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Artelac Rebalance Eye Drops 0.32% - 10ml

Artelac Rebalance Eye Drops 0.32% - 10ml

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  • ✔️ Soothes dry, gritty eyes with 0.32% hyaluronic acid
  • ✔️ Vitamin B12 protects corneal cells from oxidative damage
  • ✔️ Preservative-free formula ideal for sensitive or frequent use
  • ✔️ Stabilises the tear film for lasting ocular comfort
  • ✔️ Suitable for adults with chronic dry eye syndrome

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What Are Artelac Rebalance Eye Drops and How Do They Help Dry Eyes?

 

Dry, gritty, or tired eyes are something millions of people in the UK deal with every day — whether from screen use, air conditioning, ageing, or environmental factors. Artelac Rebalance eye drops offer a preservative-free solution that combines two active ingredients to help restore comfort and protect the ocular surface. Available over the counter without a prescription, this 10ml bottle is a practical option for anyone managing mild to moderate dry eye symptoms. You can browse the full range of products in our eye care collection if you're looking for additional support.

Each millilitre of Artelac Rebalance contains 3.2 mg of sodium hyaluronate (hyaluronic acid) alongside cyanocobalamin, the active form of vitamin B12. This combination is what sets it apart from many standard lubricating drops on the market. The formulation is designed to work with your natural tear film rather than simply masking dryness temporarily.

 

How Do Artelac Rebalance Eye Drops Work to Relieve Dry Eyes?

 

The mechanism behind these drops is straightforward but clinically meaningful. Hyaluronic acid is a naturally occurring substance found in the body, including in the vitreous humour of the eye. It has exceptional water-retaining properties, which means it helps keep the ocular surface hydrated for longer than many simpler lubricants. Vitamin B12 (cyanocobalamin) adds an antioxidant dimension — it helps neutralise oxidative stress on the corneal epithelium, which can be a contributing factor in chronic dry eye disease.

  • Hyaluronic acid forms a stable, viscoelastic layer over the cornea, reducing friction with each blink
  • Vitamin B12 supports corneal nerve health and reduces oxidative damage to surface cells
  • The preservative-free formula minimises the risk of further irritation, especially with frequent use
  • The drops stabilise the tear film, helping to prevent rapid evaporation between blinks

 

Who Should Use Artelac Rebalance Eye Drops?

 

These drops are suitable for adults experiencing the symptoms of dry eye syndrome, including burning, stinging, grittiness, or a feeling of something in the eye. They're particularly well-suited to people who spend long hours in front of screens, wear contact lenses (though lenses must be removed before use), or live and work in dry or air-conditioned environments. If you've tried basic lubricating drops without much relief, the dual-action formula here may offer a more targeted approach.

  • Adults with mild to moderate dry eye syndrome
  • People with screen fatigue or digital eye strain
  • Those who are sensitive to preservatives in standard eye drops
  • Individuals whose dry eye symptoms are linked to oxidative stress or nerve-related discomfort

 

How Do Artelac Rebalance Eye Drops Compare to Other Lubricating Eye Drops?

 

Feature Artelac Rebalance 0.32% Standard Hyaluronic Acid Drops (e.g. 0.1%)
Hyaluronic acid concentration 0.32% (higher viscosity) 0.1% (lower viscosity)
Contains vitamin B12 Yes — antioxidant support No
Preservative-free Yes Varies by brand
Suitable for sensitive eyes Yes Not always

 

Is Artelac Rebalance Suitable for Long-Term Use and How Should It Be Stored?

 

Because artelac rebalance eye drops are preservative-free, they are generally considered appropriate for long-term daily use — a key advantage for people with chronic dry eye conditions. However, the bottle must be discarded 90 days after first opening, even if solution remains. Store the bottle below 25°C and do not refrigerate. Keep it out of direct sunlight and away from children. If you're also managing other eye conditions or taking systemic medications, it's worth checking with your pharmacist before starting any new eye drop regimen. You might also find it helpful to explore our allergy and hay fever range if seasonal allergies are contributing to your eye discomfort.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Artelac Rebalance Eye Drops 0.32% - 10ml specifications
Treatment category Dry eye / ocular lubricant
Active ingredient Sodium hyaluronate 0.32%, Cyanocobalamin (Vitamin B12)
Mechanism of action Lubricates and stabilises the tear film; antioxidant protection via vitamin B12
Suitable for Adults with dry eye syndrome
Pack size 10ml
Strength 0.32% sodium hyaluronate
UK classification General Sale / OTC
Preparation Sterile ophthalmic solution
Route of administration Topical ocular (eye drops)

Specifications of Artelac Rebalance Eye Drops 0.32% - 10ml

 

What Is Artelac Rebalance and What Is It Used For?

