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Calprofen Ibuprofen Suspension

Calprofen Ibuprofen Suspension

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  • ✔️ Relieves fever in children from 3 months and over
  • ✔️ Reduces teething pain and post-vaccination discomfort
  • ✔️ Anti-inflammatory action targets pain at its source
  • ✔️ Orange-flavoured liquid for easier administration to children
  • ✔️ Works within 30 minutes to lower elevated temperature

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Is Calprofen Ibuprofen Suspension for Children Right for Your Child?

 

When your child is running a temperature or crying with teething pain, you want something that works — and works safely. Ibuprofen suspension for children is one of the most widely used over-the-counter medicines for managing fever, mild to moderate pain, and inflammation in young children. Calprofen Ibuprofen Suspension contains 100mg of ibuprofen per 5ml and is suitable for children aged 3 months and over who weigh at least 5kg. It comes in a pleasant orange flavour, making it easier to give to little ones who might otherwise resist medicine.

Ibuprofen belongs to a class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It is widely recommended by healthcare professionals for short-term use in children and is available without a prescription from registered UK pharmacies. If you're looking for trusted baby and toddler health products, Calprofen is a well-established choice that parents and pharmacists rely on.

 

How Does Calprofen Ibuprofen Suspension Work?

 

Ibuprofen works by inhibiting enzymes called cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). These enzymes are responsible for producing prostaglandins — chemical messengers that trigger pain, fever, and inflammation in the body. By reducing prostaglandin production, ibuprofen helps to:

  • Lower elevated body temperature (antipyretic effect)
  • Reduce mild to moderate pain, including teething discomfort and headaches
  • Decrease localised inflammation, such as that caused by ear infections or sore throats
  • Provide relief that typically begins within 30 minutes of administration

The liquid formulation means the active ingredient is absorbed quickly through the gastrointestinal tract, making it particularly suitable for children who cannot swallow tablets.

 

Who Should Use Calprofen Ibuprofen Suspension?

 

Calprofen is designed specifically for children, not adults. It is appropriate for managing a range of common childhood conditions where pain or fever is present. It is particularly useful for:

  • Children aged 3 months to 12 years weighing at least 5kg
  • Fever following routine childhood vaccinations (from 2 months, under medical guidance)
  • Teething pain and associated discomfort
  • Mild to moderate pain from ear infections, sore throats, or headaches

It is not suitable for children under 3 months of age (except post-vaccination fever under medical supervision), those with known hypersensitivity to ibuprofen or aspirin, or children with certain kidney, liver, or heart conditions. Always read the label carefully before use.

 

How Does Calprofen Compare to Other Children's Pain Relief Options?

 

Feature Calprofen Ibuprofen Suspension Children's Paracetamol Suspension (e.g. Calpol)
Active ingredient Ibuprofen 100mg/5ml Paracetamol 120mg/5ml or 250mg/5ml
Minimum age 3 months (≥5kg) 2 months (≥4kg)
Anti-inflammatory action Yes (NSAID) No
Dosing frequency Every 6–8 hours, max 3 doses/day Every 4–6 hours, max 4 doses/day

 

How Should Calprofen Ibuprofen Suspension Be Stored?

 

Store Calprofen below 25°C in a dry place, away from direct sunlight. Do not refrigerate the suspension, as this can affect the consistency of the liquid. Always keep the bottle tightly closed and out of the reach and sight of children — medicines should never be left accessible to young ones. Check the expiry date before each use and do not use the product after the date shown on the packaging.

Once opened, Calprofen should be used within the period stated on the label — typically within a few months. If you're stocking up on children's health essentials, you might also want to explore our wider pain relief collection for other trusted options.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Calprofen Ibuprofen Suspension specifications
Treatment category Pain relief, antipyretic, anti-inflammatory
Mechanism of action COX-1 and COX-2 inhibitor (NSAID)
Effective for Fever, mild to moderate pain, inflammation
Suitable for Children aged 3 months and over (≥5kg)
Active ingredient Ibuprofen 100mg/5ml
Pack sizes 100ml, 150ml
Strengths 100mg/5ml
UK classification General Sale List (GSL)
Drug class Non-steroidal anti-inflammatory drug (NSAID)
Preparation Oral suspension
Route of administration Oral

Specifications of Calprofen Ibuprofen Suspension

 

What Is Calprofen Ibuprofen Suspension and What Is It Used For?

