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Avamys Nasal Spray

Avamys Nasal Spray

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What Is Avamys Nasal Spray and How Does It Help?

 

Avamys nasal spray is a corticosteroid nasal spray containing fluticasone furoate 27.5 mcg per actuation. It is used to relieve the symptoms of allergic rhinitis — that familiar combination of sneezing, nasal congestion, a runny nose, and itching that makes hay fever season so miserable. Whether your symptoms are seasonal (triggered by pollen) or perennial (caused by dust mites, pet dander, or mould), Avamys can help bring them under control. You can browse our full range of allergy and hay fever treatments if you want to compare your options before deciding.

Allergic rhinitis affects millions of people in the UK every year. It is not just an inconvenience — poorly controlled symptoms can disrupt sleep, affect concentration, and significantly reduce quality of life. Avamys is licensed for use in adults and children aged 6 years and over, making it a versatile option for households where more than one person suffers from allergy symptoms.

 

How Does Avamys Nasal Spray Work?

 

Fluticasone furoate, the active ingredient in Avamys, belongs to a class of medicines called corticosteroids. When sprayed into the nose, it acts locally on the nasal mucosa to reduce inflammation. Here is how the process works:

  • Allergens (such as pollen or dust) trigger an immune response in the nasal lining.
  • This causes the release of inflammatory chemicals — histamine, leukotrienes, and cytokines — that produce the classic allergy symptoms.
  • Fluticasone furoate binds to glucocorticoid receptors in nasal tissue and suppresses this inflammatory cascade.
  • The result is a reduction in swelling, mucus production, itching, and sneezing.
  • Because it acts locally, very little of the medicine is absorbed into the bloodstream, which means systemic side effects are uncommon at recommended doses.

It is worth noting that Avamys does not work instantly like a decongestant. It needs to be used regularly — ideally starting a few days before your allergy season begins — to build up its anti-inflammatory effect.

 

Who Should Use Avamys Nasal Spray?

 

Avamys is suitable for a wide range of people who experience nasal allergy symptoms. It is particularly useful if antihistamine tablets alone are not giving you enough relief, or if nasal congestion is your dominant symptom. Avamys may be appropriate for you if you:

  • Have seasonal allergic rhinitis (hay fever) triggered by grass, tree, or weed pollen.
  • Have perennial allergic rhinitis caused by year-round triggers such as house dust mites or pet hair.
  • Are aged 6 years or over (children aged 6–11 require a lower dose).
  • Have not found adequate relief from oral antihistamines alone.

It is not suitable for everyone. People with nasal infections, those who have recently had nasal surgery, or those already using other corticosteroid medicines should speak to a doctor or pharmacist before starting Avamys. If you also experience eye symptoms alongside your nasal allergy, our eye care range includes antihistamine eye drops that can complement nasal treatment.

 

How Does Avamys Nasal Spray Compare to Other Nasal Sprays?

 

Feature Avamys (Fluticasone Furoate) Flixonase (Fluticasone Propionate)
Active ingredient Fluticasone furoate 27.5 mcg Fluticasone propionate 50 mcg
Minimum age 6 years 4 years
Dosing frequency Once daily Once or twice daily
Onset of action Within 8 hours (some patients) Within 12 hours (some patients)

 

Is Avamys Nasal Spray Safe for Long-Term Use?

 

When used at the recommended dose, Avamys nasal spray is generally considered safe for ongoing use during allergy seasons. Because fluticasone furoate has a high affinity for glucocorticoid receptors but low systemic bioavailability (less than 0.5% absorbed), the risk of systemic corticosteroid effects is low. That said, long-term use should be reviewed periodically by a healthcare professional, particularly in children, to monitor growth and nasal health.

