Skip to product information
1 of 1

  • Images are for illustration purposes only

Anadin Original Pain Relief Tablets 16 Pack

Anadin Original Pain Relief Tablets 16 Pack

  • 1. Ozempic®️-equivalent therapy now available for weight management
  • 2. Average weight loss of 17%, with 1 in 3 patients achieving over 20%
  • 3. May help reduce osteoarthritis-related pain
  • 4. Wegovy®️ is not expected to impact the effectiveness of oral contraceptives
  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Relieves headaches, toothache, and period pain effectively
  • ✔️ Contains aspirin and caffeine for dual-action pain relief
  • ✔️ Suitable for adults and young people aged 16 and over
  • ✔️ Works within 30 to 60 minutes of taking a dose
  • ✔️ Convenient 16-tablet pack for everyday pain management

Price Checker

Regular price £1.65
Sale price £1.65
Sale Sold out
  • Lowest price guarantee
  • Includes FREE private prescription
View full details

 

What Are Anadin Original Tablets?

 

If you need fast, reliable relief from everyday aches and pains, Anadin Original tablets have been a trusted household name in the UK for decades. Each tablet contains aspirin 325 mg and caffeine 15 mg — a combination that targets mild to moderate pain while the caffeine is thought to give the aspirin a helping hand. At just £1.65 for a 16-pack, it's an accessible option for most medicine cabinets. You can browse the full range of options in our pain relief collection if you'd like to compare alternatives.

Aspirin has been used medicinally for well over a century, and its safety and efficacy profile is well established when used correctly in adults. Anadin Original is classified as a General Sale List (GSL) medicine in the UK, meaning it can be purchased without a prescription from pharmacies, supermarkets, and registered online pharmacies like Cured Pharmacy.

 

How Do Anadin Original Tablets Work?

 

Aspirin belongs to a class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It works by inhibiting enzymes called cyclo-oxygenase (COX-1 and COX-2), which are responsible for producing prostaglandins — chemicals in the body that trigger pain, inflammation, and fever. By reducing prostaglandin production, aspirin helps to ease the sensation of pain and lower a raised temperature.

  • Aspirin blocks COX enzymes, reducing prostaglandin synthesis
  • This lowers pain signals sent to the brain
  • Caffeine (15 mg per tablet) may enhance aspirin's analgesic effect
  • Onset of action is typically within 30–60 minutes of taking a dose

 

Who Should Use Anadin Original Tablets?

 

Anadin Original is suitable for adults and young people aged 16 and over who need short-term relief from mild to moderate pain. It's particularly useful for:

  • Headaches and migraines
  • Toothache and dental pain
  • Period pain (dysmenorrhoea)
  • Muscular aches, rheumatic pain, and neuralgia
  • Feverishness and the symptoms of colds and flu

It is not suitable for children under 16, people with aspirin or NSAID allergies, those with active peptic ulcers, or individuals with certain bleeding disorders. Always read the label before use.

 

How Do Anadin Original Tablets Compare to Paracetamol Tablets?

 

Feature Anadin Original Tablets Standard Paracetamol Tablets
Active ingredient Aspirin 325 mg + Caffeine 15 mg Paracetamol 500 mg
Anti-inflammatory action Yes (NSAID) No
Suitable for under 16s No Yes (age-appropriate dose)
Safe with stomach conditions Use with caution Generally yes

 

Is Anadin Original Suitable for Everyone?

 

Not quite. While Anadin Original tablets are widely available and effective for most healthy adults, there are important groups who should avoid them or seek advice first. People who are pregnant, breastfeeding, or have a history of stomach ulcers, kidney problems, or asthma triggered by NSAIDs should speak to a pharmacist or GP before use. If you're managing a long-term condition and looking for complementary health support, our vitamins and supplements collection may also be of interest.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Anadin Original Pain Relief Tablets 16 Pack specifications
Treatment category Pain relief / Analgesic
Mechanism of action COX enzyme inhibition reducing prostaglandin synthesis
Effective for Headache, toothache, period pain, muscular aches, fever
Suitable for Adults and young people aged 16 and over
Active ingredient Aspirin 325 mg, Caffeine 15 mg
Pack size 16 tablets
UK classification General Sale List (GSL)
Drug class NSAID (Non-steroidal anti-inflammatory drug)
Preparation Tablet
Route of administration Oral

Specifications of Anadin Original Pain Relief Tablets 16 Pack

 

What Is Anadin Original and What Is It Used For?