 

Calprofen Ibuprofen Suspension is an oral liquid medicine containing ibuprofen 100mg per 5ml. It is used to relieve fever, mild to moderate pain, and inflammation in children. Common reasons parents reach for it include post-vaccination fever, teething discomfort, sore throats, earache, and headaches. It is classified as a General Sale List (GSL) medicine in the UK, meaning it can be purchased without a prescription from registered pharmacies and retailers.

Ibuprofen suspension for children is one of the two main types of children's liquid pain relief available in the UK — the other being paracetamol suspension. Unlike paracetamol, ibuprofen also has anti-inflammatory properties, which can make it particularly useful when inflammation is part of the problem, such as with ear infections or teething.

 

What Do You Need to Know Before Using Calprofen Ibuprofen Suspension?

 

Before giving Calprofen to your child, it is important to check that it is safe for them. Do not use this medicine if any of the following apply:

  • Your child is under 3 months old or weighs less than 5kg
  • Your child has a known allergy to ibuprofen, aspirin, or any other NSAID
  • Your child has a history of asthma triggered by NSAIDs
  • Your child has active or previous stomach ulcers or gastrointestinal bleeding
  • Your child has severe kidney, liver, or heart failure
  • Your child is dehydrated or has significant blood loss

Speak to your pharmacist or GP before use if your child has chickenpox, as ibuprofen use during chickenpox has been associated with serious skin complications. Also seek advice if your child has any chronic health condition.

Be aware of the following potential drug interactions:

  • Aspirin and other NSAIDs — increased risk of side effects
  • Anticoagulants (e.g. warfarin) — may increase bleeding risk
  • ACE inhibitors and diuretics — ibuprofen may reduce their effectiveness
  • Corticosteroids — increased risk of gastrointestinal side effects
  • Methotrexate — ibuprofen may increase methotrexate toxicity

 

How Should You Use Calprofen Ibuprofen Suspension?

 

Always use the oral syringe or measuring device provided with the bottle. Do not use a household teaspoon, as this may result in an inaccurate dose. Follow these steps:

  1. Shake the bottle well before each use.
  2. Check your child's weight and age to determine the correct dose from the table below.
  3. Draw up the correct amount using the oral syringe.
  4. Administer the suspension directly into your child's mouth, aiming for the inside of the cheek.
  5. Give with or after food to reduce the chance of stomach upset.
  6. Wait at least 6 hours before giving the next dose.
  7. Do not give more than 3 doses in any 24-hour period.
Age Group Weight Dose (100mg/5ml) Frequency
3–6 months 5–7.6kg 2.5ml Up to 3 times daily
6–12 months 7.7–9kg 2.5ml Up to 3 times daily
1–3 years 10–15kg 5ml Up to 3 times daily
4–6 years 16–20kg 7.5ml Up to 3 times daily
7–9 years 21–28kg 10ml Up to 3 times daily
10–12 years 29–40kg 15ml Up to 3 times daily

If your child's symptoms do not improve within 24 hours of starting treatment, or if they worsen at any point, seek medical advice promptly. For broader children's health support, you may also find our cold and flu collection helpful during winter months.

 

What Are the Possible Side Effects of Calprofen Ibuprofen Suspension?

 

Like all medicines, Calprofen can cause side effects, although not every child will experience them. Knowing what to look out for helps you act quickly if something doesn't seem right.

Common side effects (may affect up to 1 in 10 children):

  • Nausea or stomach discomfort
  • Diarrhoea
  • Vomiting
  • Indigestion

Less common side effects (may affect up to 1 in 100 children):

  • Skin rash or itching
  • Headache
  • Dizziness
  • Mild allergic reactions

Stop use immediately and seek urgent medical attention if your child develops difficulty breathing, swelling of the face or throat, severe skin reactions, or signs of gastrointestinal bleeding such as blood in stools or vomit. These are rare but serious reactions that require prompt assessment.

 

How Should You Store Calprofen Ibuprofen Suspension?

 

  • Store below 25°C in a dry place away from direct heat and sunlight
  • Do not refrigerate — cold temperatures can affect the suspension
  • Keep the bottle tightly closed when not in use
  • Keep out of the reach and sight of children at all times
  • Do not use after the expiry date printed on the label
  • Do not dispose of medicines via wastewater or household waste — return unused medicine to your pharmacist

If you need additional first aid or health essentials for your family, take a look at our first aid collection for a range of trusted products.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Calprofen Ibuprofen Suspension online in the UK?

