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Almus Ibuprofen and Codeine 200mg/12.8mg

Almus Ibuprofen and Codeine 200mg/12.8mg

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  • ✔️ Dual-action relief: ibuprofen and codeine target pain together
  • ✔️ Effective for dental, back, and period pain
  • ✔️ Works within 30–60 minutes of taking orally
  • ✔️ Suitable for adults when single analgesics have failed
  • ✔️ Pharmacy-only formula with codeine for moderate pain

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What Are Ibuprofen and Codeine Tablets Used For?

 

When everyday pain refuses to budge with a single painkiller, a combination approach can make a real difference. Ibuprofen and codeine tablets bring together two well-established analgesics — ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), and codeine phosphate, a mild opioid — into one tablet designed for short-term relief of moderate pain. Almus Ibuprofen and Codeine 200mg/12.8mg is a pharmacy-only (P) medicine available without a prescription, though it does require a pharmacist consultation before purchase.

This product is indicated for pain that has not responded adequately to ibuprofen or paracetamol alone. Think dental pain after an extraction, muscular aches, period pain, or back pain that's been lingering for a day or two. If you're already exploring our pain relief collection, you'll find this tablet sits firmly in the moderate-pain category — a step up from standard ibuprofen but still available over the counter when used correctly.

 

How Does Almus Ibuprofen and Codeine Work in the Body?

 

The two active ingredients work through entirely different mechanisms, which is precisely why combining them can be more effective than either alone.

  • Ibuprofen (200mg): Inhibits cyclo-oxygenase (COX-1 and COX-2) enzymes, reducing the production of prostaglandins — the chemical messengers responsible for inflammation, swelling, and pain sensitisation at the site of injury.
  • Codeine phosphate (12.8mg): Acts centrally on mu-opioid receptors in the brain and spinal cord, raising your pain threshold and altering the emotional perception of pain. Codeine is also partially converted to morphine in the liver via the CYP2D6 enzyme pathway.
  • Combined effect: Peripheral anti-inflammatory action from ibuprofen plus central analgesic action from codeine creates a broader pain-relief profile than either ingredient achieves independently.

Onset of action is typically within 30–60 minutes of taking the tablet orally with water.

 

Who Is Almus Ibuprofen and Codeine Suitable For?

 

This medicine is intended for adults and young people aged 18 and over who are experiencing moderate pain that has not been adequately controlled by ibuprofen or paracetamol used alone at the recommended dose. It is not a first-line painkiller — it's specifically for that step up in pain management.

It may be appropriate for you if you experience:

  • Dental pain or post-extraction discomfort
  • Moderate back pain or muscular pain
  • Dysmenorrhoea (period pain) that hasn't responded to standard ibuprofen
  • Headache or migraine where inflammation is a contributing factor

 

How Does Almus Ibuprofen and Codeine Compare to Standard Ibuprofen?

 

Feature Almus Ibuprofen & Codeine 200mg/12.8mg Standard Ibuprofen 400mg
Active ingredients Ibuprofen + Codeine phosphate Ibuprofen only
Pain level targeted Moderate pain unresponsive to single analgesic Mild to moderate pain
UK legal classification Pharmacy (P) medicine General Sale List (GSL)
Maximum duration of use 3 days without medical advice Up to 10 days for pain (with caution)
Risk of dependence Yes (codeine component) No

 

How Should You Store Almus Ibuprofen and Codeine Tablets?

 

Store your ibuprofen and codeine tablets below 25°C in a dry place, away from direct sunlight and moisture. Keep them in the original blister packaging until you're ready to use them, and always store them out of the reach and sight of children. Do not use the tablets after the expiry date printed on the pack — if in doubt, return them to your pharmacy for safe disposal.

Because this product contains codeine, it must be kept securely. Codeine-containing medicines should never be shared with others, even if their symptoms seem similar to yours. If you're managing multiple medicines at home, our first aid collection includes storage solutions and organisers that may help.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Almus Ibuprofen and Codeine 200mg/12.8mg specifications
Treatment category Analgesic / Pain relief
Mechanism of action NSAID (COX inhibition) + Opioid receptor agonist
Effective for Moderate pain unresponsive to single analgesics
Suitable for Adults and young people aged 18 and over
Active ingredient Ibuprofen 200mg, Codeine phosphate hemihydrate 12.8mg
Pack sizes 12 tablets, 24 tablets
Strengths 200mg / 12.8mg per tablet
UK classification Pharmacy (P) medicine
Drug class NSAID + Opioid analgesic combination
Preparation Film-coated tablet
Route of administration Oral

Specifications of Almus Ibuprofen and Codeine 200mg/12.8mg

 

What Is Almus Ibuprofen and Codeine and What Is It Used For?