If you are using Avamys alongside other medicines — especially antifungals like ketoconazole or HIV medicines like ritonavir — speak to your pharmacist first, as these can increase the amount of fluticasone in your bloodstream. You might also find it helpful to explore our ear, nose, and throat range for complementary products that support nasal health during allergy season.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Avamys Nasal Spray specifications
Treatment category Allergic rhinitis / Hay fever
Active ingredient Fluticasone furoate 27.5 mcg per actuation
Mechanism of action Intranasal corticosteroid — reduces nasal inflammation
Suitable for Adults and children aged 6 years and over
Pack sizes 150 actuations per bottle
Strengths 27.5 mcg per spray
UK classification P (Pharmacy medicine)
Drug class Corticosteroid
Preparation Aqueous nasal suspension
Route of administration Intranasal

Specifications of Avamys Nasal Spray

 

What Is Avamys Nasal Spray and What Is It Used For?

 

Avamys nasal spray contains fluticasone furoate, an intranasal corticosteroid used to treat the symptoms of allergic rhinitis in adults and children aged 6 years and over. Allergic rhinitis occurs when the immune system overreacts to airborne allergens, causing inflammation of the nasal lining. Symptoms include sneezing, nasal congestion, a runny nose, and nasal itching. Avamys is effective for both seasonal allergic rhinitis (such as hay fever caused by pollen) and perennial allergic rhinitis (caused by year-round allergens like house dust mites or animal dander). It is available as a pharmacy (P) medicine in the UK, meaning you can purchase it without a prescription.

 

What Do You Need to Know Before Using Avamys Nasal Spray?

 

Before using Avamys, it is important to check whether it is appropriate for you. Do not use Avamys if any of the following apply:

  • You are allergic to fluticasone furoate or any other ingredient in the spray (including benzalkonium chloride, polysorbate 80, or microcrystalline cellulose).
  • You have an active nasal or sinus infection that has not been treated.
  • You have recently had nasal surgery or a nasal injury — wait until fully healed before using.
  • Your child is under 6 years of age.

Talk to your doctor or pharmacist before using Avamys if you:

  • Are already using other corticosteroid medicines (inhaled, oral, or topical), as combined use may increase the risk of systemic effects.
  • Have tuberculosis (TB), or any other untreated infection.
  • Have problems with your vision, or a family history of glaucoma or cataracts.
  • Are pregnant or breastfeeding — seek medical advice before use.

Drug interactions to be aware of:

  • Ritonavir and other HIV protease inhibitors — may significantly increase fluticasone blood levels.
  • Ketoconazole and other strong CYP3A4 inhibitors — may increase systemic exposure to fluticasone furoate.
  • Other corticosteroids — concurrent use increases the risk of adrenal suppression.

 

How Should You Use Avamys Nasal Spray?

 

Always use Avamys exactly as directed on the label or as advised by your pharmacist. Before using for the first time, prime the pump by pressing it down and releasing it six times until a fine mist appears. If the spray has not been used for five or more days, re-prime with one spray. Follow these steps each time you use it:

  1. Blow your nose gently to clear the nasal passages.
  2. Shake the bottle gently.
  3. Remove the cap and hold the bottle upright.
  4. Tilt your head slightly forward.
  5. Insert the nozzle into one nostril, angling it slightly away from the nasal septum (the central dividing wall).
  6. Press the pump down firmly while breathing in gently through your nose.
  7. Breathe out through your mouth.
  8. Repeat in the other nostril.
  9. Wipe the nozzle clean and replace the cap after use.
Indication Age Group Dose Frequency
Allergic rhinitis Adults & adolescents (12+) 2 sprays per nostril (110 mcg total) Once daily
Allergic rhinitis Children aged 6–11 1 spray per nostril (55 mcg total) Once daily

Once symptoms are well controlled, your doctor may suggest reducing to 1 spray per nostril once daily in adults. Do not exceed the recommended dose. If symptoms do not improve after 14 days of use, speak to your pharmacist or GP.

 

What Are the Possible Side Effects of Avamys Nasal Spray?

 

Like all medicines, Avamys can cause side effects, although not everyone experiences them. Most side effects are mild and affect the nose or throat. If you are concerned about any side effect, speak to your pharmacist or GP.

