Skip to product information
1 of 1

  • Images are for illustration purposes only

Calpol Sixplus FastMelts Strawberry - 24 Tablets

Calpol Sixplus FastMelts Strawberry - 24 Tablets

  • 1. Ozempic®️-equivalent therapy now available for weight management
  • 2. Average weight loss of 17%, with 1 in 3 patients achieving over 20%
  • 3. May help reduce osteoarthritis-related pain
  • 4. Wegovy®️ is not expected to impact the effectiveness of oral contraceptives
  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Dissolves on the tongue — no water or measuring needed
  • ✔️ Relieves children's pain and fever from age 6 upwards
  • ✔️ Each tablet delivers 250mg paracetamol for effective symptom control
  • ✔️ Strawberry flavour improves palatability for reluctant children
  • ✔️ Sugar-free formula suitable for children managing sugar intake

Price Checker

Regular price £7.09
Sale price £7.09
Sale Sold out
  • Lowest price guarantee
  • Includes FREE private prescription
View full details

 

What Are Calpol Sixplus FastMelts and How Do They Help?

 

When your child is unwell — running a temperature, complaining of a headache, or aching after a vaccination — you want something that works quickly and that they'll actually take. Calpol Sixplus FastMelts are strawberry-flavoured dissolving paracetamol tablets designed specifically for children aged 6 and over. Each tablet contains 250mg of paracetamol and melts directly on the tongue, meaning no water is needed and no fuss with measuring spoons. For parents managing a poorly child, that convenience genuinely matters. You can find this product and other children's medicines in our baby and toddler collection.

Paracetamol has been used safely in children for decades and remains one of the most widely recommended medicines for childhood pain and fever by the NHS. These tablets are particularly useful for children who struggle to swallow capsules or who dislike liquid medicines — the fast-melt format dissolves in seconds, making the whole experience far less stressful for everyone involved.

 

How Does Paracetamol in Calpol Sixplus FastMelts Work?

 

Paracetamol works centrally in the brain and nervous system. It is thought to inhibit the synthesis of prostaglandins — chemical messengers that sensitise pain receptors and contribute to fever. By reducing prostaglandin activity, paracetamol lowers the perception of pain and helps bring a raised temperature back down to normal.

  • The tablet is placed on the tongue and dissolves rapidly without water.
  • Paracetamol is absorbed through the gastrointestinal tract after swallowing.
  • Pain relief and fever reduction typically begin within 30 to 60 minutes of taking the dose.
  • The effect generally lasts 4 to 6 hours, after which a further dose may be given if needed.

 

Who Is Calpol Sixplus FastMelts Suitable For?

 

These tablets are intended for children aged 6 to 12 years. They are particularly well suited to children who find liquid medicines unpleasant or who are old enough to manage a dissolving tablet safely. They are not appropriate for children under 6 — for younger children, age-appropriate Calpol liquid formulations are available.

  • Children aged 6 to 12 years experiencing mild to moderate pain.
  • Children with a fever (high temperature) requiring symptomatic relief.
  • Children who dislike swallowing tablets or measuring liquid medicines.
  • Children recovering from vaccinations or minor illnesses such as colds.

 

How Do Calpol Sixplus FastMelts Compare to Calpol Sixplus Suspension?

 

Feature Calpol Sixplus FastMelts Calpol Sixplus Suspension
Active ingredient Paracetamol 250mg per tablet Paracetamol 250mg per 5ml
Format Dissolving tablet (no water needed) Oral liquid (requires measuring)
Age range 6 to 12 years 6 to 12 years
Convenience Portable, no spoon or water required Requires measuring device

 

How Should You Store Calpol Sixplus FastMelts and Are They Safe to Keep at Home?

 

Store Calpol Sixplus FastMelts below 25°C in a dry place, away from direct sunlight. Always keep medicines out of the sight and reach of children — even medicines designed for children can cause serious harm if taken in excess. Check the expiry date on the packaging before use and do not use the product after the stated date.

If you are building a home medicine cabinet, it is worth pairing children's pain relief with other essentials. Our pain relief collection includes a range of options for both adults and children. Always read the patient information leaflet supplied with the product before use.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Calpol Sixplus FastMelts Strawberry 24 Tablets specifications
Treatment category Pain relief and fever reduction in children
Mechanism of action Inhibits prostaglandin synthesis; reduces pain and fever centrally
Effective for Mild to moderate pain, fever, headache, toothache, sore throat, post-vaccination discomfort
Suitable for Children aged 6 to 12 years
Active ingredient Paracetamol 250mg per tablet
Pack size 24 tablets
Strength 250mg paracetamol per tablet
UK classification General Sale List (GSL)
Drug class Analgesic / Antipyretic
Preparation Orodispersible tablet (fast-melt)
Route of administration Oral (dissolves on tongue)

Specifications of Calpol Sixplus FastMelts Strawberry 24 Tablets

 

What Is Calpol Sixplus FastMelts and What Is It Used For?