 

Anadin Original Pain Relief Tablets contain two active ingredients: aspirin 325 mg and caffeine 15 mg per tablet. Aspirin is an established analgesic and anti-inflammatory medicine used to relieve mild to moderate pain. The caffeine content is included at a low dose and is thought to complement aspirin's pain-relieving properties. This product is used for the short-term relief of headaches, toothache, period pain, neuralgia, rheumatic pain, muscular aches, and the feverishness associated with colds and flu.

 

What Do You Need to Know Before Using Anadin Original?

 

Before taking Anadin Original tablets, it's important to check whether this medicine is right for you. Do not take these tablets if any of the following apply:

  • You are allergic to aspirin, caffeine, or any other NSAIDs
  • You have or have had a stomach ulcer or gastrointestinal bleeding
  • You are under 16 years of age (risk of Reye's syndrome)
  • You have haemophilia or another bleeding disorder
  • You are in the third trimester of pregnancy
  • You have severe kidney, liver, or heart failure
  • You have asthma that is triggered by aspirin or other NSAIDs

The following medicines may interact with Anadin Original tablets. Always tell your pharmacist or GP what you are taking:

  • Anticoagulants such as warfarin or heparin
  • Other NSAIDs including ibuprofen or naproxen
  • Methotrexate (used for arthritis and some skin conditions)
  • Selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine
  • Antidiabetic medicines — aspirin may affect blood glucose levels
  • Corticosteroids — increased risk of gastrointestinal bleeding
  • Antacids — may affect how aspirin is absorbed

 

How Should You Use Anadin Original Tablets?

 

Always take Anadin Original exactly as described in the patient information leaflet. Do not exceed the stated dose. If you are unsure, ask your pharmacist for advice.

  1. Check you are not allergic to aspirin or any other ingredient listed on the pack
  2. Take 1 to 2 tablets with a full glass of water
  3. Swallow the tablets whole — do not crush or chew
  4. Take with or after food to reduce the risk of stomach irritation
  5. Wait at least 4 hours before taking your next dose
  6. Do not take more than 8 tablets in any 24-hour period
  7. Do not use for more than 3 days without speaking to a doctor
Indication Age Group Dose Frequency
Mild to moderate pain / fever Adults and young people 16+ 1–2 tablets Every 4 hours (max 8 tablets/24 hrs)
Children under 16 Under 16 Not suitable Do not use

 

What Are the Possible Side Effects of Anadin Original?

 

Like all medicines, Anadin Original can cause side effects, although not everyone experiences them. If you're also managing digestive discomfort alongside pain, you might find our indigestion collection helpful for supporting gut comfort.

Common side effects:

  • Stomach irritation or discomfort
  • Nausea
  • Indigestion

Less common side effects:

  • Gastrointestinal bleeding (black or tarry stools — seek urgent medical advice)
  • Allergic reactions including skin rash, itching, or swelling
  • Worsening of asthma symptoms in susceptible individuals
  • Tinnitus (ringing in the ears) — may indicate too high a dose
  • Prolonged bleeding time after cuts or injury

Stop taking Anadin Original and seek immediate medical attention if you experience signs of a serious allergic reaction, such as difficulty breathing, swelling of the face or throat, or a severe skin reaction.

 

How Should You Store Anadin Original Tablets?

 

Correct storage helps maintain the quality and safety of your tablets. If you're building a home first aid kit, our first aid collection has everything you might need alongside your pain relief essentials.

  • Store below 25°C in a dry place
  • Keep out of direct sunlight and away from moisture
  • Keep all medicines out of the sight and reach of children
  • Do not use after the expiry date printed on the pack
  • Do not store in a bathroom or near a sink — humidity can degrade the tablets
  • Dispose of unused medicines safely — return to your local pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Anadin Original tablets online in the UK?

You can buy Anadin Original Pain Relief Tablets 16 Pack directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £1.65. They are a General Sale List medicine, so no prescription is needed. You can also find them in supermarkets and high street pharmacies across the UK.

How do Anadin Original tablets work in the body?

