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Avamys Nasal Spray

Avamys Nasal Spray

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What Is Avamys Nasal Spray and How Does It Help?

 

If you've ever spent a spring morning sneezing uncontrollably or struggled to breathe through a blocked nose during pollen season, you'll know how disruptive allergic rhinitis can be. Avamys nasal spray is a clinically proven intranasal corticosteroid that targets the root cause of those symptoms — inflammation inside the nasal passages. It contains fluticasone furoate 27.5 micrograms per actuation and is licensed in the UK for the treatment of seasonal and perennial allergic rhinitis in adults and children aged 6 and over. Whether your symptoms are triggered by pollen, dust mites, or pet dander, Avamys works directly where it's needed most. You can browse our full range of allergy and hay fever treatments if you'd like to compare options before deciding.

Allergic rhinitis affects millions of people in the UK every year. Symptoms can range from a mildly irritating runny nose to severe nasal congestion that disrupts sleep, concentration, and daily life. Unlike oral antihistamines, which work systemically, Avamys acts locally in the nasal mucosa, meaning it delivers targeted relief with minimal systemic absorption.

 

How Does Avamys Nasal Spray Work in the Body?

 

Avamys works through a well-understood anti-inflammatory mechanism. When you're exposed to an allergen — pollen, for instance — your immune system triggers the release of inflammatory mediators such as histamine, prostaglandins, and leukotrienes. These chemicals cause the classic symptoms of allergic rhinitis. Fluticasone furoate, the active ingredient in Avamys, is a glucocorticoid that binds to glucocorticoid receptors in the nasal tissue and suppresses this inflammatory cascade.

  • Reduces the release of inflammatory chemicals in the nasal lining
  • Decreases swelling and congestion in the nasal passages
  • Relieves sneezing, itching, and a runny or blocked nose
  • Provides both early-phase and late-phase allergy response control

It's worth noting that Avamys doesn't work instantly. Most people notice an improvement within 8 hours of the first dose, but the full benefit typically builds over several days of regular use. Consistency is key — using it every day, even when symptoms feel manageable, gives you the best chance of sustained relief.

 

Who Should Use Avamys Nasal Spray?

 

Avamys is suitable for a broad range of patients, but it's particularly well-suited to those who haven't found adequate relief from oral antihistamines alone, or who prefer a treatment that works directly at the site of symptoms. It's licensed for both seasonal allergic rhinitis (such as hay fever) and perennial allergic rhinitis (year-round symptoms caused by indoor allergens).

It may be appropriate for you if:

  • You are an adult or a child aged 6 years or older
  • You experience nasal symptoms due to seasonal pollen or year-round allergens
  • Oral antihistamines haven't fully controlled your nasal congestion
  • You want a once-daily treatment that targets nasal inflammation directly

It is not suitable for children under 6, and you should speak to a doctor before using it if you have a nasal infection, have recently had nasal surgery, or are already using other corticosteroid medicines.

 

How Does Avamys Compare to Other Nasal Sprays?

 

Feature Avamys (Fluticasone Furoate) Flixonase (Fluticasone Propionate)
Active ingredient Fluticasone furoate 27.5mcg Fluticasone propionate 50mcg
Dosing frequency Once daily Once or twice daily
Minimum age 6 years 4 years (under medical supervision)
Receptor selectivity High glucocorticoid receptor affinity High glucocorticoid receptor affinity

 

Is Avamys Nasal Spray Safe for Long-Term Use?

 

For most people, Avamys nasal spray is considered safe for regular use during allergy season or throughout the year if you have perennial allergic rhinitis. Because fluticasone furoate has very low systemic bioavailability when administered intranasally, the risk of systemic corticosteroid side effects is low at recommended doses. That said, long-term use should be reviewed periodically by a healthcare professional, particularly in children, to monitor growth and nasal health.

If you're managing multiple allergy-related conditions — for example, using eye drops for allergic conjunctivitis alongside a nasal spray — it's worth exploring our ear, nose and throat treatments to find a coordinated approach. Always store Avamys below 30°C, keep it upright, and do not freeze it. Discard the bottle 2 months after first opening, even if product remains.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Avamys Nasal Spray specifications
Treatment category Allergic rhinitis / Hay fever
Mechanism of action Intranasal corticosteroid — reduces nasal inflammation via glucocorticoid receptor binding
Effective for Seasonal and perennial allergic rhinitis
Suitable for Adults and children aged 6 years and over
Active ingredient Fluticasone furoate 27.5 micrograms per actuation
Pack sizes 150 actuations per bottle
Strengths 27.5 micrograms per spray
UK classification Pharmacy (P) medicine
Drug class Corticosteroid (glucocorticoid)
Preparation Aqueous nasal suspension
Route of administration Intranasal

Specifications of Avamys Nasal Spray

 

What Is Avamys Nasal Spray and What Is It Used For?

