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Anusol Plus HC Ointment Haemorrhoids 4 Way Action

Anusol Plus HC Ointment Haemorrhoids 4 Way Action

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  • ✔️ Relieves haemorrhoid itching, soreness, and swelling fast
  • ✔️ Contains hydrocortisone to actively reduce anal inflammation
  • ✔️ 4-way action targets inflammation, swelling, irritation, and infection risk
  • ✔️ Suitable for both internal and external haemorrhoids in adults
  • ✔️ Includes rectal nozzle applicator for precise internal application

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What Is Anusol Plus HC Ointment for Haemorrhoids?

 

Haemorrhoids — commonly called piles — affect a significant number of adults in the UK at some point in their lives. They can cause itching, soreness, swelling, and discomfort that makes everyday activities genuinely uncomfortable. Anusol Plus HC ointment is a well-established, over-the-counter treatment designed to tackle these symptoms from four angles at once, which is why it's often described as a 4-way action formula. You can find it alongside other haemorrhoid and piles treatments at Cured Pharmacy, available without a prescription for just £6.99.

What sets this product apart from standard Anusol ointment is the inclusion of hydrocortisone acetate, a mild topical corticosteroid. This addition makes it particularly useful when inflammation and persistent itching are the main complaints. It's a trusted name in haemorrhoid care, and for good reason.

 

How Does Anusol Plus HC Ointment Work?

 

The ointment works through a combination of active ingredients, each targeting a different aspect of haemorrhoid discomfort. Here's how the four-way action breaks down:

  • Hydrocortisone acetate (0.25%) — a mild corticosteroid that reduces inflammation, redness, and itching by calming the local immune response in the affected tissue.
  • Zinc oxide — acts as an astringent and skin protectant, helping to soothe irritated tissue and reduce moisture around the anal area.
  • Bismuth subgallate and bismuth oxide — provide astringent and mild antiseptic properties, helping to reduce swelling and protect the mucous membrane.
  • Peru balsam — a natural antiseptic and soothing agent that promotes healing of minor skin damage caused by haemorrhoids.

Together, these ingredients address inflammation, swelling, irritation, and infection risk simultaneously — rather than just masking one symptom at a time.

 

Who Should Use Anusol Plus HC Ointment?

 

This ointment is suitable for adults who are experiencing the typical symptoms of haemorrhoids, particularly when inflammation and itching are prominent. It can be used for both internal and external haemorrhoids. That said, it's not appropriate for everyone, so it's worth checking the suitability criteria before purchasing.

This product may be suitable for you if you:

  • Are an adult aged 18 or over experiencing haemorrhoid symptoms
  • Have itching, soreness, or swelling around the anal area
  • Are dealing with internal or external haemorrhoids that have not been treated with a steroid product recently
  • Have not had rectal bleeding that is unexplained or persistent (always see a GP if you notice rectal bleeding for the first time)

 

How Does Anusol Plus HC Ointment Compare to Standard Anusol Ointment?

 

Feature Anusol Plus HC Ointment Standard Anusol Ointment
Contains hydrocortisone Yes (0.25% hydrocortisone acetate) No
Anti-inflammatory action Yes Limited (astringent only)
Maximum duration of use 7 days without medical advice Up to 7 days (review if no improvement)
Suitable for severe itching/inflammation Yes Less so
OTC availability Yes Yes

 

Is Anusol Plus HC Ointment Stored and Handled Correctly?

 

Proper storage keeps the ointment effective for its full shelf life. Store Anusol Plus HC ointment below 25°C, away from direct sunlight and out of reach of children. Do not use the product after the expiry date printed on the tube or carton. If you're browsing other topical treatments, you might also find our range of creams and ointments useful for related skin concerns.

Once opened, use the ointment within the period indicated on the packaging. Avoid contaminating the nozzle or tube opening by keeping it clean and replacing the cap after each use.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Anusol Plus HC Ointment Haemorrhoids 4 Way Action specifications
Treatment category Haemorrhoids / Anorectal disorders
Mechanism of action Anti-inflammatory (hydrocortisone), astringent (zinc oxide, bismuth compounds), antiseptic and soothing (Peru balsam)
Effective for Internal and external haemorrhoids, itching, soreness, swelling
Suitable for Adults aged 18 and over
Active ingredients Hydrocortisone acetate 0.25%, zinc oxide, bismuth subgallate, bismuth oxide, Peru balsam
UK classification Pharmacy (P) medicine
Drug class Topical corticosteroid combination / Anorectal preparation
Preparation Ointment
Route of administration Topical / Rectal

Specifications of Anusol Plus HC Ointment Haemorrhoids 4 Way Action

 

What Is Anusol Plus HC Ointment and What Is It Used For?

