Skip to product information
1 of 1

  • Images are for illustration purposes only

Systane UD Lubricant Eye Drops Free

Systane UD Lubricant Eye Drops Free

  • 1. Ozempic®️-equivalent therapy now available for weight management
  • 2. Average weight loss of 17%, with 1 in 3 patients achieving over 20%
  • 3. May help reduce osteoarthritis-related pain
  • 4. Wegovy®️ is not expected to impact the effectiveness of oral contraceptives
  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Relieves dry, gritty, and irritated eyes on contact
  • ✔️ Preservative-free formula safe for frequent daily use
  • ✔️ Single-use vials eliminate contamination risk entirely
  • ✔️ Suitable for contact lens wearers and sensitive eyes
  • ✔️ Mimics natural tear film for lasting ocular comfort

Price Checker

Regular price £11.99
Sale price £11.99
Sale Sold out
  • Lowest price guarantee
  • Includes FREE private prescription
View full details

 

What Are Systane UD Preservative Free Eye Drops?

 

If your eyes feel gritty, tired, or persistently uncomfortable, you are not alone. Dry eye is one of the most common eye complaints seen in UK pharmacies and GP surgeries. Systane UD Lubricant Eye Drops Free are single-use, unit dose preservative free eye drops designed to relieve the discomfort of dry, irritated eyes quickly and gently. Each vial contains a sterile lubricating solution that mimics your natural tear film, helping to restore moisture and comfort to the ocular surface. You can browse our full range of eye care products if you are looking for additional support alongside these drops.

Dry eye syndrome affects millions of people in the UK and can be triggered by screen use, air conditioning, contact lens wear, certain medications, or simply ageing. Because Systane UD comes in individual vials with no preservatives added, it is particularly well suited to people who need to use eye drops frequently throughout the day.

 

How Do Systane UD Eye Drops Work?

 

The drops work by supplementing your natural tear film — the thin layer of fluid that keeps your eye surface lubricated and protected. When this film breaks down too quickly, you experience the hallmark symptoms of dry eye: burning, stinging, redness, and that persistent feeling of something in your eye.

  • Polyethylene glycol 400 (0.4%) and propylene glycol (0.3%) act as humectants, drawing moisture to the ocular surface and holding it there.
  • The solution forms a protective, gel-like coating over the cornea and conjunctiva, reducing friction with each blink.
  • The unit dose format means no preservatives are needed to maintain sterility — each vial is used once and discarded.
  • The drops are compatible with the eye's natural pH, minimising the risk of stinging on instillation.

 

Who Should Use Systane UD Eye Drops?

 

These drops are suitable for a wide range of people experiencing dry or uncomfortable eyes. They are especially useful if you have previously found preserved eye drops irritating, or if you use eye drops more than four times a day — at which point preservative-free options are generally recommended by eye care professionals.

  • Adults and older children with dry eye syndrome or ocular surface discomfort
  • Contact lens wearers (remove lenses before use; reinsert after 15 minutes)
  • People with sensitive eyes or a known sensitivity to preservatives
  • Those recovering from eye surgery, where preservative-free drops are often advised

 

How Do Systane UD Eye Drops Compare to Multi-Dose Alternatives?

 

Feature Systane UD (This Product) Typical Multi-Dose Eye Drops
Preservative-free Yes — each vial used once Usually no — contains preservatives
Suitable for frequent use (>4x daily) Yes Not always recommended
Risk of preservative-related irritation None Possible with prolonged use
Shelf life after opening Discard immediately after use Typically 28 days after opening

 

How Should You Store Systane UD Eye Drops?

 

Store Systane UD Lubricant Eye Drops Free below 25°C, away from direct sunlight and out of reach of children. Do not freeze the vials. Because these are preservative free eye drops in single-use format, each vial must be discarded immediately after use — even if solution remains. Using a vial more than once risks contamination and potential eye infection. If you wear contact lenses and are also managing other eye-related conditions, it is worth exploring our wider allergy and hay fever range, as allergic eye symptoms are often confused with dry eye.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Systane UD Lubricant Eye Drops Free specifications
Treatment category Dry eye / ocular lubricant
Mechanism of action Forms a lubricating film over the ocular surface to supplement natural tear film
Effective for Dry, irritated, or uncomfortable eyes
Suitable for Adults and children; contact lens wearers (remove before use); sensitive eyes
Active ingredient Polyethylene glycol 400 0.4%, propylene glycol 0.3%
Pack sizes 30 unit dose vials (0.4 ml each)
UK classification General Sale List (GSL)
Drug class Ocular lubricant
Preparation Sterile ophthalmic solution, preservative-free
Route of administration Topical ophthalmic (eye drops)

Specifications of Systane UD Lubricant Eye Drops Free

 

What Is Systane UD and What Is It Used For?

