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Bazuka Sub-Zero Freeze Verruca & Wart Removal Treatment – 50ml

Bazuka Sub-Zero Freeze Verruca & Wart Removal Treatment – 50ml

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  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Freezes verrucas and warts to approximately -57°C
  • ✔️ Destroys abnormal HPV-infected skin cells on contact
  • ✔️ Works in as few as one to three fortnightly treatments
  • ✔️ Suitable for adults and children aged four years and over
  • ✔️ Mirrors clinical cryotherapy without a GP appointment

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Is Bazuka Sub-Zero the Right Verruca Freeze Treatment for You?

 

Verrucas and warts are incredibly common. In fact, the NHS estimates that most people will develop at least one wart at some point in their lives. They are caused by certain strains of the human papillomavirus (HPV), which triggers rapid, abnormal growth of skin cells. While they are harmless in most cases, they can be uncomfortable — particularly plantar warts on the soles of the feet — and many people simply want them gone. Verruca freeze treatment has become one of the most popular at-home options precisely because it mirrors the cryotherapy techniques used in clinical settings, without the need for a GP appointment. You can browse our full range of foot care products if you are looking for additional support alongside treatment.

Bazuka Sub-Zero Freeze Verruca & Wart Removal Treatment comes in a 50ml canister and is designed for straightforward home use. It is an over-the-counter medicine, meaning no prescription is needed. At £13.80, it offers a cost-effective alternative to repeated clinic visits.

 

How Does Bazuka Sub-Zero Work to Remove Warts and Verrucas?

 

The mechanism behind Bazuka Sub-Zero is cryotherapy — the controlled application of extreme cold to destroy unwanted tissue. The canister contains a cryogen mixture of dimethyl ether and propane (DMEP), which, when released through the foam applicator, reaches temperatures of approximately -57°C at the skin surface. Here is what happens during treatment:

  • The cryogen rapidly freezes the verruca or wart tissue on contact.
  • Ice crystals form within the abnormal cells, rupturing their membranes.
  • The destroyed tissue gradually separates from the surrounding healthy skin.
  • Healthy skin cells regenerate in the treated area over the following weeks.

This process is similar to the liquid nitrogen cryotherapy a GP or dermatologist might use, though the temperatures achieved are somewhat lower. It is a well-established approach for treating common warts and plantar verrucas.

 

Who Should Use Bazuka Sub-Zero Freeze Treatment?

 

This product is suitable for adults and children aged 4 years and over who have common warts or plantar verrucas. It is particularly useful for people who want a faster-acting alternative to daily salicylic acid treatments. That said, it is not appropriate for everyone.

  • Adults with common warts on hands or feet
  • Adults with plantar verrucas (warts on the sole of the foot)
  • Children aged 4 and above, under adult supervision
  • People who have not responded well to salicylic acid-based treatments

Do not use this product if you have diabetes, circulatory problems, or impaired sensation in your feet, as cryotherapy can cause complications in these groups. Always speak to your pharmacist or GP first if you are unsure.

 

How Does Bazuka Sub-Zero Compare to Other Wart Removal Options?

 

Feature Bazuka Sub-Zero (Cryotherapy) Salicylic Acid Gel (e.g. Bazuka Gel)
Mechanism Freezes and destroys tissue Chemically softens and removes tissue
Application frequency Every 2 weeks Daily
Typical treatment duration 1–4 treatments Up to 12 weeks
Suitable for children under 4 No Check individual product

 

How Should You Store Bazuka Sub-Zero and Is It Clinically Suitable for You?

 

Store the canister below 50°C, away from direct sunlight, heat sources, and open flames. The propellant is flammable, so never puncture or incinerate the canister — even when empty. Keep it out of reach of children. If you have any skin conditions affecting the treatment area, such as eczema or psoriasis, consult a healthcare professional before using this verruca freeze treatment. For related skin concerns, you may also find our skin care collection helpful.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Bazuka Sub-Zero Freeze Verruca & Wart Removal Treatment – 50ml specifications
Treatment category Wart and verruca removal
Mechanism of action Cryotherapy — freezes tissue using DMEP cryogen
Effective for Common warts and plantar verrucas
Suitable for Adults and children aged 4 years and over
Active ingredient Dimethyl ether and propane (DMEP)
Pack size 50ml
UK classification General Sale Medicine (GSL)
Preparation Pressurised cryotherapy spray
Route of administration Topical (cutaneous)

Specifications of Bazuka Sub-Zero Freeze Verruca & Wart Removal Treatment – 50ml

 

What Is Bazuka Sub-Zero and What Is It Used For?

