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Cetirizine Hydrochloride 5mg/5ml Oral Solution 200ml (Brand May Vary)

Cetirizine Hydrochloride 5mg/5ml Oral Solution 200ml (Brand May Vary)

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  • ✔️ Relieves hay fever, hives, and allergic rhinitis symptoms effectively
  • ✔️ Liquid format ideal for children aged two years and over
  • ✔️ Starts working within approximately one hour of each dose
  • ✔️ Each 5ml contains 5mg cetirizine hydrochloride for accurate dosing
  • ✔️ 200ml bottle provides extended supply throughout allergy season

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What Is Cetirizine Oral Solution and How Does It Help Allergies?

 

Allergies can make everyday life genuinely miserable — the constant sneezing, the itchy eyes, the runny nose that just won't quit. If you or your child struggle to swallow tablets, a liquid antihistamine can make all the difference. Cetirizine oral solution 5mg/5ml is a second-generation antihistamine available over the counter, offering effective relief from hay fever, allergic rhinitis, urticaria (hives), and other allergic conditions. Each 5ml of solution contains 5mg of cetirizine hydrochloride, making it straightforward to measure an accurate dose for both adults and children. You can browse our full range of allergy and hay fever treatments if you'd like to explore other options alongside this product.

This 200ml bottle provides a generous supply, particularly useful during peak pollen season or for households managing ongoing allergic conditions. The liquid format is especially practical for younger children aged 2 and over, or for anyone who finds tablets difficult to take. Brand may vary, but the active ingredient and strength remain consistent.

 

How Does Cetirizine Hydrochloride Work to Relieve Allergy Symptoms?

 

Cetirizine hydrochloride works by selectively blocking histamine H1 receptors throughout the body. When you encounter an allergen — pollen, pet dander, dust mites — your immune system releases histamine, a chemical that triggers the familiar cascade of allergy symptoms. By blocking the receptor sites where histamine would normally bind, cetirizine interrupts that process before symptoms can fully develop.

  • Histamine is released in response to an allergen entering the body
  • Cetirizine selectively binds to peripheral H1 receptors, blocking histamine attachment
  • Inflammatory signals are reduced, decreasing sneezing, itching, and nasal congestion
  • As a second-generation antihistamine, it has lower penetration of the blood-brain barrier compared to older antihistamines, meaning it is less likely to cause significant sedation

The effect typically begins within one hour of taking a dose and can last up to 24 hours, which is why once-daily dosing is often sufficient for adults and older children.

 

Who Is Cetirizine Oral Solution Suitable For?

 

This liquid formulation is particularly well suited to people who need an antihistamine but prefer — or require — a non-tablet format. It is licensed for use in children from 2 years of age, making it one of the more versatile antihistamine options available without a prescription.

  • Adults and adolescents aged 12 and over with hay fever or allergic rhinitis
  • Children aged 2 to 11 years requiring a measured liquid dose
  • People with chronic urticaria (persistent hives) needing ongoing symptom management
  • Anyone who finds swallowing tablets difficult, including older adults

It is not suitable for children under 2 years, people with severe renal impairment, or those with a known hypersensitivity to cetirizine or hydroxyzine. Always check with your pharmacist if you are unsure whether this product is right for you.

 

How Does Cetirizine Oral Solution Compare to Cetirizine Tablets?

 

Feature Cetirizine Oral Solution 5mg/5ml Cetirizine Tablets 10mg
Suitable age From 2 years Usually 6 years and over (tablet form)
Dose flexibility Easily adjustable by volume Fixed 10mg dose per tablet
Ease of administration Ideal for children and those with swallowing difficulties Convenient for adults who prefer tablets
Pack size 200ml bottle Typically 7–30 tablets per pack

 

How Should You Store Cetirizine Oral Solution and Is It Clinically Suitable for Long-Term Use?