 

Avamys nasal spray contains fluticasone furoate, a corticosteroid medicine used to treat the symptoms of allergic rhinitis. This includes both seasonal allergic rhinitis — commonly known as hay fever — and perennial allergic rhinitis, which causes symptoms throughout the year in response to allergens such as house dust mites, mould, or animal dander. It is licensed for use in adults and children aged 6 years and over. The spray works by reducing inflammation in the lining of the nose, helping to relieve sneezing, nasal congestion, a runny nose, and nasal itching.

 

What Do You Need to Know Before Using Avamys Nasal Spray?

 

Before using Avamys, it's important to check whether it is appropriate for you. Do not use this spray if any of the following apply:

  • You are allergic to fluticasone furoate or any other ingredient in the spray
  • You are under 6 years of age
  • You have an untreated nasal or sinus infection
  • You have recently had nasal surgery or a nasal injury that has not yet healed

Speak to your doctor or pharmacist before using Avamys if you:

  • Are already using other corticosteroid medicines (inhaled, oral, or topical)
  • Have tuberculosis (TB), either active or previously treated
  • Have glaucoma or cataracts, or a family history of these conditions
  • Are pregnant or breastfeeding
  • Are giving this medicine to a child — regular height monitoring is recommended

Drug interactions to be aware of:

  • Strong CYP3A4 inhibitors such as ritonavir (used in HIV treatment) and ketoconazole (an antifungal) may increase the amount of fluticasone furoate absorbed into the bloodstream, raising the risk of systemic corticosteroid effects
  • Avoid using other nasal corticosteroid sprays at the same time unless directed by a doctor

 

How Should You Use Avamys Nasal Spray Correctly?

 

Using Avamys correctly makes a real difference to how well it works. Before using for the first time, or if you haven't used it for more than 30 days, you'll need to prime the pump. Follow these steps each time you use it:

  1. Shake the bottle gently before each use
  2. Blow your nose gently to clear the nasal passages
  3. Remove the cap and hold the bottle upright with your thumb underneath and two fingers on top
  4. Tilt your head slightly forward and insert the nozzle into one nostril
  5. Aim the nozzle slightly away from the nasal septum (the central dividing wall)
  6. Press the pump firmly while breathing in gently through your nose
  7. Breathe out through your mouth
  8. Repeat in the other nostril
  9. Wipe the nozzle clean and replace the cap after use
Indication Age Group Dose Frequency
Allergic rhinitis (initial) Adults and adolescents (12+) 2 sprays per nostril (110mcg total) Once daily
Allergic rhinitis (maintenance) Adults and adolescents (12+) 1 spray per nostril (55mcg total) Once daily
Allergic rhinitis Children aged 6–11 years 1 spray per nostril (55mcg total) Once daily

 

What Are the Possible Side Effects of Avamys Nasal Spray?

 

Like all medicines, Avamys can cause side effects, although not everyone experiences them. Most side effects are mild and localised to the nose and throat. If you're also managing eye-related allergy symptoms, you might find our eye care range helpful alongside your nasal treatment.

Common side effects (affecting more than 1 in 100 people):

  • Nosebleeds (epistaxis) — the most frequently reported side effect
  • Nasal ulceration in rare cases with prolonged use
  • Headache

Less common side effects (affecting fewer than 1 in 100 people):

  • Nasal dryness or irritation
  • Unpleasant taste or smell
  • Throat irritation
  • Nasal septum perforation (very rare, with long-term use)
  • Raised intraocular pressure or glaucoma (rare, with prolonged use)
  • Hypersensitivity reactions including rash, urticaria, or swelling of the face and throat

Stop using Avamys and seek urgent medical attention if you develop signs of a severe allergic reaction, such as difficulty breathing, swelling of the lips, face, or throat, or a widespread skin rash.

 

How Should You Store Avamys Nasal Spray?