 

Almus Ibuprofen and Codeine 200mg/12.8mg is a combination analgesic tablet containing two active ingredients: ibuprofen, an NSAID, and codeine phosphate hemihydrate, a mild opioid. It is used for the short-term relief of moderate pain in adults and young people aged 18 and over, specifically when that pain has not been adequately controlled by ibuprofen or paracetamol used alone. Common examples include dental pain, back pain, period pain, and muscular aches.

 

What Do You Need to Know Before Using Almus Ibuprofen and Codeine?

 

Do not take these tablets if any of the following apply to you:

  • You are allergic to ibuprofen, codeine, aspirin, or any other NSAID
  • You have or have had a peptic ulcer, gastrointestinal bleeding, or perforation
  • You have severe heart failure, severe kidney disease, or severe liver disease
  • You are in the third trimester of pregnancy
  • You are under 18 years of age
  • You are a known ultra-rapid metaboliser of codeine (CYP2D6 ultra-rapid metaboliser)
  • You are breastfeeding
  • You have a condition causing breathing difficulties, such as severe asthma

The following medicines may interact with Almus Ibuprofen and Codeine. Tell your pharmacist or doctor if you are taking:

  • Other NSAIDs (e.g. naproxen, aspirin at anti-inflammatory doses)
  • Anticoagulants (e.g. warfarin, heparin)
  • Monoamine oxidase inhibitors (MAOIs) — do not use within 14 days of stopping an MAOI
  • Selective serotonin reuptake inhibitors (SSRIs) — risk of serotonin syndrome
  • Other opioid-containing medicines or CNS depressants (including alcohol)
  • Antihypertensives and diuretics — ibuprofen may reduce their effectiveness
  • Lithium or methotrexate — ibuprofen can increase plasma levels

 

How Should You Use Almus Ibuprofen and Codeine Correctly?

 

Always take this medicine exactly as directed on the label or as advised by your pharmacist. Swallow the tablets whole with a full glass of water. Taking them with food or milk can help reduce the chance of stomach upset, which is a known risk with ibuprofen-containing products.

  1. Take 1 or 2 tablets with a full glass of water.
  2. Take with food or milk to protect your stomach.
  3. Leave at least 6 hours between doses.
  4. Do not take more than 6 tablets in any 24-hour period.
  5. Do not use for more than 3 consecutive days without speaking to a doctor or pharmacist.
  6. Do not crush or chew the tablets.
Indication Age Group Dose Frequency
Moderate pain (dental, back, period) Adults and young people 18+ 1–2 tablets Up to 3 times daily (every 6 hours)
Not suitable Under 18 years

 

What Are the Possible Side Effects of Almus Ibuprofen and Codeine?

 

Like all medicines, this product can cause side effects, though not everyone will experience them. If you're also managing other health conditions, it's worth browsing our indigestion collection — ibuprofen can sometimes irritate the stomach lining, and having a suitable antacid to hand is sensible.

  • Common side effects (may affect up to 1 in 10 people):
    • Nausea or vomiting
    • Constipation
    • Dizziness or light-headedness
    • Drowsiness
    • Stomach discomfort or indigestion
  • Less common side effects (may affect up to 1 in 100 people):
    • Headache
    • Skin rash or itching
    • Fluid retention (oedema)
    • Raised blood pressure
    • Confusion or mood changes

Stop taking the tablets and seek immediate medical attention if you experience: difficulty breathing or swallowing, severe stomach pain, black or bloody stools, swelling of the face or throat, or signs of a serious skin reaction such as blistering or peeling.

 

How Should You Store Almus Ibuprofen and Codeine Safely?

 

Correct storage protects both the medicine's effectiveness and the safety of those around you — particularly important with a codeine-containing product.

  • Store below 25°C in a dry place, away from direct heat and sunlight
  • Keep in the original blister pack until use
  • Store out of the reach and sight of children at all times
  • Do not use after the expiry date printed on the packaging
  • Do not dispose of medicines via household waste — return unused tablets to your pharmacy
  • Never share codeine-containing medicines with another person

If you're unsure whether this product is right for your pain, our pain relief collection includes a range of alternatives your pharmacist can help you compare.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Almus Ibuprofen and Codeine 200mg/12.8mg online in the UK?

You can buy Almus Ibuprofen and Codeine 200mg/12.8mg from Cured Pharmacy, a GPhC-registered online pharmacy. Because it contains codeine, it is a Pharmacy (P) medicine, so you'll need to complete a short clinical questionnaire before your order is approved. This ensures the product is appropriate for your situation and keeps you safe.

