Skip to product information
1 of 1

  • Images are for illustration purposes only

Solgar Ester-C Plus 500mg Vitamin C - 50 Capsules

Solgar Ester-C Plus 500mg Vitamin C - 50 Capsules

  • 1. Ozempic®️-equivalent therapy now available for weight management
  • 2. Average weight loss of 17%, with 1 in 3 patients achieving over 20%
  • 3. May help reduce osteoarthritis-related pain
  • 4. Wegovy®️ is not expected to impact the effectiveness of oral contraceptives
  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Buffered, non-acidic vitamin C — gentle on sensitive stomachs
  • ✔️ Supports normal immune function with 500mg calcium ascorbate
  • ✔️ Contains vitamin C metabolites to aid white blood cell uptake
  • ✔️ Suitable for vegetarians seeking daily vitamin C support
  • ✔️ 50 capsules per pack — over seven weeks' supply at one daily

Price Checker

Regular price £6.99
Sale price £6.99
Sale Sold out
  • Lowest price guarantee
  • Includes FREE private prescription
View full details

 

What Is Ester-C Vitamin C Supplement and How Can It Help You?

 

Vitamin C is one of the most widely recognised nutrients in the UK, and for good reason. It plays a central role in immune function, collagen formation, and protecting your cells from oxidative stress. The NHS confirms that vitamin C — also known as ascorbic acid — is an essential nutrient that the body cannot produce on its own, meaning you rely entirely on diet or supplementation to meet your daily needs. Solgar Ester-C Plus 500mg offers a buffered, non-acidic form of vitamin C that is designed to be gentler on the digestive system than standard ascorbic acid supplements. If you're looking to support your immunity or simply top up your intake, you'll find a wide range of options in our vitamins and supplements collection.

Each capsule delivers 500mg of calcium ascorbate — the active form of Ester-C vitamin C supplement — alongside naturally occurring vitamin C metabolites. These metabolites are thought to support the uptake and retention of vitamin C within white blood cells, which are central to your immune response. At just £6.99 for 50 capsules, this is a straightforward, cost-effective way to maintain adequate vitamin C levels throughout the year.

 

How Does Solgar Ester-C Plus 500mg Work in the Body?

 

Understanding how this supplement works helps you make an informed decision. Unlike standard ascorbic acid, Ester-C uses a patented manufacturing process that produces calcium ascorbate — a calcium salt of vitamin C — along with small amounts of vitamin C metabolites such as threonate, lyxonate, and xylonate.

  • Calcium ascorbate is absorbed in the small intestine and transported into the bloodstream.
  • The metabolites present in Ester-C are thought to facilitate uptake of vitamin C into white blood cells (leucocytes), where it is needed most for immune defence.
  • Because it is buffered with calcium, the pH is closer to neutral, making it significantly less acidic than standard ascorbic acid — reducing the risk of stomach irritation.
  • Vitamin C acts as an antioxidant, neutralising free radicals and supporting the regeneration of other antioxidants such as vitamin E.
  • It is also essential for the biosynthesis of collagen, L-carnitine, and certain neurotransmitters.

 

Who Should Consider Using Solgar Ester-C Plus 500mg?

 

This supplement is suitable for most healthy adults who want to maintain adequate vitamin C intake. It is particularly well suited to those who find standard vitamin C supplements cause digestive discomfort. People who smoke, have a restricted diet, or are recovering from illness may have higher vitamin C requirements, as the NHS notes that certain lifestyle factors can deplete vitamin C levels more quickly.

  • Adults with sensitive stomachs who cannot tolerate acidic vitamin C supplements
  • People looking to support their immune system during winter months or periods of stress
  • Those with diets low in fresh fruit and vegetables
  • Individuals who smoke, as smoking is associated with lower vitamin C levels

 

How Does Solgar Ester-C Compare to Standard Vitamin C Supplements?

 

Feature Solgar Ester-C Plus 500mg Standard Ascorbic Acid 500mg
Form Calcium ascorbate (buffered) Ascorbic acid (unbuffered)
Stomach friendliness Non-acidic, gentler on digestion Acidic, may cause irritation
Vitamin C metabolites Yes — threonate, lyxonate, xylonate No
Calcium content Yes (from calcium ascorbate) No

 

Is Solgar Ester-C Plus 500mg Suitable for Vegans and How Should It Be Stored?

 

Solgar Ester-C Plus 500mg capsules are suitable for vegetarians. However, if you follow a strictly vegan lifestyle, it is worth checking the current product label, as formulations can change. Store the capsules below 25°C in a cool, dry place away from direct sunlight. Keep the bottle tightly closed and out of reach of children. Do not use after the expiry date printed on the packaging.