 

Store this medicine below 25°C, away from direct sunlight and out of the reach of children. Do not use after the expiry date printed on the label. Once opened, check the product leaflet for any specific in-use storage guidance, as this can vary by brand.

Cetirizine oral solution can be used on a longer-term basis for conditions such as chronic urticaria, but it is worth reviewing ongoing use with your GP or pharmacist periodically. If you are also managing symptoms like itchy or watery eyes alongside hay fever, you might find our eye care range a helpful complement to antihistamine treatment. As with all medicines, use the lowest effective dose for the shortest time necessary unless otherwise directed by a healthcare professional.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Cetirizine Hydrochloride 5mg/5ml Oral Solution 200ml specifications
Treatment category Allergy & Hay Fever
Active ingredient Cetirizine hydrochloride 5mg per 5ml
Mechanism of action Selective peripheral H1 histamine receptor antagonist
Drug class Second-generation antihistamine
Preparation Oral solution
Route of administration Oral
Strengths 5mg/5ml
Pack sizes 200ml
Suitable for Adults and children aged 2 years and over
UK classification P (Pharmacy medicine)
Effective for Hay fever, allergic rhinitis, urticaria, allergic conjunctivitis

Specifications of Cetirizine Hydrochloride 5mg/5ml Oral Solution 200ml

 

What Is Cetirizine Hydrochloride Oral Solution and What Is It Used For?

 

Cetirizine hydrochloride 5mg/5ml oral solution is an antihistamine medicine used to relieve the symptoms of allergic conditions. It belongs to a group of medicines called second-generation antihistamines, which are less sedating than older antihistamines. It is used to treat:

  • Hay fever (seasonal allergic rhinitis) — sneezing, runny nose, itchy and watery eyes
  • Perennial allergic rhinitis — year-round allergy symptoms triggered by dust mites, pet dander, or mould
  • Urticaria (hives) — itchy, raised welts on the skin caused by an allergic reaction
  • Allergic conjunctivitis — itchy, red, or watery eyes associated with allergies

The liquid format makes it particularly suitable for children aged 2 and over, as well as adults who prefer not to take tablets. It is available over the counter from UK pharmacies without a prescription.

 

What Do You Need to Know Before Using Cetirizine Oral Solution?

 

Before taking this medicine, read the following carefully. Do not take cetirizine oral solution if any of the following apply to you:

  • You are allergic to cetirizine hydrochloride, hydroxyzine, or any other ingredient in the solution
  • You have severe kidney (renal) impairment
  • Your child is under 2 years of age
  • You have been told you have a rare hereditary problem with fructose intolerance (if the solution contains sorbitol — check the product leaflet)

Take special care and speak to your pharmacist or GP before using this medicine if you have:

  • Kidney problems (a dose reduction may be needed)
  • Epilepsy or a history of seizures
  • Difficulty passing urine (urinary retention)
  • A condition that predisposes you to heart rhythm problems (QT prolongation)

Drug interactions — tell your pharmacist if you are taking:

  • Alcohol or sedative medicines — increased risk of drowsiness
  • Ritonavir (used to treat HIV) — may increase cetirizine blood levels
  • Other antihistamines — avoid combining without medical advice
  • CNS depressants (e.g. sleeping tablets, anxiolytics) — additive sedative effect possible

 

How Should You Use Cetirizine Hydrochloride Oral Solution Correctly?

 

Always use this medicine exactly as described in the patient information leaflet or as directed by your pharmacist. Use the measuring device provided — do not estimate doses using a household spoon.

  1. Shake the bottle gently if instructed on the label
  2. Use the oral syringe or measuring spoon provided to draw up the correct dose
  3. Administer the solution directly into the mouth or mix with a small amount of water if preferred
  4. Take with or without food — food does not significantly affect absorption
  5. Replace the cap securely after each use
Age Group Dose Frequency Maximum Daily Dose
Adults & children 12+ 10ml (10mg) Once daily 10mg
Children 6–11 years 5ml (5mg) Twice daily 10mg
Children 2–5 years 2.5ml (2.5mg) Twice daily 5mg
Children under 2 years Not recommended without medical supervision

If you have kidney problems, your pharmacist or doctor may recommend a lower dose or less frequent dosing. For children and families managing multiple allergy-related conditions, our baby and toddler health range includes additional products that may be helpful alongside antihistamine treatment.