Common side effects (may affect up to 1 in 10 people):

  • Nosebleeds (epistaxis)
  • Nasal ulceration
  • Headache
  • Nasal irritation or discomfort

Less common side effects (may affect up to 1 in 100 people):

  • Nasal septum perforation (rare but serious — stop use and seek medical advice)
  • Blurred vision or other visual disturbances
  • Raised intraocular pressure (glaucoma)
  • Cataracts with prolonged use
  • Allergic reactions including rash, swelling of the face, or difficulty breathing (seek emergency help immediately)

If you experience a severe allergic reaction, stop using Avamys and seek emergency medical attention. You can also find information on managing related conditions in our cold and flu range, which includes products to support nasal comfort during illness.

 

How Should You Store Avamys Nasal Spray?

 

Correct storage helps maintain the effectiveness of Avamys throughout its shelf life. Follow these storage instructions:

  • Store below 30°C.
  • Keep the bottle upright at all times.
  • Do not freeze or refrigerate.
  • Keep out of the sight and reach of children.
  • Do not use after the expiry date printed on the label.
  • Discard the bottle after 150 actuations, even if it appears to still contain liquid.
  • Do not dispose of medicines via wastewater or household waste — return unused medicines to your pharmacy for safe disposal.

If you are managing multiple health conditions and need to keep track of several medicines, our electrical health and diagnostic range includes tools that can help you monitor your health at home.

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Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Avamys nasal spray online in the UK?

You can buy Avamys nasal spray from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £11.99 with fast UK delivery. It is available as a pharmacy (P) medicine, meaning no prescription is needed for adults and children aged 6 and over. Simply add it to your basket and complete a short health questionnaire to confirm suitability.

How does Avamys nasal spray work in the body?

Avamys contains fluticasone furoate, a corticosteroid that works by binding to glucocorticoid receptors in the nasal lining and reducing the release of inflammatory chemicals triggered by allergens. This decreases swelling, mucus production, itching, and sneezing. Because it acts locally in the nose, very little is absorbed into the bloodstream, making systemic side effects uncommon at recommended doses.

How do I use Avamys nasal spray step by step?

Blow your nose gently, shake the bottle, and tilt your head slightly forward. Insert the nozzle into one nostril pointing away from the nasal septum, then press the pump while breathing in gently through your nose. Repeat in the other nostril, wipe the nozzle, and replace the cap — it takes less than a minute once you get used to it.

What is the correct dose of Avamys nasal spray for adults?

Adults and adolescents aged 12 and over should use 2 sprays into each nostril once daily, giving a total daily dose of 110 mcg of fluticasone furoate. Once symptoms are well controlled, a doctor may reduce this to 1 spray per nostril once daily. Never exceed the recommended dose without medical advice.

What is the correct dose of Avamys nasal spray for children?

Children aged 6 to 11 years should use 1 spray into each nostril once daily, giving a total daily dose of 55 mcg. Avamys is not recommended for children under 6 years of age. Always supervise children when using nasal sprays and consult your pharmacist if you are unsure about the correct technique.

How long does Avamys nasal spray take to work?

Some people notice an improvement in nasal symptoms within 8 hours of their first dose, though it can take several days of consistent use to experience the full anti-inflammatory benefit. For seasonal allergic rhinitis, it is a good idea to start using Avamys a few days before your allergy season begins. Regular daily use gives the best results — skipping doses can reduce its effectiveness.

What are the most common side effects of Avamys nasal spray?

The most frequently reported side effect is nosebleeds (epistaxis), which affects up to 1 in 10 users. Nasal irritation, headache, and nasal ulceration are also common. Most of these effects are mild and tend to settle with continued use, but if nosebleeds are frequent or severe, speak to your pharmacist or GP.

Who should not use Avamys nasal spray?

Avamys should not be used by anyone allergic to fluticasone furoate or any of its excipients, or by children under 6 years of age. People with active nasal infections, recent nasal surgery, or those already taking strong CYP3A4 inhibitors such as ritonavir or ketoconazole should seek medical advice before use. If you are pregnant or breastfeeding, consult your doctor before starting treatment.

Can I use Avamys nasal spray during pregnancy?