 

Anusol Plus HC Ointment is a topical rectal preparation used to relieve the symptoms of haemorrhoids (piles), including itching, soreness, inflammation, and swelling. It contains five active ingredients working together: hydrocortisone acetate, zinc oxide, bismuth subgallate, bismuth oxide, and Peru balsam. The hydrocortisone component makes it particularly effective when inflammation is a key symptom. It is classified as a Pharmacy (P) medicine in the UK, meaning it is available without a prescription but should be purchased from a registered pharmacy.

Haemorrhoids are swollen blood vessels in or around the rectum and anus. They are extremely common — the NHS notes that around half of all people in the UK will experience them at some point. This ointment is intended for short-term symptomatic relief and is not a cure for the underlying condition.

 

What Do You Need to Know Before Using Anusol Plus HC Ointment?

 

Before using this ointment, read the following carefully. There are situations where this product is not appropriate, and using it incorrectly could delay proper diagnosis or cause harm.

Do not use Anusol Plus HC Ointment if you:

  • Are allergic to hydrocortisone, zinc oxide, bismuth compounds, Peru balsam, or any other ingredient in the formulation
  • Have a fungal or viral infection (such as herpes simplex) in the anal area
  • Are under 18 years of age
  • Have unexplained rectal bleeding — always see a GP first
  • Have tuberculosis affecting the skin

Use with caution and speak to your pharmacist or GP if you:

  • Are pregnant or breastfeeding
  • Have diabetes — topical corticosteroids can occasionally affect blood glucose levels
  • Have used other steroid-containing products in the same area recently
  • Have symptoms that have not improved after 7 days of treatment

Known drug interactions:

  • No clinically significant interactions are expected at topical doses
  • Inform your pharmacist of all medicines you are taking, including herbal remedies

 

How Should You Use Anusol Plus HC Ointment?

 

Always use this ointment exactly as directed on the packaging or as advised by your pharmacist. Do not exceed the recommended dose or duration of use.

  1. Wash your hands thoroughly before and after application.
  2. Clean the affected area gently with mild soap and water, then pat dry.
  3. For external haemorrhoids: apply a small amount of ointment directly to the affected area.
  4. For internal haemorrhoids: attach the rectal nozzle to the tube and gently insert into the rectum, squeezing a small amount of ointment inside.
  5. Apply morning and evening, and after each bowel movement.
  6. Do not use for more than 7 days without medical advice.
Indication Age Group Dose Frequency
External haemorrhoids Adults 18+ Small amount applied topically Morning, evening, and after bowel movements
Internal haemorrhoids Adults 18+ Small amount via rectal nozzle Morning, evening, and after bowel movements
Children under 18 Not applicable Not recommended Not recommended

 

What Are the Possible Side Effects of Anusol Plus HC Ointment?

 

Like all medicines, Anusol Plus HC Ointment can cause side effects, although not everyone experiences them. Most side effects are related to the hydrocortisone component and are more likely with prolonged use. If you're managing other digestive or bowel-related concerns alongside haemorrhoids, you may also find our IBS and cramps range helpful.

Common side effects:

  • Mild burning or stinging sensation on application
  • Temporary local irritation

Less common side effects (more likely with prolonged use):

  • Skin thinning (atrophy) in the treated area
  • Skin discolouration
  • Allergic contact dermatitis — redness, rash, or worsening irritation
  • Adrenal suppression (very rare, only with excessive or prolonged use)

Stop using the ointment and contact your GP or pharmacist if you notice any signs of an allergic reaction, including swelling, severe rash, or difficulty breathing.

 

How Should You Store Anusol Plus HC Ointment?

 

Correct storage ensures the ointment remains safe and effective throughout its shelf life. If you're also managing constipation — a common contributing factor to haemorrhoids — our constipation treatments collection may be worth exploring alongside this product.

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the tube or carton
  • Do not dispose of medicines via wastewater or household waste — return unused medicines to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Anusol Plus HC Ointment online in the UK?

You can buy Anusol Plus HC Ointment online from Cured Pharmacy, a UK GPhC-registered online pharmacy, for just £6.99. It is available without a prescription and can be found in our haemorrhoids and piles collection. It is also stocked in some high street pharmacies and supermarkets across the UK.

