Skip to product information
1 of 1

  • Images are for illustration purposes only

Anusol Plus HC - 12 Suppositories

Anusol Plus HC - 12 Suppositories

  • 1. Ozempic®️-equivalent therapy now available for weight management
  • 2. Average weight loss of 17%, with 1 in 3 patients achieving over 20%
  • 3. May help reduce osteoarthritis-related pain
  • 4. Wegovy®️ is not expected to impact the effectiveness of oral contraceptives
  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Relieves internal haemorrhoid itching, pain and inflammation
  • ✔️ Contains hydrocortisone acetate for targeted anti-inflammatory action
  • ✔️ Soothes and protects rectal tissue with zinc oxide and bismuth
  • ✔️ Suitable for adults 18+ experiencing internal piles symptoms
  • ✔️ Convenient 12-suppository pack for a complete short-course treatment

Price Checker

Regular price £7.09
Sale price £7.09
Sale Sold out
  • Lowest price guarantee
  • Includes FREE private prescription
View full details

 

What Are Anusol Plus HC Haemorrhoid Suppositories?

 

Piles can be genuinely uncomfortable — and for many people, embarrassing to talk about. The good news is that effective treatment is available without a prescription. Haemorrhoid suppositories like Anusol Plus HC are specifically designed to target internal haemorrhoids directly at the source, delivering active ingredients where they are needed most. Each pack contains 12 suppositories, making it a practical short-course treatment for adults dealing with the pain, itching, and swelling that piles can cause. You can browse the full range of treatments in our haemorrhoids and piles collection if you want to compare options.

Haemorrhoids — commonly called piles — are swollen blood vessels inside or around the back passage. They affect a significant proportion of UK adults at some point in their lives, and internal haemorrhoids in particular can cause bleeding, discomfort, and a feeling of incomplete bowel emptying. Anusol Plus HC suppositories are formulated to address these symptoms with a combination of ingredients that reduce inflammation, soothe irritated tissue, and protect the rectal mucosa.

 

How Does Anusol Plus HC Work Inside the Body?

 

The suppository format allows the active ingredients to be released directly into the lower rectum, where internal haemorrhoids develop. Once inserted, the suppository dissolves at body temperature and the ingredients get to work quickly. Here is how each component contributes:

  • Hydrocortisone acetate (0.25%) — a mild corticosteroid that reduces inflammation, swelling, and itching associated with haemorrhoids
  • Zinc oxide — acts as an astringent and skin protectant, helping to reduce irritation and minor bleeding
  • Bismuth subgallate and bismuth oxide — astringent and antiseptic properties that help protect inflamed tissue
  • Balsam Peru — promotes healing of damaged skin and has mild antiseptic action

Together, these ingredients work in a complementary way. The hydrocortisone tackles the inflammatory response, while the astringent and protective agents help the tissue recover. It is a well-established combination that has been used in haemorrhoid treatment for many years.

 

Who Is Anusol Plus HC Suitable For?

 

Anusol Plus HC suppositories are intended for adults aged 18 and over who are experiencing symptoms of internal haemorrhoids. They are particularly useful when symptoms include significant inflammation or itching that has not responded adequately to non-corticosteroid treatments. That said, they are not appropriate for everyone.

This product may be suitable for you if:

  • You are an adult (18 years or over) with diagnosed or suspected internal haemorrhoids
  • You are experiencing itching, discomfort, or mild bleeding from internal piles
  • You have not found relief from standard haemorrhoid creams or ointments alone
  • You are not pregnant, breastfeeding, or immunocompromised (without first seeking medical advice)

If you are unsure whether this product is right for you, speak to a pharmacist before purchasing. Rectal bleeding should always be assessed by a GP to rule out other causes.

 

How Does Anusol Plus HC Compare to Standard Anusol Suppositories?

 

Feature Anusol Plus HC Suppositories Standard Anusol Suppositories
Contains hydrocortisone Yes (0.25% hydrocortisone acetate) No
Reduces inflammation Yes — corticosteroid action Mild — astringent action only
Maximum duration of use 7 days without medical advice 7 days without medical advice
Suitable for children No (18+ only) No (12+ with caution)

 

How Should You Store Anusol Plus HC Suppositories?

 

Proper storage matters more than you might think with suppositories. Store Anusol Plus HC below 25°C in a cool, dry place — away from direct sunlight and heat sources. Do not refrigerate unless the packaging specifically instructs you to, as this can make insertion uncomfortable. Keep the product out of reach and sight of children at all times.