 

Systane UD Lubricant Eye Drops Free is a sterile, preservative-free ophthalmic solution supplied in single-use unit dose vials. It is used to relieve the symptoms of dry eye syndrome — a condition where the eyes do not produce enough tears, or where tears evaporate too quickly. Symptoms include dryness, grittiness, burning, stinging, redness, and a feeling of something in the eye. The NHS notes that dry eye is very common and can affect people of all ages, though it becomes more frequent with age and is more prevalent in women. Environmental factors such as prolonged screen use, air conditioning, central heating, and wind can all worsen symptoms.

These drops are also used to provide temporary relief from eye irritation caused by environmental exposure — such as dust, smoke, or chlorinated water. Because they are preservative free eye drops in a single-use format, they are particularly appropriate for people who need to use lubricating drops multiple times throughout the day.

 

What Do You Need to Know Before Using Systane UD?

 

Before using these drops, read the following carefully. Do not use Systane UD if any of the contraindications below apply to you.

Do not use if you:

  • Are allergic to polyethylene glycol 400, propylene glycol, or any other ingredient in the formulation
  • Have a known hypersensitivity to any component of the product
  • Are using the drops in a child under 2 years without medical advice

Warnings and precautions:

  • Remove contact lenses before instilling the drops; wait at least 15 minutes before reinserting
  • Do not touch the tip of the vial to your eye or any surface — this risks contamination
  • Discard each vial immediately after use, even if solution remains
  • If your symptoms do not improve after a few days, or if you experience pain, vision changes, or increased redness, stop use and consult a healthcare professional
  • Seek medical advice before use if you have had recent eye surgery

Drug interactions:

  • No clinically significant drug interactions are known for this product
  • If you are using other eye drops or eye ointments, wait at least 5 minutes between applications; apply ointments last

 

How Should You Use Systane UD Eye Drops?

 

Using these drops correctly ensures you get the most benefit and reduces the risk of contamination. Follow these steps each time you use a vial.

  1. Wash your hands thoroughly before handling the vial.
  2. Twist off the top of one unit dose vial.
  3. Tilt your head back slightly and look up.
  4. Gently pull down your lower eyelid to create a small pocket.
  5. Hold the vial above your eye and squeeze gently to instil one or two drops.
  6. Close your eye gently for a moment and blink a few times to spread the solution.
  7. Discard the vial immediately — do not store or reuse.
  8. Repeat in the other eye if needed.
Indication Age Group Dose Frequency
Dry eye / ocular lubrication Adults 1–2 drops per eye As needed throughout the day
Dry eye / ocular lubrication Children (2 years and over) 1–2 drops per eye As directed by a healthcare professional

 

What Are the Possible Side Effects of Systane UD?

 

Like all medicines, Systane UD can cause side effects, although not everyone experiences them. Because the formula is preservative-free, the risk of irritation is lower than with many preserved alternatives. If you are managing other eye-related conditions alongside dry eye, our eye care collection includes a range of products that may help.

Common side effects (may affect up to 1 in 10 people):

  • Temporary blurred vision immediately after instillation
  • Mild stinging or burning sensation on application

Less common side effects (may affect up to 1 in 100 people):

  • Eye redness or irritation
  • Sticky sensation around the eyelids
  • Watery eyes

Stop using the drops and seek medical advice if you experience eye pain, significant vision changes, or worsening redness that does not settle quickly.

 

How Should You Store Systane UD Eye Drops?

 

Correct storage helps maintain the sterility and effectiveness of the product. If you are also managing seasonal eye irritation, it may be worth looking at our allergy and hay fever range for complementary support.

  • Store below 25°C in a cool, dry place
  • Do not freeze
  • Keep out of direct sunlight
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the packaging
  • Discard each unit dose vial immediately after use — do not store opened vials
  • Do not use if the packaging is damaged or the solution appears cloudy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Systane UD Lubricant Eye Drops Free online in the UK?

You can buy Systane UD Lubricant Eye Drops Free directly from Cured Pharmacy online for £11.99 — no prescription required. We are a GPhC-registered UK online pharmacy, so you can order with confidence. Simply add to your basket and choose your preferred delivery option at checkout.

How do Systane UD eye drops work in the eye?

