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Preparation H Ointment - 25g

Preparation H Ointment - 25g

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  • ✔️ Relieves haemorrhoid itching, burning, and discomfort effectively
  • ✔️ Contains phenylephrine HCl to reduce swelling around the anus
  • ✔️ Shark liver oil soothes and protects irritated anal tissue
  • ✔️ Suitable for both internal and external haemorrhoid symptoms
  • ✔️ Compact 25g tube for discreet, convenient at-home use

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What Is Haemorrhoid Ointment and How Can It Help You?

 

Haemorrhoids — more commonly called piles — are swollen blood vessels inside or around the back passage. They affect a significant number of people in the UK at some point in their lives, causing itching, burning, soreness, and sometimes bleeding. If you're dealing with that uncomfortable, nagging irritation, you're certainly not alone. Haemorrhoid ointment is one of the most widely used over-the-counter options for managing these symptoms quickly and conveniently at home. Preparation H Ointment 25g is available from our haemorrhoids and piles collection for just £6.99, without the need for a prescription.

Preparation H Ointment contains two active ingredients: shark liver oil (3%) and phenylephrine hydrochloride (0.25%). These work together to soothe irritated tissue, reduce swelling, and create a protective barrier over the affected area. It's a trusted name in haemorrhoid care and has been used by patients for decades to manage both internal and external symptoms.

 

How Does Preparation H Ointment Work on Piles?

 

Understanding how this ointment works can help you use it more confidently. The two active ingredients each play a distinct role:

  • Shark liver oil (3%): Acts as a skin protectant. It helps soothe and moisturise the delicate tissue around the anal area, reducing irritation and supporting the skin's natural barrier function.
  • Phenylephrine hydrochloride (0.25%): A mild vasoconstrictor. It causes the small blood vessels in the area to narrow slightly, which helps reduce swelling and the sensation of fullness or discomfort associated with haemorrhoids.
  • Combined effect: Together, these ingredients address the itch, burn, and swelling that make haemorrhoids so uncomfortable day to day.

The ointment is applied directly to the affected area, where it gets to work locally. It doesn't enter the bloodstream in any meaningful quantity at the recommended dose, which is why it's considered safe for short-term OTC use in most adults.

 

Who Should Use Preparation H Ointment?

 

This ointment is designed for adults and young people aged 12 and over who are experiencing the typical symptoms of haemorrhoids. It's particularly useful if you're looking for fast-acting, localised relief without needing to visit your GP. That said, it's not right for everyone — so it's worth checking the list below before you buy.

Preparation H Ointment may be suitable if you:

  • Are aged 12 or over and experiencing itching, burning, or discomfort around the back passage
  • Have been previously diagnosed with haemorrhoids and recognise your symptoms
  • Need short-term relief while making lifestyle changes such as increasing fibre intake and fluid consumption
  • Prefer a topical ointment over suppositories or oral treatments

It is not suitable for children under 12. If you are pregnant, breastfeeding, or have a known allergy to any of the ingredients, speak to your pharmacist or GP before use.

 

How Does Preparation H Ointment Compare to Other Haemorrhoid Treatments?

 

Feature Preparation H Ointment 25g Anusol Cream
Active ingredients Shark liver oil, Phenylephrine HCl Zinc oxide, Bismuth oxide, Peru balsam
Vasoconstrictor included Yes (phenylephrine HCl) No
Suitable for internal use Yes (with applicator) Yes (with applicator)
OTC availability Yes Yes

 

Is Preparation H Ointment Suitable for Long-Term Use and How Should You Store It?

 

This haemorrhoid ointment is intended for short-term use only — no longer than 7 days without medical advice. If your symptoms persist beyond a week, or if you notice rectal bleeding, a change in bowel habits, or unexplained weight loss, you should see your GP promptly. These could be signs of something that needs further investigation. If you're managing ongoing digestive discomfort alongside your haemorrhoid symptoms, you might also find our IBS and cramps collection helpful.

Store Preparation H Ointment below 25°C, away from direct heat and sunlight. Keep the tube tightly closed when not in use, and always keep it out of the reach and sight of children. Do not use after the expiry date printed on the packaging.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Preparation H Ointment 25g specifications
Treatment category Haemorrhoids and piles
Mechanism of action Skin protectant and vasoconstrictor
Effective for Itching, burning, swelling, and discomfort from haemorrhoids
Suitable for Adults and children aged 12 and over
Active ingredients Shark liver oil 3%, Phenylephrine hydrochloride 0.25%
Pack size 25g tube
UK classification General Sale Medicine (GSL)
Drug class Topical vasoconstrictor / skin protectant
Preparation Ointment
Route of administration Topical / rectal

Specifications of Preparation H Ointment 25g

 

What Is Preparation H Ointment and What Is It Used For?

