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Brolene 0.1% Eye Drops 10ml

Brolene 0.1% Eye Drops 10ml

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  • ✔️ Treats minor bacterial conjunctivitis with antiseptic propamidine isethionate
  • ✔️ Suitable for adults and children aged 2 years and over
  • ✔️ Clears sticky eye discharge and redness within 2 days
  • ✔️ Available over the counter — no prescription required
  • ✔️ Sterile 10ml bottle with 28-day use period after opening

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What Are Brolene Eye Drops and How Do They Help?

 

Brolene eye drops are a trusted over-the-counter treatment for minor bacterial eye infections, including conjunctivitis (commonly known as "pink eye"). Each 10ml bottle contains propamidine isethionate 0.1%, an antiseptic agent with a long history of use in UK pharmacy practice. If your eyes are red, sticky, or uncomfortable — and you're wondering whether you need a prescription — the good news is that Brolene is available without one for adults and children over 2 years of age. You can browse our full range of eye care products at Cured Pharmacy if you're looking for additional support alongside treatment.

Minor eye infections are surprisingly common. The NHS estimates that conjunctivitis affects millions of people in the UK each year, and most cases resolve with appropriate antiseptic or antibiotic treatment. Brolene offers a convenient first-line option when symptoms are mild and there's no sign of a more serious underlying condition.

 

How Do Brolene Eye Drops Work Against Eye Infections?

 

The active ingredient, propamidine isethionate, belongs to a class of compounds called diamidines. It works by disrupting the integrity of bacterial cell membranes, which ultimately kills the bacteria responsible for the infection. It is particularly effective against gram-positive bacteria commonly associated with superficial eye infections.

  • Propamidine isethionate penetrates the outer layers of bacterial cells
  • It interferes with cell membrane function, causing leakage of cellular contents
  • Bacteria are unable to survive this disruption, clearing the infection from the eye surface
  • The antiseptic action is localised to the eye, minimising systemic absorption

 

Who Should Use Brolene Eye Drops?

 

Brolene is suitable for adults and children aged 2 years and over who are experiencing mild symptoms of a bacterial eye infection. It is not appropriate for viral or allergic conjunctivitis — if you're unsure which type you have, a pharmacist can help you decide. If symptoms are severe, involve vision changes, or affect a newborn, you should seek medical advice rather than self-treating.

  • Adults with mild bacterial conjunctivitis
  • Children aged 2 years and over (with parental supervision)
  • People who need a quick, prescription-free option for a minor eye infection
  • Those who have previously used propamidine isethionate without adverse reactions

 

How Do Brolene Eye Drops Compare to Chloramphenicol Eye Drops?

 

Feature Brolene 0.1% Eye Drops Chloramphenicol 0.5% Eye Drops
Active ingredient Propamidine isethionate 0.1% Chloramphenicol 0.5%
Drug class Antiseptic (diamidine) Antibiotic (broad-spectrum)
Minimum age 2 years 2 years
Prescription required? No (OTC) No (OTC)

 

How Should You Store Brolene Eye Drops and Are They Safe Long-Term?

 

Store your bottle of Brolene eye drops below 25°C, away from direct sunlight. Do not refrigerate. Once opened, the drops should be discarded after 28 days — even if liquid remains — to reduce the risk of contamination and secondary infection. Always check the expiry date printed on the packaging before use.

If you are managing multiple eye care products or have a history of recurrent eye infections, it's worth speaking to your GP or pharmacist about longer-term management. You might also find it helpful to explore our allergy and hay fever range if seasonal allergies are contributing to your eye symptoms, as allergic and bacterial conjunctivitis can sometimes occur together.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Brolene 0.1% Eye Drops 10ml specifications
Treatment category Minor bacterial eye infections, conjunctivitis
Active ingredient Propamidine isethionate 0.1%
Mechanism of action Antiseptic — disrupts bacterial cell membranes
Drug class Diamidine antiseptic
Strengths 0.1% w/v
Pack sizes 10ml
Route of administration Ophthalmic (topical eye drops)
UK classification General Sale List (GSL) / Pharmacy (P) medicine
Suitable for Adults and children aged 2 years and over
Preparation Sterile aqueous eye drop solution

Specifications of Brolene 0.1% Eye Drops 10ml

 

What Is Brolene 0.1% Eye Drops and What Is It Used For?

