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Paingone Plus

Paingone Plus

  • 1. Ozempic®️-equivalent therapy now available for weight management
  • 2. Average weight loss of 17%, with 1 in 3 patients achieving over 20%
  • 3. May help reduce osteoarthritis-related pain
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  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Drug-free TENS technology targets localised pain directly
  • ✔️ Suitable for back pain, joints, muscles, and arthritis
  • ✔️ Compact pen-style design — no wires or electrode pads
  • ✔️ Delivers up to 30 electrical pulses per pain-relief session
  • ✔️ Reusable device for long-term daily pain management

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Is Paingone Plus a TENS Pain Relief Device?

 

Living with persistent pain — whether it's a nagging lower back, stiff joints, or aching muscles — can wear you down over time. Paingone Plus is a handheld, drug-free electrotherapy device designed to offer an accessible alternative for people who want to manage everyday pain without reaching for tablets. It works by delivering transcutaneous electrical nerve stimulation (TENS) directly to the painful area, making it a practical option for those exploring pain relief beyond conventional medicines.

Chronic and recurrent pain affects millions of people across the UK. The NHS recognises TENS as a non-invasive method that some people find helpful for managing pain, particularly musculoskeletal conditions. Paingone Plus puts that technology into a compact, easy-to-use pen-style device — no wires, no electrode pads, no complicated setup required.

 

How Does Paingone Plus Work to Relieve Pain?

 

The science behind Paingone Plus is rooted in the gate control theory of pain. When the device is pressed against the skin and activated, it emits a small, controlled electrical pulse. This pulse travels through the skin and along nerve fibres, effectively competing with pain signals trying to reach the brain. Think of it as closing a "gate" on the pain pathway.

There are two key mechanisms at play:

  • Nerve signal interference: The electrical stimulation activates large-diameter nerve fibres, which can block or reduce the transmission of pain signals from smaller pain-carrying fibres.
  • Endorphin release: Repeated stimulation may encourage the body to release endorphins — its natural pain-modulating chemicals — which can provide a longer-lasting sense of relief.
  • No systemic absorption: Because Paingone Plus is a physical device rather than a medicine, there is no drug entering your bloodstream, which means no risk of drug interactions or systemic side effects.

 

Who Should Consider Using Paingone Plus?

 

Paingone Plus is designed for adults who experience localised, recurrent, or chronic pain and are looking for a drug-free management option. It may be particularly useful if you prefer to avoid or reduce your reliance on oral pain medicines, or if you're already taking other medications and want to minimise the risk of interactions.

It may be suitable for people with:

  • Joint pain, including knee and hip discomfort
  • Lower back pain or muscle stiffness
  • Arthritis-related aching
  • Sports injuries or post-exercise soreness
  • Shoulder, neck, or elbow pain

If you're managing a longer-term condition, it's worth exploring our electrical health and diagnostic range for complementary devices that support your wellbeing at home.

 

How Does Paingone Plus Compare to a Traditional TENS Machine?

 

Feature Paingone Plus Traditional TENS Machine
Electrode pads required No Yes
Portability Highly portable — pen-style Bulkier, requires leads
Ease of use Single-button operation Multiple settings to adjust
Treatment area Targeted, localised point Broader area coverage

 

Is Paingone Plus Clinically Suitable and How Should It Be Stored?

 

The TENS pain relief device format of Paingone Plus makes it accessible for most adults, but it is not appropriate for everyone. You should not use it if you have a cardiac pacemaker, an implanted defibrillator, or any other active implanted electronic device. It should also be avoided during pregnancy unless a healthcare professional has specifically advised otherwise. Do not apply the device over the eyes, throat, or broken skin.

Store Paingone Plus in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children. The device is battery-operated, so check the battery level regularly to ensure consistent pulse delivery. If you notice any change in the sensation produced by the device, replace the battery before continuing use.

This product is a medical device. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Paingone Plus specifications
Treatment category Alternative and drug-free pain relief
Mechanism of action Transcutaneous electrical nerve stimulation (TENS)
Effective for Joint pain, muscle aches, back pain, arthritis discomfort
Suitable for Adults seeking drug-free pain management
Active ingredient None — electrotherapy device
UK classification Medical device (non-prescription)
Preparation Handheld pen-style electrotherapy device
Route of administration Transcutaneous (applied to skin surface)

Specifications of Paingone Plus

 

What Is Paingone Plus and What Is It Used For?