 

Preparation H Ointment 25g is an over-the-counter topical medicine used to relieve the symptoms of haemorrhoids (piles). Haemorrhoids occur when the blood vessels in and around the rectum and anus become swollen and inflamed. According to the NHS, they are very common and affect people of all ages, though they are more frequent in adults. Symptoms can include itching, burning, soreness, swelling, and discomfort — particularly after a bowel movement.

This ointment is used to provide localised symptomatic relief. It does not cure haemorrhoids, but it can make day-to-day life considerably more comfortable while your body heals. Lifestyle changes — such as eating more fibre, drinking plenty of fluids, and avoiding straining on the toilet — remain an important part of managing piles alongside any topical treatment.

 

What Do You Need to Know Before Using Preparation H Ointment?

 

Before applying this ointment, it's important to check whether it's appropriate for you. Do not use Preparation H Ointment if any of the following apply:

  • You are under 12 years of age
  • You are allergic to shark liver oil, phenylephrine hydrochloride, or any other ingredient listed in the patient information leaflet
  • You are pregnant or breastfeeding — speak to your GP or midwife first, as phenylephrine may not be suitable
  • You have rectal bleeding that has not been diagnosed by a doctor
  • You have a condition affecting your blood pressure or cardiovascular system, without first consulting your GP

Drug interactions at topical doses are not well documented, but you should still inform your pharmacist if you are taking:

  • Monoamine oxidase inhibitors (MAOIs) — phenylephrine may interact with these medicines
  • Other medicines for high blood pressure or heart conditions
  • Any other topical preparations applied to the same area

 

How Should You Use Preparation H Ointment?

 

Always use this ointment exactly as described in the patient information leaflet. If you're unsure about anything, ask your pharmacist. Here's a step-by-step guide to applying it correctly:

  1. Wash your hands thoroughly with soap and water before and after application.
  2. Clean the affected area gently with mild soap and warm water, then pat dry with a soft cloth.
  3. Squeeze a small amount of ointment (approximately 2.5cm) onto your fingertip or a clean piece of tissue.
  4. Apply gently to the external anal area, covering the affected skin.
  5. For internal haemorrhoids, attach the applicator nozzle to the tube and carefully insert it into the rectum before squeezing a small amount of ointment inside.
  6. Remove the applicator and wash it thoroughly after each use.
  7. Wash your hands again once you have finished.
Indication Age Group Dose Frequency
External haemorrhoids Adults and children 12+ Small amount (~2.5cm) Up to 4 times daily
Internal haemorrhoids Adults and children 12+ Small amount via applicator Up to 4 times daily
Children under 12 Not applicable Do not use Do not use

If you're also managing constipation — a common trigger for haemorrhoids — you may find it helpful to explore our constipation range alongside this treatment.

 

What Are the Possible Side Effects of Preparation H Ointment?

 

Like all medicines, Preparation H Ointment can cause side effects, although not everyone experiences them. Most people tolerate it well when used as directed.

Common side effects may include:

  • Mild local irritation or stinging at the site of application
  • Temporary redness or warmth around the treated area

Less common side effects may include:

  • Skin rash or contact dermatitis
  • Increased sensitivity or discomfort after application
  • Allergic reaction — symptoms may include rash, itching, swelling, or difficulty breathing

If you experience any signs of a serious allergic reaction — such as swelling of the face, lips, tongue, or throat, or difficulty breathing — stop using the ointment immediately and seek emergency medical help. If side effects are mild but persistent, stop use and speak to your pharmacist.

 

How Should You Store Preparation H Ointment?

 

Correct storage helps maintain the quality and safety of this medicine. Follow these guidelines:

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and sources of heat
  • Keep the tube tightly closed when not in use
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the tube or carton
  • Do not dispose of medicines via wastewater or household waste — return unused medicines to your pharmacist

For a broader range of topical treatments for skin and body concerns, you can also browse our creams and ointments collection at Cured Pharmacy.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Preparation H Ointment online in the UK?

You can buy Preparation H Ointment 25g directly from Cured Pharmacy, a UK GPhC-registered online pharmacy, for just £6.99. No prescription is needed as it is an over-the-counter medicine. Simply visit our haemorrhoids and piles collection and add it to your basket. It's a quick, discreet way to get the relief you need without visiting a GP or high street pharmacy.

How does Preparation H Ointment work in the body?

