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Care Maximum Strength 400mg Tablets 48

Care Maximum Strength 400mg Tablets 48

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  • ✔️ Relieves headaches, back pain, and period pain effectively
  • ✔️ Maximum non-prescription ibuprofen strength at 400mg per tablet
  • ✔️ Anti-inflammatory action targets the root cause of pain
  • ✔️ Suitable for adults and adolescents aged 12 and over
  • ✔️ 48-tablet pack provides a reliable supply for ongoing relief

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What Are Ibuprofen 400mg Tablets Used For?

 

Care Maximum Strength 400mg Tablets contain ibuprofen 400mg tablets as the active ingredient — one of the most widely used over-the-counter pain relievers available in the UK. Each pack contains 48 tablets, giving you a reliable supply for managing a range of everyday painful conditions. Whether you're dealing with a persistent headache, muscular aches after exercise, or the discomfort of a dental procedure, these tablets are formulated to provide effective relief at the maximum non-prescription strength. You can explore our full pain relief collection if you're looking for additional options to suit your needs.

Ibuprofen belongs to a class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It's been used clinically for decades and is well-established in both primary care and self-care settings across the UK. The NHS recognises ibuprofen as a first-line option for mild to moderate pain in adults and adolescents aged 12 and over.

 

How Do Care Maximum Strength 400mg Tablets Work?

 

Ibuprofen works by inhibiting enzymes called cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). These enzymes are responsible for producing prostaglandins — chemical messengers that trigger pain, swelling, and fever in the body. By reducing prostaglandin production, ibuprofen tackles the root cause of discomfort rather than simply masking it.

  • Blocks COX-1 and COX-2 enzymes at the site of inflammation
  • Reduces prostaglandin synthesis, lowering pain signals sent to the brain
  • Decreases local swelling and tissue inflammation
  • Lowers elevated body temperature by acting on the hypothalamus

The anti-inflammatory action makes it particularly useful for conditions where swelling is a contributing factor to pain — such as sprains, strains, and arthritis flare-ups.

 

Who Is Care Maximum Strength 400mg Suitable For?

 

These tablets are suitable for adults and adolescents aged 12 years and over who need relief from mild to moderate pain or fever. They're a practical choice for people who find lower-strength ibuprofen (200mg) insufficient for their symptoms.

  • Adults experiencing headaches, migraines, or dental pain
  • People with period pain (dysmenorrhoea)
  • Those with muscular aches, back pain, or rheumatic pain
  • Individuals with mild fever who need an antipyretic alongside pain relief

They are not suitable for children under 12, people with certain gastrointestinal conditions, or those in the third trimester of pregnancy. Always check the full list of contraindications before use.

 

How Do Care 400mg Tablets Compare to Lower-Strength Ibuprofen?

 

Feature Care Maximum Strength 400mg Standard Ibuprofen 200mg
Strength per tablet 400mg 200mg
Tablets per dose (adult) 1 tablet 1–2 tablets
Maximum daily dose 1,200mg (3 tablets) 1,200mg (6 tablets)
Suitable for age 12+ Yes Yes (200mg only)
Pack size (this product) 48 tablets Varies

 

How Should You Store Care Maximum Strength 400mg Tablets?

 

Store these tablets below 25°C in a dry place, away from direct sunlight and moisture. Keep them in their original packaging and out of the reach and sight of children at all times. Do not use the tablets after the expiry date printed on the pack — if in doubt, return them to your local pharmacy for safe disposal.

If you're managing multiple health conditions alongside pain, it's worth knowing that Cured Pharmacy also stocks a range of vitamins and supplements that may support your overall wellbeing. This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Care Maximum Strength 400mg Tablets 48 specifications
Treatment category Pain Relief / Anti-inflammatory / Antipyretic
Active ingredient Ibuprofen 400mg
Mechanism of action COX-1 and COX-2 enzyme inhibitor (NSAID)
Suitable for Adults and adolescents aged 12 and over
Pack size 48 tablets
Strength 400mg per tablet
UK classification Pharmacy (P) medicine
Drug class Non-steroidal anti-inflammatory drug (NSAID)
Preparation Film-coated tablet
Route of administration Oral

Specifications of Care Maximum Strength 400mg Tablets 48

 

What Is Care Maximum Strength 400mg and What Is It Used For?