If you are managing a long-term health condition or taking prescription medicines, it is always worth checking with your pharmacist before adding any new supplement to your routine. You might also find it helpful to explore our cold and flu range for additional immune support products during the winter season.

This product is a food supplement. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Solgar Ester-C Plus 500mg Vitamin C - 50 Capsules specifications
Treatment category Vitamins and supplements
Mechanism of action Antioxidant; supports collagen synthesis and immune function via ascorbate activity
Effective for Maintaining vitamin C levels; supporting immune function and collagen formation
Suitable for Adults; vegetarians; those with sensitive stomachs
Active ingredient Calcium ascorbate (Ester-C) 500mg
Pack size 50 capsules
Strength 500mg per capsule
UK classification Food supplement (not a licensed medicine)
Drug class Water-soluble vitamin
Preparation Capsule
Route of administration Oral

Specifications of Solgar Ester-C Plus 500mg Vitamin C - 50 Capsules

 

What Is Solgar Ester-C Plus 500mg and What Is It Used For?

 

Solgar Ester-C Plus 500mg is a food supplement containing calcium ascorbate — a buffered, non-acidic form of vitamin C. It is used to help maintain adequate vitamin C intake in adults who may not get enough from their diet alone. Vitamin C contributes to the normal function of the immune system, the protection of cells from oxidative stress, normal collagen formation for the function of skin, bones, cartilage, and blood vessels, and the reduction of tiredness and fatigue. The NHS advises that adults need 40mg of vitamin C per day, though requirements may be higher in certain circumstances such as illness, smoking, or restricted diet.

 

What Do You Need to Know Before Using Solgar Ester-C Plus 500mg?

 

Before taking this supplement, read the following carefully. Although Ester-C is generally well tolerated, there are some important considerations.

Do not take this supplement if you:

  • Have a known hypersensitivity to any of the ingredients
  • Have haemochromatosis (iron overload disorder) — vitamin C increases iron absorption
  • Have a history of kidney stones (calcium oxalate type) — high-dose vitamin C may increase oxalate excretion
  • Have glucose-6-phosphate dehydrogenase (G6PD) deficiency

Speak to your doctor or pharmacist before taking if you:

  • Are pregnant or breastfeeding
  • Have chronic kidney disease
  • Are due to have any medical tests — high-dose vitamin C can interfere with certain laboratory results

Possible interactions with other medicines:

  • Warfarin — vitamin C at high doses may affect anticoagulant control
  • Aluminium-containing antacids — vitamin C increases aluminium absorption
  • Oestrogen-containing medicines (including the combined oral contraceptive pill) — vitamin C may increase oestrogen levels
  • Statins — concurrent use with high-dose antioxidants may theoretically reduce efficacy in some studies, though evidence is limited

 

How Should You Use Solgar Ester-C Plus 500mg?

 

Always follow the label instructions or the advice of your pharmacist. This supplement is for oral use only.

  1. Take one capsule daily, or as directed by your healthcare professional.
  2. Swallow the capsule whole with a full glass of water.
  3. Take with food to minimise any risk of stomach discomfort.
  4. Do not open or crush the capsule unless advised to do so.
  5. Do not exceed the stated dose.
Indication Age Group Dose Frequency
General vitamin C supplementation Adults (18+) 1 capsule (500mg) Once daily
Not recommended Children under 18 Not applicable Seek paediatric advice

 

What Are the Possible Side Effects of Solgar Ester-C Plus 500mg?

 

Ester-C is considered gentler on the stomach than standard ascorbic acid, but side effects can still occur in some people. If you experience any severe or persistent symptoms, stop taking the supplement and speak to your pharmacist or GP.

Common side effects:

  • Mild gastrointestinal discomfort (bloating, nausea)
  • Loose stools or diarrhoea, particularly at higher doses
  • Heartburn in sensitive individuals

Less common side effects:

  • Headache
  • Flushing
  • Increased urinary oxalate excretion (relevant if you are prone to kidney stones)

If you experience signs of an allergic reaction — such as rash, swelling of the face or throat, or difficulty breathing — stop taking the supplement immediately and seek urgent medical attention. You can also browse our allergy and hay fever range if you are managing other allergic conditions alongside your supplement routine.

 

How Should You Store Solgar Ester-C Plus 500mg?

 

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and moisture
  • Keep the bottle tightly closed after each use
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the label
  • Do not store in the bathroom or near a heat source

Proper storage helps maintain the potency and quality of the supplement throughout its shelf life. If you notice any changes in colour, smell, or texture, do not use the product and dispose of it safely.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Solgar Ester-C Plus 500mg online in the UK?

