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Priligy Tablets

Priligy Tablets

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  • ✔️ Licensed dapoxetine tablet for premature ejaculation in men
  • ✔️ Clinically shown to increase ejaculatory latency two to three times
  • ✔️ On-demand dosing — only take it when needed
  • ✔️ Available in 30mg and 60mg strengths for tailored treatment
  • ✔️ Suitable for adult men aged 18 to 64 with PE

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Want to Buy Priligy Online Safely?

 

Premature ejaculation is more common than many men realise. In fact, it affects roughly one in three men at some point in their lives, making it the most prevalent male sexual dysfunction in the UK. If you've been struggling with it, you're far from alone — and there is a licensed treatment available. Buy Priligy online through a GPhC-registered pharmacy and you'll receive a clinically evaluated, prescription-only tablet designed specifically for this condition. Priligy is the only oral medicine licensed in the UK for premature ejaculation, and it's available here at Cured Pharmacy following a straightforward online consultation. You can also explore our wider range of men's health products if you're looking for additional support.

Priligy contains the active ingredient dapoxetine hydrochloride. It belongs to a class of medicines called selective serotonin reuptake inhibitors (SSRIs), though unlike standard antidepressant SSRIs, it's short-acting — meaning it works quickly and leaves your system within hours. It's taken on demand, not daily, which suits many men who prefer not to commit to a regular medication routine.

 

How Does Priligy Work to Delay Ejaculation?

 

Dapoxetine works by modulating serotonin signalling in the central nervous system. Serotonin plays a key role in regulating the ejaculatory reflex — and by inhibiting its reuptake, Priligy effectively raises serotonin levels at the nerve synapse, slowing down the reflex and giving you greater control. Here's a simplified breakdown of the mechanism:

  • Dapoxetine is absorbed rapidly after oral ingestion, reaching peak plasma concentration within one to two hours.
  • It inhibits the serotonin transporter (SERT), preventing serotonin from being reabsorbed too quickly.
  • Elevated synaptic serotonin delays the ejaculatory reflex via spinal and supraspinal pathways.
  • The effect is temporary — dapoxetine has a short half-life and is largely eliminated within 24 hours.

Clinical studies have shown that dapoxetine can increase intravaginal ejaculatory latency time (IELT) — the time from penetration to ejaculation — by two to three times compared to placebo. That's a meaningful difference for men who previously ejaculated within a minute or less.

 

Who Is Priligy Suitable For?

 

Priligy is licensed for adult men aged 18 to 64 who experience premature ejaculation. To be considered suitable, you should have had the condition for at least six months, and it should be causing you personal distress or relationship difficulties. It's not a lifestyle product — it's a clinically indicated treatment for a recognised medical condition.

You may be a good candidate for Priligy if:

  • You consistently ejaculate within one to two minutes of penetration.
  • You have little or no control over when you ejaculate.
  • The condition is causing you anxiety, frustration, or relationship strain.
  • You have no contraindicated medical conditions (see Section 2 for full details).

It is not suitable for men under 18 or over 64, those with significant cardiovascular disease, a history of syncope (fainting), or those currently taking serotonergic medicines such as SSRIs or MAOIs.

 

How Does Priligy Compare to Other Premature Ejaculation Treatments?

 

Feature Priligy (Dapoxetine) Topical Anaesthetic Spray/Cream
Form Oral tablet Topical application
How it works Modulates serotonin signalling Reduces penile sensitivity locally
Prescription required? Yes No (some products)
Onset of action 1–2 hours 5–15 minutes
Partner sensation affected? No Possibly, if not washed off

 

Is Priligy Stored and Used Correctly?

 

Priligy tablets should be stored below 30°C in their original blister packaging, away from moisture and direct sunlight. Keep them out of reach of children at all times. Do not use tablets past the expiry date printed on the pack. Each tablet is taken orally with a full glass of water — swallow it whole, do not crush or chew it. Taking it with food may help reduce nausea, which is one of the more commonly reported side effects.

If you're managing other aspects of your health alongside premature ejaculation — for example, if stress or anxiety is a contributing factor — it may be worth exploring our sleep aid range, as poor sleep can worsen anxiety and sexual performance concerns.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Priligy Tablets specifications
Treatment category Premature ejaculation
Active ingredient Dapoxetine hydrochloride
Strengths 30mg, 60mg
Pack sizes 3 tablets, 6 tablets
Mechanism of action Short-acting selective serotonin reuptake inhibitor (SSRI)
Route of administration Oral
UK classification Prescription Only Medicine (POM)
Drug class SSRI (short-acting)
Preparation Film-coated tablet
Suitable for Adult men aged 18–64 with premature ejaculation
Effective Increases time to ejaculation; clinical evidence supports use

Specifications of Priligy Tablets

 

What Is Priligy and What Is It Used For?