Anadin Original tablets contain aspirin, which inhibits COX-1 and COX-2 enzymes, reducing the production of prostaglandins — chemicals that cause pain, inflammation, and fever. The small amount of caffeine (15 mg per tablet) is thought to enhance aspirin's analgesic effect. Together, they provide relief from mild to moderate pain within around 30 to 60 minutes.

How do I use Anadin Original tablets step by step?

Take 1 to 2 tablets with a full glass of water, ideally with or after food to protect your stomach. Allow at least 4 hours between doses and do not take more than 8 tablets in any 24-hour period. Always read the patient information leaflet before use.

What is the correct dose of Anadin Original for adults?

The recommended adult dose is 1 to 2 tablets every 4 hours when needed for pain relief. The maximum dose is 8 tablets in any 24-hour period. Do not use for more than 3 consecutive days without consulting a doctor or pharmacist.

What are the side effects of Anadin Original tablets?

The most common side effects include stomach irritation, nausea, and indigestion — taking the tablets with food can help reduce these. Less commonly, aspirin can cause gastrointestinal bleeding, allergic reactions, or worsening of asthma in susceptible individuals. Stop taking and seek medical advice if you notice black or tarry stools, difficulty breathing, or a severe skin reaction.

How do I manage stomach side effects from Anadin Original?

Taking Anadin Original tablets with food or a full glass of milk can help reduce stomach irritation. If you regularly experience indigestion or stomach discomfort with aspirin, speak to your pharmacist — they may suggest an alternative pain reliever. You can also explore our indigestion collection for products that may help ease digestive discomfort.

Who is eligible to take Anadin Original tablets?

Anadin Original is suitable for adults and young people aged 16 and over who need short-term relief from mild to moderate pain or fever. It is not suitable for children under 16, people allergic to aspirin or NSAIDs, those with stomach ulcers, or individuals with certain bleeding disorders. Pregnant women should consult their GP before use.

Can children take Anadin Original tablets?

No — Anadin Original tablets must never be given to anyone under 16 years of age. Aspirin use in children is associated with a rare but serious condition called Reye's syndrome, which can affect the brain and liver. For children's pain relief, speak to your pharmacist about age-appropriate alternatives such as paracetamol or ibuprofen suspensions.

What happens if I miss a dose of Anadin Original?

Anadin Original is taken as needed for pain rather than on a fixed schedule, so there is no "missed dose" in the traditional sense. Simply take your next dose when you need it, ensuring at least 4 hours have passed since your last dose. Never double up to make up for a missed dose.

Can I take Anadin Original tablets with other medicines?

Anadin Original can interact with several medicines, including warfarin, other NSAIDs like ibuprofen, SSRIs, methotrexate, and corticosteroids. These combinations can increase the risk of bleeding or other side effects. Always tell your pharmacist or GP about all medicines you are taking before starting Anadin Original.

Is Anadin Original safe to take during pregnancy?

Aspirin-containing products are generally not recommended during pregnancy, particularly in the third trimester, as they may affect the baby's circulation and delay labour. If you are pregnant or trying to conceive, always speak to your GP or midwife before taking any pain relief. They can advise on the safest option for you and your baby.

What are the alternatives to Anadin Original tablets?

Common alternatives include paracetamol tablets (suitable for a wider range of people, including those who cannot take aspirin) and ibuprofen tablets (another NSAID with anti-inflammatory properties). The right choice depends on your health history, other medicines, and the type of pain you're experiencing. Browse our pain relief collection to compare available options.

How long can you take Anadin Original tablets for?

Anadin Original is intended for short-term use only — no more than 3 consecutive days without medical advice. If your pain persists beyond this period, or if it worsens, you should consult your GP to rule out an underlying cause. Long-term use of aspirin without medical supervision can increase the risk of stomach problems and other complications.

Does the caffeine in Anadin Original tablets cause side effects?

Each Anadin Original tablet contains only 15 mg of caffeine — a very small amount compared to a cup of coffee (which typically contains around 80–100 mg). At this dose, caffeine-related side effects such as jitteriness or sleep disturbance are unlikely for most people. However, if you are sensitive to caffeine or avoiding it for health reasons, speak to your pharmacist before use.

What are the latest findings on aspirin for pain relief?

Aspirin remains a well-established and widely studied analgesic. Current NHS guidance confirms it is effective for mild to moderate pain in adults when used at the correct dose and for short periods. Ongoing research continues to explore aspirin's broader roles, but for everyday pain relief, the evidence supporting its use at standard OTC doses is well documented and consistent.