Systane UD eye drops work by forming a lubricating, protective film over the surface of the eye, supplementing your natural tear film. The active ingredients — polyethylene glycol 400 and propylene glycol — act as humectants, drawing moisture to the ocular surface and reducing friction with each blink. This helps relieve the dryness, grittiness, and discomfort associated with dry eye syndrome.

How do I use Systane UD eye drops step by step?

Wash your hands, then twist off the top of one unit dose vial. Tilt your head back, gently pull down your lower eyelid, and squeeze one or two drops into the eye. Close your eye gently, blink a few times, and then discard the vial immediately — never save an opened vial for later use, as this risks contamination.

How often can I use Systane UD eye drops each day?

Systane UD eye drops can be used as often as needed throughout the day to manage dry eye symptoms. Because they are preservative free eye drops, they are safe for frequent use without the risk of preservative-related irritation. If you find you need them very frequently or your symptoms are worsening, speak to your GP or optometrist.

Are Systane UD eye drops safe for contact lens wearers?

Yes, but you must remove your contact lenses before instilling the drops. Wait at least 15 minutes after using the drops before reinserting your lenses. Always follow the guidance of your optometrist, particularly if you wear rigid gas-permeable lenses or have been advised to limit lens wear due to dry eye.

Why should I choose preservative free eye drops over standard ones?

Preservatives such as benzalkonium chloride, commonly found in multi-dose eye drops, can cause or worsen ocular surface irritation with frequent use — particularly in people with sensitive eyes or those using drops more than four times daily. Preservative free eye drops eliminate this risk entirely, making them the preferred choice for long-term or frequent use. Eye care professionals routinely recommend them for people with dry eye syndrome.

What are the side effects of Systane UD eye drops?

Side effects are uncommon but may include temporary blurred vision immediately after instillation, mild stinging, or a brief sensation of irritation. These effects typically resolve within a minute or two. If you experience persistent pain, significant redness, or any change in vision, stop using the drops and seek advice from a pharmacist or GP.

Can I use Systane UD eye drops if I am pregnant or breastfeeding?

There is no specific evidence of harm from using ocular lubricants during pregnancy or breastfeeding, as systemic absorption from eye drops is minimal. However, as with any medicine, it is advisable to speak to your GP or midwife before use during pregnancy or whilst breastfeeding, to ensure it is appropriate for your individual circumstances.

What happens if I accidentally use too many drops?

Using more drops than needed is unlikely to cause serious harm, as the solution is a lubricant rather than a pharmacologically active drug. You may experience temporary blurred vision or a watery sensation. If you accidentally swallow the contents of a vial or experience any unexpected symptoms, contact NHS 111 or your nearest pharmacist for advice.

What are the alternatives to Systane UD eye drops?

Alternatives include other preservative-free lubricant eye drops such as HyloFort, Hyabak, Artelac Rebalance, and Blink Intensive Tears. You can explore a range of options in our eye care collection. Your pharmacist or optometrist can help you identify the most suitable product based on the severity of your symptoms and your lifestyle.

How long can I use Systane UD eye drops for?

Systane UD eye drops can be used on a long-term basis as needed to manage chronic dry eye symptoms. There is no set maximum duration of use for lubricant eye drops. However, if your symptoms persist or worsen despite regular use, it is important to see your GP or optometrist to investigate any underlying cause.

Who is eligible to use Systane UD eye drops?

Systane UD eye drops are suitable for adults and children aged 2 years and over who experience dry, irritated, or uncomfortable eyes. They are particularly well suited to people with sensitive eyes, frequent eye drop users, contact lens wearers, and those who have previously experienced irritation from preserved eye drops. Speak to a healthcare professional before use in young children.

Can Systane UD eye drops be used alongside other eye medications?

If you are using other eye drops or eye ointments alongside Systane UD, wait at least 5 minutes between each product. Always apply eye ointments last, as they can prevent other drops from being absorbed properly. If you are using prescription eye medications, check with your pharmacist or GP before adding any new eye drops to your routine.

What is the latest research on lubricant eye drops for dry eye?

Current clinical evidence supports the use of lubricant eye drops as a first-line treatment for mild to moderate dry eye syndrome. Research consistently shows that preservative-free formulations are better tolerated with long-term use compared to preserved alternatives, particularly in patients with ocular surface disease. The NHS recommends lubricating eye drops as the primary self-care measure for dry eye symptoms.

Do Systane UD eye drops interact with any medicines?

