adult men aged 18 and over
  • ✔️ Effects last up to 36 hours per single 10mg dose
  • ✔️ Works within 30 minutes of taking the tablet
  • ✔️ Can be taken with food — no fasting required
  • ✔️ UK-licensed OTC tadalafil, no GP appointment needed

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What Is Tadalafil 10mg and How Does It Treat Erectile Dysfunction?

 

Erectile dysfunction (ED) is more common than many people realise. In fact, the NHS estimates that around half of all men between 40 and 70 experience it to some degree. Tadalafil 10mg, sold under the brand name Cialis Together, is a clinically proven, UK-licensed over-the-counter treatment that helps men achieve and maintain an erection when they are sexually aroused. Each pack contains 4 tablets, making it a practical option for men who want a reliable, as-needed solution without a GP appointment. You can browse our full range of men's health products at Cured Pharmacy.

Cialis Together is available without a prescription in the UK for adult men aged 18 and over, following a short clinical assessment. It is the same active ingredient found in prescription-only Cialis, just available through a regulated pharmacy pathway for eligible patients.

 

How Does Cialis Together Work in the Body?

 

Tadalafil belongs to a class of medicines called phosphodiesterase type 5 (PDE5) inhibitors. Here is how it works, step by step:

  • Sexual stimulation triggers the release of nitric oxide in the erectile tissue of the penis.
  • Nitric oxide activates an enzyme that produces cyclic GMP (cGMP), which relaxes smooth muscle and widens blood vessels.
  • Tadalafil blocks the PDE5 enzyme, which would normally break down cGMP — so cGMP levels stay elevated.
  • This sustained increase in cGMP allows increased blood flow into the penis, supporting an erection.
  • The erection subsides naturally after sexual activity, as with a normal physiological response.

It is worth noting that tadalafil does not cause an erection on its own. Sexual stimulation is still required. The medicine simply makes it easier for the natural process to occur.

 

Who Is Suitable for Cialis Together 10mg Tablets?

 

Cialis Together is intended for adult men who experience difficulty getting or keeping an erection firm enough for satisfactory sexual activity. It is suitable if:

  • You are aged 18 or over.
  • You have been diagnosed with, or recognise symptoms of, erectile dysfunction.
  • You are not taking nitrate-based medicines (such as GTN spray or isosorbide mononitrate).
  • You do not have severe cardiovascular, hepatic, or renal impairment.

It is not suitable for women or anyone under 18. Men with certain heart conditions, low blood pressure, or those on specific interacting medicines should speak to a GP before use. The pharmacy questionnaire you complete at the point of purchase is designed to screen for these contraindications safely.

 

How Does Cialis Together Compare to Other ED Treatments?

 

Feature Cialis Together 10mg (Tadalafil) Sildenafil 50mg (Viagra Connect)
Active ingredient Tadalafil Sildenafil
Duration of action Up to 36 hours 4–6 hours
Time to onset 30–60 minutes 30–60 minutes
Food interaction Minimal — can be taken with food High-fat meals may delay onset
OTC availability in UK Yes Yes

 

How Should You Store Cialis Together and Is It Right for You?

 

Store Cialis Together tablets below 30°C in their original blister packaging, away from moisture and direct sunlight. Keep them out of the reach and sight of children. Do not use the tablets after the expiry date printed on the pack. If you are unsure whether tadalafil 10mg is appropriate for your circumstances — for example, if you have diabetes, high blood pressure, or take regular medicines — it is always sensible to speak to a pharmacist or GP first. You might also find it helpful to explore our condoms and sexual health range for complementary products.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Cialis Together 10mg (Tadalafil) - 4 Tablets specifications
Treatment category Erectile dysfunction
Mechanism of action PDE5 inhibitor — increases cGMP, relaxes smooth muscle, improves penile blood flow
Effective Up to 36 hours per dose
Suitable for Adult men aged 18 and over
Active ingredient Tadalafil 10mg
Pack sizes 4 tablets
Strengths 10mg
UK classification Pharmacy (P) medicine
Drug class PDE5 inhibitor
Preparation Film-coated tablet
Route of administration Oral

Specifications of Cialis Together 10mg (Tadalafil) - 4 Tablets

 

What Is Cialis Together and What Is It Used For?

 

Cialis Together contains tadalafil 10mg as its active ingredient. It is used to treat erectile dysfunction in adult men — that is, difficulty achieving or maintaining an erection sufficient for satisfactory sexual intercourse. It is a Pharmacy (P) medicine available over the counter in the UK following a pharmacist assessment. It does not protect against sexually transmitted infections, and it is not a contraceptive.

 

What Do You Need to Know Before Using Cialis Together?