 

Priligy is a prescription-only medicine containing dapoxetine hydrochloride. It is licensed in the UK for the treatment of premature ejaculation (PE) in adult men aged 18 to 64. Premature ejaculation is defined clinically as ejaculation that occurs with minimal stimulation, typically within one to two minutes of penetration, and which causes significant personal distress. Priligy is taken on demand — meaning you take it only when you plan to have sexual activity, rather than every day.

 

What Do You Need to Know Before Using Priligy?

 

Before taking Priligy, it's essential to be aware of the following contraindications and warnings. This is not an exhaustive list — always complete a full medical consultation before starting treatment.

Do not take Priligy if you:

  • Are allergic to dapoxetine or any other ingredient in the tablet.
  • Have significant heart problems, including heart failure or arrhythmias.
  • Have a history of fainting (syncope) or blackouts.
  • Are taking monoamine oxidase inhibitors (MAOIs) or have taken them within the past 14 days.
  • Are taking other SSRIs, SNRIs, tricyclic antidepressants, or thioridazine.
  • Have moderate or severe liver impairment.
  • Are under 18 or over 64 years of age.

Known drug interactions — avoid combining Priligy with:

  • MAOIs (e.g. phenelzine, tranylcypromine) — risk of serotonin syndrome.
  • SSRIs or SNRIs (e.g. fluoxetine, venlafaxine) — increased serotonergic effects.
  • Tramadol, triptans, or lithium — serotonin syndrome risk.
  • CYP3A4 inhibitors such as ketoconazole or ritonavir — may increase dapoxetine levels.
  • Phosphodiesterase-5 inhibitors (e.g. sildenafil) — may increase risk of low blood pressure.
  • Alcohol — significantly increases risk of dizziness and fainting.

 

How Should You Use Priligy Correctly?

 

Always follow the instructions given by your prescribing clinician. The steps below reflect standard guidance, but your individual prescription may differ.

  1. Take one Priligy tablet one to three hours before anticipated sexual activity.
  2. Swallow the tablet whole with a full glass of water (at least 240ml).
  3. Taking it with food may reduce the likelihood of nausea.
  4. Sit or lie down for a short period after taking the tablet to reduce the risk of dizziness or fainting.
  5. Do not take more than one tablet in any 24-hour period.
  6. Do not take Priligy if you do not intend to have sexual activity within the next few hours.
Indication Age Group Starting Dose Maximum Dose
Premature ejaculation 18–64 years 30mg (taken 1–3 hours before activity) 60mg per 24 hours (if 30mg tolerated but insufficient)

If the 30mg dose is well tolerated but does not provide adequate benefit, your doctor may increase the dose to 60mg. Do not increase the dose yourself without medical advice. For men who find sexual health support beneficial alongside treatment, our condoms and sexual health range may also be of interest.

 

What Are the Possible Side Effects of Priligy?

 

Like all medicines, Priligy can cause side effects, though not everyone experiences them. The most important thing to know is that dizziness and fainting can occur — particularly when standing up quickly. Always sit or lie down after taking your tablet, especially the first time.

Common side effects (affecting more than 1 in 10 users):

  • Nausea
  • Dizziness
  • Headache
  • Diarrhoea

Less common side effects (affecting 1 in 10 to 1 in 100 users):

  • Insomnia or disturbed sleep
  • Anxiety or agitation
  • Dry mouth
  • Sweating
  • Blurred vision
  • Low blood pressure (hypotension) or fainting (syncope)
  • Erectile dysfunction (reported in some users)

If you experience fainting, severe dizziness, or any signs of serotonin syndrome (such as agitation, confusion, rapid heart rate, or muscle twitching), stop taking Priligy and seek medical attention immediately.

 

How Should You Store Priligy?

 

  • Store below 30°C.
  • Keep in the original blister packaging to protect from moisture.
  • Do not store in a bathroom or near a sink.
  • Keep out of the sight and reach of children.
  • Do not use after the expiry date printed on the pack.
  • Do not dispose of medicines via wastewater or household waste — return unused tablets to your pharmacy.