There is limited data on the use of fluticasone furoate during pregnancy, so it is important to speak to your GP or midwife before using Avamys if you are pregnant or planning to become pregnant. The general principle is to use the lowest effective dose for the shortest time necessary. Your doctor can help you weigh up the benefits and risks for your individual situation.

What happens if I miss a dose of Avamys nasal spray?

If you forget a dose, simply use it as soon as you remember — unless it is almost time for your next dose, in which case skip the missed one and carry on as normal. Do not use a double dose to make up for a missed one. Consistent daily use is important for maintaining the anti-inflammatory effect, so try to use it at the same time each day.

Can Avamys nasal spray be used alongside antihistamine tablets?

Yes, Avamys can generally be used alongside oral antihistamines such as cetirizine or loratadine, and this combination is often recommended for people with moderate to severe allergic rhinitis. Using both together can provide broader symptom relief — the antihistamine targets histamine-driven symptoms like itching and sneezing, while Avamys addresses nasal inflammation and congestion. Always check with your pharmacist if you are unsure about combining treatments. You can explore our full allergy and hay fever range for suitable antihistamine options.

What are the alternatives to Avamys nasal spray?

Other intranasal corticosteroids available in the UK include Beconase (beclometasone dipropionate), Flixonase (fluticasone propionate), and Nasacort (triamcinolone acetonide). Antihistamine nasal sprays such as azelastine are another option, particularly for rapid symptom relief. Your pharmacist can help you choose the most appropriate treatment based on your symptoms, age, and medical history.

How long can you use Avamys nasal spray for?

Avamys can be used throughout the allergy season, which for hay fever sufferers typically runs from March to September in the UK. If you have perennial allergic rhinitis, longer-term use may be appropriate, but this should be reviewed periodically by a healthcare professional. If symptoms do not improve after 14 days of use, or if they worsen at any point, seek advice from your GP or pharmacist.

Does Avamys nasal spray interact with other medicines?

The most clinically significant interactions are with strong CYP3A4 inhibitors — medicines such as ritonavir (used for HIV) and ketoconazole (an antifungal) — which can increase the amount of fluticasone furoate in your bloodstream and raise the risk of systemic corticosteroid effects. Using Avamys alongside other corticosteroid medicines (inhaled, oral, or topical) may also increase this risk. Always tell your pharmacist about all medicines you are taking, including herbal remedies and supplements.

What are the latest findings on fluticasone furoate nasal sprays?

Fluticasone furoate has been shown in clinical studies to have a high receptor binding affinity and prolonged duration of action compared to some other intranasal corticosteroids, supporting once-daily dosing. Research published in peer-reviewed journals has confirmed its efficacy in reducing both nasal and ocular symptoms of allergic rhinitis. The NHS and NICE continue to recommend intranasal corticosteroids as first-line treatment for allergic rhinitis in adults and children. For broader nasal and throat health support, explore our ear, nose, and throat range.

How Should You Use Avamys Nasal Spray?

Before using Avamys for the first time, you need to prime the pump. Press the nozzle down and release it six times until a fine mist appears. If the spray has not been used for five or more days, re-prime with one spray before use. Follow these steps each time:

Clean the nozzle regularly by removing it and rinsing it under warm water, then allowing it to dry before replacing. Never try to unblock the nozzle with a pin or sharp object.

What Is the Correct Dose of Avamys Nasal Spray?

Always use the dose recommended for your age group. Using more than the recommended dose will not improve your symptoms faster and may increase the risk of side effects. The table below summarises the standard dosing guidance:

Once symptoms are well controlled in adults, your doctor may advise reducing to 1 spray per nostril once daily as a maintenance dose. Avamys is not recommended for children under 6 years of age.

When Is the Best Time to Use Avamys Nasal Spray?

Avamys is designed to be used once daily, and the best time is in the morning — ideally at the same time each day. Using it consistently at the same time helps maintain a steady anti-inflammatory effect throughout the day, which is when pollen counts and allergen exposure tend to be highest. If you are using Avamys for seasonal hay fever, starting treatment a few days before your allergy season begins can help prevent symptoms from taking hold rather than simply treating them once they have already started.