 

Correct storage helps maintain the effectiveness of the spray and keeps it safe to use. Follow these storage guidelines:

  • Store below 30°C — do not refrigerate or freeze
  • Keep the bottle upright at all times
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the label
  • Discard the bottle 2 months after first opening, even if product remains
  • Do not dispose of medicines via wastewater or household waste — return unused medicine to your pharmacist

If you're looking for additional support during allergy season, our cold and flu range includes products that can help manage overlapping symptoms such as congestion and sore throat.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Avamys nasal spray online in the UK?

You can buy Avamys nasal spray online from Cured Pharmacy, a GPhC-registered online pharmacy. It is available as a Pharmacy (P) medicine for adults and children aged 6 and over. Simply add it to your basket and complete a short eligibility check at checkout to ensure it's right for you.

How does Avamys nasal spray work in the body?

Avamys contains fluticasone furoate, a corticosteroid that binds to glucocorticoid receptors in the nasal lining and reduces the release of inflammatory chemicals triggered by allergens. This decreases swelling, congestion, and irritation in the nasal passages. It works locally with very low systemic absorption, which means it's unlikely to cause the side effects associated with oral steroids.

How do I use Avamys nasal spray step by step?

Shake the bottle gently, blow your nose, then tilt your head slightly forward. Insert the nozzle into one nostril, aim it away from the nasal septum, and press the pump while breathing in gently through your nose. Repeat in the other nostril, breathe out through your mouth, then wipe the nozzle and replace the cap.

What is the correct dose of Avamys nasal spray for adults?

The standard starting dose for adults and adolescents aged 12 and over is two sprays into each nostril once daily, giving a total of 110 micrograms of fluticasone furoate per day. Once your symptoms are well controlled, your pharmacist or doctor may suggest reducing to one spray per nostril once daily. Always follow the instructions provided with the product.

What is the correct dose of Avamys nasal spray for children?

Children aged 6 to 11 years should use one spray into each nostril once daily, giving a total of 55 micrograms per day. Avamys is not suitable for children under 6 years of age. If you're unsure whether Avamys is appropriate for your child, speak to your pharmacist or GP before use.

When is the best time to use Avamys nasal spray?

Avamys is a once-daily spray, so you can use it at any time of day that suits your routine — morning or evening. Using it at the same time each day helps you remember and ensures consistent levels of the medicine in your nasal tissue. During hay fever season, using it in the morning before going outdoors may help manage pollen exposure throughout the day.

How long does Avamys nasal spray take to work?

Some improvement in symptoms can be noticed within 8 hours of the first dose, but the full anti-inflammatory effect typically builds over several days of regular use. For seasonal allergic rhinitis, starting treatment a few days before your expected pollen exposure can help you get ahead of symptoms. Don't stop using it just because you feel better — consistent daily use gives the best results.

What are the most common side effects of Avamys nasal spray?

The most commonly reported side effect is nosebleeds (epistaxis), which affects more than 1 in 10 users. Headache and nasal dryness or irritation are also reported. These effects are usually mild and tend to settle with continued use — if nosebleeds are frequent or heavy, speak to your pharmacist or GP.

How do I manage nosebleeds caused by Avamys nasal spray?

Mild nosebleeds are a known and common side effect of intranasal corticosteroids including Avamys. To reduce the risk, make sure you're aiming the nozzle away from the nasal septum and not inserting it too deeply. If nosebleeds are persistent, heavy, or accompanied by other symptoms, stop using the spray and consult your GP or pharmacist promptly.

Who is eligible to use Avamys nasal spray?

Avamys nasal spray is suitable for adults and children aged 6 years and over who have been diagnosed with or are experiencing symptoms of seasonal or perennial allergic rhinitis. It is not suitable for children under 6, people with untreated nasal infections, or those who have recently had nasal surgery. If you have any underlying health conditions or take other medicines, check with your pharmacist first. You can also explore our full allergy and hay fever range to find the right treatment for you.

What happens if I miss a dose of Avamys nasal spray?

If you forget a dose, use it as soon as you remember — unless it's nearly time for your next scheduled dose, in which case simply skip the missed one. Never use a double dose to compensate. Missing the occasional dose is unlikely to cause problems, but regular use is important for sustained symptom control.

Can I use Avamys nasal spray during pregnancy?

If you are pregnant or planning to become pregnant, you should speak to your doctor or pharmacist before using Avamys nasal spray. While systemic absorption from intranasal corticosteroids is low, the safety of fluticasone furoate in pregnancy has not been fully established in clinical trials. Your healthcare professional can help you weigh the benefits and risks and suggest the most appropriate treatment.