You can buy Solgar Ester-C Plus 500mg directly from Cured Pharmacy, a GPhC-registered online pharmacy, for just £6.99 per pack of 50 capsules. It is available without a prescription and can be ordered conveniently from our vitamins and supplements collection. No GP referral is needed — simply add to basket and check out.

How does the Ester-C vitamin C supplement differ from regular vitamin C?

Ester-C uses calcium ascorbate rather than ascorbic acid, making it a buffered, non-acidic form of vitamin C that is gentler on the stomach. It also contains naturally occurring vitamin C metabolites — including threonate — which are thought to support uptake into white blood cells. This makes it a popular choice for people who find standard vitamin C supplements cause digestive discomfort.

How do I take Solgar Ester-C Plus 500mg step by step?

Taking this supplement is straightforward. Follow these steps:

  1. Take one capsule daily with a full glass of water.
  2. Take it with food to reduce any chance of stomach upset.
  3. Swallow the capsule whole — do not crush or chew.

Do not take more than the recommended dose unless advised by a healthcare professional.

What is the best time of day to take Solgar Ester-C Plus 500mg?

There is no strict requirement for a specific time of day, but taking it with a meal — such as breakfast or lunch — can help reduce the likelihood of any mild gastrointestinal discomfort. Consistency matters more than timing, so choose a time that fits easily into your daily routine. Taking it at the same time each day helps you remember your dose.

What are the side effects of Solgar Ester-C Plus 500mg and how do I manage them?

Most people tolerate Ester-C well, but some may experience mild gastrointestinal symptoms such as bloating, loose stools, or nausea — particularly if taken on an empty stomach. Taking the capsule with food usually resolves this. If symptoms persist or you experience anything more serious such as a rash or swelling, stop taking the supplement and contact your pharmacist or GP promptly.

Who is eligible to take Solgar Ester-C Plus 500mg?

This supplement is suitable for most healthy adults aged 18 and over, including vegetarians. It is particularly well suited to those with sensitive stomachs who cannot tolerate standard ascorbic acid supplements. It is not recommended for children without specific paediatric advice, and those with kidney disease, haemochromatosis, or G6PD deficiency should consult their doctor before use.

What happens if I miss a dose of Solgar Ester-C Plus 500mg?

If you forget to take your capsule, simply take it as soon as you remember — unless it is nearly time for your next dose, in which case skip the missed one and carry on as normal. Do not take a double dose to make up for a missed one. Missing an occasional dose of a daily supplement is unlikely to cause any harm.

Can I take Solgar Ester-C Plus 500mg if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, you should speak to your doctor or midwife before taking any vitamin C supplement, including this one. The NHS recommends that pregnant women get 40mg of vitamin C daily, which is usually achievable through a balanced diet. Higher supplemental doses during pregnancy should only be taken under medical supervision.

Does Solgar Ester-C Plus 500mg interact with any medicines?

Yes, vitamin C supplements can interact with certain medicines. Known interactions include warfarin (may affect anticoagulant control), aluminium-containing antacids (vitamin C increases aluminium absorption), and oestrogen-containing medicines such as the combined pill. Always tell your pharmacist about all supplements you are taking, especially if you are on prescription medication.

How long can I take Solgar Ester-C Plus 500mg for?

Solgar Ester-C Plus 500mg can be taken as part of an ongoing daily supplement routine for most healthy adults. There is no set maximum duration for supplementation at this dose level, but it is good practice to review your supplement use periodically with your pharmacist or GP — particularly if your diet or health circumstances change. Long-term use at very high doses is not recommended.

Is Solgar Ester-C Plus 500mg suitable for vegans?

Solgar Ester-C Plus 500mg capsules are suitable for vegetarians. If you follow a strictly vegan diet, check the current product label carefully, as formulations can occasionally change. Solgar does produce a range of vegan-friendly products, and you can explore further options in our vegan collection for supplements that meet vegan standards.

What are the alternatives to Solgar Ester-C Plus 500mg?

Alternatives include standard ascorbic acid tablets or capsules, liposomal vitamin C, and chewable vitamin C supplements. Standard ascorbic acid is widely available and lower in cost, but may cause more stomach irritation. Liposomal vitamin C is claimed to have higher bioavailability, though evidence is still emerging. The right choice depends on your digestive tolerance and personal preference.

Can Solgar Ester-C Plus 500mg help with colds and flu?

Vitamin C is well known for its role in supporting normal immune function, and regular supplementation may help reduce the duration or severity of common colds in some people, according to published research. However, it is not a cure for colds or flu. For additional support during cold and flu season, you may also want to browse our cold and flu range.

What does the research say about Ester-C vitamin C supplement absorption?