Check the expiry date on the pack before use. If the suppositories appear discoloured, misshapen, or have an unusual odour, do not use them. Using these haemorrhoid suppositories correctly — including proper storage — helps ensure you get the full benefit of the treatment. If you are also managing related digestive discomfort, you may find our constipation collection helpful, as straining during bowel movements is a common trigger for piles.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Anusol Plus HC 12 Suppositories specifications
Treatment category Haemorrhoids and piles
Mechanism of action Anti-inflammatory (corticosteroid), astringent, and tissue-protective
Effective for Internal haemorrhoids — itching, inflammation, discomfort, minor bleeding
Suitable for Adults aged 18 and over
Active ingredients Hydrocortisone acetate 0.25%, zinc oxide, bismuth subgallate, bismuth oxide, balsam Peru
Pack size 12 suppositories
UK classification Pharmacy (P) medicine
Drug class Topical corticosteroid combination
Preparation Rectal suppository
Route of administration Rectal

Specifications of Anusol Plus HC 12 Suppositories

 

What Is Anusol Plus HC and What Is It Used For?

 

Anusol Plus HC suppositories are a pharmacy (P) medicine used to treat the symptoms of internal haemorrhoids in adults. Haemorrhoids are swollen veins in the lower rectum or around the anus. Internal haemorrhoids sit inside the rectum and can cause itching, discomfort, a feeling of fullness, and sometimes minor bleeding after a bowel movement. Anusol Plus HC combines a mild corticosteroid with astringent and protective agents to relieve these symptoms. It is not a cure for haemorrhoids, but it can significantly reduce discomfort during a flare-up. If you experience persistent or heavy rectal bleeding, you must see a GP — do not self-treat without a diagnosis.

 

What Do You Need to Know Before Using Anusol Plus HC?

 

Before using these suppositories, read the following carefully. There are situations where this product is not appropriate, and using it incorrectly could cause harm.

Do not use Anusol Plus HC if you:

  • Are allergic to any of the active or inactive ingredients
  • Have a fungal, viral, or bacterial infection around the anal area
  • Are under 18 years of age
  • Are pregnant or breastfeeding without first consulting your doctor
  • Have tuberculosis affecting the skin or perianal area

Use with caution if you:

  • Have diabetes — corticosteroids can affect blood glucose levels
  • Are immunocompromised or taking immunosuppressant medicines
  • Have used corticosteroid-containing products for a prolonged period previously

Drug interactions to be aware of:

  • No significant systemic drug interactions are expected at the recommended rectal dose
  • Inform your pharmacist if you are using other corticosteroid-containing products simultaneously
  • If you are taking medicines that affect the immune system, seek advice before use

 

How Should You Use Anusol Plus HC Suppositories?

 

Using suppositories correctly makes a real difference to how well they work. Follow these steps carefully each time:

  1. Wash your hands thoroughly with soap and water before handling the suppository
  2. If possible, empty your bowels before inserting the suppository
  3. Remove the foil wrapper completely from the suppository
  4. Lie on your side with your knees drawn up towards your chest
  5. Gently insert the suppository, pointed end first, into the back passage as far as is comfortable
  6. Remain lying down for a few minutes to allow the suppository to dissolve
  7. Wash your hands again thoroughly after use
Indication Age Group Dose Frequency
Internal haemorrhoids Adults 18+ 1 suppository Morning, night, and after each bowel movement — maximum 4 per day
Internal haemorrhoids Under 18 Not suitable Not applicable

Do not use more than 4 suppositories in 24 hours. Do not use for longer than 7 days without seeking medical advice. If symptoms have not improved after 7 days, consult your GP. You might also find it helpful to explore our pain relief collection for complementary options to manage discomfort during recovery.

 

What Are the Possible Side Effects of Anusol Plus HC?

 

Like all medicines, Anusol Plus HC can cause side effects, although not everyone experiences them. Because the hydrocortisone is applied locally and at a low concentration, systemic side effects are unlikely at the recommended dose and duration.

Common side effects:

  • Mild local burning or stinging sensation after insertion
  • Temporary increase in itching immediately after use
  • Minor local irritation around the anal area

Less common side effects:

  • Skin thinning (atrophy) around the anal area — more likely with prolonged use beyond 7 days
  • Hypersensitivity or allergic reaction (rash, increased redness, swelling) — stop use immediately if this occurs
  • Worsening of any existing infection in the area

Stop using the product and contact your pharmacist or GP if you notice any signs of an allergic reaction, if symptoms worsen, or if you develop new symptoms during treatment.

 

How Should You Store Anusol Plus HC Suppositories?

 

Correct storage keeps the suppositories effective and safe to use. Follow these guidelines:

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Do not freeze or refrigerate unless specifically instructed
  • Keep the product in its original packaging until use
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the pack
  • Do not dispose of medicines via wastewater or household waste — return unused medicines to your pharmacy

If you are managing other digestive health concerns alongside haemorrhoids, our IBS and cramps collection includes a range of products that may help with associated bowel discomfort.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Anusol Plus HC suppositories online in the UK?