 

Brolene 0.1% Eye Drops contain the active ingredient propamidine isethionate, an antiseptic used to treat minor bacterial infections of the eye and eyelids. It is most commonly used for bacterial conjunctivitis — an infection that causes redness, discharge, and crusting around the eye. The drops work on the surface of the eye and are not absorbed into the bloodstream in any meaningful quantity, making them suitable for short-term self-treatment in most healthy adults and children over 2 years.

Conjunctivitis caused by bacteria typically presents with a yellow or green sticky discharge, particularly in the morning. If your symptoms match this description and are mild, Brolene eye drops may be an appropriate first-line treatment. However, if you experience pain, sensitivity to light, or any change in vision, you should seek medical attention promptly rather than self-treating.

 

What Do You Need to Know Before Using Brolene Eye Drops?

 

Before using these drops, it's important to check whether they are appropriate for you. Do not use Brolene eye drops if any of the following apply:

  • You are allergic to propamidine isethionate or any other ingredient in the formulation
  • You are wearing soft contact lenses (the preservative benzalkonium chloride can damage soft lens material)
  • The affected person is under 2 years of age
  • You have a penetrating eye injury or foreign body in the eye
  • You have been diagnosed with a viral or fungal eye infection — Brolene is not effective against these
  • You are pregnant or breastfeeding — seek pharmacist or GP advice before use

There are no widely documented significant drug interactions with Brolene eye drops at standard OTC doses. However, if you are using other eye drops or eye ointments, allow at least 5 minutes between applications to avoid diluting either product. Known interactions to be aware of include:

  • Other topical ophthalmic preparations — stagger application times
  • Soft contact lenses — remove before use and wait at least 15 minutes before reinserting

 

How Should You Use Brolene Eye Drops?

 

Always follow the instructions on the packaging or as directed by your pharmacist. The standard method of application is as follows:

  1. Wash your hands thoroughly with soap and water before handling the bottle
  2. Tilt your head back slightly and look upward
  3. Gently pull down your lower eyelid to create a small pocket
  4. Hold the bottle above the eye without touching the tip to your eye or eyelid
  5. Squeeze one to two drops into the pocket formed by the lower eyelid
  6. Close your eye gently and press lightly on the inner corner for one minute to prevent the drops draining away
  7. Repeat in the other eye if both are affected
  8. Replace the cap immediately after use
Indication Age Group Dose Frequency
Minor bacterial conjunctivitis Adults and children ≥2 years 1–2 drops per affected eye Up to 4 times daily
Minor eyelid infection (blepharitis) Adults 1–2 drops per affected eye Up to 4 times daily

If you are also managing other eye conditions, our eye care collection includes a range of products that may complement your treatment plan.

 

What Are the Possible Side Effects of Brolene Eye Drops?

 

Like all medicines, Brolene eye drops can cause side effects, although not everyone experiences them. Most side effects are mild and temporary.

Common side effects (may affect up to 1 in 10 people):

  • Temporary stinging or burning sensation immediately after instillation
  • Mild eye irritation or discomfort
  • Transient blurred vision immediately after application

Less common side effects (may affect fewer than 1 in 100 people):

  • Localised allergic reaction — redness, swelling, or itching around the eye
  • Increased sensitivity to light (photophobia)
  • Prolonged or worsening redness of the eye

Stop using the drops and seek medical advice immediately if you experience severe eye pain, sudden changes in vision, or signs of a serious allergic reaction such as swelling of the face or difficulty breathing. These reactions are rare but require prompt attention.

 

How Should You Store Brolene Eye Drops?

 

Correct storage helps maintain the effectiveness and sterility of the drops. If you're managing several medicines at home, it's worth reviewing your storage habits for all of them — including any first aid products you keep in your medicine cabinet.

  • Store below 25°C in a cool, dry place
  • Do not refrigerate or freeze
  • Keep away from direct sunlight and heat sources
  • Keep the bottle tightly closed when not in use
  • Discard the bottle 28 days after first opening, even if drops remain
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the label

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Brolene eye drops online in the UK?

You can buy Brolene 0.1% Eye Drops online from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £4.99. They are available without a prescription as an over-the-counter medicine. Browse our full eye care collection for more options to support your eye health.

How do Brolene eye drops work in the eye?