Some studies suggest that the vitamin C metabolites present in Ester-C — particularly threonate — may enhance uptake of vitamin C into white blood cells compared to standard ascorbic acid, though the overall clinical evidence base is still developing. The buffered nature of Ester-C is well established as reducing gastric acidity compared to unbuffered ascorbic acid. Always interpret supplement research critically and discuss with a healthcare professional if you have specific health goals.

How should I store Solgar Ester-C Plus 500mg to keep it effective?

Store your capsules in a cool, dry place below 25°C, away from direct sunlight and moisture. Keep the bottle tightly closed after each use and out of reach of children. Avoid storing in the bathroom, as humidity can degrade the supplement over time. Always check the expiry date on the label before use and discard any capsules that appear discoloured or have an unusual smell.

How Should You Use Solgar Ester-C Plus 500mg?

Solgar Ester-C Plus 500mg is designed for oral use and is straightforward to incorporate into your daily routine. Always read the product label before use and follow the instructions provided. If you have any questions, your pharmacist is the best person to ask.

What Is the Correct Dose of Solgar Ester-C Plus 500mg?

The recommended dose for adults is one capsule (500mg) per day. This provides 500mg of vitamin C as calcium ascorbate, which is well above the UK reference nutrient intake of 40mg per day for adults, making it suitable for those who want to actively supplement their intake. Do not take more than the stated dose without first speaking to a healthcare professional.

When Is the Best Time to Use Solgar Ester-C Plus 500mg?

You can take this supplement at any time of day that suits your routine. Most people find it easiest to take with breakfast or their main meal, as food helps buffer the capsule and reduces the chance of any mild stomach discomfort. Taking it at the same time each day also makes it easier to remember. There is no evidence that taking vitamin C at a specific time of day significantly affects its absorption or efficacy.

How Long Can You Use Solgar Ester-C Plus 500mg For?

Solgar Ester-C Plus 500mg can be taken as part of a long-term daily supplement routine for most healthy adults. There is no defined maximum duration at the 500mg daily dose, but it is sensible to review your supplement use with your pharmacist or GP at least once a year, or sooner if your health circumstances change. If you are taking it to address a specific deficiency, your doctor may advise a different approach once levels are restored.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)

What Are the Most Common Side Effects of Solgar Ester-C Plus 500mg?

Solgar Ester-C Plus 500mg is generally well tolerated, particularly because the buffered calcium ascorbate form is less acidic than standard vitamin C. That said, some people do experience mild digestive symptoms, especially when first starting supplementation or if taken on an empty stomach.

  • Mild nausea
  • Bloating or flatulence
  • Loose stools or diarrhoea (more likely at higher doses)
  • Mild stomach cramps

Taking the capsule with food usually reduces these effects significantly. If symptoms persist beyond a few days, speak to your pharmacist.

What Are the Less Common Side Effects of Solgar Ester-C Plus 500mg?

Less commonly, some individuals may notice the following effects, particularly if they are sensitive to vitamin C or taking higher doses than recommended.

  • Headache
  • Flushing or a feeling of warmth
  • Increased urinary frequency
  • Elevated urinary oxalate levels (relevant for those prone to calcium oxalate kidney stones)

What Are the Serious Side Effects of Solgar Ester-C Plus 500mg?

Serious side effects are rare at the 500mg daily dose. However, you should be aware of the following and seek medical attention promptly if they occur. Signs of an allergic reaction — such as skin rash, itching, swelling of the face, lips, or throat, or difficulty breathing — require immediate medical attention. In individuals with haemochromatosis, vitamin C supplementation can worsen iron overload, which is a serious condition requiring medical management.

What Should You Do If You Experience Side Effects of Solgar Ester-C Plus 500mg?

If you experience mild side effects such as nausea or loose stools, try taking the capsule with a larger meal or reducing your dose temporarily. If symptoms are more severe or do not resolve, stop taking the supplement and contact your pharmacist or GP. You can also report suspected side effects of food supplements to the Food Standards Agency (FSA) or seek advice from NHS 111.

Can Solgar Ester-C Plus 500mg Interact With Other Medicines?

Yes. Vitamin C supplements can interact with several medicines, and it is important to inform your pharmacist or doctor of everything you are taking. Key interactions to be aware of include warfarin — where high-dose vitamin C may affect anticoagulant control — aluminium-containing antacids, where vitamin C increases aluminium absorption, and oestrogen-containing medicines such as the combined oral contraceptive pill. Vitamin C may also interfere with certain laboratory blood and urine tests, so inform your doctor if you are taking this supplement before any tests.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

We’re a safe and
regulated UK service

Registered Pharmacy Badge

Lowest Price Guarantee

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

100% discreet packaging

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

Agent

Need help?
Talk to our friendly experts now

How our service works

Service Setup

Service setup

Discreet Packaging

Discreet packaging

Express Delivery

Express delivery