How Should You Use Anadin Original Tablets?

Anadin Original tablets are taken orally with a full glass of water. To reduce the chance of stomach irritation, it is best to take them with or shortly after food. Follow these steps each time you take a dose:

What Is the Correct Dose of Anadin Original Tablets?

The dose varies by age, and Anadin Original is only suitable for people aged 16 and over. Always use the lowest effective dose for the shortest time necessary to relieve your symptoms. The table below summarises the recommended dosing:

When Is the Best Time to Use Anadin Original Tablets?

Take Anadin Original as soon as your pain begins — early treatment tends to be more effective than waiting until discomfort becomes severe. Because aspirin can irritate the stomach lining, taking your dose with a meal or snack is always a sensible approach. Avoid taking tablets on an empty stomach where possible, and try not to take a dose too close to bedtime unless necessary, as the caffeine content may affect sleep in sensitive individuals.

How Long Can You Use Anadin Original Tablets For?

Anadin Original is designed for short-term use only. You should not take it for more than 3 consecutive days without speaking to a doctor or pharmacist. If your pain has not improved after 3 days, or if it worsens at any point, stop taking the tablets and seek medical advice. Prolonged use of aspirin without supervision can increase the risk of stomach problems, including ulcers and bleeding, so it is important not to use this product as a long-term solution without professional guidance.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)

What Are the Most Common Side Effects of Anadin Original Tablets?

Most people tolerate Anadin Original well when taken at the recommended dose, but some individuals do experience side effects. The most frequently reported ones relate to the digestive system, largely because aspirin can irritate the stomach lining. Taking your tablets with food or milk can help reduce these effects.

  • Stomach discomfort or pain
  • Nausea
  • Indigestion or heartburn
  • Mild stomach upset

What Are the Less Common Side Effects of Anadin Original Tablets?

Less commonly, some people may experience more noticeable reactions. These are not typical but are worth being aware of, particularly if you are taking aspirin for the first time or have a history of stomach problems.

  • Tinnitus (ringing in the ears) — this may suggest the dose is too high
  • Prolonged bleeding time after cuts or minor injuries
  • Skin rash or itching
  • Worsening of asthma symptoms in people sensitive to NSAIDs
  • Dizziness or headache (paradoxically, in some individuals)

What Are the Serious Side Effects of Anadin Original Tablets?

Serious side effects are uncommon but require immediate medical attention if they occur. Gastrointestinal bleeding is the most significant risk associated with aspirin use, particularly with prolonged or high-dose use. Signs include vomiting blood or passing black, tarry stools. Severe allergic reactions — known as anaphylaxis — are rare but can include swelling of the face, lips, or throat, difficulty breathing, and a sudden drop in blood pressure. Stop taking Anadin Original immediately and call 999 or go to your nearest A&E if you experience any of these symptoms.

What Should You Do If You Experience Side Effects of Anadin Original?

For mild side effects such as stomach discomfort, try taking your next dose with food and plenty of water. If side effects persist or concern you, stop taking the tablets and speak to your pharmacist or GP. You should never ignore symptoms such as unusual bruising, blood in your urine, or persistent abdominal pain — these warrant prompt medical review. Your pharmacist can also advise on whether an alternative pain reliever might be more suitable for you.

Can Anadin Original Tablets Interact With Other Medicines?

Yes — aspirin has a number of clinically significant interactions. Taking Anadin Original alongside anticoagulants such as warfarin significantly increases the risk of bleeding. Combining it with other NSAIDs like ibuprofen raises the risk of stomach ulcers and gastrointestinal bleeding. SSRIs (antidepressants such as fluoxetine or sertraline) combined with aspirin can also increase bleeding risk. Methotrexate toxicity may be increased when taken alongside aspirin. Always inform your pharmacist or GP of every medicine, supplement, or herbal remedy you are taking before starting Anadin Original.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

We’re a safe and
regulated UK service

Registered Pharmacy Badge

Lowest Price Guarantee

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

100% discreet packaging

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

Agent

Need help?
Talk to our friendly experts now

How our service works

Service Setup

Service setup

Discreet Packaging

Discreet packaging

Express Delivery

Express delivery