 

Care Maximum Strength 400mg Tablets contain ibuprofen, an NSAID used to relieve mild to moderate pain and reduce fever. They are indicated for a wide range of conditions including headache, dental pain, period pain, back pain, muscular aches, rheumatic pain, and the symptoms of colds and flu. Each tablet delivers 400mg of ibuprofen — the maximum strength available without a prescription in the UK.

 

What Do You Need to Know Before Using Care Maximum Strength 400mg?

 

Before taking these tablets, it's important to check whether they are appropriate for you. There are several situations where ibuprofen should be avoided entirely.

Do not take these tablets if you:

  • Are allergic to ibuprofen, aspirin, or any other NSAID
  • Have or have had a peptic ulcer or gastrointestinal bleeding
  • Are in the third trimester of pregnancy (weeks 28 onwards)
  • Have severe heart failure, kidney failure, or liver failure
  • Are under 12 years of age

Speak to your pharmacist or GP before use if you:

  • Have asthma, as NSAIDs can trigger bronchospasm in some people
  • Have a history of high blood pressure or cardiovascular disease
  • Are in the first or second trimester of pregnancy or are breastfeeding
  • Have inflammatory bowel disease (Crohn's disease or ulcerative colitis)
  • Have systemic lupus erythematosus (SLE)

Known drug interactions — take care if you are also taking:

  • Aspirin or other NSAIDs (increased risk of side effects)
  • Warfarin or other anticoagulants (increased bleeding risk)
  • Lithium (ibuprofen may increase lithium plasma levels)
  • Methotrexate (risk of toxicity increased)
  • Antihypertensives including ACE inhibitors and diuretics (reduced efficacy)
  • SSRIs (increased risk of gastrointestinal bleeding)

 

How Should You Use Care Maximum Strength 400mg Tablets?

 

Always take these tablets exactly as directed on the label or as advised by your pharmacist. Swallow each tablet whole with a full glass of water. Taking them with or after food helps to protect your stomach lining.

  1. Take one 400mg tablet with a full glass of water
  2. Take with or after food to reduce stomach irritation
  3. Wait at least 4–6 hours before taking another dose
  4. Do not exceed 3 tablets (1,200mg) in any 24-hour period
  5. Do not take for more than 3 days for fever or 10 days for pain without medical advice
Indication Age Group Dose Frequency
Pain / Fever Adults (18+) 400mg (1 tablet) Up to 3 times daily (every 4–6 hours)
Pain / Fever Adolescents (12–17) 400mg (1 tablet) Up to 3 times daily (every 6–8 hours)
Children under 12 Under 12 Not suitable Not applicable

 

What Are the Possible Side Effects of Care Maximum Strength 400mg?

 

Like all medicines, ibuprofen 400mg tablets can cause side effects, although not everyone experiences them. If you're managing ongoing discomfort alongside other conditions, our first aid range may also be helpful for minor injuries.

Common side effects (may affect up to 1 in 10 people):

  • Nausea or vomiting
  • Indigestion or heartburn
  • Stomach pain or discomfort
  • Diarrhoea or constipation
  • Flatulence

Less common side effects (may affect up to 1 in 100 people):

  • Headache or dizziness
  • Skin rash or itching
  • Fluid retention (oedema)
  • Raised blood pressure
  • Fatigue

Stop taking the tablets and seek immediate medical attention if you notice black or tarry stools, vomit that looks like coffee grounds, chest pain, difficulty breathing, or signs of a severe allergic reaction (swelling of the face, lips, or throat).

 

How Should You Store Care Maximum Strength 400mg Tablets?

 

  • Store below 25°C in a dry place away from direct heat and sunlight
  • Keep in the original blister packaging until ready to use
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the pack
  • Do not dispose of medicines via wastewater or household waste — return unused tablets to your pharmacy

If you're looking for complementary support for pain-related conditions, you might also find our IBS and cramps collection useful for managing abdominal discomfort alongside your pain relief routine.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy ibuprofen 400mg tablets online in the UK?

You can buy Care Maximum Strength 400mg Tablets directly from Cured Pharmacy, a GPhC-registered online pharmacy. Simply add the pack to your basket and choose your preferred delivery option. Browse our full pain relief collection for more options alongside this product.

How does ibuprofen 400mg work in the body?

Ibuprofen works by blocking COX-1 and COX-2 enzymes, which are responsible for producing prostaglandins — the chemicals that cause pain, swelling, and fever. By reducing prostaglandin levels, ibuprofen tackles inflammation at its source rather than simply dulling the sensation of pain. This dual anti-inflammatory and analgesic action makes it effective for a wide range of conditions.