You can buy Anusol Plus HC 12 suppositories directly from Cured Pharmacy, a UK GPhC-registered online pharmacy. They are available as an over-the-counter pharmacy medicine for adults aged 18 and over. No prescription is required, but a pharmacist check is completed before dispatch to ensure suitability.

How do Anusol Plus HC suppositories work in the body?

Once inserted rectally, the suppository dissolves at body temperature and releases its active ingredients directly into the lower rectum. Hydrocortisone acetate reduces inflammation and itching, while zinc oxide and bismuth compounds act as astringents to soothe and protect the swollen tissue. Balsam Peru supports tissue healing and provides mild antiseptic action.

How do I insert Anusol Plus HC suppositories correctly?

Wash your hands before and after use. Remove the foil wrapper, lie on your side with knees drawn up, and gently insert the suppository pointed end first into the back passage. Stay lying down for a few minutes to allow it to dissolve fully before getting up.

What is the correct dose of Anusol Plus HC suppositories?

The recommended dose for adults is one suppository inserted into the back passage in the morning, at night, and after each bowel movement. Do not use more than four suppositories in any 24-hour period. Always follow the instructions in the patient information leaflet.

How long can I use Anusol Plus HC suppositories for?

Anusol Plus HC should not be used for more than 7 consecutive days without seeking medical advice. Prolonged use of hydrocortisone-containing products can lead to skin thinning around the anal area. If your symptoms have not improved within a week, consult your GP.

What are the side effects of Anusol Plus HC suppositories?

Most people tolerate Anusol Plus HC well. Possible side effects include mild local burning, stinging, or temporary itching after insertion. Less commonly, prolonged use may cause skin thinning or a hypersensitivity reaction — if you notice increased redness, swelling, or a rash, stop use and speak to a pharmacist or GP.

Can I use Anusol Plus HC suppositories during pregnancy?

You should consult your doctor or pharmacist before using Anusol Plus HC if you are pregnant or breastfeeding. Hydrocortisone-containing products are generally used with caution during pregnancy, and a healthcare professional can advise on the safest option for your situation. Do not self-treat without seeking advice first.

Are Anusol Plus HC suppositories suitable for children?

No — Anusol Plus HC suppositories are not suitable for anyone under 18 years of age. If a child is experiencing anal discomfort or symptoms that suggest haemorrhoids, a GP should be consulted for appropriate assessment and treatment. Do not use this product in children.

What is the difference between Anusol and Anusol Plus HC?

The key difference is the inclusion of hydrocortisone acetate in Anusol Plus HC, which is a mild corticosteroid that actively reduces inflammation. Standard Anusol products do not contain a corticosteroid and rely solely on astringent and protective ingredients. Anusol Plus HC is therefore more appropriate when inflammation and itching are the predominant symptoms.

What happens if I miss a dose of Anusol Plus HC?

If you forget to use a suppository at the scheduled time, simply use it as soon as you remember — unless it is nearly time for your next dose. In that case, skip the missed dose and continue as normal. Do not use two suppositories at once to make up for a missed one.

Can I use Anusol Plus HC suppositories alongside other haemorrhoid treatments?

Using multiple corticosteroid-containing products simultaneously is not recommended, as this increases the risk of side effects such as skin thinning. If you are already using a haemorrhoid cream or ointment, check with your pharmacist before adding suppositories. You can explore our haemorrhoids and piles collection to compare available options.

Who is eligible to buy Anusol Plus HC suppositories without a prescription?

Adults aged 18 and over who are experiencing symptoms of internal haemorrhoids can purchase Anusol Plus HC as an over-the-counter pharmacy medicine. It is not suitable for people with infections around the anal area, those who are pregnant or breastfeeding without medical advice, or those with certain skin conditions in the affected area.

What are the alternatives to Anusol Plus HC suppositories?

Alternatives include standard Anusol suppositories (without hydrocortisone), Scheriproct suppositories, or topical haemorrhoid creams and ointments. The right choice depends on the severity of your symptoms and whether inflammation is a significant factor. A pharmacist can help you choose the most appropriate product from our creams and ointments collection.

Can constipation make haemorrhoids worse, and should I treat it too?

Yes — straining during bowel movements due to constipation is one of the most common triggers for haemorrhoids and can worsen existing ones. Alongside using Anusol Plus HC, it is worth addressing constipation through dietary changes, increased fluid intake, and if needed, a suitable laxative. Speak to your pharmacist for personalised advice.

What are the latest guidelines on treating haemorrhoids in the UK?

Current NHS guidance recommends lifestyle measures — including a high-fibre diet, adequate hydration, and avoiding straining — as the first-line approach for managing haemorrhoids. Over-the-counter treatments such as haemorrhoid suppositories containing hydrocortisone are recommended for short-term symptom relief. Persistent or severe haemorrhoids may require referral for procedures such as banding or surgery.