You can buy Calprofen Ibuprofen Suspension online from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available without a prescription for children aged 3 months and over who weigh at least 5kg. Simply add it to your basket and it will be dispatched quickly to your door.

How does Calprofen Ibuprofen Suspension work in the body?

Calprofen contains ibuprofen, an NSAID that works by blocking COX-1 and COX-2 enzymes, which are responsible for producing prostaglandins — the chemicals that cause pain, fever, and inflammation. By reducing prostaglandin levels, it helps bring down your child's temperature and ease discomfort. Effects typically begin within 30 minutes of giving the dose.

What age can children take Calprofen Ibuprofen Suspension?

Calprofen is suitable for children aged 3 months and over who weigh at least 5kg. For post-vaccination fever in babies aged 2 months, it may be used under medical guidance only. Always check the dosage table on the packaging and confirm with your pharmacist if you are unsure.

What is the correct dose of Calprofen for my child?

The dose is based on your child's age and weight. For example, children aged 3–12 months typically receive 2.5ml, while children aged 10–12 years may receive up to 15ml per dose. Always use the oral syringe provided and follow the dosage instructions on the packaging carefully — never guess the dose.

How often can I give my child Calprofen Ibuprofen Suspension?

You can give Calprofen every 6 to 8 hours as needed, but no more than 3 doses in any 24-hour period. Leave at least 6 hours between each dose. If your child's symptoms have not improved after 24 hours, seek advice from your GP or pharmacist.

Can I give Calprofen and paracetamol together to my child?

Ibuprofen and paracetamol work through different mechanisms and can sometimes be alternated to help manage persistent fever or pain in children. However, you should always speak to your pharmacist or GP before combining them to make sure it is appropriate for your child's age, weight, and condition. Never exceed the recommended dose of either medicine.

What are the side effects of Calprofen Ibuprofen Suspension?

Common side effects include stomach upset, nausea, vomiting, and diarrhoea. Less commonly, children may experience skin rash, headache, or dizziness. Stop use immediately and seek urgent medical help if your child develops difficulty breathing, facial swelling, or any signs of a serious allergic reaction.

How do I manage side effects of Calprofen Ibuprofen Suspension?

To reduce the risk of stomach upset, always give Calprofen with or after food. If your child experiences mild nausea or indigestion, this usually settles on its own. For any persistent or severe side effects, stop the medicine and contact your pharmacist or GP for advice.

Who should not use Calprofen Ibuprofen Suspension?

Calprofen should not be given to children under 3 months old, those weighing less than 5kg, or children with a known allergy to ibuprofen or aspirin. It is also not suitable for children with active stomach ulcers, severe kidney or liver problems, or asthma triggered by NSAIDs. Always check with your pharmacist if you are unsure. You can browse our baby and toddler collection for alternative options.

What happens if I give my child too much Calprofen?

If you think your child has received too much Calprofen, contact NHS 111 or go to your nearest A&E immediately — even if your child seems well. Overdose symptoms may include nausea, vomiting, stomach pain, and in severe cases, drowsiness or breathing difficulties. Always keep medicines out of reach of children.

What happens if I miss a dose of Calprofen?

If you miss a dose and your child is still in pain or has a fever, give the next dose as soon as you remember — but only if at least 6 hours have passed since the last dose. Do not give a double dose to make up for a missed one. If you are unsure, speak to your pharmacist.

What are alternatives to Calprofen Ibuprofen Suspension?

Alternatives include other children's ibuprofen suspensions such as Nurofen for Children, or paracetamol-based suspensions such as Calpol. The right choice depends on your child's age, weight, and medical history. You can explore our full pain relief range to compare options.

How long can I use Calprofen Ibuprofen Suspension for?

Calprofen is intended for short-term use only. For fever, do not use for more than 3 days without seeking medical advice. For pain, do not use for more than 3 days in children under 12 without consulting a doctor or pharmacist. Prolonged use without medical supervision is not recommended.

Is Calprofen Ibuprofen Suspension suitable for children with asthma?