 

Paingone Plus is a handheld, drug-free electrotherapy device that uses transcutaneous electrical nerve stimulation (TENS) to help manage localised pain. It is intended for adults who experience musculoskeletal pain — such as back pain, joint aches, arthritis discomfort, or sports-related muscle soreness — and who want a non-pharmacological option to complement their pain management routine.

Unlike oral pain medicines, Paingone Plus does not introduce any active chemical substance into your body. It works entirely through physical electrical stimulation of the skin and underlying nerve fibres. The NHS acknowledges TENS as a method some people find helpful for short-term pain relief, particularly for conditions like back pain and joint pain.

 

What Do You Need to Know Before Using Paingone Plus?

 

Before using Paingone Plus, it is important to check whether it is appropriate for your individual circumstances. This device is not suitable for everyone.

Do not use Paingone Plus if you:

  • Have a cardiac pacemaker or implanted cardioverter defibrillator (ICD)
  • Have any other active implanted electronic medical device
  • Are pregnant (unless specifically advised by a healthcare professional)
  • Have epilepsy
  • Have a known heart condition — seek medical advice first
  • Have broken, irritated, or infected skin at the intended application site
  • Are under 18 years of age

Additional warnings:

  • Do not apply over the eyes, throat, or front of the neck
  • Do not use while driving or operating machinery
  • Do not use in or near water
  • Avoid use directly over tumours or malignant tissue

Device interactions to be aware of:

  • May interfere with implanted electronic devices including pacemakers and neurostimulators
  • No known interactions with oral medicines — as a physical device, it does not affect drug metabolism

 

How Should You Use Paingone Plus?

 

Using Paingone Plus correctly is straightforward, but following the steps carefully will help you get the most from each session. If you're new to electrotherapy, start with shorter sessions and build up gradually.

  1. Ensure the skin at the target area is clean and dry.
  2. Hold the Paingone Plus device firmly against the painful area — the tip should make good contact with the skin.
  3. Press the activation button once to deliver a single electrical pulse.
  4. Repeat the pulse up to 30 times per session, moving the device slightly between pulses if treating a broader area.
  5. Sessions can be repeated several times throughout the day as needed.
  6. After use, store the device safely and check the battery level.
Indication Age Group Pulses per Session Frequency
Joint or muscle pain Adults (18+) Up to 30 pulses Several times daily as needed
Back pain Adults (18+) Up to 30 pulses Several times daily as needed
Arthritis discomfort Adults (18+) Up to 30 pulses Several times daily as needed

If you're also managing pain with topical treatments, you may find our creams and ointments range a useful complement to electrotherapy.

 

What Are the Possible Side Effects of Paingone Plus?

 

Because Paingone Plus is a physical device rather than a medicine, it has a very limited side effect profile. Most people tolerate it well. That said, some individuals may notice mild reactions, particularly when first using the device.

Common side effects:

  • Mild tingling or buzzing sensation at the application site
  • Temporary skin redness where the device tip contacts the skin
  • A brief warm sensation during or after use

Less common side effects:

  • Minor skin irritation or sensitivity with repeated use on the same area
  • Muscle twitching if the device is held in one position for an extended period

If you experience any persistent skin reaction, unusual discomfort, or worsening pain after use, stop using the device and consult your pharmacist or GP. Serious adverse reactions are not expected with correct use of a TENS device, but any unexpected response warrants professional assessment.

 

How Should You Store Paingone Plus?

 

Proper storage helps maintain the device's performance and extends its lifespan. Follow these guidelines:

  • Store in a cool, dry place — avoid bathrooms or areas with high humidity
  • Keep away from direct sunlight and extreme temperatures
  • Store out of reach of children
  • Do not immerse in water or expose to liquids
  • Replace the battery when the pulse sensation weakens or becomes inconsistent
  • Clean the device tip with a dry cloth after each use — do not use liquid cleaners

For those managing ongoing pain conditions, it's also worth exploring our broader vitamins and supplements range, which includes products that may support joint and muscle health as part of a wider wellness approach.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Paingone Plus online in the UK?

You can buy Paingone Plus directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for £43.95. It's available without a prescription and comes with fast UK delivery. Simply add it to your basket and check out securely through our website.

How does Paingone Plus work in the body?

Paingone Plus uses transcutaneous electrical nerve stimulation (TENS) to send small electrical pulses through the skin surface. These pulses interfere with pain signals travelling along nerve fibres to the brain — a process explained by the gate control theory of pain. The stimulation may also encourage the release of endorphins, the body's natural pain-modulating chemicals.

How do I use Paingone Plus step by step?

Press the tip of the device firmly against the painful area, ensuring good skin contact. Press the activation button to deliver a pulse, and repeat up to 30 times per session. You can repeat sessions several times throughout the day — there's no complicated setup and no electrode pads needed.

