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Anusol 12 Suppositories 3 Way Action

Anusol 12 Suppositories 3 Way Action

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  • ✔️ Targets internal haemorrhoids with 3-way astringent action
  • ✔️ Soothes rectal irritation and reduces haemorrhoidal swelling
  • ✔️ Zinc oxide and bismuth provide antiseptic and astringent relief
  • ✔️ Suitable for adults and children aged 12 and over
  • ✔️ Discreet rectal suppository format for internal pile treatment

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Are Anusol Suppositories for Piles Right for You?

 

Haemorrhoids — commonly called piles — are swollen blood vessels inside or around the rectum and anus. They affect a significant number of adults in the UK at some point in their lives, causing discomfort, itching, and sometimes bleeding. If you're dealing with internal piles, Anusol suppositories for piles offer a targeted, pharmacist-recommended option that works directly at the source of the problem. Available over the counter for just £5.79, this pack of 12 suppositories is a practical, discreet solution you can use at home. You can browse the full range of treatments in our haemorrhoids and piles collection.

Anusol has been a trusted name in haemorrhoid care for decades. The 3-way action formula combines astringent, antiseptic, and soothing properties to address the multiple symptoms that internal piles can cause. It's not a prescription medicine — you can order it directly without needing to see a GP first.

 

How Does Anusol 3 Way Action Work on Internal Haemorrhoids?

 

The suppository format means the active ingredients are delivered precisely where internal haemorrhoids develop — inside the lower rectum. Once inserted, the suppository dissolves at body temperature, releasing its active ingredients across the affected tissue. Here's how each component contributes:

  • Zinc oxide — acts as an astringent, helping to shrink swollen tissue and reduce the engorgement associated with haemorrhoids
  • Bismuth subgallate and bismuth oxide — provide mild antiseptic action, helping to protect irritated mucous membranes from infection
  • Balsam Peru — soothes inflamed tissue and promotes a more comfortable healing environment

Together, these ingredients address swelling, irritation, and the risk of secondary infection — three of the most common complaints associated with internal piles.

 

Who Is Anusol 12 Suppositories Suitable For?

 

These suppositories are designed specifically for internal haemorrhoids. They're suitable for adults and children aged 12 and over. That said, there are some groups who should take extra care or seek advice before using them.

Anusol suppositories are generally suitable for:

  • Adults experiencing internal haemorrhoid symptoms such as itching, discomfort, or mild bleeding
  • People who have already tried dietary and lifestyle changes (such as increasing fibre and fluid intake) but still need symptomatic relief
  • Those who prefer a rectal suppository over a topical cream for internal symptoms
  • Adults aged 12 and over who do not have a known allergy to any of the listed ingredients

If you are pregnant, breastfeeding, or have a history of rectal bleeding that has not been investigated by a doctor, please speak to a healthcare professional before using this product.

 

How Does Anusol Suppositories Compare to Anusol Cream?

 

Feature Anusol 12 Suppositories Anusol Cream
Best for Internal haemorrhoids External haemorrhoids
Route of use Rectal (inserted) Topical (applied externally)
Active ingredients Zinc oxide, bismuth compounds, Balsam Peru Zinc oxide, bismuth compounds, Balsam Peru
Pack size 12 suppositories Varies (typically 23g or 43g)

 

How Should You Store Anusol Suppositories?

 

Store Anusol suppositories below 25°C in a cool, dry place, away from direct sunlight. Do not store them in the bathroom, as heat and humidity can cause suppositories to soften before use. Keep them out of the reach and sight of children. If you're also managing digestive discomfort alongside your piles symptoms, it may be worth exploring our constipation collection, as straining during bowel movements is a common trigger for haemorrhoids.

Do not use after the expiry date printed on the packaging. If a suppository has softened, you can firm it up briefly by placing it (still in its wrapper) in cold water before use.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Anusol 12 Suppositories 3 Way Action specifications
Treatment category Haemorrhoids / Piles
Mechanism of action Astringent, antiseptic, and soothing action on rectal mucosa
Effective for Internal haemorrhoids (itching, discomfort, swelling)
Suitable for Adults and children aged 12 and over
Active ingredients Zinc oxide, Bismuth subgallate, Bismuth oxide, Balsam Peru
Pack size 12 suppositories
UK classification General Sale Medicine (GSL)
Drug class Haemorrhoidal preparation
Preparation Rectal suppository
Route of administration Rectal

Specifications of Anusol 12 Suppositories 3 Way Action

 

What Is Anusol 12 Suppositories and What Is It Used For?