 

Calpol Sixplus FastMelts are orodispersible (fast-dissolving) paracetamol tablets containing 250mg of paracetamol per tablet. They are used to relieve mild to moderate pain and to reduce fever in children aged 6 to 12 years. Conditions they are commonly used for include headache, toothache, sore throat, earache, cold and flu symptoms, and discomfort following vaccinations. The strawberry flavour and dissolving format make them a practical choice for children who resist liquid medicines or cannot yet swallow whole tablets.

 

What Do You Need to Know Before Using Calpol Sixplus FastMelts?

 

Before giving these tablets to your child, read the following carefully. There are situations where this medicine should not be used, and others where extra caution is needed.

Do not use Calpol Sixplus FastMelts if your child:

  • Is under 6 years of age.
  • Is allergic to paracetamol or any other ingredient in the tablet.
  • Is already taking another medicine containing paracetamol — this includes many cold and flu remedies.
  • Has severe liver or kidney disease (unless directed by a doctor).

Use with caution and speak to a pharmacist or doctor first if your child:

  • Has liver or kidney problems.
  • Is underweight or malnourished.
  • Has phenylketonuria — the tablets contain aspartame.
  • Is taking warfarin or other anticoagulant medicines.

Known drug interactions:

  • Warfarin — regular use of paracetamol may enhance the anticoagulant effect.
  • Other paracetamol-containing products — concurrent use risks overdose.
  • Metoclopramide or domperidone — may increase the rate of paracetamol absorption.
  • Cholestyramine — may reduce paracetamol absorption if taken within one hour.

 

How Should You Use Calpol Sixplus FastMelts?

 

Always follow the dosage instructions on the packaging or as directed by your pharmacist. Do not exceed the stated dose. If your child's symptoms persist for more than 3 days, or worsen at any point, seek medical advice.

  1. Check your child's age and weight to confirm the correct dose.
  2. Remove one tablet from the blister pack with dry hands.
  3. Place the tablet directly on your child's tongue.
  4. Allow the tablet to dissolve completely — no water is required.
  5. Note the time of the dose and do not repeat within 4 hours.
  6. Do not give more than 4 doses in any 24-hour period.
Age Group Dose (tablets) Frequency Max doses per 24 hours
6 to 9 years 2 tablets (500mg) Every 4–6 hours 4 doses
10 to 12 years 3 tablets (750mg) Every 4–6 hours 4 doses
Under 6 years Not suitable

If your child is also suffering from cold or flu symptoms alongside pain or fever, you may find our cold and flu collection helpful for additional symptom relief options suitable for older children and adults.

 

What Are the Possible Side Effects of Calpol Sixplus FastMelts?

 

Paracetamol is generally very well tolerated when used at the recommended dose. Side effects are uncommon, but it is important to know what to look out for.

Common side effects (may affect up to 1 in 10 people):

  • Nausea (feeling sick) — usually mild.
  • Stomach discomfort.

Less common or rare side effects:

  • Skin rash or itching — stop use and seek medical advice.
  • Allergic reactions including swelling of the face, lips, or throat — seek emergency help immediately.
  • Blood disorders (very rare) — signs include unusual bruising or persistent sore throat.
  • Liver damage — only a risk with overdose; never exceed the recommended dose.

If you suspect your child has taken too much paracetamol, go to A&E immediately or call 999, even if they seem well. Paracetamol overdose can cause serious liver damage that may not be apparent for several days.

 

How Should You Store Calpol Sixplus FastMelts?

 

  • Store below 25°C in a dry place.
  • Keep away from direct sunlight and moisture.
  • Keep out of the sight and reach of children at all times.
  • Do not use after the expiry date printed on the packaging.
  • Do not dispose of medicines via wastewater or household waste — return unused medicines to your pharmacy.

Keeping a well-stocked medicine cabinet is sensible for any family. Alongside children's pain relief, consider browsing our first aid collection for plasters, antiseptic creams, and other household essentials.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Calpol Sixplus FastMelts online in the UK?