How many times a day can I use Paingone Plus?

Paingone Plus can be used multiple times daily as needed. Each session involves up to 30 pulses applied to the affected area. There is no strict maximum number of daily sessions, but if pain persists or worsens despite regular use, you should consult your GP or pharmacist.

What types of pain can Paingone Plus help with?

Paingone Plus is designed for localised pain including joint pain, lower back pain, muscle aches, arthritis discomfort, shoulder and neck pain, and sports-related soreness. It is intended as a complementary, drug-free option rather than a replacement for medical treatment. If you're unsure whether it's right for your condition, speak to your pharmacist.

Who should not use Paingone Plus?

Paingone Plus is not suitable for people with cardiac pacemakers, implanted defibrillators, or any other active implanted electronic device. It should also be avoided during pregnancy unless a healthcare professional has specifically advised otherwise, and it is not recommended for children under 18. People with epilepsy or active heart conditions should seek medical advice before use.

What are the side effects of Paingone Plus?

Side effects are uncommon and generally mild. You may notice a tingling or buzzing sensation at the application site, temporary skin redness, or minor irritation with repeated use on the same area. These effects are usually short-lived and resolve on their own. If you experience persistent skin reactions or worsening pain, stop use and consult a healthcare professional.

How does Paingone Plus compare to a standard TENS machine?

Paingone Plus is a compact, pen-style device that requires no electrode pads or wires, making it far more portable than a traditional TENS machine. A conventional TENS machine typically covers a broader area and offers adjustable intensity settings, whereas Paingone Plus delivers targeted point stimulation with single-button simplicity. Both are drug-free options available through our electrical health and diagnostic range.

Is Paingone Plus safe to use every day?

Yes, Paingone Plus is generally considered safe for daily use in adults who meet the suitability criteria. Avoid applying it to the same small patch of skin repeatedly without a break, as this may cause localised irritation. If you're using it daily for a persistent condition, it's a good idea to review your pain management plan with your GP.

Can I use Paingone Plus if I am pregnant?

Paingone Plus is not recommended during pregnancy without specific advice from a healthcare professional. TENS devices are sometimes used in labour under medical supervision, but self-directed use during pregnancy — particularly in the first trimester — is not advised. Always consult your midwife or GP before using any electrotherapy device while pregnant.

Does Paingone Plus interact with any medicines?

As a physical device rather than a medicine, Paingone Plus does not interact with oral medications or affect drug metabolism. However, it can interfere with implanted electronic devices such as pacemakers and neurostimulators. If you are taking medicines for a pain condition and want to use Paingone Plus alongside them, speak to your pharmacist for personalised advice.

What are alternatives to Paingone Plus for drug-free pain relief?

Alternatives include traditional wired TENS machines, heat therapy, cold packs, and topical analgesic creams. You can explore a range of options in our pain relief collection, which includes both device-based and topical approaches. The right choice depends on the type, location, and severity of your pain.

How long does it take for Paingone Plus to work?

Some people notice a reduction in pain sensation during or shortly after their first session. For others, particularly those with chronic conditions, it may take several sessions over a few days before a meaningful benefit is felt. TENS therapy generally works best as part of a consistent routine rather than as a one-off treatment.

How long can you use Paingone Plus for?

There is no defined maximum duration for using Paingone Plus, and many people incorporate it into their long-term pain management routine. If you find that pain is not improving after several weeks of regular use, or if it worsens, you should seek a medical review. It is not a substitute for diagnosing or treating the underlying cause of pain.

What does the latest research say about TENS for pain relief?

The NHS acknowledges TENS as a method that some people find helpful for managing pain, particularly musculoskeletal and chronic pain conditions. Research evidence is mixed — some studies show meaningful short-term pain reduction, while others highlight the need for more robust clinical trials. NICE guidelines on chronic pain note that TENS may be considered as part of a broader self-management approach.

How Should You Use Paingone Plus?

Using Paingone Plus correctly is key to getting the most from each session. Before you begin, make sure the skin at the target area is clean, dry, and free from broken or irritated patches.

Do not apply the device over the eyes, throat, front of the neck, or any area of broken or infected skin. Always ensure the tip is clean before each use.

What Is the Correct Dose of Paingone Plus?

Paingone Plus does not involve a pharmacological dose in the traditional sense — instead, the "dose" refers to the number of pulses delivered per session and how frequently sessions are repeated. The table below summarises the recommended usage by indication.

When Is the Best Time to Use Paingone Plus?