If you're managing your overall wellbeing alongside this treatment, you might find our vitamins and supplements range a useful complement to your health routine.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Priligy online in the UK?

You can buy Priligy online in the UK through a GPhC-registered online pharmacy such as Cured Pharmacy. A short online consultation is required to confirm your suitability before a prescription is issued and the medication is dispensed. This ensures the treatment is safe and appropriate for you specifically.

How does Priligy work in the body?

Priligy contains dapoxetine, a short-acting selective serotonin reuptake inhibitor (SSRI). It works by increasing serotonin activity at nerve synapses, which delays the ejaculatory reflex and extends the time to ejaculation. Unlike standard SSRIs used for depression, dapoxetine is absorbed and eliminated quickly, making it suitable for on-demand use.

How do I use Priligy step by step?

Follow these steps each time you take Priligy:

  1. Take one tablet one to three hours before planned sexual activity.
  2. Swallow whole with a full glass of water — do not crush or chew.
  3. Sit or lie down briefly after taking it to reduce dizziness risk.
  4. Do not take more than one tablet in 24 hours.

Always follow the specific instructions given by your prescribing clinician.

What is the correct dose of Priligy for premature ejaculation?

The recommended starting dose is 30mg, taken one to three hours before sexual activity. If the 30mg dose is well tolerated but does not provide sufficient benefit, your doctor may increase this to 60mg. Never increase the dose yourself without medical advice, and never take more than one tablet in any 24-hour period.

When is the best time to take Priligy?

Priligy should be taken one to three hours before you plan to have sexual activity. This timing allows the dapoxetine to reach its peak concentration in your bloodstream. Taking it with food may help reduce nausea, which is one of the more commonly reported side effects.

How do I manage the side effects of Priligy?

The most common side effects — nausea, dizziness, and headache — can often be minimised by taking Priligy with food and a large glass of water, and by sitting or lying down for a short while after taking it. Avoid alcohol entirely, as it significantly worsens dizziness and the risk of fainting. If side effects are persistent or severe, speak to your prescribing clinician about adjusting your dose.

Who is eligible to take Priligy tablets?

Priligy is licensed for adult men aged 18 to 64 who have experienced premature ejaculation for at least six months and find it causes personal distress or relationship difficulties. It is not suitable for men with significant cardiovascular disease, a history of fainting, liver impairment, or those taking serotonergic medicines such as SSRIs or MAOIs. A medical consultation is required to confirm eligibility.

Can I drink alcohol while taking Priligy?

No — alcohol should be avoided when taking Priligy. Combining alcohol with dapoxetine significantly increases the risk of dizziness, low blood pressure, and fainting. It can also impair your judgement and reaction time, making the experience unsafe. This is one of the most important safety warnings associated with this medicine.

What happens if I miss a dose of Priligy?

Because Priligy is taken on demand rather than on a daily schedule, there is no concept of a "missed dose" in the traditional sense. Simply take it one to three hours before your next planned sexual activity. Never take two tablets to make up for a missed occasion, and never take more than one tablet in 24 hours.

What are the alternatives to Priligy for premature ejaculation?

Alternatives include topical anaesthetic products (such as lidocaine-based sprays or creams), behavioural techniques like the squeeze or stop-start method, and psychological therapy or couples counselling. You can explore some relevant options in our condoms and sexual health range. A GP or sexual health specialist can advise on the most appropriate approach for your situation.

How long do you stay on Priligy?

Priligy is not intended for indefinite long-term use. Your doctor will typically review your response after four weeks of use to assess whether it is working and whether you are tolerating it well. Treatment duration varies depending on individual response and whether underlying psychological factors are also being addressed through therapy or other means.

Does Priligy affect fertility or testosterone levels?

There is no established evidence that dapoxetine affects fertility or testosterone levels when used as directed. However, if you have concerns about fertility or hormonal health, it is always worth discussing these with your GP before starting any new medication. Priligy acts on serotonin pathways rather than hormonal ones.

Can I take Priligy with erectile dysfunction medication?

Caution is required if you are considering taking Priligy alongside phosphodiesterase-5 inhibitors such as sildenafil (Viagra) or tadalafil (Cialis). The combination may increase the risk of low blood pressure and dizziness. Always inform your prescribing clinician of all medicines you are currently taking before starting Priligy.

What are the latest studies on dapoxetine for premature ejaculation?