How does Anusol Plus HC Ointment work in the body?

Anusol Plus HC Ointment works through four complementary mechanisms. Hydrocortisone acetate reduces inflammation and itching by suppressing the local immune response, while zinc oxide and bismuth compounds act as astringents to shrink swollen tissue. Peru balsam provides antiseptic and soothing properties to support healing of irritated skin around the anal area.

How do I apply Anusol Plus HC Ointment step by step?

Start by washing your hands and cleaning the affected area gently. For external haemorrhoids, apply a small amount of ointment directly to the skin. For internal haemorrhoids, attach the rectal nozzle to the tube and insert it gently before squeezing a small amount inside. Apply morning and evening, and after each bowel movement, for up to 7 days.

How long does it take for Anusol Plus HC Ointment to work?

Many people notice some relief from itching and soreness within the first day or two of use, as the hydrocortisone begins to reduce inflammation. Full symptomatic improvement typically occurs within 5 to 7 days of consistent use. If your symptoms have not improved after 7 days, stop using the product and consult your GP or pharmacist.

What is the correct dose of Anusol Plus HC Ointment?

Apply a small amount of ointment to the affected area in the morning, in the evening, and after each bowel movement. Do not apply more than directed, as excessive use of hydrocortisone-containing products can cause skin thinning. The maximum recommended duration of use without medical advice is 7 days.

What are the side effects of Anusol Plus HC Ointment and how do I manage them?

The most common side effects include mild burning or stinging on application and temporary local irritation, which usually settle quickly. With prolonged use, skin thinning or discolouration may occur — this is why the 7-day limit is important. If you experience worsening symptoms, an allergic reaction, or unusual skin changes, stop using the ointment and speak to your pharmacist or GP promptly.

Is Anusol Plus HC Ointment safe to use during pregnancy?

Haemorrhoids are very common during pregnancy, but you should speak to your doctor or midwife before using Anusol Plus HC Ointment, as it contains hydrocortisone. While topical corticosteroids are generally considered low risk when used sparingly and for short periods, medical guidance is always recommended during pregnancy. Your GP or midwife can advise on the safest option for you.

Who is eligible to use Anusol Plus HC Ointment?

Anusol Plus HC Ointment is suitable for adults aged 18 and over who are experiencing haemorrhoid symptoms such as itching, soreness, or swelling. It is not recommended for children under 18, or for anyone with a fungal or viral infection in the anal area, unexplained rectal bleeding, or a known allergy to any of the ingredients. Always check with a pharmacist if you are unsure.

What is the difference between Anusol Plus HC Ointment and standard Anusol Ointment?

The key difference is that Anusol Plus HC Ointment contains hydrocortisone acetate (0.25%), a mild corticosteroid that actively reduces inflammation and itching. Standard Anusol Ointment does not contain a corticosteroid and relies solely on astringent and antiseptic ingredients. If inflammation and persistent itching are your main symptoms, the HC version is generally more appropriate.

Can I use Anusol Plus HC Ointment for internal haemorrhoids?

Yes, Anusol Plus HC Ointment is suitable for both internal and external haemorrhoids. For internal use, attach the rectal nozzle applicator provided with the product to the tube and insert it gently into the rectum before applying. Always follow the instructions in the patient information leaflet carefully to ensure safe and effective use.

How long can you use Anusol Plus HC Ointment for?

You should not use Anusol Plus HC Ointment for more than 7 days without seeking medical advice. Prolonged use of hydrocortisone-containing products can lead to skin thinning in the treated area. If your symptoms persist beyond 7 days, see your GP to rule out other causes and discuss further treatment options.

What happens if I miss a dose of Anusol Plus HC Ointment?

If you forget to apply the ointment at your usual time, simply apply it as soon as you remember. Do not apply a double dose to make up for a missed application. Continue with your regular schedule — morning, evening, and after bowel movements — for the remainder of the 7-day course.

Are there any alternatives to Anusol Plus HC Ointment?

Yes, there are several alternatives available for haemorrhoid relief, including Proctosedyl Ointment (which also contains hydrocortisone and cinchocaine), Scheriproct Ointment, and standard Anusol Ointment or suppositories for milder symptoms. You can browse the full range in our haemorrhoids and piles collection to compare options. Your pharmacist can help you choose the most appropriate product for your symptoms.

Can constipation make haemorrhoids worse, and should I treat both?