Preparation H Ointment works locally at the site of application rather than being absorbed into the bloodstream in significant amounts. Shark liver oil acts as a skin protectant, soothing and moisturising irritated tissue around the anal area. Phenylephrine hydrochloride is a mild vasoconstrictor that narrows the small blood vessels in the area, helping to reduce swelling and the discomfort associated with haemorrhoids. The two ingredients work together to address itching, burning, and soreness.

How do I use Preparation H Ointment step by step?

Start by washing your hands and the affected area with mild soap and warm water, then pat dry. Apply a small amount of ointment (around 2.5cm) to the external anal area up to four times daily — particularly in the morning, at night, and after each bowel movement. For internal haemorrhoids, attach the applicator nozzle to the tube, insert it gently into the rectum, and squeeze a small amount of ointment inside before removing and cleaning the applicator thoroughly.

What is the correct dose of Preparation H Ointment?

The recommended dose for adults and children aged 12 and over is a small amount of ointment applied to the affected area up to four times daily. Do not apply more than directed, as this will not speed up relief and may increase the risk of side effects. Always follow the instructions in the patient information leaflet supplied with the product.

When is the best time to use Preparation H Ointment?

The most effective times to apply Preparation H Ointment are in the morning, at night before bed, and after each bowel movement. Applying after a bowel movement is particularly important as this is when the area is most irritated and vulnerable. Consistent use at these times helps maintain a protective barrier and keeps symptoms under control throughout the day.

How long can you use Preparation H Ointment for?

Preparation H Ointment should not be used for more than 7 consecutive days without seeking medical advice. If your symptoms have not improved after a week, or if they worsen at any point, you should speak to your GP. Prolonged use without medical review is not recommended, as persistent haemorrhoid symptoms may require further investigation or a different treatment approach.

What are the side effects of Preparation H Ointment and how do I manage them?

Most people use Preparation H Ointment without experiencing any side effects. However, some people may notice mild local irritation, stinging, or redness at the application site. If you develop a skin rash, increased discomfort, or any signs of an allergic reaction — such as swelling of the face or difficulty breathing — stop using the ointment immediately and seek medical attention. For mild irritation, reducing the frequency of application and ensuring the area is clean and dry before use can help.

Who is eligible to use Preparation H Ointment?

Preparation H Ointment is suitable for adults and young people aged 12 and over who are experiencing symptoms of haemorrhoids such as itching, burning, or swelling. It is not suitable for children under 12. People who are pregnant, breastfeeding, or have cardiovascular conditions should speak to their GP or pharmacist before use, as phenylephrine hydrochloride may not be appropriate in these circumstances.

Can I use Preparation H Ointment during pregnancy?

Haemorrhoids are very common during pregnancy due to increased pressure on the pelvic blood vessels. However, you should speak to your GP or midwife before using Preparation H Ointment while pregnant or breastfeeding, as phenylephrine hydrochloride — one of the active ingredients — may not be considered safe in pregnancy. Your healthcare provider can recommend a suitable alternative if needed.

What happens if I accidentally use too much Preparation H Ointment?

Using slightly more than the recommended amount on one occasion is unlikely to cause serious harm, as the ointment works locally and is not significantly absorbed into the bloodstream. However, if you or someone else has accidentally swallowed any of the ointment, contact NHS 111 or your nearest A&E immediately. Always keep medicines out of the reach of children to prevent accidental ingestion.

What are the alternatives to Preparation H Ointment for piles?

There are several other over-the-counter haemorrhoid treatments available, including Anusol cream, Germoloids ointment, and haemorrhoid suppositories. Each product has a slightly different formulation, so the best choice depends on your specific symptoms and preferences. You can browse the full range of options in our haemorrhoids and piles collection, or ask your pharmacist for personalised advice.

Does Preparation H Ointment help with bleeding haemorrhoids?

Preparation H Ointment is designed to relieve itching, burning, and swelling — it is not specifically indicated to treat bleeding. If you notice rectal bleeding, you should see your GP before using any over-the-counter treatment, as bleeding from the back passage can sometimes have causes other than haemorrhoids that need to be ruled out. The NHS advises that unexplained rectal bleeding should always be assessed by a doctor.

Can Preparation H Ointment interact with other medicines?

At the recommended topical dose, significant drug interactions are unlikely. However, phenylephrine hydrochloride may interact with monoamine oxidase inhibitors (MAOIs) and certain medicines used for high blood pressure or heart conditions. Always tell your pharmacist about all medicines you are currently taking — including herbal remedies and supplements — before starting a new treatment.