 

Bazuka Sub-Zero Freeze Verruca & Wart Removal Treatment is an over-the-counter cryotherapy spray used to treat common warts and plantar verrucas. It works by applying a controlled burst of extreme cold directly to the affected skin, destroying the abnormal tissue caused by HPV infection. The NHS notes that warts and verrucas are very common and usually clear up on their own, but treatment can speed up resolution and reduce discomfort — particularly for plantar verrucas, which can be painful when walking.

 

What Do You Need to Know Before Using Bazuka Sub-Zero?

 

Before using this product, read the following contraindications and warnings carefully:

  • Do not use on the face, genitals, anal area, or mucous membranes.
  • Do not use on broken, infected, inflamed, or irritated skin.
  • Do not use if you have diabetes mellitus — reduced sensation and poor circulation increase the risk of complications.
  • Do not use if you have peripheral arterial disease or any condition affecting blood flow to the extremities.
  • Do not use on moles, birthmarks, or any lesion you are uncertain about — seek medical advice first.
  • Not suitable for children under 4 years of age.
  • Do not use near eyes or inhale the spray.
  • Flammable — keep away from flames and heat sources during and after application.

Regarding drug interactions, no significant interactions with systemic medicines have been identified for topical cryotherapy sprays of this type:

  • No known interactions with oral or topical medicines.
  • If you are using other topical treatments on the same area, consult your pharmacist before combining.

 

How Should You Use Bazuka Sub-Zero Correctly?

 

Always follow the instructions in the packaging carefully. The steps below reflect standard guidance for cryotherapy sprays of this type:

  1. Wash and dry the affected area thoroughly before treatment.
  2. Remove the cap and attach the foam applicator to the nozzle of the canister.
  3. Hold the canister upright and press the applicator firmly onto the centre of the wart or verruca.
  4. Apply steady pressure for the contact time specified on the packaging (typically around 20–40 seconds depending on lesion size).
  5. Release and allow the treated area to thaw naturally — do not rub or warm the skin artificially.
  6. Dispose of the used applicator safely after each treatment.
  7. Repeat after two weeks if the lesion has not fully resolved.
Indication Age Group Dose Frequency
Common warts Adults & children ≥4 years Single application per lesion Every 2 weeks, up to 4 treatments
Plantar verrucas Adults & children ≥4 years Single application per lesion Every 2 weeks, up to 4 treatments
Children under 4 Under 4 years Not suitable — do not use

If you are managing other foot concerns alongside your verruca, our athletes foot and fungal infections collection may also be relevant to you.

 

What Are the Possible Side Effects of Bazuka Sub-Zero?

 

Like all medicines, Bazuka Sub-Zero can cause side effects, although not everyone experiences them. The following lists cover what to look out for:

Common side effects:

  • Localised stinging or burning sensation during and immediately after application
  • Redness and mild swelling around the treated area
  • Blister formation at the treatment site (this is a normal response to cryotherapy)
  • Temporary skin discolouration (hypopigmentation or hyperpigmentation)

Less common side effects:

  • Prolonged or unusually large blistering
  • Infection of the treated site (signs include increasing pain, warmth, pus, or spreading redness)
  • Scarring, particularly with repeated applications to the same area
  • Nail damage if used near the nail bed

If a blister becomes very large, painful, or shows signs of infection, do not burst it yourself — seek advice from your pharmacist or GP. The NHS advises that you should see a GP if a wart or verruca bleeds, changes in appearance, or causes significant pain.

 

How Should You Store Bazuka Sub-Zero Safely?

 

  • Store below 50°C — do not leave in a hot car, on a sunny windowsill, or near radiators.
  • Keep away from open flames, sparks, and heat sources — the canister contains flammable propellant.
  • Do not puncture or incinerate the canister, even when empty.
  • Keep out of the reach and sight of children.
  • Do not use after the expiry date printed on the canister.
  • Store in the original packaging to protect from accidental discharge.

If you have any questions about safe storage or whether this product is right for you, speak to one of our pharmacists. You might also find it useful to explore our first aid collection for wound care products should you need to manage any blistering after treatment.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Bazuka Sub-Zero online in the UK?