How do ibuprofen and codeine tablets work together in the body?

Ibuprofen works peripherally by blocking COX enzymes and reducing prostaglandin production, which lowers inflammation and pain at the site of injury. Codeine works centrally by binding to opioid receptors in the brain and spinal cord, raising your pain threshold. Together, they tackle pain from two different angles, which is why the combination can be more effective than either ingredient used alone.

How do I take Almus Ibuprofen and Codeine tablets step by step?

Take 1 to 2 tablets with a full glass of water, ideally with food or milk to protect your stomach. Leave at least 6 hours between each dose and do not take more than 6 tablets in 24 hours. Do not use for more than 3 consecutive days without speaking to a pharmacist or doctor.

What is the correct dose of Almus Ibuprofen and Codeine for adults?

The recommended dose for adults aged 18 and over is 1 to 2 tablets, taken up to three times a day with at least 6 hours between doses. The maximum daily dose is 6 tablets in any 24-hour period. Always use the lowest effective dose for the shortest time necessary.

When is the best time to take ibuprofen and codeine tablets?

There is no single "best" time of day — take the tablets when your pain is present and requires relief. However, always take them with food or a glass of milk to reduce the risk of stomach irritation from the ibuprofen component. Spacing doses evenly throughout the day (every 6–8 hours) helps maintain consistent pain control.

What are the common side effects of ibuprofen and codeine tablets?

The most commonly reported side effects include nausea, constipation, dizziness, drowsiness, and stomach discomfort. These are often mild and tend to improve as your body adjusts. Taking the tablets with food can help reduce stomach-related side effects in particular.

How do I manage side effects from Almus Ibuprofen and Codeine?

For nausea, try taking the tablets with a light meal rather than on an empty stomach. Constipation — a common effect of codeine — can often be managed by drinking plenty of water and eating a fibre-rich diet. If drowsiness is a problem, avoid driving or operating machinery until you know how the medicine affects you.

Who should not take Almus Ibuprofen and Codeine tablets?

This medicine is not suitable for anyone under 18, people with a known allergy to ibuprofen, aspirin, or codeine, those with active peptic ulcers, severe kidney or liver disease, or women who are pregnant (especially in the third trimester) or breastfeeding. People who are known CYP2D6 ultra-rapid metabolisers of codeine should also avoid this product due to the risk of rapid conversion to morphine at higher-than-expected levels.

What happens if I miss a dose of Almus Ibuprofen and Codeine?

If you miss a dose and it is not yet time for your next one, simply take the missed dose as soon as you remember — provided at least 6 hours have passed since your last dose. Never double up to compensate for a missed dose. If you are unsure, speak to your pharmacist for guidance.

Can I take Almus Ibuprofen and Codeine with paracetamol?

In general, ibuprofen and paracetamol can be taken together as they work through different mechanisms and do not interact directly. However, because this product already contains codeine, you should not take it alongside other codeine- or opioid-containing products, including co-codamol. Always check with your pharmacist before combining any medicines.

How long can you take ibuprofen and codeine tablets for?

These tablets are intended for short-term use only — a maximum of 3 consecutive days without medical supervision. Codeine carries a recognised risk of dependence and tolerance with prolonged use. If your pain has not improved after 3 days, you should consult your GP rather than continuing to self-medicate.

What are the alternatives to Almus Ibuprofen and Codeine tablets?

Alternatives include standard ibuprofen 400mg, paracetamol 500mg, co-codamol (paracetamol and codeine), or naproxen for inflammatory pain. The right choice depends on your pain type, medical history, and any other medicines you take. You can explore a range of options in our pain relief collection and speak to a pharmacist for personalised advice.

Is Almus Ibuprofen and Codeine suitable for period pain?

Yes — dysmenorrhoea (period pain) is one of the recognised indications for this product, particularly when standard ibuprofen alone has not provided sufficient relief. Ibuprofen is especially effective for period pain because prostaglandins play a key role in uterine cramping, and NSAIDs directly reduce their production. If period pain is a recurring issue, it's worth discussing longer-term management options with your GP.

Can I drink alcohol while taking ibuprofen and codeine tablets?

You should avoid alcohol while taking this medicine. Alcohol increases the sedative effects of codeine and can also worsen the risk of gastrointestinal bleeding associated with ibuprofen. Even small amounts of alcohol can amplify drowsiness and dizziness, making activities like driving particularly dangerous.

What are the latest guidelines on codeine-containing medicines in the UK?

