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Brolene Eye Drop 10ml

Brolene Eye Drop 10ml

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  • ✔️ Treats minor bacterial conjunctivitis with propamidine isetionate 0.1%
  • ✔️ Reduces eye redness, discharge, and discomfort effectively
  • ✔️ Suitable for adults and children aged two years and over
  • ✔️ Available over the counter without a prescription in the UK
  • ✔️ Convenient 10ml bottle with 28-day use period after opening

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What Are Brolene Eye Drops and How Do They Help?

 

If your eyes are red, sticky, or uncomfortable, you are not alone. Minor eye infections are incredibly common in the UK, and Brolene eye drops have been a trusted over-the-counter option for decades. Each 10ml bottle contains propamidine isetionate 0.1%, a well-established antiseptic active ingredient used to treat minor bacterial eye infections, including conjunctivitis. You can browse our full range of treatments in our eye care collection if you are looking for additional support alongside this product.

Conjunctivitis — sometimes called "pink eye" — causes inflammation of the conjunctiva, the thin membrane covering the white of the eye and the inner eyelids. It can be bacterial, viral, or allergic in origin. Brolene eye drops are specifically indicated for the bacterial type, where the eye may produce a yellow or green discharge. They are available without a prescription, making them a convenient first-line option for adults and children aged 2 years and over.

 

How Do Brolene Eye Drops Work Against Infection?

 

Propamidine isetionate, the active ingredient in Brolene eye drops, belongs to a class of compounds called diamidines. It works as a topical antiseptic by targeting the outer membranes of bacterial cells. Here is a simplified breakdown of the mechanism:

  • Propamidine isetionate binds to the bacterial cell membrane.
  • It disrupts the integrity of the membrane, causing the cell contents to leak out.
  • This leads to bacterial cell death, reducing the infection load on the eye surface.
  • The antiseptic action helps clear discharge and reduce redness associated with minor infections.

Because it acts locally on the eye surface rather than being absorbed systemically, the risk of widespread side effects is low. That said, it is still important to use the drops correctly and for the right type of infection.

 

Who Is Brolene Eye Drops Suitable For?

 

Brolene eye drops are suitable for a fairly broad group of people, but they are not appropriate for everyone. They are designed for short-term use in otherwise healthy individuals experiencing a minor eye infection. You should consider this product if you:

  • Are an adult or child aged 2 years or over with symptoms of bacterial conjunctivitis.
  • Have a red, sticky, or discharging eye without any associated vision loss or severe pain.
  • Do not wear soft contact lenses (or are willing to remove them during treatment).
  • Have not already tried another antibiotic eye drop without success.

They are not suitable for people with known hypersensitivity to propamidine isetionate or any other ingredient in the formulation. If you are pregnant or breastfeeding, speak to your pharmacist or GP before using this product.

 

How Do Brolene Eye Drops Compare to Chloramphenicol Eye Drops?

 

Feature Brolene Eye Drops Chloramphenicol Eye Drops
Active ingredient Propamidine isetionate 0.1% Chloramphenicol 0.5%
Drug class Antiseptic (diamidine) Antibiotic (broad-spectrum)
Available OTC in UK Yes Yes (adults and children 2+)
Suitable for soft contact lens wearers No No

 

How Should You Store Brolene Eye Drops and Are They Clinically Suitable for You?

 

Store your bottle of Brolene eye drops below 25°C, away from direct sunlight and out of reach of children. Once opened, the drops should be discarded after 28 days — even if there is solution remaining — to reduce the risk of contamination and secondary infection. Never share eye drops with another person, as this can spread infection.

If you are managing multiple health concerns alongside an eye infection, it is worth knowing that Cured Pharmacy stocks a wide range of products. For example, if you also suffer from seasonal allergic conjunctivitis, our allergy and hay fever collection includes antihistamine eye drops and oral treatments that may complement your care. Always check with your pharmacist if you are unsure which product is right for your specific symptoms.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Brolene Eye Drops 10ml specifications
Treatment category Eye infections / Conjunctivitis
Active ingredient Propamidine isetionate 0.1%
Mechanism of action Antiseptic — disrupts bacterial cell membranes
Drug class Diamidine antiseptic
Preparation Sterile aqueous eye drops solution
Route of administration Ophthalmic (topical)
Pack size 10ml
UK classification General Sale List (GSL) / Pharmacy (P) medicine
Suitable for Adults and children aged 2 years and over
Effective against Minor bacterial eye infections, conjunctivitis

Specifications of Brolene Eye Drops 10ml

 

What Is Brolene Eye Drops and What Is It Used For?