 

What Are the Possible Side Effects of Cetirizine Oral Solution?

 

Like all medicines, cetirizine can cause side effects, although not everyone gets them. Most side effects are mild and resolve on their own.

Common side effects (may affect up to 1 in 10 people):

  • Drowsiness or fatigue
  • Dry mouth
  • Headache
  • Dizziness
  • Pharyngitis (sore throat)

Less common side effects (may affect up to 1 in 100 people):

  • Abdominal pain or nausea
  • Agitation or restlessness (more common in children)
  • Paraesthesia (tingling or numbness)
  • Urinary retention
  • Pruritus (itching) or skin rash

Rarely, cetirizine can cause a serious allergic reaction (anaphylaxis). Stop taking the medicine and seek emergency medical help immediately if you develop swelling of the face, lips, tongue or throat, difficulty breathing, or a severe skin reaction.

 

How Should You Store Cetirizine Oral Solution Safely?

 

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Keep the bottle tightly closed when not in use
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the label or packaging
  • Do not dispose of medicines via wastewater or household waste — return unused medicine to your pharmacy

If you are managing a range of allergy-related symptoms beyond hay fever — such as skin reactions or hives — you may also find our skin care range useful for complementary topical relief.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy cetirizine oral solution online in the UK?

You can buy cetirizine hydrochloride 5mg/5ml oral solution 200ml directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available over the counter without a prescription for eligible patients aged 2 and over. Simply add it to your basket and it will be dispatched from our registered pharmacy. You can also browse our wider allergy and hay fever collection for complementary products.

How does cetirizine oral solution work in the body?

Cetirizine is a second-generation antihistamine that works by selectively blocking peripheral H1 histamine receptors. When your body encounters an allergen, it releases histamine — a chemical that causes sneezing, itching, and a runny nose. By blocking the receptor sites where histamine would normally bind, cetirizine prevents these symptoms from developing. It starts working within approximately one hour and the effect can last up to 24 hours.

How do I measure and give cetirizine oral solution step by step?

Use the oral syringe or measuring spoon provided with the bottle — never a household teaspoon, as this is inaccurate. Draw up the correct volume for the patient's age group, administer it directly into the mouth, and replace the cap securely after use. The solution can be taken with or without food, and food does not significantly affect how well it is absorbed.

What is the correct dose of cetirizine 5mg/5ml oral solution for children?

For children aged 2 to 5 years, the usual dose is 2.5ml (2.5mg) twice daily, giving a maximum of 5mg per day. Children aged 6 to 11 years can take 5ml (5mg) twice daily, up to a maximum of 10mg per day. Adults and children aged 12 and over take 10ml (10mg) once daily. Always follow the dosage instructions on the product label or as directed by your pharmacist.

What is the best time of day to take cetirizine oral solution?

For adults and children aged 12 and over taking a once-daily dose, cetirizine can be taken at any time of day — morning or evening. Some people prefer to take it in the evening as it can cause mild drowsiness in some individuals, which may actually aid sleep during hay fever season. For twice-daily dosing in younger children, spacing doses approximately 12 hours apart is generally recommended.

What are the side effects of cetirizine oral solution and how do I manage them?

The most common side effects include drowsiness, dry mouth, headache, and fatigue. If drowsiness is a problem, try taking the dose in the evening rather than the morning. Staying well hydrated can help with dry mouth. If you or your child experience agitation, restlessness, or any unusual symptoms, stop the medicine and speak to your pharmacist or GP promptly.