You can buy Calpol Sixplus FastMelts directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. They are available without a prescription as a General Sale List medicine. Simply add them to your basket and they will be dispatched to your door.

How do Calpol Sixplus FastMelts work in the body?

Each tablet contains 250mg of paracetamol, which works by inhibiting prostaglandin synthesis in the brain and central nervous system. This reduces the sensation of pain and helps lower a raised temperature. The fast-melt format dissolves on the tongue, allowing the paracetamol to be absorbed through the digestive tract in the usual way.

How do I use Calpol Sixplus FastMelts step by step?

Remove a tablet from the blister pack with dry hands and place it directly on your child's tongue. Allow it to dissolve fully — no water is needed. Record the time of the dose and do not repeat it within 4 hours, giving no more than 4 doses in any 24-hour period.

What is the correct dose of Calpol Sixplus FastMelts for my child?

Children aged 6 to 9 years should receive 2 tablets (500mg paracetamol) per dose. Children aged 10 to 12 years should receive 3 tablets (750mg paracetamol) per dose. Both age groups can have doses repeated every 4 to 6 hours, up to a maximum of 4 doses in 24 hours. Never exceed the stated dose.

Can I give Calpol Sixplus FastMelts to a child under 6 years old?

No — these tablets are not suitable for children under 6 years of age. For younger children, age-appropriate Calpol liquid suspensions are available. Always check the age range on the packaging before giving any medicine to a child.

What are the side effects of Calpol Sixplus FastMelts?

Side effects are uncommon at the recommended dose. Mild nausea or stomach discomfort may occasionally occur. Rarely, paracetamol can cause allergic skin reactions — if your child develops a rash, hives, or facial swelling, stop the medicine and seek medical advice promptly.

Can Calpol Sixplus FastMelts be given alongside other medicines?

Do not give these tablets at the same time as any other product containing paracetamol, including many cold and flu remedies, as this risks accidental overdose. If your child takes warfarin or any regular prescribed medicine, speak to a pharmacist before use. You can browse our cold and flu range for compatible symptom relief options.

What should I do if my child takes too many Calpol Sixplus FastMelts?

Go to your nearest A&E department immediately or call 999, even if your child appears well. Paracetamol overdose can cause serious liver damage that may not show symptoms for several days. Take the packaging with you so medical staff can see exactly what was taken and how much.

What are the alternatives to Calpol Sixplus FastMelts?

Alternatives include Calpol Sixplus oral suspension (liquid paracetamol), ibuprofen-based children's medicines such as Nurofen for Children (suitable for children aged 3 months and over, subject to weight), or generic paracetamol suspensions. You can explore a wider range of options in our pain relief collection. Always choose a product appropriate for your child's age and weight.

Do Calpol Sixplus FastMelts contain sugar or allergens?

Calpol Sixplus FastMelts are sugar-free, which makes them suitable for children who need to limit sugar intake. However, they do contain aspartame, a source of phenylalanine — they should not be given to children with phenylketonuria (PKU). Always check the full ingredients list on the packaging if your child has known allergies or intolerances.

How quickly do Calpol Sixplus FastMelts start working?

Paracetamol typically begins to relieve pain and reduce fever within 30 to 60 minutes of taking the dose. The fast-melt format dissolves rapidly on the tongue, but the speed of absorption into the bloodstream is similar to other oral paracetamol formulations. Effects generally last 4 to 6 hours.

How long can my child keep taking Calpol Sixplus FastMelts?

These tablets are intended for short-term use only. For pain, do not use for more than 3 days without seeking medical advice. For fever, do not use for more than 3 days without consulting a doctor. If symptoms persist or worsen, always speak to your GP or pharmacist.

What happens if I miss a dose of Calpol Sixplus FastMelts?

If you miss a dose and your child is still in pain or has a fever, you can give the next dose as soon as you remember — provided at least 4 hours have passed since the last dose. Never give a double dose to make up for a missed one. Keep track of doses carefully to avoid accidental overdose.

Are Calpol Sixplus FastMelts suitable for children with kidney or liver problems?

Children with significant liver or kidney disease should not be given paracetamol without first consulting a doctor or pharmacist. In these cases, the dose may need to be reduced or the interval between doses extended. Always disclose any existing medical conditions before starting any new medicine.

What is the latest guidance on using paracetamol for children's fever?

Current NHS guidance recommends paracetamol as a first-line option for relieving discomfort and reducing fever in children. It is not recommended to give paracetamol solely to prevent fever after vaccination unless the child is distressed. The NHS advises that fever itself is not always harmful and that treating the child's comfort, rather than the number on the thermometer, should guide use.