Brolene eye drops contain propamidine isethionate 0.1%, an antiseptic that works by disrupting the cell membranes of bacteria on the surface of the eye. This kills the bacteria responsible for minor infections such as conjunctivitis. The action is localised to the eye surface, so systemic absorption is minimal.

How do I use Brolene eye drops step by step?

Wash your hands, tilt your head back, and gently pull down your lower eyelid to form a small pocket. Squeeze one to two drops into the pocket without touching the bottle tip to your eye, then close your eye gently and press lightly on the inner corner for one minute. Replace the cap immediately and repeat in the other eye if needed.

How many times a day should I use Brolene eye drops?

The recommended dose for adults and children aged 2 years and over is one to two drops into the affected eye(s) up to four times daily. Space applications evenly throughout the day for best results. Do not exceed four applications per day unless specifically advised by a healthcare professional.

What are the side effects of Brolene eye drops?

The most commonly reported side effects are temporary stinging, burning, or mild irritation immediately after instilling the drops, as well as brief blurred vision. Less commonly, some people experience localised allergic reactions such as redness or swelling around the eye. If you notice severe pain, vision changes, or signs of a serious allergic reaction, stop use and seek medical advice promptly.

Can I use Brolene eye drops if I wear contact lenses?

No — you should remove soft contact lenses before instilling Brolene eye drops, as the preservative benzalkonium chloride can be absorbed by soft lens material and cause irritation. Wait at least 15 minutes after applying the drops before reinserting your lenses. Hard (rigid gas-permeable) lenses should also be removed prior to use; check with your optician if you are unsure.

How long can I use Brolene eye drops for?

Brolene eye drops should not be used for more than 2 days without seeing an improvement in symptoms. If your eye infection is not improving after 2 days of treatment, stop using the drops and consult a pharmacist or GP, as you may need a different or stronger treatment such as a prescription antibiotic. Prolonged self-treatment without medical review is not recommended.

What happens if I miss a dose of Brolene eye drops?

If you forget to apply a dose, use the drops as soon as you remember — unless it is nearly time for your next scheduled dose, in which case simply skip the missed one. Do not apply a double dose to make up for a missed application. Keeping to a regular schedule (for example, morning, midday, afternoon, and evening) makes it easier to remember.

Are Brolene eye drops safe during pregnancy or breastfeeding?

There is limited clinical data on the use of propamidine isethionate during pregnancy or breastfeeding. If you are pregnant, trying to conceive, or breastfeeding, you should speak to your GP or pharmacist before using Brolene eye drops. They can advise on the most appropriate and safest treatment option for your situation.

Can children use Brolene eye drops?

Yes, Brolene eye drops are suitable for children aged 2 years and over, used under adult supervision. They should not be used in babies or children under 2 years of age without specific medical advice. If your child's symptoms are severe, involve both eyes, or do not improve within 2 days, seek advice from a GP or pharmacist.

What are the alternatives to Brolene eye drops for conjunctivitis?

The main over-the-counter alternative for bacterial conjunctivitis in the UK is chloramphenicol 0.5% eye drops, which is a broad-spectrum antibiotic. Your pharmacist can help you decide which is more appropriate based on your symptoms and medical history. If your conjunctivitis is allergic rather than bacterial, antihistamine eye drops or sodium cromoglicate drops may be more suitable — you can explore related options in our allergy and hay fever range.

How should I store Brolene eye drops after opening?

Once opened, Brolene eye drops should be stored below 25°C, away from direct sunlight and heat. Do not refrigerate the bottle. Discard the drops 28 days after first opening, even if liquid remains, to prevent the risk of contamination and secondary infection. Always check the expiry date on the packaging before use.

Is Brolene the same as chloramphenicol eye drops?

No — Brolene and chloramphenicol eye drops are different products with different active ingredients. Brolene contains propamidine isethionate, an antiseptic, while chloramphenicol is a broad-spectrum antibiotic. Both are available over the counter for minor bacterial eye infections, but they work through different mechanisms and may suit different patients depending on their history and symptoms.

What is the latest guidance on treating conjunctivitis in the UK?

Current NHS guidance recommends that most cases of bacterial conjunctivitis in adults and children over 2 years can be managed with over-the-counter antiseptic or antibiotic eye drops without the need for a GP appointment. The NHS also advises good hygiene practices — such as not sharing towels and washing hands frequently — to prevent spreading the infection. If symptoms are severe or do not resolve within a few days, a GP review is recommended.