 

Anusol 12 Suppositories 3 Way Action is an over-the-counter rectal medicine used to relieve the symptoms of internal haemorrhoids. Haemorrhoids are swollen veins in the lower rectum or anus. When they develop internally, they can cause itching, a feeling of fullness or discomfort, and occasionally bright red bleeding after a bowel movement. The NHS notes that piles are very common and often improve on their own, but symptomatic treatments can help manage discomfort in the meantime.

Each suppository contains a combination of zinc oxide, bismuth subgallate, bismuth oxide, and Balsam Peru. These ingredients work together to reduce swelling, protect the mucous membrane, and soothe irritated tissue. Anusol suppositories for piles are not a cure — they relieve symptoms while the body heals. They are not intended for external haemorrhoids; for those, a cream or ointment formulation would be more appropriate.

 

What Do You Need to Know Before Using Anusol Suppositories?

 

Before using these suppositories, read the following carefully. Some people should not use this product or should seek medical advice first.

Do not use Anusol suppositories if you:

  • Are allergic to zinc oxide, bismuth compounds, Balsam Peru, or any other listed ingredient
  • Are under 12 years of age
  • Have rectal bleeding that has not been assessed by a doctor
  • Have a known sensitivity to any component of the suppository base

Speak to your doctor or pharmacist before use if you:

  • Are pregnant or breastfeeding
  • Have inflammatory bowel disease or any other diagnosed rectal condition
  • Have symptoms that have not improved after 7 days of treatment
  • Notice a significant increase in rectal bleeding

Drug interactions:

  • No significant drug interactions are currently known for topically applied haemorrhoidal preparations containing these ingredients
  • Always inform your pharmacist of all medicines you are taking, including herbal remedies

 

How Should You Use Anusol 12 Suppositories Correctly?

 

Using suppositories correctly makes a real difference to how well they work. Follow these steps carefully each time.

  1. Wash your hands thoroughly before and after use
  2. Remove the foil wrapper from the suppository
  3. Lie on your side with your knees drawn up towards your chest
  4. Gently insert the suppository, pointed end first, into the rectum
  5. Remain lying down for a few minutes to allow the suppository to dissolve
  6. Wash your hands again after use
Indication Age Group Dose Frequency
Internal haemorrhoids Adults and children 12+ 1 suppository Morning, night, and after each bowel movement (max 4 per day)
Internal haemorrhoids Under 12 years Not recommended Consult a GP

Do not use for more than 7 days without consulting a doctor. If you're also experiencing digestive symptoms such as bloating or cramping alongside your piles, our IBS and cramps collection may have relevant products to support your overall gut health.

 

What Are the Possible Side Effects of Anusol Suppositories?

 

Like all medicines, Anusol suppositories can cause side effects, although not everyone experiences them. Most people tolerate this product well when used as directed.

Common side effects:

  • Mild local irritation or a burning sensation at the site of insertion
  • Temporary discomfort immediately after use

Less common side effects:

  • Allergic skin reaction (redness, rash, or swelling around the anal area)
  • Increased local irritation if used more frequently than recommended

Stop using the product and seek medical advice if you develop signs of an allergic reaction, including significant swelling, severe itching, or difficulty breathing. Rectal bleeding that worsens during treatment should always be assessed by a GP promptly.

 

How Should You Store Anusol 12 Suppositories?

 

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and sources of heat
  • Do not store in the bathroom or near a sink
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the outer carton
  • If a suppository has softened, place it (in its wrapper) in cold water for a few minutes before use
  • Do not freeze

If you need to dispose of unused suppositories, do not flush them down the toilet or put them in household waste. Return them to your local pharmacy for safe disposal. You can also find additional support products in our pain relief collection if you need help managing associated discomfort.

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Frequently Asked Questions

Where can I buy Anusol suppositories for piles online in the UK?