There is no single "best" time — Paingone Plus can be used whenever pain flares up, making it a flexible option for both planned and reactive pain management. Many people find it helpful first thing in the morning when joints and muscles feel stiff, or in the evening after a physically demanding day.

If you use it before physical activity, it may help reduce pre-existing discomfort. Using it after exercise may help ease post-activity soreness. The key is consistency — regular use tends to produce better results than occasional, sporadic sessions.

How Long Can You Use Paingone Plus For?

Paingone Plus can be used as part of a long-term pain management routine with no defined maximum duration. Many people with chronic conditions such as arthritis or recurring back pain incorporate it into their daily self-care without issue.

However, if your pain is not improving after several weeks of consistent use, or if it worsens at any point, you should seek a medical review. Paingone Plus is a supportive tool — it does not diagnose or treat the underlying cause of pain, and persistent or unexplained pain always warrants professional assessment.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

How Should You Use Paingone Plus?

Using Paingone Plus correctly is key to getting the most from each session. Before you begin, make sure the skin at the target area is clean, dry, and free from broken or irritated patches.

Do not apply the device over the eyes, throat, front of the neck, or any area of broken or infected skin. Always ensure the tip is clean before each use.

What Is the Correct Dose of Paingone Plus?

Paingone Plus does not involve a pharmacological dose in the traditional sense — instead, the "dose" refers to the number of pulses delivered per session and how frequently sessions are repeated. The table below summarises the recommended usage by indication.

When Is the Best Time to Use Paingone Plus?

There is no single "best" time — Paingone Plus can be used whenever pain flares up, making it a flexible option for both planned and reactive pain management. Many people find it helpful first thing in the morning when joints and muscles feel stiff, or in the evening after a physically demanding day.

If you use it before physical activity, it may help reduce pre-existing discomfort. Using it after exercise may help ease post-activity soreness. The key is consistency — regular use tends to produce better results than occasional, sporadic sessions.

How Long Can You Use Paingone Plus For?

Paingone Plus can be used as part of a long-term pain management routine with no defined maximum duration. Many people with chronic conditions such as arthritis or recurring back pain incorporate it into their daily self-care without issue.

However, if your pain is not improving after several weeks of consistent use, or if it worsens at any point, you should seek a medical review. Paingone Plus is a supportive tool — it does not diagnose or treat the underlying cause of pain, and persistent or unexplained pain always warrants professional assessment.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Paingone Plus?

Because Paingone Plus is a physical electrotherapy device rather than a medicine, its side effect profile is minimal compared to oral pain relief options. Most people tolerate it without any issues. That said, some mild reactions can occur, particularly when you first start using the device or if you apply it to a sensitive area.

  • Mild tingling or buzzing sensation at the point of contact
  • Temporary skin redness directly under the device tip
  • A brief warm sensation during or immediately after use

What Are the Less Common Side Effects of Paingone Plus?

Less commonly, some users may notice reactions with repeated or prolonged use on the same area of skin. These are generally mild and resolve quickly once you stop using the device on that spot.

  • Minor skin irritation or sensitivity with repeated application to the same site
  • Localised muscle twitching if the device is held stationary for an extended period
  • Temporary discomfort if the device is used on an area with heightened nerve sensitivity

What Are the Serious Side Effects of Paingone Plus?

Serious adverse reactions from a correctly used TENS device are not expected. However, using Paingone Plus in contraindicated circumstances — such as near an implanted pacemaker or over broken skin — could pose a genuine risk. If you experience chest pain, palpitations, dizziness, or any unusual systemic symptom during or after use, stop immediately and seek urgent medical attention. These reactions would be unexpected and may indicate an underlying condition rather than a direct device effect.

What Should You Do If You Experience Side Effects?

For mild reactions such as skin redness or tingling, simply stop using the device on that area and allow the skin to recover before resuming. Avoid applying the device to the same small patch of skin in every session — moving the tip slightly between pulses helps distribute the stimulation and reduces localised irritation. If a skin reaction persists for more than 24 hours, consult your pharmacist. For any unexpected or concerning symptom, stop use and seek professional advice promptly.

Can Paingone Plus Interact With Other Medicines or Devices?

As a non-pharmacological device, Paingone Plus does not interact with oral medicines or affect how your body processes drugs. However, it can interfere with implanted electronic devices. People with cardiac pacemakers, implanted cardioverter defibrillators (ICDs), or spinal cord stimulators must not use Paingone Plus, as the electrical pulses could disrupt device function. If you are unsure whether any implanted device you have is affected, consult your cardiologist or specialist before use.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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