How Long Can You Use Avamys Nasal Spray For?

For seasonal allergic rhinitis, Avamys can be used throughout the relevant pollen season, which in the UK typically runs from late February through to September depending on the allergen. For perennial allergic rhinitis, longer-term use may be appropriate under the guidance of a healthcare professional. If your symptoms have not improved after 14 days of regular use, or if they worsen at any point, stop using Avamys and speak to your GP or pharmacist. Periodic review is recommended for anyone using intranasal corticosteroids on a long-term basis, particularly children, to monitor nasal health and growth.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

How Should You Use Avamys Nasal Spray?

Before using Avamys for the first time, you need to prime the pump. Press the nozzle down and release it six times until a fine mist appears. If the spray has not been used for five or more days, re-prime with one spray before use. Follow these steps each time:

Clean the nozzle regularly by removing it and rinsing it under warm water, then allowing it to dry before replacing. Never try to unblock the nozzle with a pin or sharp object.

What Is the Correct Dose of Avamys Nasal Spray?

Always use the dose recommended for your age group. Using more than the recommended dose will not improve your symptoms faster and may increase the risk of side effects. The table below summarises the standard dosing guidance:

Once symptoms are well controlled in adults, your doctor may advise reducing to 1 spray per nostril once daily as a maintenance dose. Avamys is not recommended for children under 6 years of age.

When Is the Best Time to Use Avamys Nasal Spray?

Avamys is designed to be used once daily, and the best time is in the morning — ideally at the same time each day. Using it consistently at the same time helps maintain a steady anti-inflammatory effect throughout the day, which is when pollen counts and allergen exposure tend to be highest. If you are using Avamys for seasonal hay fever, starting treatment a few days before your allergy season begins can help prevent symptoms from taking hold rather than simply treating them once they have already started.

How Long Can You Use Avamys Nasal Spray For?

For seasonal allergic rhinitis, Avamys can be used throughout the relevant pollen season, which in the UK typically runs from late February through to September depending on the allergen. For perennial allergic rhinitis, longer-term use may be appropriate under the guidance of a healthcare professional. If your symptoms have not improved after 14 days of regular use, or if they worsen at any point, stop using Avamys and speak to your GP or pharmacist. Periodic review is recommended for anyone using intranasal corticosteroids on a long-term basis, particularly children, to monitor nasal health and growth.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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Understanding Potential Side Effects

Like all medicines, Avamys Nasal Spray can have side effects, although not everyone will experience them. Most people tolerate this treatment well, and you can explore other ear, nose and throat treatments if you experience persistent issues.

The most commonly reported side effects include nosebleeds and nasal irritation, which usually occur during the first few weeks of treatment. These effects are generally mild and tend to decrease as your nasal passages adjust to the medication.

Known side effects may include:

  • Nosebleeds or blood-tinged mucus
  • Nasal dryness or irritation
  • Unpleasant taste or smell
  • Headache
  • Sore throat
  • Nasal burning or stinging sensation
  • Sneezing after application
  • Nasal congestion
  • Runny nose initially
  • Cough
  • Dizziness
  • Fatigue

If you experience these or any other side effects, speak to your doctor or pharmacist right away. For more information about reporting side effects please see the MHRA Yellow Card Scheme.

Frequently Asked Question

Most people start to feel relief within 8–24 hours, but the full effect is usually reached after 3–4 days of regular use.

Yes. Avamys is designed for daily use during allergy flare-ups or throughout allergy season.

Avamys can be used in children aged 6 years and older. It is not recommended for children under 6.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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How long does Avamys take to work?

Most people start to feel relief within 8–24 hours, but the full effect is usually reached after 3–4 days of regular use.

Can I use Avamys every day?

Yes. Avamys is designed for daily use during allergy flare-ups or throughout allergy season.

Is Avamys safe for children?

Avamys can be used in children aged 6 years and older. It is not recommended for children under 6.