 

Artelac Rebalance Eye Drops 0.32% is a sterile, preservative-free ophthalmic solution used to relieve the symptoms of dry eye syndrome. Dry eye — also known as keratoconjunctivitis sicca — occurs when the eyes do not produce enough tears, or when the tears evaporate too quickly. Symptoms include burning, stinging, grittiness, redness, and blurred vision. The NHS recognises dry eye as a common condition that can significantly affect quality of life, particularly in older adults and those who use digital screens for extended periods.

The drops contain two active components: sodium hyaluronate at 0.32% concentration, which provides sustained lubrication, and cyanocobalamin (vitamin B12), which offers antioxidant support to the corneal surface. Together, they help to restore a stable, comfortable tear film. Artelac Rebalance eye drops are intended for use in adults and are available without a prescription.

 

What Do You Need to Know Before Using Artelac Rebalance Eye Drops?

 

Before using these drops, read the following contraindications and warnings carefully:

  • Do not use if you are allergic to sodium hyaluronate, cyanocobalamin, or any other ingredient in the formulation
  • Remove soft contact lenses before instilling the drops; wait at least 15 minutes before reinserting
  • Do not use if the bottle seal is broken before first use
  • Not recommended for use in children unless directed by a doctor
  • If you have an eye infection, eye injury, or have recently had eye surgery, consult your doctor before use
  • Discard the bottle 90 days after opening, even if solution remains

Regarding drug interactions, no clinically significant interactions with systemic medicines have been reported for topically applied sodium hyaluronate or cyanocobalamin. However:

  • If you are using other eye drops or eye ointments, allow at least 5 minutes between applications
  • Apply eye ointments last if using alongside these drops
  • Always inform your pharmacist of all medicines you are currently using

 

How Should You Use Artelac Rebalance Eye Drops?

 

Follow these steps carefully each time you use the drops to ensure safe and effective application:

  1. Wash your hands thoroughly with soap and water before handling the bottle
  2. Remove contact lenses if worn
  3. Tilt your head back slightly and look upward
  4. Gently pull down your lower eyelid to create a small pocket
  5. Hold the bottle above the eye and instil one to two drops into the pocket
  6. Close your eye gently and blink a few times to spread the solution
  7. Avoid touching the dropper tip to your eye, eyelid, or any surface to prevent contamination
  8. Replace the cap immediately after use
Indication Age Group Dose Frequency
Dry eye syndrome Adults 1–2 drops per affected eye As needed, typically 3–5 times daily
Dry eye syndrome Children Only on medical advice As directed by a doctor

 

What Are the Possible Side Effects of Artelac Rebalance Eye Drops?

 

Like all medicines, Artelac Rebalance Eye Drops can cause side effects, although not everyone experiences them. Most side effects are mild and resolve quickly after instillation. If you experience any persistent or severe symptoms, stop using the drops and seek medical advice promptly. You can find further guidance on managing eye conditions through the NHS website.

Common side effects (may affect up to 1 in 10 people):

  • Temporary blurred vision immediately after instillation
  • Mild stinging or burning sensation in the eye
  • Watery eyes shortly after use

Less common side effects (may affect up to 1 in 100 people):

  • Redness of the eye (conjunctival hyperaemia)
  • Sensation of a foreign body in the eye
  • Eye discharge or crusting around the eyelid
  • Headache

Stop use and consult a healthcare professional immediately if you notice sudden vision changes, severe eye pain, or signs of an allergic reaction such as swelling of the eyelids or face. If you're also experiencing nasal or sinus symptoms alongside eye irritation, our ear, nose and throat range may offer complementary support.

 

How Should You Store Artelac Rebalance Eye Drops?

 

  • Store below 25°C in a dry place away from direct sunlight
  • Do not refrigerate or freeze
  • Keep the bottle tightly closed when not in use
  • Keep out of the sight and reach of children
  • Discard 90 days after first opening — write the opening date on the bottle
  • Do not use after the expiry date printed on the label
  • Do not dispose of medicines via wastewater or household waste — return unused medicines to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Artelac Rebalance Eye Drops online in the UK?

You can buy Artelac Rebalance Eye Drops 0.32% 10ml directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £6.39. No prescription is needed as it is an over-the-counter product. Browse our full eye care collection for a wider range of dry eye and ocular health products.

How do Artelac Rebalance Eye Drops work in the eye?