Clinical trials have consistently shown that dapoxetine increases intravaginal ejaculatory latency time (IELT) by approximately two to three times compared to placebo. Studies published in peer-reviewed journals confirm improvements in ejaculatory control, sexual satisfaction, and reduced personal distress. Dapoxetine remains the only oral medicine specifically licensed for premature ejaculation in the UK and across much of Europe.

Is Priligy available on the NHS?

Priligy is not routinely available on NHS prescription in England for premature ejaculation. It is typically obtained through private prescription via a GP, sexual health clinic, or a regulated online pharmacy such as Cured Pharmacy. If you're looking for broader men's health support, our men's health collection includes a range of relevant products and treatments.

How Should You Use Priligy?

Priligy is taken on demand, meaning you only take it when you plan to have sexual activity — not every day. Always follow the instructions given by your prescribing clinician, and read the patient information leaflet supplied with your medication before use.

What Is the Correct Dose of Priligy?

The starting dose for all eligible men is 30mg. Your doctor will review your response after a period of use and may increase the dose to 60mg if the lower dose is well tolerated but not providing sufficient benefit. Never adjust your dose without medical guidance.

When Is the Best Time to Use Priligy?

Take Priligy one to three hours before you anticipate having sexual activity. This window allows dapoxetine to reach its peak plasma concentration, giving you the best chance of benefit. Avoid taking it too far in advance or immediately before activity, as timing affects how well it works.

Do not take Priligy more than once in a 24-hour period, even if you plan to have sexual activity more than once. If you experience dizziness after taking the tablet, remain seated or lying down until the feeling passes.

How Long Can You Use Priligy For?

Priligy is not intended for indefinite use. Your prescribing clinician will typically review your treatment after approximately four weeks to assess whether it is working and whether you are tolerating it well. If premature ejaculation persists despite treatment, or if you experience troublesome side effects, discuss this with your doctor promptly.

Some men use Priligy alongside psychological therapy or behavioural techniques, which may address underlying causes and reduce the need for ongoing medication over time. Long-term use should always be supervised by a healthcare professional.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Priligy?

Most men who take Priligy tolerate it reasonably well, but side effects do occur. The most frequently reported ones are related to the serotonergic activity of dapoxetine and its effects on blood pressure. Knowing what to expect can help you manage them effectively.

  • Nausea — the most commonly reported side effect; taking the tablet with food can help.
  • Dizziness — sit or lie down after taking Priligy to reduce this risk.
  • Headache
  • Diarrhoea

What Are the Less Common Side Effects of Priligy?

Less common side effects affect between 1 in 10 and 1 in 100 users. These are generally mild to moderate in severity but should be monitored, particularly when starting treatment or changing dose.

  • Insomnia or disturbed sleep
  • Anxiety or agitation
  • Dry mouth
  • Excessive sweating
  • Blurred vision
  • Low blood pressure (hypotension)
  • Fainting or near-fainting (syncope)
  • Erectile dysfunction
  • Fatigue or somnolence

What Are the Serious Side Effects of Priligy?

Serious side effects are rare but require immediate medical attention if they occur. The most significant risk is syncope (fainting), which can happen particularly when standing up quickly after taking the tablet. This is why sitting or lying down after ingestion is strongly recommended.

Serotonin syndrome is a rare but potentially serious condition that can occur if Priligy is taken alongside other serotonergic medicines. Symptoms include agitation, confusion, rapid heart rate, high temperature, muscle twitching, and loss of coordination. If you experience any of these, stop taking Priligy and seek emergency medical care immediately.

Can Priligy Interact With Other Medicines?

Yes — Priligy has several clinically significant drug interactions. Do not take it alongside MAOIs, SSRIs, SNRIs, tricyclic antidepressants, tramadol, triptans, or lithium, as these combinations increase the risk of serotonin syndrome. CYP3A4 inhibitors such as ketoconazole or ritonavir can raise dapoxetine blood levels, increasing side effect risk. Phosphodiesterase-5 inhibitors (e.g. sildenafil) may increase the risk of low blood pressure when combined with Priligy. Always disclose all medicines — including herbal remedies and supplements — to your prescribing clinician before starting treatment.

What Should You Do If You Experience Side Effects of Priligy?

If you experience mild side effects such as nausea or headache, these often improve with subsequent doses and can be managed by taking the tablet with food and water. For dizziness, remain seated or lying down until it passes. If you faint, experience chest pain, or develop symptoms of serotonin syndrome, stop taking Priligy immediately and seek urgent medical attention. You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

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Content last updated: 31 Mar 2025

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