 

Brolene Eye Drops 10ml is a topical ophthalmic antiseptic solution containing propamidine isetionate 0.1% as its active ingredient. It is used to treat minor bacterial eye infections, most commonly bacterial conjunctivitis. Conjunctivitis causes the white of the eye to appear red or pink, and the eye may feel gritty, itchy, or produce a sticky yellow or green discharge — particularly after sleep. Brolene eye drops work directly on the surface of the eye to reduce the bacterial load causing these symptoms.

This product is available over the counter in the UK without a prescription. It is intended for short-term use only. If your symptoms do not improve within 48 hours of starting treatment, or if they worsen at any point, you should stop using the drops and seek advice from a pharmacist or GP promptly.

 

What Do You Need to Know Before Using Brolene Eye Drops?

 

Before using Brolene eye drops, it is important to check whether this product is appropriate for you. Do not use this product if any of the following apply:

  • You are allergic to propamidine isetionate or any other ingredient in the formulation (including benzalkonium chloride).
  • You are under 2 years of age.
  • You wear soft contact lenses — benzalkonium chloride can be absorbed by soft lens material and cause irritation.
  • You have a severe eye infection, eye injury, or any condition affecting your vision.
  • You are pregnant or breastfeeding, unless advised by a healthcare professional.

Regarding drug interactions, no significant systemic interactions are established for topical ophthalmic propamidine isetionate. However, if you are using other eye drops or eye ointments at the same time, be aware of the following:

  • Allow at least 5 minutes between instilling different eye drops.
  • If using an eye ointment alongside drops, always apply the drops first and wait at least 5 minutes before applying the ointment.
  • Inform your pharmacist of all other eye preparations you are currently using.

 

How Should You Use Brolene Eye Drops?

 

Using eye drops correctly makes a real difference to how well they work. Follow these steps carefully each time you use Brolene eye drops:

  1. Wash your hands thoroughly with soap and water before handling the bottle.
  2. Tilt your head back slightly and look up towards the ceiling.
  3. Gently pull down your lower eyelid with one finger to create a small pocket.
  4. Hold the bottle above the eye (without touching the eye or eyelid with the tip) and squeeze one to two drops into the pocket.
  5. Close your eye gently and press lightly on the inner corner of the eye for about one minute — this helps prevent the drops draining away too quickly.
  6. Wipe away any excess liquid with a clean tissue.
  7. Repeat in the other eye if both are affected.
  8. Replace the cap immediately after use.
Indication Age Group Dose Frequency
Minor bacterial conjunctivitis Adults and children aged 2+ 1–2 drops per affected eye Up to 4 times daily
Minor bacterial eye infection Adults and children aged 2+ 1–2 drops per affected eye Up to 4 times daily

Do not use for longer than 2 days without reassessing your symptoms. If you are looking for additional first aid products to support eye hygiene during treatment, our first aid collection includes sterile eye wash and eye pads that can help keep the area clean.

 

What Are the Possible Side Effects of Brolene Eye Drops?

 

Like all medicines, Brolene eye drops can cause side effects, although not everyone experiences them. Most side effects are mild and localised to the eye.

Common side effects (may affect up to 1 in 10 people):

  • Temporary stinging or burning sensation immediately after instillation.
  • Mild eye irritation or discomfort.
  • Transient blurred vision immediately after use (avoid driving until vision clears).

Less common side effects (may affect fewer than 1 in 10 people):

  • Redness or increased watering of the eye.
  • Sensitivity to light (photophobia).
  • Localised allergic reaction, such as swelling of the eyelid or surrounding skin.

Stop using the drops and seek medical advice immediately if you experience severe eye pain, sudden changes in vision, significant swelling of the face or eyelids, or any sign of a serious allergic reaction (such as difficulty breathing or a widespread rash).

 

How Should You Store Brolene Eye Drops?

 

Correct storage helps maintain the safety and effectiveness of the product. Follow these storage instructions:

  • Store below 25°C in a cool, dry place.
  • Keep away from direct sunlight and heat sources.
  • Do not refrigerate unless specifically instructed to do so.
  • Keep the bottle tightly closed when not in use.
  • Discard the bottle 28 days after first opening, even if solution remains.
  • Keep out of the sight and reach of children.
  • Do not use after the expiry date printed on the label.
  • Do not share your eye drops with anyone else.

If you are managing other health conditions alongside an eye infection, remember that Cured Pharmacy offers a broad range of OTC treatments. Our ear, nose and throat collection may be useful if you are also experiencing cold-related symptoms that sometimes accompany conjunctivitis.

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Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Brolene eye drops online in the UK?

You can buy Brolene eye drops 10ml directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. They are available without a prescription as an over-the-counter medicine. Browse our full eye care collection for the complete range of eye infection treatments we stock.

How do Brolene eye drops work in the eye?