The drops work through a dual mechanism: sodium hyaluronate at 0.32% forms a viscoelastic, moisture-retaining layer over the corneal surface, stabilising the tear film and reducing friction with each blink. Cyanocobalamin (vitamin B12) provides antioxidant protection to the corneal epithelium, helping to reduce oxidative stress that can worsen dry eye symptoms. Together, these two ingredients address both the lubrication deficit and the cellular stress associated with dry eye syndrome.

How do I use Artelac Rebalance Eye Drops step by step?

Start by washing your hands thoroughly, then remove any contact lenses before use. Tilt your head back, gently pull down your lower eyelid, and instil one to two drops into the affected eye, then blink gently to distribute the solution. Avoid touching the dropper tip to your eye or any surface, and replace the cap immediately after use to prevent contamination.

How many times a day should I use Artelac Rebalance Eye Drops?

The drops can be used as needed — typically three to five times daily for most adults with dry eye symptoms, though you can use them more frequently if your symptoms require it. There is no strict maximum number of daily applications for preservative-free drops, but you should follow the guidance in the patient information leaflet or ask your pharmacist. If you find you need to use them very frequently, it may be worth speaking to your GP about underlying causes of your dry eye.

Can I use Artelac Rebalance Eye Drops with contact lenses?

You must remove soft contact lenses before instilling the drops and wait at least 15 minutes before reinserting them, as the drops may affect lens material or cause discomfort if used with lenses in place. Hard (rigid gas permeable) lenses should also be removed prior to use. Always check the patient information leaflet for the most up-to-date guidance on contact lens compatibility.

Are Artelac Rebalance Eye Drops preservative-free?

Yes, Artelac Rebalance Eye Drops are completely preservative-free, which makes them a good choice for people with sensitive eyes or those who need to use lubricating drops multiple times throughout the day. Preservatives in some eye drops can cause or worsen ocular surface irritation with prolonged use, so a preservative-free formulation is often preferred for long-term dry eye management. This is particularly relevant for people who already have compromised ocular surface health.

What are the side effects of Artelac Rebalance Eye Drops?

Most people tolerate Artelac Rebalance Eye Drops well, but some may experience temporary blurred vision, mild stinging, or a watery eye immediately after instillation — these effects usually pass within a minute or two. Less commonly, you might notice redness, a foreign body sensation, or slight discharge around the eyelid. If you experience persistent pain, significant vision changes, or signs of an allergic reaction such as eyelid swelling, stop use and consult a healthcare professional promptly.

Who is eligible to use Artelac Rebalance Eye Drops?

Artelac Rebalance Eye Drops are intended for adults experiencing dry eye symptoms such as burning, grittiness, stinging, or tired eyes. They are not recommended for children unless specifically advised by a doctor. People with known allergies to any of the ingredients, active eye infections, or those who have recently undergone eye surgery should consult their doctor before use.

What happens if I miss a dose of Artelac Rebalance Eye Drops?

Because Artelac Rebalance Eye Drops are used on an as-needed basis rather than on a strict dosing schedule, missing an application is not a clinical concern in the same way as missing a prescribed medicine. Simply use the drops when your symptoms return or when you feel your eyes need lubrication. Do not double up on drops to compensate for a missed application.

How long can I use Artelac Rebalance Eye Drops for?

Artelac Rebalance Eye Drops can be used long-term for the ongoing management of dry eye syndrome, as the preservative-free formula is well tolerated with extended use. However, each bottle must be discarded 90 days after first opening, regardless of how much solution remains, to reduce the risk of contamination. If your symptoms persist or worsen despite regular use, speak to your GP or an optometrist for further assessment.

What are the alternatives to Artelac Rebalance Eye Drops?

There are several lubricating eye drops available for dry eye relief, including products containing lower concentrations of hyaluronic acid (such as 0.1% or 0.2%), carbomer-based gels, or carmellose sodium drops. Artelac Rebalance stands out due to its higher 0.32% hyaluronic acid concentration and the addition of vitamin B12 for antioxidant support. Your pharmacist can help you choose the most appropriate product based on your symptom severity and lifestyle.

Can I use Artelac Rebalance Eye Drops if I have allergies or hay fever?

Dry, irritated eyes are a common symptom of allergic conjunctivitis associated with hay fever, and lubricating drops like Artelac Rebalance can help soothe the ocular surface. However, they do not contain antihistamines or anti-allergy agents, so they will not treat the underlying allergic response. If your eye symptoms are primarily allergy-driven, you may also benefit from products in our allergy and hay fever range alongside lubricating drops.

How should I store Artelac Rebalance Eye Drops after opening?

After opening, store the bottle below 25°C in a dry place away from direct sunlight — do not refrigerate or freeze the drops. Keep the cap tightly closed between uses and write the date of opening on the bottle so you can track the 90-day discard deadline. Always keep the bottle out of reach of children and do not use it after the printed expiry date.