Ibuprofen can trigger or worsen asthma symptoms in some children, particularly those who have previously reacted to aspirin or other NSAIDs. If your child has asthma, always speak to your GP or pharmacist before giving Calprofen. Paracetamol suspension is often recommended as a safer alternative for children with asthma.

What are the latest guidelines on using ibuprofen suspension for children in the UK?

Current NHS guidance recommends ibuprofen as a first-line option for fever and mild to moderate pain in children aged 3 months and over, provided there are no contraindications. The NHS advises against using ibuprofen in children with chickenpox due to the risk of serious skin infections. Always follow the most up-to-date advice from your pharmacist or GP.

How Should You Use Calprofen Ibuprofen Suspension?

Always use the oral syringe or measuring device supplied with the bottle — never a household teaspoon, as this can lead to inaccurate dosing. Give the suspension with or after food to help reduce the chance of stomach upset.

What Is the Correct Dose of Calprofen Ibuprofen Suspension?

Dosing is based on your child's age and weight. Always use the lowest effective dose for the shortest time necessary. Do not exceed 3 doses in any 24-hour period.

When Is the Best Time to Use Calprofen Ibuprofen Suspension?

Give Calprofen when your child is clearly uncomfortable — for example, when they have a raised temperature above 38°C, are in pain from teething, or are distressed following a vaccination. Giving it with or after a meal or snack is ideal, as this helps protect the stomach lining and reduces the likelihood of nausea. Avoid giving it on an empty stomach where possible.

If your child wakes in the night with fever or pain, it is safe to give a dose provided at least 6 hours have passed since the last one and no more than 3 doses have been given in the previous 24 hours.

How Long Can You Use Calprofen Ibuprofen Suspension For?

Calprofen is designed for short-term use only. For fever, do not use for more than 3 consecutive days without seeking medical advice. For pain relief, the same 3-day limit applies for children under 12 years. If your child's symptoms persist, worsen, or new symptoms develop, stop use and consult your GP or pharmacist promptly.

Prolonged or repeated use of ibuprofen without medical supervision is not recommended, as it may increase the risk of gastrointestinal or kidney-related side effects. Always use the minimum effective dose for the shortest duration needed.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Calprofen Ibuprofen Suspension?

Most children tolerate Calprofen well when used as directed, but like all medicines, it can cause side effects in some cases. Gastrointestinal symptoms are the most frequently reported. Giving the suspension with food can help reduce these effects.

  • Nausea
  • Vomiting
  • Stomach pain or discomfort
  • Diarrhoea
  • Indigestion

What Are the Less Common Side Effects of Calprofen Ibuprofen Suspension?

Less commonly, some children may experience the following side effects. These are not typical but are worth being aware of, particularly if your child has a history of allergies or skin sensitivities.

  • Skin rash or itching
  • Headache
  • Dizziness
  • Mild fluid retention
  • Mild allergic skin reactions

What Are the Serious Side Effects of Calprofen Ibuprofen Suspension?

Serious side effects are rare but require immediate medical attention. Stop giving Calprofen and seek urgent help if your child develops any of the following:

  • Difficulty breathing or wheezing (possible allergic reaction or asthma exacerbation)
  • Swelling of the face, lips, tongue, or throat (angioedema)
  • Severe skin reactions such as blistering or peeling
  • Blood in stools or vomit (signs of gastrointestinal bleeding)
  • Significant reduction in urine output (possible kidney effects)

If you suspect your child is having a serious allergic reaction, call 999 immediately. Do not wait to see if symptoms improve on their own.

What Should You Do If Your Child Experiences Side Effects?

For mild side effects such as stomach upset, try giving the next dose with food and ensure your child is well hydrated. If symptoms persist or you are concerned, stop the medicine and contact your pharmacist or GP. For any serious or unexpected reaction, seek medical attention without delay. You can also report suspected side effects to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Calprofen Ibuprofen Suspension Interact With Other Medicines?

Yes. Ibuprofen can interact with several other medicines, which is why it is important to tell your pharmacist about everything your child is currently taking — including vitamins, supplements, and herbal remedies. Key interactions to be aware of include aspirin and other NSAIDs (increased side effect risk), anticoagulants such as warfarin (increased bleeding risk), ACE inhibitors and diuretics (reduced effectiveness), corticosteroids (increased gastrointestinal risk), and methotrexate (increased toxicity risk). Always check with your pharmacist before combining medicines.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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