You can buy Anusol 12 Suppositories 3 Way Action online from Cured Pharmacy for just £5.79, with no prescription required. They are available as a general sale medicine, meaning you can order them quickly and discreetly. Browse the full range in our haemorrhoids and piles collection for additional treatment options.

How do Anusol suppositories work for internal haemorrhoids?

Anusol suppositories work through a 3-way action: zinc oxide acts as an astringent to reduce swelling, bismuth compounds provide antiseptic protection against infection, and Balsam Peru soothes inflamed rectal tissue. The suppository dissolves at body temperature, releasing the active ingredients directly onto the affected area. This targeted delivery makes them particularly effective for internal haemorrhoids that cannot be reached by a topical cream.

How do I insert an Anusol suppository correctly?

Wash your hands, remove the foil wrapper, and lie on your side with your knees drawn up. Gently insert the suppository pointed end first into the rectum, then remain lying down for a few minutes to allow it to dissolve fully. Wash your hands again afterwards and avoid a bowel movement for at least an hour if possible.

What is the correct dose of Anusol suppositories?

The recommended dose for adults and children aged 12 and over is one suppository in the morning, one at night, and one after each bowel movement — up to a maximum of four suppositories per day. Do not exceed this dose. If your symptoms have not improved after 7 days, stop use and consult your GP or pharmacist.

How long does it take for Anusol suppositories to work?

Many people notice some improvement in symptoms such as itching and discomfort within a few days of starting treatment. However, the time to relief can vary depending on the severity of your haemorrhoids and whether you are also making lifestyle changes such as increasing dietary fibre. If there is no improvement after 7 days, seek medical advice.

Can I use Anusol suppositories during pregnancy?

Haemorrhoids are common during pregnancy, but you should always consult your midwife or GP before using any medicine, including Anusol suppositories. While the active ingredients are applied locally rather than absorbed systemically in significant amounts, professional guidance is important during pregnancy and breastfeeding. Your healthcare provider can recommend the safest option for your situation.

Are Anusol suppositories suitable for children?

Anusol suppositories are not recommended for children under 12 years of age. Haemorrhoids are uncommon in young children, and any rectal symptoms in this age group should be assessed by a GP to rule out other causes. For children aged 12 and over, the adult dose applies, but parental supervision is advised.

What are the side effects of Anusol suppositories?

Side effects are uncommon but may include mild local irritation, a temporary burning sensation, or — rarely — an allergic reaction such as redness or swelling around the anal area. If you experience a significant allergic reaction or worsening symptoms, stop use immediately and seek medical advice. Most people tolerate Anusol suppositories well when used as directed.

Can I use Anusol suppositories and Anusol cream at the same time?

If you have both internal and external haemorrhoids, it is possible to use Anusol suppositories for the internal symptoms and Anusol cream for external symptoms simultaneously. However, you should speak to your pharmacist before combining treatments to ensure this is appropriate for your specific situation. Avoid exceeding the recommended dose of either product.

What happens if I miss a dose of Anusol suppositories?

If you forget to use a suppository at the scheduled time, simply use it as soon as you remember — unless it is nearly time for your next dose, in which case skip the missed one. Do not use two suppositories at once to make up for a missed dose. Consistency helps, but missing an occasional dose is unlikely to significantly affect your recovery.

How long can I use Anusol suppositories for?

Anusol suppositories should not be used for more than 7 consecutive days without consulting a doctor. Prolonged use without medical review is not recommended, as persistent haemorrhoid symptoms may require further investigation or a different treatment approach. If your symptoms return after a short break, speak to your GP.

What are the alternatives to Anusol suppositories for piles?

Alternatives for internal haemorrhoids include other suppository-based products available from your pharmacist. For external symptoms, topical creams and ointments — such as those in our creams and ointments collection — may be more suitable. Your pharmacist can help you choose the right product based on whether your haemorrhoids are internal, external, or both.

Do I need a prescription for Anusol suppositories in the UK?

No, Anusol 12 Suppositories are classified as a general sale medicine in the UK, meaning you do not need a prescription to buy them. You can purchase them directly from Cured Pharmacy online without a GP appointment. This makes them a convenient option for managing haemorrhoid symptoms quickly and discreetly.

Can straining during bowel movements make haemorrhoids worse?