Is there any research supporting the use of vitamin B12 in eye drops?

Published clinical research has explored the role of cyanocobalamin (vitamin B12) in ocular surface health, with some studies suggesting it may support corneal nerve regeneration and reduce oxidative stress on the epithelium in dry eye patients. The combination of hyaluronic acid and vitamin B12 in Artelac Rebalance is based on this emerging evidence base. If you'd like to discuss the evidence further, your pharmacist or optometrist can provide personalised guidance.

Can I use Artelac Rebalance Eye Drops during pregnancy or breastfeeding?

There is limited specific data on the use of Artelac Rebalance Eye Drops during pregnancy or breastfeeding, and systemic absorption from topical eye drops is generally considered minimal. However, as a precaution, you should consult your GP or midwife before using any new medicine during pregnancy or whilst breastfeeding. Your healthcare professional can weigh up the potential benefits and any theoretical risks for your individual situation.

How Should You Use Artelac Rebalance Eye Drops?

Using Artelac Rebalance Eye Drops correctly ensures you get the most benefit from each application and reduces the risk of contamination or irritation. Always wash your hands before handling the bottle, and make sure you remove contact lenses before instilling the drops.

What Is the Correct Dose of Artelac Rebalance Eye Drops?

The standard dose is one to two drops instilled into the affected eye or eyes as needed. The frequency will depend on the severity of your dry eye symptoms — some people find relief with three applications a day, while others may need to use the drops more frequently.

When Is the Best Time to Use Artelac Rebalance Eye Drops?

There is no single fixed time of day that is universally best — use the drops whenever your eyes feel dry, uncomfortable, or fatigued. Many people find it helpful to apply them first thing in the morning, before and after prolonged screen use, and before bed to maintain overnight comfort. If you are using other eye drops or ointments, allow at least five minutes between applications and always apply ointments last.

How Long Can You Use Artelac Rebalance Eye Drops For?

Artelac Rebalance Eye Drops are suitable for long-term use in the management of chronic dry eye, as the preservative-free formula is well tolerated over extended periods. Each bottle should be discarded 90 days after first opening — it is a good idea to write the opening date on the label. If your symptoms do not improve after several weeks of regular use, or if they worsen at any point, consult your pharmacist or GP for further assessment and advice.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Artelac Rebalance Eye Drops?

Most people who use Artelac Rebalance Eye Drops experience no significant side effects, particularly because the formula is preservative-free. However, as with any ophthalmic product, some mild effects can occur shortly after instillation.

  • Temporary blurred vision immediately after applying the drops
  • Mild stinging or burning sensation in the eye
  • Watery or teary eyes for a short period after use

These effects are generally brief and resolve within a minute or two as the drops spread across the ocular surface. If blurred vision persists for more than a few minutes, avoid driving or operating machinery until your vision clears.

What Are the Less Common Side Effects of Artelac Rebalance Eye Drops?

Less frequently, some users may notice the following effects. These are not dangerous in most cases but should be monitored, especially if they persist or worsen over time.

  • Redness of the eye (conjunctival hyperaemia)
  • Sensation of a foreign body or grittiness in the eye
  • Slight discharge or crusting around the eyelid margin
  • Mild headache
  • Itching around the eye area

What Are the Serious Side Effects of Artelac Rebalance Eye Drops?

Serious side effects are rare but require immediate attention. Stop using the drops and seek urgent medical advice if you experience any of the following:

  • Sudden or significant changes in vision
  • Severe eye pain that does not resolve quickly
  • Signs of an allergic reaction — including swelling of the eyelids, face, or throat, hives, or difficulty breathing
  • Increasing redness, discharge, or photosensitivity that suggests an eye infection

Allergic reactions to the ingredients in Artelac Rebalance are uncommon, but if you have a known sensitivity to hyaluronic acid or cobalt-containing compounds, discuss this with your pharmacist before use.

What Should You Do If You Experience Side Effects?

For mild, transient side effects such as brief stinging or temporary blurred vision, no specific action is usually needed beyond waiting for the sensation to pass. If you experience persistent or worsening symptoms, discontinue use and consult your pharmacist or GP. You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Artelac Rebalance Eye Drops Interact With Other Medicines?

No clinically significant interactions between Artelac Rebalance Eye Drops and systemic medicines have been reported. However, if you are using other topical eye preparations — including prescribed eye drops, antibiotic drops, or eye ointments — you should leave at least five minutes between each application. Eye ointments should always be applied last. Always inform your pharmacist of all medicines you are currently using, including over-the-counter products.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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