How Should You Use Anusol Plus HC Suppositories?

Using Anusol Plus HC correctly ensures the active ingredients reach the right place and work as effectively as possible. Always wash your hands thoroughly before and after handling the suppository, and try to use it at the same times each day to maintain consistent symptom relief.

Follow these steps each time you use a suppository:

What Is the Correct Dose of Anusol Plus HC Suppositories?

The dose depends on the frequency of your bowel movements and the severity of your symptoms. Do not exceed the maximum daily dose of four suppositories in any 24-hour period, regardless of symptom severity.

When Is the Best Time to Use Anusol Plus HC Suppositories?

The most effective times to use Anusol Plus HC are in the morning after waking, at night before bed, and after each bowel movement. Using the suppository after a bowel movement means the rectum is empty, which allows the ingredients to be absorbed more effectively and reduces the chance of the suppository being expelled too quickly.

Try to build use into your daily routine — for example, keeping the pack in the bathroom as a reminder. Consistency matters more than perfect timing, so if you miss a scheduled dose, simply use it as soon as you remember rather than doubling up.

How Long Can You Use Anusol Plus HC Suppositories For?

Anusol Plus HC should be used for the shortest time necessary to relieve your symptoms. Because it contains hydrocortisone, a mild corticosteroid, it should not be used for more than 7 consecutive days without seeking medical advice. Prolonged use beyond this period increases the risk of skin thinning around the anal area.

If your symptoms have not improved after 7 days, or if they worsen at any point during treatment, stop using the product and consult your GP. Rectal bleeding that is new, heavy, or unexplained should always be assessed by a doctor — do not continue self-treating without a diagnosis.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

Customer Reviews

Based on 1 review
100%
(1)
0%
(0)
0%
(0)
0%
(0)
0%
(0)
H
Humairah
Good item

Very good item. Worked well.

What Are the Most Common Side Effects of Anusol Plus HC?

Most people who use Anusol Plus HC suppositories at the recommended dose and duration do not experience significant side effects. However, as with any medicine applied to sensitive tissue, some local reactions can occur. These are usually mild and resolve on their own once treatment is stopped.

  • Mild burning or stinging sensation immediately after insertion
  • Temporary increase in itching around the anal area shortly after use
  • Minor local irritation or discomfort

What Are the Less Common Side Effects of Anusol Plus HC?

Less common side effects are more likely to occur if the product is used for longer than the recommended 7-day period or at higher than the recommended dose. If you notice any of the following, stop using the product and speak to a pharmacist or GP.

  • Skin thinning (atrophy) around the anal area — a known risk with prolonged corticosteroid use
  • Hypersensitivity or allergic reaction, including increased redness, swelling, or a rash
  • Worsening of any pre-existing infection in the perianal area
  • Discolouration or changes to the skin around the back passage

What Are the Serious Side Effects of Anusol Plus HC?

Serious systemic side effects from Anusol Plus HC are very unlikely when the product is used correctly at the recommended dose and for no more than 7 days. The amount of hydrocortisone absorbed into the bloodstream through rectal use is minimal. However, if you use multiple corticosteroid-containing products simultaneously, or use this product for an extended period, there is a theoretical risk of systemic corticosteroid effects such as adrenal suppression.

Seek urgent medical attention if you experience signs of a severe allergic reaction, including difficulty breathing, swelling of the face or throat, or a widespread skin rash. These reactions are rare but require immediate assessment.

What Should You Do If You Experience Side Effects?

If you experience mild local irritation that is tolerable, you may continue using the product but monitor your symptoms closely. If irritation worsens, or if you develop new symptoms such as a rash, increased swelling, or signs of infection, stop using Anusol Plus HC immediately. Contact your pharmacist in the first instance — they can advise whether you need to see a GP.

You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. This helps improve medicine safety information for everyone.

Can Anusol Plus HC Interact With Other Medicines?

At the recommended rectal dose, Anusol Plus HC is not expected to cause significant interactions with other medicines. However, using it alongside other corticosteroid-containing products — whether topical, inhaled, or oral — may increase the overall corticosteroid load on your body. Always tell your pharmacist about all medicines you are currently taking, including over-the-counter products and supplements, before starting Anusol Plus HC.

If you are taking immunosuppressant medicines or have a condition that affects your immune system, seek medical advice before use, as corticosteroids can further suppress immune function even when applied locally.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

We’re a safe and
regulated UK service

Registered Pharmacy Badge

Lowest Price Guarantee

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

100% discreet packaging

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

Agent

Need help?
Talk to our friendly experts now

How our service works

Service Setup

Service setup

Discreet Packaging

Discreet packaging

Express Delivery

Express delivery