Yes, straining during bowel movements due to constipation is one of the most common causes and aggravating factors for haemorrhoids. Treating constipation alongside haemorrhoid symptoms can significantly speed up recovery and prevent recurrence. You can explore our constipation treatments range for suitable options, and speak to your pharmacist about a combined approach.

What does the latest research say about hydrocortisone for haemorrhoids?

Clinical evidence supports the short-term use of topical hydrocortisone for reducing inflammation and itching associated with haemorrhoids, and it is included in NHS-recommended treatment options for symptomatic relief. The BNF confirms that anorectal preparations containing corticosteroids are appropriate for short-term use in adults. Long-term use is not recommended due to the risk of skin atrophy, and lifestyle measures such as increased fibre intake and hydration remain the cornerstone of haemorrhoid management according to NHS guidance.

How Should You Use Anusol Plus HC Ointment?

Using Anusol Plus HC Ointment correctly makes a real difference to how quickly your symptoms improve. Always wash your hands before and after application, and clean the affected area gently with mild soap and water before applying the ointment.

What Is the Correct Dose of Anusol Plus HC Ointment?

The recommended dose is a small amount applied to the affected area up to three times daily. Do not apply more than directed, as overuse of hydrocortisone-containing products can cause unwanted effects such as skin thinning.

When Is the Best Time to Use Anusol Plus HC Ointment?

Apply the ointment in the morning, in the evening, and after each bowel movement for the most consistent relief. Applying after a bowel movement is particularly important, as this is when the anal area is most irritated and when the ointment can provide the most immediate soothing effect. Keeping to a regular routine helps maintain a steady level of symptom control throughout the day.

How Long Can You Use Anusol Plus HC Ointment For?

You should use Anusol Plus HC Ointment for a maximum of 7 days without seeking medical advice. Because it contains hydrocortisone, prolonged use beyond this period can lead to skin thinning (atrophy) in the treated area. If your symptoms have not improved after 7 days, or if they worsen at any point, stop using the ointment and consult your GP or pharmacist for further assessment. Addressing contributing factors such as constipation and low dietary fibre intake is also important for long-term management of haemorrhoids.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Anusol Plus HC Ointment?

Most people tolerate Anusol Plus HC Ointment well, particularly when used as directed for short periods. However, as with any medicine, some people may experience side effects. The most common ones are mild and tend to settle quickly once your body adjusts to the product.

  • Mild burning or stinging sensation immediately after application
  • Temporary local irritation around the anal area
  • Mild itching at the site of application

What Are the Less Common Side Effects of Anusol Plus HC Ointment?

Less common side effects are more likely to occur if the ointment is used for longer than the recommended 7 days, or if it is applied in excessive amounts. These effects are primarily related to the hydrocortisone component of the formulation.

  • Skin thinning (atrophy) in the treated area
  • Skin discolouration or changes in pigmentation
  • Stretch marks (striae) with prolonged use
  • Allergic contact dermatitis — presenting as increased redness, rash, or worsening irritation

What Are the Serious Side Effects of Anusol Plus HC Ointment?

Serious side effects from Anusol Plus HC Ointment are rare, especially when the product is used correctly and for no longer than 7 days. However, you should be aware of the following and seek medical attention promptly if they occur.

  • Signs of a severe allergic reaction (anaphylaxis): swelling of the face, lips, or throat, difficulty breathing, or a widespread rash — call 999 immediately
  • Adrenal suppression: extremely rare with topical use, but possible with excessive or prolonged application — symptoms may include unusual fatigue, dizziness, or weight loss
  • Worsening of an existing infection in the treated area

What Should You Do If You Experience Side Effects of Anusol Plus HC Ointment?

If you experience mild side effects such as temporary stinging or irritation, these usually resolve on their own and do not require you to stop treatment. However, if side effects are persistent, worsening, or causing significant discomfort, stop using the ointment and speak to your pharmacist or GP. You should also stop use immediately and seek urgent medical attention if you notice any signs of a serious allergic reaction. Never continue using a product that is clearly making your symptoms worse.

Can Anusol Plus HC Ointment Interact With Other Medicines?

No clinically significant drug interactions are expected with Anusol Plus HC Ointment when used topically at the recommended dose. However, if you are using other corticosteroid-containing products — whether topical, inhaled, or oral — the combined effect on adrenal function should be considered, particularly with prolonged use. Always inform your pharmacist of all medicines you are currently taking, including over-the-counter products and herbal remedies, so they can advise you appropriately.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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