Can I give cetirizine liquid to my toddler or baby?

Cetirizine oral solution is licensed for use in children from 2 years of age. It should not be given to children under 2 years without direct medical supervision and a prescription from a GP. If your child is under 2 and experiencing allergy symptoms, please consult your GP before using any antihistamine. Our baby and toddler range includes other age-appropriate products that may help.

Who is not eligible to use cetirizine oral solution?

Cetirizine oral solution is not suitable for children under 2 years, people with severe kidney (renal) impairment, or anyone with a known allergy to cetirizine hydrochloride or hydroxyzine. People with epilepsy, urinary retention, or certain heart conditions should speak to their GP or pharmacist before use. Pregnant or breastfeeding women should also seek medical advice before taking this medicine.

What happens if I miss a dose of cetirizine oral solution?

If you miss a dose, take it as soon as you remember — unless it is nearly time for your next dose, in which case skip the missed dose entirely. Never take a double dose to make up for a missed one. Missing an occasional dose is unlikely to cause any harm, but try to take it at the same time each day to maintain consistent symptom control.

Can I take cetirizine oral solution with other medicines?

Cetirizine can interact with alcohol, sedatives, sleeping tablets, and other CNS depressants, increasing the risk of drowsiness. Ritonavir (used in HIV treatment) may increase cetirizine blood levels. You should not combine cetirizine with other antihistamines without medical advice. Always tell your pharmacist about every medicine, supplement, or herbal remedy you are taking before starting cetirizine.

What are the alternatives to cetirizine oral solution for hay fever?

Other second-generation antihistamines available in the UK include loratadine and fexofenadine, both of which are considered non-sedating. Chlorphenamine is an older, first-generation antihistamine that is more sedating but still widely used. Nasal corticosteroid sprays such as beclometasone are also effective for allergic rhinitis. Your pharmacist can help you choose the most appropriate option based on your symptoms and medical history.

How long can you take cetirizine oral solution for?

For seasonal hay fever, cetirizine is typically taken throughout the pollen season, which in the UK usually runs from late March to September. For chronic urticaria or perennial allergic rhinitis, longer-term use may be appropriate under the guidance of a GP or allergy specialist. It is good practice to review ongoing antihistamine use with your healthcare provider at least once a year.

Is cetirizine oral solution safe to take every day?

Yes, cetirizine is considered safe for daily use when taken at the recommended dose for the appropriate age group. It does not cause tolerance or dependency with regular use. However, if you find you need to take it every day for extended periods, it is worth discussing this with your GP to ensure the underlying allergic condition is being managed appropriately.

Can cetirizine oral solution be taken during pregnancy or breastfeeding?

Cetirizine is not recommended during pregnancy unless clearly necessary and advised by a doctor, as there is limited data on its safety in pregnant women. It passes into breast milk in small amounts, so breastfeeding women should seek medical advice before using it. Your GP can advise on the safest antihistamine option for your individual circumstances during pregnancy or while breastfeeding.

What are the latest findings on cetirizine use in children with allergies?

Cetirizine remains one of the most widely studied antihistamines in paediatric allergy management and continues to be recommended by UK clinical guidelines for children aged 2 and over. Current NHS guidance supports its use for allergic rhinitis and urticaria in children, with a well-established safety profile at licensed doses. Research continues to confirm that second-generation antihistamines like cetirizine offer effective symptom relief with a lower sedation risk compared to first-generation alternatives.

How Should You Use Cetirizine Hydrochloride 5mg/5ml Oral Solution?

Always use this medicine exactly as described in the patient information leaflet supplied with the product, or as directed by your pharmacist. The liquid format makes it easy to measure an accurate dose for both adults and children. Never estimate the dose using a household teaspoon — always use the oral syringe or measuring spoon provided.

Follow these steps each time you take a dose:

What Is the Correct Dose of Cetirizine Oral Solution?