How long does it take for Preparation H Ointment to work?

Many people notice some relief from itching and discomfort relatively quickly after applying Preparation H Ointment, often within the first day or two of use. The vasoconstrictor phenylephrine hydrochloride begins to reduce swelling shortly after application. Full symptomatic improvement typically occurs over several days of consistent use alongside lifestyle measures such as increasing dietary fibre and staying well hydrated.

What are the latest findings on topical haemorrhoid treatments?

Current NHS guidance continues to recommend topical treatments containing vasoconstrictors and skin protectants as a first-line option for symptomatic relief of mild to moderate haemorrhoids. Lifestyle modifications — particularly increasing fibre intake and fluid consumption — remain central to both treatment and prevention. If conservative measures and OTC treatments fail, procedures such as rubber band ligation or surgical haemorrhoidectomy may be considered by a specialist. If you're also managing related digestive symptoms, our constipation range may offer additional support.

How Should You Use Preparation H Ointment?

Using Preparation H Ointment correctly makes a real difference to how well it works. Always wash your hands before and after application, and make sure the affected area is clean and dry before you begin. Follow these steps each time you apply the ointment:

Always read the patient information leaflet supplied with the product before use. If you have any questions about how to apply the ointment, your pharmacist will be happy to help.

What Is the Correct Dose of Preparation H Ointment?

The correct dose depends on your age and the type of haemorrhoids you are treating. Do not apply more than the recommended amount — using extra ointment will not improve results and may increase the risk of side effects. The table below summarises the recommended dosing:

When Is the Best Time to Use Preparation H Ointment?

Timing your applications thoughtfully can help you get the most from this treatment. The most beneficial times to apply Preparation H Ointment are in the morning when you wake up, at night before bed, and after each bowel movement. Applying after a bowel movement is particularly important, as this is when the anal area is most irritated and the protective barrier provided by the ointment is most needed. Consistent, regular application at these key times helps maintain symptom control throughout the day and night.

How Long Can You Use Preparation H Ointment For?

Preparation H Ointment is intended for short-term use only. You should not use it for more than 7 consecutive days without seeking advice from your GP or pharmacist. If your symptoms have not improved within a week, or if they worsen at any point during treatment, stop using the ointment and consult a healthcare professional. Persistent or recurrent haemorrhoids may require further investigation or a different treatment approach, so it's always worth getting checked out if things aren't improving as expected.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Preparation H Ointment?

Most people who use Preparation H Ointment do not experience any side effects when it is applied as directed. However, as with any topical medicine, some people may notice mild reactions at the site of application. These are generally short-lived and resolve on their own once your skin adjusts.

  • Mild stinging or burning sensation immediately after application
  • Temporary redness or warmth around the treated area
  • Slight discomfort during the first few applications

What Are the Less Common Side Effects of Preparation H Ointment?

Less commonly, some people may experience a more noticeable skin reaction. If any of the following occur and persist, stop using the ointment and speak to your pharmacist or GP.

  • Contact dermatitis — a localised skin rash or inflammation
  • Increased itching or irritation after application
  • Dry or flaking skin around the application site
  • Heightened sensitivity to touch in the treated area

What Are the Serious Side Effects of Preparation H Ointment?

Serious side effects from Preparation H Ointment are rare but can occur, particularly if you have a sensitivity to any of the active ingredients. Phenylephrine hydrochloride, while used at a low topical dose, is a vasoconstrictor and should be used with caution in people with cardiovascular conditions. Seek urgent medical attention if you experience any of the following:

  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Severe skin rash or hives spreading beyond the application site
  • Chest tightness or palpitations (rare, particularly if large amounts are absorbed)

What Should You Do If You Experience Side Effects of Preparation H Ointment?

If you notice mild irritation or redness, try reducing the frequency of application and ensure the area is thoroughly clean and dry before each use. Avoid applying the ointment to broken or heavily inflamed skin. If side effects are moderate or do not settle within a day or two, stop using the product and consult your pharmacist. For any signs of a serious allergic reaction, stop use immediately and call 999 or go to your nearest A&E. You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Preparation H Ointment Interact With Other Medicines?

At the recommended topical dose, clinically significant drug interactions are uncommon. However, phenylephrine hydrochloride may interact with monoamine oxidase inhibitors (MAOIs) — a type of antidepressant — and with certain medicines used to treat high blood pressure or heart conditions. If you are taking any prescription medicines, herbal remedies, or supplements, always inform your pharmacist before starting Preparation H Ointment. Do not use this ointment alongside other topical preparations applied to the same area without first seeking advice.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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