Brolene eye drops contain propamidine isetionate 0.1%, an antiseptic that works by binding to and disrupting the outer membranes of bacterial cells, causing them to break down and die. This reduces the bacterial population on the surface of the eye, clearing the infection. The action is localised to the eye surface, so systemic absorption is minimal.

How do I use Brolene eye drops step by step?

Wash your hands first, then tilt your head back and gently pull down your lower eyelid to create a small pocket. Squeeze one to two drops into the pocket without touching the eye with the bottle tip, then close your eye gently and press lightly on the inner corner for about one minute. Replace the cap immediately after use and repeat up to four times daily.

How long does it take for Brolene eye drops to work?

Most people begin to notice an improvement in symptoms such as redness, discharge, and discomfort within 48 hours of starting treatment. If your symptoms have not improved after two days, you should stop using the drops and consult a pharmacist or GP, as you may need a different treatment such as antibiotic eye drops. Do not continue using Brolene eye drops beyond this point without professional advice.

What is the correct dose of Brolene eye drops?

The standard dose for adults and children aged 2 years and over is one to two drops instilled into the affected eye or eyes, up to four times daily. Do not exceed this frequency unless directed by a healthcare professional. Always read the patient information leaflet supplied with the product before use.

Can I use Brolene eye drops with contact lenses?

No — you should not use Brolene eye drops while wearing soft contact lenses. The preservative benzalkonium chloride present in the formulation can be absorbed by soft lens material, which may cause eye irritation or damage to the lenses. Remove soft contact lenses before instilling the drops and wait at least 15 minutes before reinserting them. Hard (rigid gas-permeable) lenses should also be removed prior to use.

Who should not use Brolene eye drops?

Brolene eye drops are not suitable for children under 2 years of age, people with a known allergy to propamidine isetionate or benzalkonium chloride, or those wearing soft contact lenses. If you are pregnant, breastfeeding, or have a pre-existing eye condition such as glaucoma or a corneal injury, speak to your GP or pharmacist before using this product. It is not intended for the treatment of viral or allergic conjunctivitis.

What are the side effects of Brolene eye drops and how do I manage them?

The most common side effects are temporary stinging or burning immediately after instilling the drops, and mild eye irritation — both of which usually settle within a few minutes. Transient blurred vision can also occur, so avoid driving or operating machinery until your vision clears. If you experience severe pain, significant swelling, or any sudden change in vision, stop using the drops and seek medical advice immediately.

What happens if I miss a dose of Brolene eye drops?

If you forget to use your drops at the scheduled time, apply them as soon as you remember. However, if it is nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not double up doses to make up for a missed application, as this will not speed up recovery and may increase the risk of irritation.

How long can I use Brolene eye drops for?

Brolene eye drops are intended for short-term use only. You should reassess your symptoms after 48 hours of treatment. If there is no improvement, stop using the drops and consult a pharmacist or GP. Prolonged use beyond the recommended period is not advised without professional guidance, as it may mask a more serious underlying condition or contribute to local irritation.

Are Brolene eye drops safe during pregnancy?

There is limited clinical data on the use of propamidine isetionate during pregnancy. Because systemic absorption from topical eye drops is generally very low, the risk is considered minimal, but you should always consult your GP or midwife before using any medicine during pregnancy or while breastfeeding. They can advise on the safest option for your individual circumstances.

What are the alternatives to Brolene eye drops for conjunctivitis?

The main OTC alternative for bacterial conjunctivitis in the UK is chloramphenicol 0.5% eye drops, which is a broad-spectrum antibiotic and is often the first-line recommendation from pharmacists. For allergic conjunctivitis, antihistamine eye drops such as sodium cromoglicate may be more appropriate — you can explore options in our allergy and hay fever collection. Your pharmacist can help you choose the right product based on your specific symptoms.

Can children use Brolene eye drops?

Yes, Brolene eye drops can be used in children aged 2 years and over at the same dose as adults — one to two drops in the affected eye, up to four times daily. They should not be used in children under 2 years of age. If you are unsure whether your child's eye symptoms are bacterial in origin, speak to a pharmacist or GP before starting treatment, as viral and allergic causes require different management.

Do I need a prescription for Brolene eye drops in the UK?

No, Brolene eye drops are available over the counter in the UK without a prescription. They are classified as a Pharmacy (P) or General Sale List (GSL) medicine depending on the outlet. You can order them conveniently online from Cured Pharmacy and have them delivered to your door. Always read the patient information leaflet before use.

What is the latest guidance on treating bacterial conjunctivitis in the UK?