How Should You Use Calpol Sixplus FastMelts?

Calpol Sixplus FastMelts are designed to be placed directly on your child's tongue, where they dissolve quickly without the need for water. Always read the patient information leaflet before use and check that the product is appropriate for your child's age. Never give these tablets to a child under 6 years old.

What Is the Correct Dose of Calpol Sixplus FastMelts?

The dose depends on your child's age. Always use the lowest effective dose for the shortest time necessary. Do not give more than 4 doses in any 24-hour period, and leave at least 4 hours between each dose.

When Is the Best Time to Use Calpol Sixplus FastMelts?

Give the tablets as soon as your child begins to show signs of pain or fever — there is no need to wait until symptoms become severe. Paracetamol typically starts working within 30 to 60 minutes, so giving a dose promptly can help your child feel more comfortable sooner. If your child wakes in the night with a fever or pain, a dose can be given at that time provided at least 4 hours have passed since the previous dose.

There is no specific time of day that is considered optimal — timing should be guided by your child's symptoms and the 4-hour minimum interval between doses.

How Long Can You Use Calpol Sixplus FastMelts For?

These tablets are intended for short-term use only. Do not use them for pain relief for more than 3 consecutive days without seeking medical advice. Similarly, if your child's fever has not improved within 3 days, or if it worsens at any point, consult your GP. Prolonged or frequent use of paracetamol without medical supervision is not recommended.

If your child's condition does not improve or you have any concerns about their health, always seek professional medical advice promptly rather than continuing to self-treat.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)

What Are the Most Common Side Effects of Calpol Sixplus FastMelts?

Paracetamol is one of the most widely used medicines in the UK and is generally very well tolerated in children when used at the correct dose. Serious side effects are rare. That said, it is important to be aware of what can occasionally occur so you can act quickly if needed.

  • Nausea (feeling sick) — usually mild and short-lived.
  • Stomach discomfort or abdominal pain.

What Are the Less Common Side Effects of Calpol Sixplus FastMelts?

Less common reactions are infrequent but worth knowing about. If your child develops any of the following, stop giving the tablets and seek medical advice.

  • Skin rash or itching.
  • Hives (urticaria) — raised, itchy welts on the skin.
  • Flushing or redness of the skin.
  • Low blood pressure (hypotension) — very rare.

What Are the Serious Side Effects of Calpol Sixplus FastMelts?

Serious side effects from paracetamol at recommended doses are very rare. However, they can occur and require immediate medical attention. The most significant risk is liver damage, which is associated with overdose rather than therapeutic use — this is why it is critical never to exceed the stated dose and never to give paracetamol alongside other paracetamol-containing products.

  • Severe allergic reaction (anaphylaxis) — signs include swelling of the face, lips, tongue, or throat, difficulty breathing, or collapse. Call 999 immediately.
  • Blood disorders (very rare) — signs include unusual bruising, persistent sore throat, or unexplained fatigue.
  • Liver damage — only a risk in overdose situations. Symptoms may be delayed by several days.

What Should You Do If Your Child Experiences Side Effects?

For mild side effects such as nausea, stop the dose and monitor your child. If symptoms resolve, you may continue with the next scheduled dose. For any skin reactions, stop the medicine immediately and consult a pharmacist or GP before giving any further doses. If you suspect a serious allergic reaction or overdose, call 999 or go to A&E without delay — do not wait to see if symptoms improve on their own.

If you are ever unsure whether a symptom is related to the medicine, it is always safer to seek professional advice. Your pharmacist can help you assess whether it is safe to continue.

Can Calpol Sixplus FastMelts Interact With Other Medicines?

Yes. The most important interaction to be aware of is with other paracetamol-containing products. Many over-the-counter cold, flu, and cough remedies contain paracetamol — giving these alongside Calpol Sixplus FastMelts can lead to accidental overdose. Always check the ingredients of any other medicine your child is taking. Warfarin (an anticoagulant) may be affected by regular paracetamol use, and medicines such as metoclopramide or domperidone can alter the rate at which paracetamol is absorbed. Speak to your pharmacist if your child is on any regular medication.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

We’re a safe and
regulated UK service

Registered Pharmacy Badge

Lowest Price Guarantee

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

100% discreet packaging

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

Agent

Need help?
Talk to our friendly experts now

How our service works

Service Setup

Service setup

Discreet Packaging

Discreet packaging

Express Delivery

Express delivery