Can I use Brolene eye drops for a stye or eyelid infection?

Brolene eye drops may be used for minor eyelid infections such as blepharitis (inflammation of the eyelid margins) in adults, as propamidine isethionate has antiseptic properties that can help reduce bacterial load on the eyelid. However, styes (hordeola) are typically caused by a blocked gland rather than a surface infection, and warm compresses are usually the first-line recommendation. Speak to a pharmacist if you are unsure whether Brolene is appropriate for your specific condition.

How Should You Use Brolene Eye Drops?

Using Brolene eye drops correctly makes a real difference to how quickly your infection clears. Always wash your hands before and after handling the bottle, and never allow the dropper tip to touch your eye, eyelid, or any other surface, as this can introduce bacteria into the solution.

What Is the Correct Dose of Brolene Eye Drops?

The standard dose is one to two drops per affected eye, applied up to four times daily. Do not apply more drops than recommended, as this will not speed up recovery and may increase the risk of irritation.

When Is the Best Time to Use Brolene Eye Drops?

Space your doses evenly throughout the day to maintain a consistent antiseptic effect on the eye surface. A practical schedule might be morning, midday, late afternoon, and before bed — this keeps the intervals roughly equal and makes it easier to remember each dose.

If you are using other eye drops at the same time, wait at least 5 minutes between different products to prevent one diluting the other. Apply Brolene eye drops before any eye ointments, as ointments can form a barrier that reduces absorption of drops applied afterwards.

How Long Can You Use Brolene Eye Drops For?

You should see a noticeable improvement in your symptoms within 2 days of starting treatment. If there is no improvement after 2 days, or if your symptoms worsen at any point, stop using the drops and consult a pharmacist or GP — a different treatment may be needed.

Do not continue using Brolene eye drops beyond 2 days without medical advice, and always discard the bottle 28 days after first opening regardless of how much liquid remains. Continuing to use an opened bottle beyond this point risks contamination and could worsen your eye condition.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Brolene Eye Drops?

Most people who use Brolene eye drops tolerate them well, but some mild side effects can occur, particularly immediately after instillation. These are usually short-lived and settle within a few minutes.

  • Temporary stinging or burning sensation in the eye
  • Mild eye irritation or discomfort
  • Brief blurred vision immediately after applying the drops

If you experience blurred vision after applying the drops, avoid driving or operating machinery until your vision has fully cleared. This effect is temporary and typically resolves within a few minutes of application.

What Are the Less Common Side Effects of Brolene Eye Drops?

Less commonly, some people may experience a localised reaction around the eye. These side effects are not typical but are worth being aware of before you start treatment.

  • Redness or swelling of the eyelid or surrounding skin
  • Itching or a sensation of grittiness in the eye
  • Increased sensitivity to light (photophobia)
  • Watering of the eye beyond what is expected from the infection itself

What Are the Serious Side Effects of Brolene Eye Drops?

Serious side effects from Brolene eye drops are rare, but you should be aware of the signs that indicate something more significant may be happening. Stop using the drops immediately and seek urgent medical attention if you notice any of the following:

  • Severe eye pain that does not settle quickly after instillation
  • Sudden or significant change in vision
  • Signs of a serious allergic reaction — swelling of the face, lips, or throat, difficulty breathing, or a widespread skin rash
  • Worsening redness, discharge, or swelling despite 2 days of treatment

What Should You Do If You Experience Side Effects of Brolene Eye Drops?

For mild side effects such as temporary stinging or brief blurred vision, no specific action is usually needed — these typically resolve on their own within minutes. If irritation persists or you develop a localised allergic reaction, stop using the drops and speak to a pharmacist or GP before continuing treatment.

You can report suspected side effects of any medicine in the UK directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. This helps regulators monitor the safety of medicines in real-world use.

Can Brolene Eye Drops Interact With Other Medicines?

There are no widely documented clinically significant drug interactions with Brolene eye drops at standard over-the-counter doses. However, if you are using other topical eye preparations — including prescription eye drops or ointments — you should allow at least 5 minutes between applications to avoid dilution or interference. The preservative benzalkonium chloride in Brolene can be absorbed by soft contact lens material, so always remove lenses before use and wait at least 15 minutes before reinserting them. If you are taking any systemic medicines and are unsure about compatibility, speak to your pharmacist before starting treatment.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

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Content last updated: 31 Mar 2025

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