What conditions can Care Maximum Strength 400mg tablets treat?

These tablets are indicated for headaches, dental pain, period pain (dysmenorrhoea), back pain, muscular aches, rheumatic pain, and mild fever. They can also help relieve the aches and pains associated with colds and flu. If your symptoms persist beyond the recommended treatment period, consult your GP or pharmacist.

What is the correct dose of Care Maximum Strength 400mg for adults?

Adults and adolescents aged 12 and over should take one 400mg tablet up to three times a day, with doses spaced at least 4–6 hours apart. The maximum dose is 1,200mg (three tablets) in any 24-hour period. Do not exceed this amount unless directed by a doctor.

Can I take ibuprofen 400mg tablets on an empty stomach?

It is strongly recommended to take ibuprofen with or after food to reduce the risk of stomach irritation, nausea, and indigestion. Taking it on an empty stomach increases the likelihood of gastrointestinal side effects. A full glass of water also helps the tablet dissolve properly and reach your system efficiently.

Who should not take ibuprofen 400mg tablets?

These tablets are not suitable for children under 12, people allergic to ibuprofen or other NSAIDs, those with a history of peptic ulcer or gastrointestinal bleeding, or anyone in the third trimester of pregnancy. People with severe heart, kidney, or liver failure should also avoid them. Always read the full patient information leaflet before use.

Can I take ibuprofen 400mg with paracetamol at the same time?

Yes, ibuprofen and paracetamol can generally be taken together because they work through different mechanisms and do not interact with each other directly. This combination is sometimes recommended by healthcare professionals for more effective pain management. Always check with your pharmacist first, particularly if you are taking other medicines.

What are the most common side effects of ibuprofen 400mg?

The most common side effects include nausea, indigestion, stomach pain, diarrhoea, and flatulence. These are more likely if you take ibuprofen on an empty stomach or at higher doses. Taking the tablets with food and plenty of water can help minimise these effects.

How do I manage side effects of Care Maximum Strength 400mg tablets?

To reduce stomach-related side effects, always take ibuprofen with food and a full glass of water. If you experience persistent indigestion, your pharmacist may recommend a stomach-protecting medicine such as a proton pump inhibitor. Stop taking the tablets and seek urgent medical advice if you notice any signs of gastrointestinal bleeding, such as black stools or vomiting blood.

Is ibuprofen 400mg safe to take during pregnancy?

Ibuprofen should be avoided during the third trimester of pregnancy (from 28 weeks) as it can harm the unborn baby and cause complications during labour. Use in the first and second trimesters should only occur on medical advice. If you are pregnant or trying to conceive, speak to your GP or midwife before taking any NSAID.

Can ibuprofen 400mg tablets be taken by people with asthma?

Some people with asthma are sensitive to NSAIDs including ibuprofen, and taking them can trigger bronchospasm or worsen asthma symptoms. If you have asthma, you must speak to your GP or pharmacist before taking ibuprofen 400mg tablets. Paracetamol is often recommended as a safer alternative for people with aspirin-sensitive asthma.

What medicines interact with ibuprofen 400mg tablets?

Ibuprofen can interact with several medicines including warfarin, aspirin, lithium, methotrexate, SSRIs, and antihypertensives such as ACE inhibitors and diuretics. These interactions can increase the risk of bleeding, reduce the effectiveness of blood pressure medicines, or raise the levels of other drugs in your blood. Always tell your pharmacist about all medicines you are taking before starting ibuprofen.

How long can you take ibuprofen 400mg tablets for?

For self-treatment, ibuprofen 400mg tablets should not be taken for more than 3 days to reduce a fever or more than 10 days for pain relief without consulting a doctor or pharmacist. Long-term use increases the risk of gastrointestinal, cardiovascular, and renal side effects. If your symptoms persist, seek professional medical advice rather than continuing to self-medicate.

What are the alternatives to ibuprofen 400mg tablets for pain relief?

Common alternatives include paracetamol (which is gentler on the stomach), aspirin (not suitable for under-16s), and naproxen (available OTC at lower doses). For topical pain relief, diclofenac gel or ibuprofen gel may be appropriate for localised muscle or joint pain. You can explore a range of options in our pain relief collection.

What happens if I miss a dose of ibuprofen 400mg?

If you miss a dose, simply take the next one when needed — as long as at least 4–6 hours have passed since your last tablet. Do not double up doses to make up for a missed one, as this increases the risk of side effects. Ibuprofen is taken as needed for pain or fever rather than on a strict schedule, so missing a dose is generally not a concern.