The MHRA and NHS have issued guidance highlighting the risk of codeine dependence, particularly with prolonged use. Codeine-containing medicines are now restricted to adults aged 18 and over in the UK, and pack sizes available without prescription are limited. The NHS recommends using the lowest effective dose for the shortest possible time, and seeking medical advice if pain persists beyond 3 days. You can find further information on managing pain through our cold and flu collection for symptom-related discomfort, or speak directly to one of our pharmacists.

How Should You Use Almus Ibuprofen and Codeine?

Always read the patient information leaflet before taking this medicine and follow the instructions carefully. Swallow the tablets whole — do not crush or chew them. Taking them with food or a glass of milk significantly reduces the risk of stomach irritation, which is a known concern with ibuprofen-containing products.

What Is the Correct Dose of Almus Ibuprofen and Codeine?

The dose varies by age — this product is not suitable for anyone under 18 years of age. Always use the lowest effective dose for the shortest duration necessary to control your pain. If 1 tablet provides adequate relief, there is no need to take 2.

When Is the Best Time to Use Almus Ibuprofen and Codeine?

Take the tablets when pain is present and requires relief — there is no fixed time of day. However, spacing doses evenly (every 6 to 8 hours) throughout the day helps maintain more consistent pain control rather than waiting until pain becomes severe before taking the next dose. If you are prone to stomach sensitivity, taking your first dose of the day with breakfast is a practical approach.

Because codeine can cause drowsiness, be mindful of timing if you need to drive or operate machinery. Evening doses may be preferable if drowsiness is a concern during your working day.

How Long Can You Use Almus Ibuprofen and Codeine For?

This medicine is intended for short-term use only. Do not take it for more than 3 consecutive days without speaking to a doctor or pharmacist. Codeine carries a recognised risk of dependence and tolerance with prolonged use, and the MHRA advises that codeine-containing OTC medicines should not be used long-term without medical supervision.

If your pain persists beyond 3 days, worsens, or is accompanied by other symptoms, stop taking the tablets and consult your GP. Continuing to use codeine-containing medicines beyond the recommended duration can lead to physical dependence, even at the doses found in OTC products.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Almus Ibuprofen and Codeine?

Most people tolerate this medicine well when taken as directed, but side effects can occur. The most frequently reported ones relate to both the ibuprofen and codeine components. Taking the tablets with food and staying well hydrated can help reduce their severity.

  • Nausea or vomiting
  • Constipation
  • Dizziness or light-headedness
  • Drowsiness or sedation
  • Stomach discomfort, indigestion, or heartburn

What Are the Less Common Side Effects of Almus Ibuprofen and Codeine?

Less common side effects affect a smaller proportion of users but are still worth being aware of. If any of the following persist or become troublesome, speak to your pharmacist or GP.

  • Headache
  • Skin rash, itching, or hives
  • Fluid retention (swollen ankles or feet)
  • Raised blood pressure
  • Confusion, mood changes, or difficulty concentrating
  • Dry mouth
  • Sweating

What Are the Serious Side Effects of Almus Ibuprofen and Codeine?

Serious side effects are rare but require immediate medical attention. Stop taking the tablets straight away and call 999 or go to your nearest A&E if you experience any of the following:

  • Difficulty breathing, wheezing, or tightness in the chest (signs of bronchospasm or anaphylaxis)
  • Swelling of the face, lips, tongue, or throat
  • Severe stomach pain, black or tarry stools, or vomiting blood — these may indicate gastrointestinal bleeding
  • Severe skin reactions such as blistering, peeling, or a widespread rash
  • Signs of liver or kidney problems: yellowing of the skin or eyes, significantly reduced urination, or severe fatigue
  • Slow or shallow breathing (respiratory depression — a known risk with opioids)

What Should You Do If You Experience Side Effects?

For mild side effects such as nausea or constipation, simple measures — taking the tablets with food, drinking plenty of water, and eating a fibre-rich diet — are often sufficient. Drowsiness usually improves with time, but you should avoid driving or operating heavy machinery until you know how this medicine affects you.

If you experience any side effect that concerns you, or if a side effect does not improve, contact your pharmacist or GP. You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Almus Ibuprofen and Codeine Interact With Other Medicines?

Yes — this product has several clinically significant interactions. Ibuprofen can reduce the effectiveness of antihypertensives and diuretics, and can increase plasma levels of lithium and methotrexate to potentially toxic levels. Codeine interacts with MAOIs, SSRIs, and other CNS depressants including alcohol, increasing the risk of sedation and, in serious cases, serotonin syndrome or respiratory depression. Always inform your pharmacist of every medicine you are taking — including herbal remedies and supplements — before starting this product.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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