You can buy Bazuka Sub-Zero Freeze Verruca & Wart Removal Treatment 50ml directly from Cured Pharmacy for £13.80, with no prescription required. It is a General Sale Medicine available over the counter. Ordering online means it can be delivered straight to your door without a GP visit.

How does Bazuka Sub-Zero work on verrucas and warts?

Bazuka Sub-Zero uses a cryogen mixture of dimethyl ether and propane (DMEP) to freeze the verruca or wart to approximately -57°C. This extreme cold destroys the abnormal skin cells by rupturing their membranes, causing the dead tissue to separate over the following days. Healthy skin then regenerates in its place.

How do I use Bazuka Sub-Zero step by step?

Clean and dry the affected area, then attach the foam applicator to the canister nozzle. Press the applicator firmly onto the centre of the wart or verruca for the contact time stated on the packaging, then allow the area to thaw naturally without rubbing. Repeat every two weeks if needed, for up to four treatments in total.

How many treatments of Bazuka Sub-Zero does it take to work?

Many warts and verrucas respond within one to three treatments, each spaced two weeks apart. Thicker or more established lesions may need up to four applications. If there is no visible improvement after four treatments, you should consult your pharmacist or GP for further advice.

Is Bazuka Sub-Zero safe for children?

Bazuka Sub-Zero is not suitable for children under 4 years of age. For children aged 4 and above, an adult must supervise and carry out the application — children should never use the canister themselves. If you are unsure whether it is appropriate for your child, speak to your pharmacist first.

What are the side effects of Bazuka Sub-Zero?

The most common side effects are localised stinging, redness, and blistering at the treatment site — these are expected responses to cryotherapy and usually resolve on their own. Less commonly, prolonged blistering or temporary skin discolouration may occur. If a blister becomes very large or shows signs of infection, seek advice from your pharmacist or GP.

Can I use Bazuka Sub-Zero on my face or genitals?

No — Bazuka Sub-Zero must not be applied to the face, genitals, anal area, or any mucous membranes. It should also be kept away from the eyes and must not be used on broken, infected, or inflamed skin. For warts in sensitive areas, please consult your GP for appropriate treatment options.

Can people with diabetes use Bazuka Sub-Zero?

No. People with diabetes should not use Bazuka Sub-Zero without first consulting their GP or diabetes care team. Diabetes can cause reduced sensation and poor circulation in the feet, which increases the risk of complications from cryotherapy, including delayed healing or undetected injury. The NHS advises people with diabetes to take particular care of their feet.

What is the difference between Bazuka Sub-Zero and Bazuka gel?

Bazuka Sub-Zero uses cryotherapy to freeze and destroy wart tissue in a single application every two weeks, whereas Bazuka gel contains salicylic acid and requires daily application over several weeks. Cryotherapy tends to work faster for many patients, but salicylic acid may be preferred for those who find the freezing sensation uncomfortable. Both are available without a prescription.

How long does it take for a verruca to fall off after using Bazuka Sub-Zero?

After a cryotherapy treatment, the frozen tissue typically forms a blister and then gradually separates from the surrounding skin over one to two weeks. The dead tissue may fall off on its own or can be gently removed once fully detached. You should wait the full two weeks before deciding whether a repeat treatment is needed.

What should I do if I accidentally spray Bazuka Sub-Zero on healthy skin?

If the cryogen contacts healthy skin, allow the area to warm naturally and do not rub it. Minor redness or stinging should resolve quickly. If you experience prolonged pain, significant blistering, or any other concerning reaction, seek advice from your pharmacist or, if severe, contact NHS 111.

Are there any alternatives to Bazuka Sub-Zero for verruca removal?

Yes — alternatives include salicylic acid-based treatments (applied daily), duct tape occlusion therapy, and professional cryotherapy with liquid nitrogen carried out by a GP or podiatrist. You can explore our foot care collection for other options. The NHS also notes that many warts and verrucas clear up without treatment, though this can take months or years.

How long can I use Bazuka Sub-Zero for?

The maximum recommended course is four treatments, each two weeks apart — so up to eight weeks in total. If the wart or verruca has not resolved after four applications, do not continue using the product and instead seek advice from your pharmacist or GP. Overuse increases the risk of skin damage and scarring.