How Should You Use Care Maximum Strength 400mg Tablets?

Always read the patient information leaflet before taking these tablets. Swallow each tablet whole with a full glass of water — do not crush or chew them. Taking them with or after food is strongly recommended to protect your stomach lining and reduce the risk of irritation.

What Is the Correct Dose of Care Maximum Strength 400mg Tablets?

The dose varies depending on your age and the condition being treated. Always use the lowest effective dose for the shortest time necessary to control your symptoms. If you are unsure whether this dose is right for you, speak to your pharmacist before starting treatment.

When Is the Best Time to Use Care Maximum Strength 400mg Tablets?

There is no single "best" time of day to take ibuprofen — it should be taken when pain or fever is present and relief is needed. However, taking it with meals (breakfast, lunch, or dinner) is a practical way to remember your doses while also protecting your stomach. If you are taking it for period pain, starting at the first sign of discomfort rather than waiting for pain to peak tends to give better results.

For ongoing conditions such as back pain or rheumatic pain, try to space your doses evenly throughout the day to maintain consistent pain relief. Avoid taking a dose late at night on an empty stomach if possible.

How Long Can You Use Care Maximum Strength 400mg Tablets For?

These tablets are intended for short-term use only. For fever, do not take for more than 3 consecutive days without seeking medical advice. For pain relief, do not use for more than 10 days without consulting your GP or pharmacist. Prolonged use of ibuprofen increases the risk of gastrointestinal, cardiovascular, and renal complications, so it is important to reassess your symptoms regularly.

If your pain or fever does not improve within the recommended timeframe, or if symptoms worsen, stop taking the tablets and seek professional medical advice promptly. Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Care Maximum Strength 400mg Tablets?

Like all NSAIDs, ibuprofen 400mg tablets can cause side effects in some people, though many people tolerate them well when taken correctly. The most frequently reported side effects are gastrointestinal in nature and are more likely if you take the tablets on an empty stomach or at higher doses.

  • Nausea or feeling sick
  • Indigestion or heartburn
  • Stomach pain or discomfort
  • Diarrhoea
  • Constipation
  • Flatulence (wind)

What Are the Less Common Side Effects of Care Maximum Strength 400mg Tablets?

Less common side effects occur in fewer people but are still worth being aware of. If any of the following persist or become troublesome, speak to your pharmacist or GP.

  • Headache or dizziness
  • Skin rash, itching, or hives
  • Fluid retention causing ankle or leg swelling (oedema)
  • Raised blood pressure
  • Fatigue or drowsiness
  • Tinnitus (ringing in the ears)
  • Visual disturbances

What Are the Serious Side Effects of Care Maximum Strength 400mg Tablets?

Serious side effects are rare but require immediate medical attention. Stop taking the tablets straight away and call 999 or go to your nearest A&E if you experience any of the following.

  • Black, tarry, or blood-stained stools — a sign of gastrointestinal bleeding
  • Vomiting blood or material that looks like coffee grounds
  • Severe chest pain, shortness of breath, or sudden weakness — possible signs of a heart attack or stroke
  • Swelling of the face, lips, tongue, or throat (angioedema) — a sign of a serious allergic reaction
  • Severe skin reactions such as blistering or peeling
  • Significant reduction in urine output — a sign of kidney problems

What Should You Do If You Experience Side Effects?

For mild stomach-related side effects, try taking the tablets with food and a full glass of water. If indigestion is persistent, your pharmacist may suggest a stomach-protecting medicine. For any side effect that is severe, unexpected, or does not resolve, stop taking the tablets and seek medical advice promptly. You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Care Maximum Strength 400mg Tablets Interact With Other Medicines?

Yes. Ibuprofen has several clinically significant drug interactions that you should be aware of before starting treatment. Taking ibuprofen alongside aspirin or other NSAIDs increases the risk of gastrointestinal side effects. Combining it with warfarin or other anticoagulants raises the risk of bleeding. Ibuprofen can also increase plasma levels of lithium and methotrexate, potentially causing toxicity. It may reduce the effectiveness of antihypertensive medicines including ACE inhibitors, beta-blockers, and diuretics. SSRIs taken alongside ibuprofen further increase the risk of gastrointestinal bleeding. Always tell your pharmacist about every medicine, supplement, or herbal remedy you are taking before using these tablets.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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