What are the alternatives to Avamys nasal spray?

Other intranasal corticosteroids available in the UK include Beconase (beclometasone dipropionate), Flixonase (fluticasone propionate), and Nasonex (mometasone furoate). Antihistamine nasal sprays such as azelastine are another option, particularly for rapid symptom relief. Our ear, nose and throat range includes several alternatives your pharmacist can help you compare.

How long can you use Avamys nasal spray for?

Avamys can be used throughout the allergy season for seasonal allergic rhinitis, or on a longer-term basis for perennial allergic rhinitis. However, long-term use — particularly in children — should be reviewed periodically by a healthcare professional to monitor nasal health and, in children, growth. If your symptoms persist beyond 14 days without improvement, consult your GP.

Does Avamys nasal spray interact with other medicines?

Yes, certain medicines can interact with Avamys. Strong CYP3A4 inhibitors — including ritonavir (used in HIV treatment) and ketoconazole (an antifungal) — can increase the systemic absorption of fluticasone furoate, potentially raising the risk of corticosteroid-related side effects. Always tell your pharmacist or doctor about all medicines you are taking, including over-the-counter products and supplements.

How Should You Use Avamys Nasal Spray?

Using Avamys correctly is essential for getting the most out of your treatment. Before using the spray for the very first time — or if you haven't used it for more than 30 days — you'll need to prime the pump by pressing it several times until a fine mist appears. Follow these steps each time you use it:

Never insert the nozzle too deeply into the nostril, and avoid spraying directly onto the nasal septum, as this can increase the risk of nosebleeds and, with prolonged use, nasal ulceration.

What Is the Correct Dose of Avamys Nasal Spray?

The dose of Avamys depends on your age and how well your symptoms are controlled. Always use the lowest effective dose once your symptoms have improved. The table below summarises the recommended doses:

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

When Is the Best Time to Use Avamys Nasal Spray?

Avamys is a once-daily spray, so you can use it at any time of day that fits your routine — morning or evening. Consistency matters more than timing. Using it at the same time each day helps maintain steady levels of the medicine in your nasal tissue and makes it easier to remember. During hay fever season, many people find it helpful to use Avamys in the morning before heading outdoors, so the medicine is working before pollen exposure begins.

If you're starting treatment ahead of your usual allergy season, beginning a few days before symptoms typically appear can help you stay ahead of the inflammatory response rather than trying to catch up once symptoms are already established.

How Long Can You Use Avamys Nasal Spray For?

For seasonal allergic rhinitis, Avamys can be used throughout the relevant pollen season. For perennial allergic rhinitis — where symptoms occur year-round — longer-term use may be appropriate, but this should be reviewed periodically by your GP or pharmacist. In children, regular review is particularly important to monitor growth and nasal health. If your symptoms have not improved after 14 days of regular use, stop using the spray and consult your GP. Do not use Avamys for longer than recommended without medical review.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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Understanding Potential Side Effects

Like all medicines, Avamys Nasal Spray can have side effects, although not everyone will experience them. Most people tolerate this treatment well, and you can explore other ear, nose and throat treatments if you experience persistent issues.

The most commonly reported side effects include nosebleeds and nasal irritation, which usually occur during the first few weeks of treatment. These effects are generally mild and tend to decrease as your nasal passages adjust to the medication.

Known side effects may include:

  • Nosebleeds or blood-tinged mucus
  • Nasal dryness or irritation
  • Unpleasant taste or smell
  • Headache
  • Sore throat
  • Nasal burning or stinging sensation
  • Sneezing after application
  • Nasal congestion
  • Runny nose initially
  • Cough
  • Dizziness
  • Fatigue

If you experience these or any other side effects, speak to your doctor or pharmacist right away. For more information about reporting side effects please see the MHRA Yellow Card Scheme.

Frequently Asked Question

Most people start to feel relief within 8–24 hours, but the full effect is usually reached after 3–4 days of regular use.

Yes. Avamys is designed for daily use during allergy flare-ups or throughout allergy season.

Avamys can be used in children aged 6 years and older. It is not recommended for children under 6.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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How long does Avamys take to work?

Most people start to feel relief within 8–24 hours, but the full effect is usually reached after 3–4 days of regular use.

Can I use Avamys every day?

Yes. Avamys is designed for daily use during allergy flare-ups or throughout allergy season.

Is Avamys safe for children?

Avamys can be used in children aged 6 years and older. It is not recommended for children under 6.