No clinically significant drug interactions are known for Systane UD Lubricant Eye Drops Free. Because the active ingredients are lubricants rather than pharmacological agents, the risk of systemic interaction is extremely low. If you are using multiple eye preparations, space them at least 5 minutes apart and apply any ointments last. If you take medicines that cause dry eyes as a side effect — such as antihistamines — you may also find it helpful to browse our allergy and hay fever range for additional support.

How Should You Use Systane UD Eye Drops?

Using Systane UD correctly is straightforward, but a few simple steps make a real difference to both comfort and safety. Always wash your hands before handling the vials, and never touch the tip of the vial to your eye or any other surface.

What Is the Correct Dose of Systane UD Eye Drops?

The dose is one to two drops per eye, instilled as often as needed to relieve symptoms. There is no fixed maximum number of daily applications for lubricant eye drops, but if you find yourself needing them very frequently, it is worth discussing this with your optometrist or GP to explore whether an underlying condition requires treatment.

When Is the Best Time to Use Systane UD Eye Drops?

There is no single "best" time — these drops are designed to be used whenever your eyes feel dry, uncomfortable, or irritated. Many people find them particularly helpful first thing in the morning, when eyes can feel especially dry after sleep, and again in the afternoon during prolonged screen use. If you wear contact lenses, use the drops before inserting your lenses in the morning (removing them first if already in) and again after removal in the evening if needed.

People who work in air-conditioned offices or spend long hours in front of screens often benefit from using a vial mid-morning and mid-afternoon as a preventative measure, rather than waiting until discomfort becomes significant.

How Long Can You Use Systane UD Eye Drops For?

Systane UD eye drops can be used on an ongoing, long-term basis as required to manage dry eye symptoms. Unlike some medicated eye drops, there is no recommended maximum treatment duration for lubricant eye drops. However, if your symptoms have not improved after a week of regular use, or if they worsen at any point, you should seek advice from your GP or optometrist to rule out an underlying condition such as blepharitis or meibomian gland dysfunction.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)

What Are the Most Common Side Effects of Systane UD Eye Drops?

Systane UD Lubricant Eye Drops Free are generally very well tolerated, particularly because they contain no preservatives. That said, as with any eye preparation, some people may notice mild effects immediately after instillation. These are usually brief and resolve on their own within a minute or two.

  • Temporary blurred vision immediately after instilling the drops
  • Mild stinging or burning sensation on application
  • A brief watery sensation in the eye

What Are the Less Common Side Effects of Systane UD Eye Drops?

Less commonly, some people may experience slightly more noticeable reactions. These are still generally mild and tend to settle quickly without any specific treatment. If they persist beyond a few minutes or recur with every use, it is worth speaking to a pharmacist.

  • Eye redness or irritation that does not settle quickly
  • A sticky or crusty sensation around the eyelids after use
  • Sensitivity to light (photophobia) — rare
  • Itching around the eye area

What Are the Serious Side Effects of Systane UD Eye Drops?

Serious side effects are very rare with lubricant eye drops. However, you should stop using the product immediately and seek medical attention if you experience any of the following, as they may indicate an allergic reaction or a separate eye condition requiring treatment.

  • Significant eye pain that does not resolve
  • Sudden or persistent changes in vision
  • Severe redness or swelling of the eye or surrounding tissue
  • Signs of an allergic reaction: rash, swelling of the face or throat, difficulty breathing

What Should You Do If You Experience Side Effects?

If you notice any mild side effects such as temporary blurring or brief stinging, these are expected and do not usually require any action. Simply wait a minute or two and they should resolve. If you experience persistent irritation, pain, or any of the serious effects listed above, stop using the drops straight away. Contact your pharmacist or GP for advice. In the case of a severe allergic reaction, call 999 or go to your nearest A&E immediately.

You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. This helps improve the safety monitoring of medicines for everyone.

Can Systane UD Eye Drops Interact With Other Medicines?

No clinically significant interactions between Systane UD and other medicines have been identified. Because the active ingredients are lubricants with minimal systemic absorption, the risk of interaction with oral or topical medicines is extremely low. If you are using other eye drops or eye ointments at the same time, leave at least 5 minutes between each product and always apply ointments last. If you are using prescription eye medications such as glaucoma drops or antibiotic eye drops, check with your pharmacist before adding any new eye preparation to your routine.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

We’re a safe and
regulated UK service

Registered Pharmacy Badge

Lowest Price Guarantee

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

100% discreet packaging

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

Agent

Need help?
Talk to our friendly experts now

How our service works

Service Setup

Service setup

Discreet Packaging

Discreet packaging

Express Delivery

Express delivery