Is Bazuka Sub-Zero the same as cryotherapy at the GP?

Bazuka Sub-Zero uses a similar principle to clinical cryotherapy but reaches lower temperatures than the liquid nitrogen used by GPs and dermatologists (approximately -57°C versus -196°C). This means it is effective for many common warts and verrucas but may be less effective for very thick or deeply embedded lesions. For persistent cases, professional treatment may be more appropriate.

What are the latest findings on at-home cryotherapy for warts?

Published evidence supports the use of DMEP-based cryotherapy sprays as an effective OTC option for common warts and verrucas, with studies showing clearance rates comparable to salicylic acid for many patients. The NHS recommends trying OTC treatments before seeking GP referral for wart removal. If you have concerns about a skin lesion, always seek professional assessment before self-treating. You can also explore our skin care collection for complementary products.

How Should You Use Bazuka Sub-Zero?

Using Bazuka Sub-Zero correctly is important both for effectiveness and for your safety. Always read the full instructions included in the packaging before your first treatment. The canister contains a flammable cryogen, so keep it away from flames and heat sources throughout the process.

What Is the Correct Dose of Bazuka Sub-Zero?

Each treatment consists of a single application per lesion per session. Do not apply more than once to the same lesion in a single session, as this increases the risk of skin damage. The table below summarises dosing by indication and age group.

When Is the Best Time to Use Bazuka Sub-Zero?

There is no specific time of day required for treatment, but many people find it easiest to apply after a bath or shower when the skin is clean and the surface of the verruca or wart is slightly softened. Avoid applying immediately before physical activity, as sweating or friction could irritate the treated area. Allow the skin to cool and dry fully before putting on socks or footwear after treatment.

How Long Can You Use Bazuka Sub-Zero For?

The maximum recommended course is four treatments, applied every two weeks — giving a total treatment period of up to eight weeks. If the wart or verruca has not resolved after four applications, stop using the product and consult your pharmacist or GP. Continuing beyond the recommended number of treatments does not improve outcomes and may cause unnecessary skin damage or scarring.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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The actual product sorted the problem straight away! In terms of delivery, took longer than tstated

What Are the Most Common Side Effects of Bazuka Sub-Zero?

Because Bazuka Sub-Zero works by freezing skin tissue, some degree of local reaction is expected and is actually a sign that the treatment is working. These common effects are generally mild and short-lived.

  • Stinging or burning sensation during and immediately after application
  • Redness and mild swelling around the treated area
  • Blister formation at the treatment site
  • Temporary tenderness when pressure is applied to the area

What Are the Less Common Side Effects of Bazuka Sub-Zero?

Less frequently, some people experience reactions that are more pronounced or take longer to resolve. These are not dangerous in most cases, but they do warrant attention.

  • Unusually large or persistent blistering
  • Temporary skin discolouration — either lighter (hypopigmentation) or darker (hyperpigmentation) than the surrounding skin
  • Nail damage if the product is applied close to the nail bed
  • Prolonged soreness lasting more than a week after treatment

What Are the Serious Side Effects of Bazuka Sub-Zero?

Serious side effects are uncommon but can occur, particularly if the product is used incorrectly or on unsuitable skin. If you notice any of the following, stop using the product and seek medical advice promptly.

  • Signs of skin infection at the treatment site — increasing pain, warmth, spreading redness, swelling, or pus
  • Scarring or permanent skin changes
  • Severe or spreading blistering beyond the treated area
  • Allergic reaction — rash, itching, or swelling away from the treatment site

What Should You Do If You Experience Side Effects of Bazuka Sub-Zero?

For mild reactions such as stinging and small blisters, no specific action is needed — allow the area to heal naturally and avoid bursting blisters, as this increases infection risk. The NHS advises that blisters should be left intact where possible. If a blister is very large, painful, or becomes infected, contact your pharmacist or GP. In the event of a severe allergic reaction, call 999 or go to your nearest A&E immediately.

Can Bazuka Sub-Zero Interact With Other Medicines?

No significant interactions between Bazuka Sub-Zero and systemic medicines have been identified. However, if you are already using another topical treatment on the same area — such as a salicylic acid gel or an antifungal cream — you should consult your pharmacist before combining products, as using multiple topical agents simultaneously may increase skin irritation. People with diabetes or circulatory conditions should always seek medical advice before using any cryotherapy product on their feet.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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