 

Do not take Cialis Together if any of the following apply to you:

  • You are taking nitrates in any form (e.g. GTN spray, isosorbide mononitrate, isosorbide dinitrate) — the combination can cause a dangerous drop in blood pressure.
  • You have severe heart disease or have had a heart attack or stroke in the past 90 days.
  • You have severe liver impairment or are on dialysis for kidney disease.
  • You have low blood pressure (hypotension) — below 90/50 mmHg.
  • You have ever experienced loss of vision due to non-arteritic anterior ischaemic optic neuropathy (NAION).
  • You are under 18 years of age.
  • You are a woman.

Be cautious and speak to your GP or pharmacist if you have any of the following conditions or are taking these medicines:

  • Alpha-blockers (e.g. tamsulosin, doxazosin) — may cause blood pressure to drop.
  • Antifungals such as ketoconazole or itraconazole — these can increase tadalafil levels in the blood.
  • HIV protease inhibitors (e.g. ritonavir, saquinavir).
  • Rifampicin, phenytoin, carbamazepine, or phenobarbital — these may reduce tadalafil's effectiveness.
  • Other PDE5 inhibitors or treatments for pulmonary arterial hypertension containing tadalafil.

 

How Should You Use Cialis Together Correctly?

 

  1. Read the patient information leaflet inside the pack before taking your first tablet.
  2. Swallow one 10mg tablet whole with a glass of water.
  3. Take it at least 30 minutes before planned sexual activity.
  4. Do not take more than one tablet in any 24-hour period.
  5. Sexual stimulation is still required for the medicine to work.
  6. Do not crush or split the tablet.
Indication Age Group Dose Frequency
Erectile dysfunction (as needed) Adult men 18+ 10mg Once per 24 hours, as needed
Not applicable Under 18 / Women Not recommended Not recommended

If 10mg does not produce a satisfactory response, speak to your GP — a higher dose (20mg) or a different treatment may be more appropriate on prescription. You can also explore our personal lubricants range for additional sexual health support.

 

What Are the Possible Side Effects of Cialis Together?

 

Like all medicines, tadalafil can cause side effects, although not everyone gets them. Most are mild and short-lived.

Common side effects (may affect up to 1 in 10 people):

  • Headache
  • Indigestion or heartburn
  • Back pain
  • Muscle aches
  • Flushing (redness or warmth in the face, neck, or chest)
  • Nasal congestion or runny nose

Less common side effects (may affect up to 1 in 100 people):

  • Dizziness
  • Blurred vision
  • Stomach pain
  • Increased heart rate (palpitations)
  • Swelling of the eyelids
  • Eye pain or redness

Seek immediate medical attention if you experience a sudden loss of vision, a prolonged erection lasting more than 4 hours (priapism), or signs of a severe allergic reaction such as swelling of the face, lips, or throat. These are rare but serious.

 

How Should You Store Cialis Together Safely?

 

  • Store below 30°C.
  • Keep in the original blister packaging to protect from moisture.
  • Do not store in the bathroom or near a sink.
  • Keep out of the sight and reach of children.
  • Do not use after the expiry date printed on the pack.
  • Do not dispose of medicines via wastewater or household waste — return unused tablets to your pharmacy.

If you have any concerns about storage or suitability, our pharmacists at Cured Pharmacy are available to help. You may also find our vitamins and supplements range useful for supporting your general health alongside treatment.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Cialis Together 10mg online in the UK?

You can buy Cialis Together 10mg (Tadalafil) directly from Cured Pharmacy, a GPhC-registered online pharmacy. You will need to complete a short clinical questionnaire to confirm you are suitable before your order is dispensed. Browse our full men's health range for more options.

How does tadalafil 10mg work in the body?

Tadalafil inhibits the PDE5 enzyme, which normally breaks down cGMP in penile tissue. By blocking PDE5, tadalafil allows cGMP to accumulate, relaxing smooth muscle and increasing blood flow to the penis during sexual stimulation. An erection will not occur without arousal — the medicine simply supports the natural process.

How long does Cialis Together 10mg last?

Tadalafil has a half-life of approximately 17.5 hours, and its effects can last up to 36 hours after a single dose. This extended window is one of the key differences between tadalafil and shorter-acting ED treatments like sildenafil. It gives you more flexibility around timing without needing to plan precisely.

How do I use Cialis Together step by step?

Swallow one 10mg tablet whole with water at least 30 minutes before sexual activity. Do not take more than one tablet in any 24-hour period, and do not crush or chew the tablet. Sexual stimulation is still needed for the medicine to work effectively.

What is the best time to take Cialis Together 10mg?

Take Cialis Together at least 30 minutes before you plan to have sex, though because it lasts up to 36 hours, the exact timing is more flexible than with some other ED treatments. Unlike sildenafil, tadalafil is not significantly affected by food, so you can take it with or without a meal. Many men find this flexibility makes it easier to fit into their routine.