The dose depends on the patient's age. Do not exceed the maximum daily dose for any age group. If you are unsure which dose applies, ask your pharmacist before administering.

Patients with mild to moderate kidney impairment may require a reduced dose or less frequent dosing — speak to your GP or pharmacist for personalised guidance.

When Is the Best Time to Use Cetirizine Oral Solution?

For adults and children aged 12 and over taking a once-daily dose, cetirizine can be taken at any time of day — morning or evening. If you find it causes mild drowsiness, taking it in the evening may be more convenient and could even help you sleep more comfortably during hay fever season. Consistency matters — try to take it at the same time each day to maintain steady symptom control.

For children on a twice-daily regimen, spacing the doses approximately 12 hours apart — for example, morning and evening — helps maintain consistent antihistamine levels throughout the day and night.

How Long Can You Use Cetirizine Oral Solution For?

For seasonal hay fever, use cetirizine throughout the relevant pollen season, which in the UK typically runs from late March through to September, depending on which pollens trigger your symptoms. You can stop taking it once the season ends and your symptoms resolve.

For chronic conditions such as perennial allergic rhinitis or chronic urticaria, longer-term daily use may be appropriate. In these cases, it is advisable to review your treatment with your GP or pharmacist at least once a year to ensure it remains the most suitable option for you.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Cetirizine Oral Solution?

Most people tolerate cetirizine oral solution well, but like all medicines it can cause side effects in some people. Common side effects affect up to 1 in 10 people and are generally mild. If any of these bother you or do not resolve, speak to your pharmacist.

  • Drowsiness or sleepiness
  • Dry mouth
  • Headache
  • Fatigue or tiredness
  • Pharyngitis (sore throat)
  • Dizziness

What Are the Less Common Side Effects of Cetirizine Oral Solution?

Less common side effects affect up to 1 in 100 people. These are less frequently reported but worth being aware of, particularly in children, who may be more susceptible to some of these effects.

  • Agitation or restlessness (particularly in young children)
  • Abdominal pain or nausea
  • Paraesthesia (tingling or pins and needles)
  • Urinary retention (difficulty passing urine)
  • Pruritus (itching) or skin rash
  • Palpitations
  • Oedema (swelling)

What Are the Serious Side Effects of Cetirizine Oral Solution?

Serious side effects are rare but require immediate medical attention. Stop taking cetirizine and call 999 or go to your nearest A&E if you experience any of the following signs of a serious allergic reaction (anaphylaxis):

  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Severe skin reaction — blistering, peeling, or widespread rash
  • Sudden drop in blood pressure causing dizziness or collapse

Very rarely, cetirizine has been associated with liver problems. Seek medical advice promptly if you develop yellowing of the skin or eyes (jaundice), dark urine, or persistent upper abdominal pain.

What Should You Do If You Experience Side Effects of Cetirizine?

For mild side effects such as drowsiness, try switching to an evening dose rather than a morning one. Staying well hydrated can help manage dry mouth. If side effects are persistent, troublesome, or worsening, stop taking the medicine and speak to your pharmacist or GP. You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Never stop a prescribed medicine without speaking to your doctor first. For over-the-counter use, if you are concerned about any side effect, your pharmacist is your first point of contact.

Can Cetirizine Oral Solution Interact With Other Medicines?

Yes. Cetirizine can interact with certain medicines and substances, potentially increasing side effects or altering how the medicine works. The most clinically significant interactions include:

  • Alcohol — increases the risk of drowsiness and impaired concentration; avoid alcohol while taking cetirizine
  • Sedatives and sleeping tablets — additive CNS depressant effect; use with caution
  • Ritonavir (HIV medicine) — may increase cetirizine plasma levels, raising the risk of side effects
  • Other antihistamines — do not combine without medical advice

Always inform your pharmacist or GP of all medicines, supplements, and herbal remedies you are taking before starting cetirizine oral solution.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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