Current NHS guidance notes that most cases of bacterial conjunctivitis are self-limiting and may resolve without treatment within one to two weeks. However, topical antiseptic or antibiotic eye drops such as Brolene eye drops or chloramphenicol can help speed up recovery and reduce the risk of spreading infection to others. The NHS recommends good hygiene practices — such as washing hands frequently and avoiding sharing towels — as key measures to prevent spread.

How Should You Use Brolene Eye Drops?

Using Brolene eye drops correctly is essential to getting the most from your treatment and avoiding contamination. Always wash your hands before and after handling the bottle, and never allow the dropper tip to touch your eye, eyelid, or any other surface.

Follow these steps each time you apply the drops:

What Is the Correct Dose of Brolene Eye Drops?

The recommended dose for adults and children aged 2 years and over is one to two drops instilled into the affected eye or eyes, up to four times daily. Do not use more frequently than directed, as this will not speed up recovery and may increase the risk of irritation.

The table below summarises the dosing guidance by indication and age group:

When Is the Best Time to Use Brolene Eye Drops?

There is no single "best" time of day to use Brolene eye drops, but spacing your doses evenly throughout the day — for example, morning, midday, late afternoon, and evening — helps maintain a consistent antiseptic effect on the eye surface. Many people find it helpful to apply a dose after waking, as discharge tends to accumulate overnight and the eye may feel particularly sticky in the morning.

If you are also using other eye drops or ointments, always apply Brolene eye drops first and wait at least five minutes before using any other eye preparation. This prevents dilution of the active ingredient and ensures each product has time to be absorbed properly.

How Long Can You Use Brolene Eye Drops For?

Brolene eye drops are designed for short-term use only. You should review your symptoms after 48 hours of treatment. If there is a clear improvement, you may continue for up to the duration recommended on the packaging or by your pharmacist. If there is no improvement after two days, stop using the drops and seek advice from a pharmacist or GP, as you may require a different treatment.

Do not use Brolene eye drops for longer than recommended without professional guidance. Prolonged use may mask a more serious underlying eye condition or cause local irritation. Once opened, the bottle must be discarded after 28 days regardless of how much solution remains.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Brolene Eye Drops?

Most people who use Brolene eye drops tolerate them well, but some mild side effects can occur. These are usually temporary and resolve on their own within a few minutes of instilling the drops.

  • Temporary stinging or burning sensation immediately after application.
  • Mild eye irritation or discomfort.
  • Transient blurred vision immediately after instillation.
  • Increased watering of the eye.

If you experience blurred vision after using the drops, avoid driving or operating machinery until your vision has fully cleared. This effect is short-lived and not a cause for concern in most cases.

What Are the Less Common Side Effects of Brolene Eye Drops?

Less commonly, some people may experience more noticeable reactions, particularly if they are sensitive to any of the ingredients in the formulation. These side effects are not typical but are worth being aware of.

  • Redness or persistent irritation of the eye or surrounding skin.
  • Sensitivity to light (photophobia).
  • Swelling of the eyelid or the skin around the eye.
  • A feeling of something in the eye (foreign body sensation).

If any of these less common effects persist or worsen, stop using the drops and speak to your pharmacist or GP. They can assess whether the reaction is related to the drops or to the underlying infection itself.

What Are the Serious Side Effects of Brolene Eye Drops?

Serious side effects from Brolene eye drops are rare, but you should be aware of the warning signs that require prompt medical attention. Stop using the drops immediately and seek urgent medical advice if you notice any of the following:

  • Severe eye pain that does not settle quickly after instillation.
  • Sudden or significant changes in vision.
  • Marked swelling of the face, lips, or eyelids.
  • Difficulty breathing or signs of a serious allergic reaction (anaphylaxis).
  • Worsening redness or discharge despite two days of treatment.

A serious allergic reaction to propamidine isetionate is uncommon but possible. If you have ever had an allergic reaction to this ingredient before, do not use this product.

What Should You Do If You Experience Side Effects?

For mild side effects such as temporary stinging, no specific action is usually needed — simply wait a few minutes and the discomfort should pass. If you find the stinging particularly uncomfortable, try keeping the drops at room temperature before use, as cold drops can sometimes feel more irritating.

For any side effect that concerns you, or that does not resolve quickly, contact your pharmacist in the first instance. They can advise whether you should continue, switch to an alternative treatment, or see a GP. You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Brolene Eye Drops Interact With Other Medicines?

No significant systemic drug interactions have been established for topical propamidine isetionate, as absorption through the eye into the bloodstream is minimal. However, if you are using other eye drops or eye ointments at the same time, there are some practical points to bear in mind. Always apply Brolene eye drops first and wait at least five minutes before using any other eye preparation. If you are using an eye ointment, apply it after the drops and allow adequate time between applications. Inform your pharmacist of all eye preparations you are currently using so they can advise on the correct order and timing.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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