What are the common side effects of tadalafil 10mg and how do I manage them?

The most common side effects include headache, flushing, indigestion, back pain, and nasal congestion. These are usually mild and resolve within a few hours without any treatment needed. Staying well hydrated and avoiding excessive alcohol can help reduce their likelihood.

Who is eligible to buy Cialis Together 10mg over the counter?

Cialis Together is available to adult men aged 18 and over who experience erectile dysfunction and do not have contraindicated conditions such as severe heart disease or current nitrate use. You will need to complete a pharmacy questionnaire to confirm eligibility before purchase. It is not suitable for women or anyone under 18.

What happens if I miss a dose of Cialis Together?

Cialis Together is taken on an as-needed basis rather than as a daily scheduled dose, so there is no concept of a "missed dose" in the traditional sense. Simply take one tablet at least 30 minutes before sexual activity when needed. Never take two tablets to make up for a missed one.

Can I take Cialis Together 10mg with alcohol?

Moderate alcohol consumption is unlikely to cause problems, but drinking heavily while taking tadalafil can increase the risk of side effects such as dizziness, flushing, and low blood pressure. The NHS advises caution with alcohol when taking PDE5 inhibitors. It is sensible to keep alcohol intake low on the day you take the tablet.

Who should not take Cialis Together 10mg?

You should not take Cialis Together if you use nitrate medicines for chest pain, have severe cardiovascular disease, have had a recent stroke or heart attack, or have severe liver or kidney impairment. Men with hereditary eye conditions such as retinitis pigmentosa should also avoid it. Always answer the pharmacy questionnaire honestly to ensure your safety.

How does Cialis Together compare to Viagra Connect (sildenafil)?

Both are PDE5 inhibitors available over the counter in the UK, but tadalafil lasts up to 36 hours compared to sildenafil's 4–6 hours. Tadalafil is also less affected by food, whereas a high-fat meal can delay sildenafil's onset. The choice between them often comes down to personal preference and lifestyle.

What are the alternatives to Cialis Together 10mg?

Alternatives include Viagra Connect (sildenafil 50mg), which is also available OTC, or prescription-only options such as vardenafil (Levitra) and avanafil (Spedra). Lifestyle changes — including weight management, reducing alcohol, stopping smoking, and managing stress — can also improve erectile function. You can explore our sexual health range for complementary products.

How long can you keep taking Cialis Together 10mg?

Cialis Together is intended for as-needed use and can be used over the longer term, but if you find you are relying on it frequently, it is worth speaking to your GP to explore any underlying causes of your erectile dysfunction. Conditions such as diabetes, high blood pressure, and cardiovascular disease can all contribute to ED. Addressing the root cause is always worthwhile alongside any medication.

Does tadalafil 10mg work the first time you take it?

Many men find tadalafil effective from the first dose, though some may need to try it two or three times before achieving the best results — particularly if anxiety is a contributing factor. If 10mg does not produce a satisfactory response after several attempts, speak to your GP about whether a higher dose or alternative treatment is appropriate. Performance anxiety can sometimes reduce effectiveness initially.

What are the latest findings on tadalafil for erectile dysfunction?

Tadalafil remains one of the most widely studied and clinically established treatments for erectile dysfunction, with a well-documented safety and efficacy profile built over more than two decades of use. Research continues to explore its role in other conditions, including benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension. For ED specifically, it is recognised by the NHS as an effective first-line treatment option.

How Should You Use Cialis Together 10mg?

Cialis Together 10mg tablets are taken orally, swallowed whole with a glass of water. Unlike some other erectile dysfunction treatments, tadalafil can be taken with or without food, which makes it more convenient for everyday use. Follow these steps each time you take a tablet:

If you have any questions about how to take this medicine, speak to your pharmacist before use.

What Is the Correct Dose of Cialis Together 10mg?

The standard dose for Cialis Together is one 10mg tablet taken as needed, no more than once in any 24-hour period. If you find the 10mg dose is not effective after several attempts, do not take an extra tablet — instead, speak to your GP who may consider prescribing a higher dose on prescription. The table below summarises dosing guidance:

Do not exceed one tablet in 24 hours under any circumstances. Taking more than the recommended dose increases the risk of side effects without improving effectiveness.

When Is the Best Time to Use Cialis Together 10mg?

Take Cialis Together at least 30 minutes before planned sexual activity. Because tadalafil remains active in the body for up to 36 hours, you have a wide window of opportunity — you do not need to time it as precisely as shorter-acting treatments. This flexibility means many men find it easier to incorporate into their lives without the pressure of strict timing. Avoid taking it at the same time as a large amount of alcohol, as this can increase the risk of side effects such as dizziness.