Yes — straining is one of the most common causes and aggravating factors for haemorrhoids. The NHS recommends increasing dietary fibre and fluid intake to soften stools and reduce the need to strain. If constipation is contributing to your symptoms, you may also find it helpful to explore our constipation collection for additional support.

What is the latest guidance on treating haemorrhoids at home?

Current NHS guidance recommends a combination of lifestyle changes — such as a high-fibre diet, adequate hydration, and avoiding prolonged sitting on the toilet — alongside OTC treatments like Anusol suppositories for piles to manage symptoms. For haemorrhoids that do not respond to self-care within a few weeks, referral for procedures such as banding may be considered. Always consult your GP if symptoms persist or worsen.

How Should You Use Anusol 12 Suppositories?

Using Anusol suppositories correctly ensures the active ingredients reach the affected area and work as intended. Always read the patient information leaflet before use, and follow these steps each time you use a suppository.

Try to avoid having a bowel movement for at least one hour after inserting the suppository, as this gives the ingredients time to be absorbed by the rectal tissue.

What Is the Correct Dose of Anusol 12 Suppositories?

Always use the lowest effective dose for the shortest time necessary. The table below summarises the recommended dosing for this product.

Do not use more than four suppositories in any 24-hour period. If you are unsure about the correct dose for your situation, speak to your pharmacist before starting treatment.

When Is the Best Time to Use Anusol Suppositories?

The most effective times to use Anusol suppositories are in the morning after waking, at night before bed, and after each bowel movement. Using them after a bowel movement is particularly important, as this is when the rectal area is most irritated and when the suppository can be retained for the longest period without interruption. Consistency matters — try to use them at the same times each day to maintain a steady level of symptom relief.

How Long Can You Use Anusol Suppositories For?

Anusol suppositories are intended for short-term use only. Do not use them for more than 7 consecutive days without consulting a doctor or pharmacist. If your symptoms have not improved within this time, or if they worsen at any point, stop treatment and seek medical advice. Persistent or recurrent haemorrhoids may require further investigation to rule out other underlying conditions. Lifestyle changes — such as increasing dietary fibre, drinking plenty of water, and avoiding prolonged sitting — can help prevent haemorrhoids from returning after treatment.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Anusol Suppositories?

Anusol suppositories are generally well tolerated when used as directed. The most commonly reported side effects are mild and localised to the area of application. These typically resolve on their own once treatment is stopped or the dose is reduced.

  • Mild burning or stinging sensation immediately after insertion
  • Temporary local discomfort or a feeling of pressure in the rectum
  • Minor irritation of the rectal mucosa

What Are the Less Common Side Effects of Anusol Suppositories?

Less commonly, some people may experience a reaction to one or more of the ingredients. These reactions are not typical but should be taken seriously if they occur.

  • Redness or rash around the anal area
  • Increased itching or swelling at the site of use
  • Skin sensitivity or contact dermatitis, particularly in those with a known sensitivity to Balsam Peru
  • Worsening of local irritation with prolonged use

What Are the Serious Side Effects of Anusol Suppositories?

Serious side effects are rare with this product. However, you should stop using Anusol suppositories immediately and seek urgent medical attention if you experience any of the following:

  • Signs of a severe allergic reaction, including significant swelling of the face, lips, or throat
  • Difficulty breathing or swallowing
  • A sudden worsening of rectal bleeding
  • Severe pain in the rectal or abdominal area

Rectal bleeding should always be assessed by a GP, particularly if it is new, heavy, or accompanied by a change in bowel habits. Do not assume all rectal bleeding is caused by haemorrhoids.

What Should You Do If You Experience Side Effects?

If you notice mild irritation or discomfort, try reducing the frequency of use and ensure you are inserting the suppository correctly. Mild side effects often settle within a day or two. If symptoms persist or worsen, stop using the product and speak to your pharmacist or GP. You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Anusol Suppositories Interact With Other Medicines?

No significant drug interactions are currently known for Anusol suppositories when used as directed. The active ingredients — zinc oxide, bismuth compounds, and Balsam Peru — are applied locally and are not significantly absorbed into the bloodstream at the doses used in this product. However, you should always inform your pharmacist of all medicines you are currently taking, including prescription medicines, over-the-counter products, and herbal supplements, before starting any new treatment.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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