How Long Can You Use Cialis Together 10mg For?

Cialis Together is designed for as-needed use and can be used over an extended period, provided you remain suitable for the medicine. However, if you find yourself needing it very frequently, it is worth discussing this with your GP to rule out any underlying health conditions contributing to your erectile dysfunction. Conditions such as cardiovascular disease, diabetes, and hormonal imbalances can all affect erectile function and may benefit from specific treatment. Regular review with a healthcare professional is recommended for ongoing use.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Cialis Together 10mg?

Most men who take tadalafil tolerate it well, but like all medicines, it can cause side effects in some people. Common side effects affect up to 1 in 10 users and are generally mild and short-lived. They tend to ease on their own within a few hours.

  • Headache
  • Flushing (warmth or redness in the face, neck, or chest)
  • Indigestion or heartburn
  • Back pain
  • Muscle aches
  • Nasal congestion or runny nose

What Are the Less Common Side Effects of Cialis Together?

Less common side effects affect fewer than 1 in 100 people. If you notice any of the following, they are not usually dangerous but you should mention them to your pharmacist or GP if they persist or bother you.

  • Dizziness or light-headedness
  • Blurred vision or changes in colour perception
  • Stomach pain or nausea
  • Increased heart rate (palpitations)
  • Swelling of the eyelids
  • Eye redness or discomfort
  • Rash or skin reactions

What Are the Serious Side Effects of Cialis Together 10mg?

Serious side effects are rare but require immediate medical attention. Stop taking tadalafil and seek emergency help if you experience any of the following:

  • Sudden loss of vision in one or both eyes — this may indicate non-arteritic anterior ischaemic optic neuropathy (NAION).
  • Sudden loss of hearing, sometimes with ringing in the ears or dizziness.
  • A prolonged erection lasting more than 4 hours (priapism) — this is a medical emergency and can cause permanent damage if untreated.
  • Signs of a severe allergic reaction: swelling of the face, lips, tongue, or throat; difficulty breathing; or a widespread skin rash.
  • Chest pain, particularly during or after sexual activity.

What Should You Do If You Experience Side Effects of Cialis Together?

For mild side effects such as headache or flushing, no specific treatment is usually needed — staying hydrated and resting is often sufficient. If side effects are troublesome or do not resolve, stop taking the tablets and speak to your pharmacist or GP. You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. Never take an additional tablet to try to counteract a side effect.

Can Cialis Together Interact With Other Medicines?

Yes — tadalafil has several clinically significant interactions. The most important is with nitrate medicines (such as GTN spray or isosorbide mononitrate), which are used for chest pain. Taking tadalafil with nitrates can cause a severe and potentially life-threatening drop in blood pressure. Alpha-blockers used for prostate problems or high blood pressure (such as tamsulosin or doxazosin) can also lower blood pressure when combined with tadalafil. Antifungal medicines like ketoconazole and HIV protease inhibitors such as ritonavir can increase tadalafil blood levels, raising the risk of side effects. Always tell your pharmacist about every medicine you take, including herbal remedies and supplements, before starting Cialis Together.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Frequently Asked Question

Cialis Together, created for adult men with erectile dysfunction (ED) — the inability to obtain ormaintaina rigid penis for sex.No matter the cause of yourEDwhether it bestressor lifestyle,Cialis Together helps you perform naturally again, givingyou thatreassurance and control when it matters most.

One 10mg tablet can last for up to 36 hours — that’s why it’s often called the “weekend pill.”

No, Cialis Together is designed for “as needed” use — only one tablet in 24 hours. If you prefer a daily option, your pharmacist might recommend Tadalafil Daily (2.5mg or 5mg) instead.

Like all medications, Cialis Together (Tadalafil) can cause some side effects, although not everyone gets them. Most of these are mild and short-lived, especially when your body is still adjusting to the treatment.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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What exactly is Cialis Together?

Cialis Together, created for adult men with erectile dysfunction (ED) — the inability to obtain ormaintaina rigid penis for sex.No matter the cause of yourEDwhether it bestressor lifestyle,Cialis Together helps you perform naturally again, givingyou thatreassurance and control when it matters most.

How long does Cialis Together last?

One 10mg tablet can last for up to 36 hours — that’s why it’s often called the “weekend pill.”

Can I take Cialis Together every day?

No, Cialis Together is designed for “as needed” use — only one tablet in 24 hours. If you prefer a daily option, your pharmacist might recommend Tadalafil Daily (2.5mg or 5mg) instead.

Is Cialis Together safe for everyone?

Like all medications, Cialis Together (Tadalafil) can cause some side effects, although not everyone gets them. Most of these are mild and short-lived, especially when your body is still adjusting to the treatment.