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Otrivine Adult Nasal Drops 10ml

Otrivine Adult Nasal Drops 10ml

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  • ✔️ Relieves nasal congestion fast — works within minutes
  • ✔️ Contains xylometazoline 0.1% for targeted decongestant action
  • ✔️ Suitable for adults and adolescents aged 12 and over
  • ✔️ Effective for colds, sinusitis, hay fever, and rhinitis
  • ✔️ Compact 10ml bottle — easy to use at home or on the go

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What Are Otrivine Adult Nasal Drops Used For?

 

If you have ever struggled to breathe through a stuffy, blocked nose — whether from a cold, sinusitis, or hay fever — you will know how miserable it can be. Otrivine adult nasal drops offer fast-acting, targeted relief from nasal congestion, helping to clear your airways so you can breathe more comfortably again. Each 10ml bottle contains xylometazoline hydrochloride 0.1%, a well-established nasal decongestant used widely across the UK. You can browse our full range of ear, nose, and throat treatments if you are looking for additional support alongside this product.

Nasal congestion happens when the blood vessels inside your nasal passages become swollen and inflamed, often in response to infection, allergens, or irritants. The NHS recognises nasal congestion as one of the most common symptoms associated with colds and upper respiratory tract infections. Otrivine works directly at the site of congestion, making it a practical choice for adults and young people aged 12 and over who need quick relief.

 

How Do Otrivine Adult Nasal Drops Work?

 

The active ingredient, xylometazoline hydrochloride, belongs to a class of medicines called sympathomimetic decongestants. It works by stimulating alpha-adrenergic receptors in the nasal mucosa, causing the blood vessels to constrict. This reduces swelling of the nasal lining and decreases mucus secretion, opening up the nasal passages within minutes.

  • Xylometazoline binds to alpha-adrenergic receptors in nasal blood vessels
  • Blood vessels constrict, reducing swelling of the nasal mucosa
  • Mucus production decreases, easing congestion
  • Relief typically begins within a few minutes and can last several hours

 

Who Should Use Otrivine Adult Nasal Drops?

 

These drops are intended for adults and adolescents aged 12 years and over. They are suitable for short-term relief of nasal congestion caused by a range of conditions. If your blocked nose is linked to seasonal allergies, you might also find it helpful to explore our allergy and hay fever treatments for a more complete approach to symptom management.

  • Adults and adolescents aged 12 and over with nasal congestion
  • People with cold or flu-related blocked nose
  • Those experiencing congestion due to sinusitis or rhinitis
  • Individuals with hay fever-related nasal stuffiness

 

How Do Otrivine Nasal Drops Compare to a Nasal Spray?

 

Feature Otrivine Adult Nasal Drops Otrivine Adult Nasal Spray
Active ingredient Xylometazoline HCl 0.1% Xylometazoline HCl 0.1%
Application method Drops instilled into nostril Metered pump spray
Dose control 2–3 drops per nostril 1 spray per nostril
Suitable age 12 years and over 12 years and over

 

How Should You Store Otrivine Adult Nasal Drops?

 

Store your Otrivine adult nasal drops below 25°C, away from direct sunlight and out of the reach of children. Once opened, the bottle should be used by one person only to avoid cross-contamination. Do not use the drops after the expiry date printed on the packaging.

It is worth noting that the dropper tip should not come into contact with the inside of your nose during use. This helps to keep the solution sterile and reduces the risk of introducing bacteria into the bottle. If you notice any change in colour or clarity of the solution, do not use it.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Otrivine Adult Nasal Drops 10ml specifications
Treatment category Nasal decongestant
Mechanism of action Alpha-adrenergic agonist — constricts nasal blood vessels
Effective for Nasal congestion due to colds, sinusitis, rhinitis, hay fever
Suitable for Adults and adolescents aged 12 and over
Active ingredient Xylometazoline hydrochloride 0.1%
Pack size 10ml
Strength 0.1% w/v
UK classification General Sale List (GSL)
Drug class Sympathomimetic decongestant
Preparation Nasal drops solution
Route of administration Intranasal

Specifications of Otrivine Adult Nasal Drops 10ml

 

What Is Otrivine Adult Nasal Drops and What Is It Used For?

 

Otrivine Adult Nasal Drops 10ml is an over-the-counter nasal decongestant containing xylometazoline hydrochloride 0.1%. It is used to relieve the symptoms of nasal congestion — that uncomfortable blocked, stuffy feeling in your nose — caused by conditions such as the common cold, acute or chronic sinusitis, allergic rhinitis, and hay fever. The NHS describes nasal congestion as one of the most frequently reported symptoms of upper respiratory infections, and it can significantly affect sleep, concentration, and daily comfort.

This medicine is for short-term use only. It is not a treatment for the underlying cause of your congestion — it simply reduces the swelling in your nasal passages to make breathing easier while your body recovers or while other treatments take effect.

 

What Do You Need to Know Before Using Otrivine Adult Nasal Drops?

 

Before using these drops, it is important to check whether they are suitable for you. Do not use Otrivine Adult Nasal Drops if any of the following apply:

  • You are under 12 years of age
  • You have had a transnasal hypophysectomy (surgical removal of the pituitary gland through the nose) or similar surgery exposing the dura mater
  • You are allergic to xylometazoline hydrochloride or any other ingredient in the product
  • You have dry nasal mucosa (atrophic rhinitis)
  • You are taking or have taken monoamine oxidase inhibitors (MAOIs) within the last 14 days
  • You have angle-closure glaucoma

Speak to your doctor or pharmacist before use if you have any of the following conditions:

  • High blood pressure (hypertension)
  • Heart disease or irregular heartbeat
  • An overactive thyroid (hyperthyroidism)
  • Diabetes mellitus
  • Enlarged prostate (benign prostatic hyperplasia)
  • Phaeochromocytoma

Known drug interactions to be aware of include:

  • MAOIs — risk of hypertensive crisis; do not use together
  • Tricyclic antidepressants — may enhance the cardiovascular effects of xylometazoline
  • Other sympathomimetic medicines — additive effects possible

If you are pregnant or breastfeeding, seek medical advice before using this product. Xylometazoline is generally not recommended during pregnancy without a doctor's guidance.

 

How Should You Use Otrivine Adult Nasal Drops?

 

Always use this medicine exactly as described in the patient information leaflet or as directed by your pharmacist. Do not exceed the stated dose.

  1. Blow your nose gently before use to clear any mucus
  2. Tilt your head back slightly
  3. Hold the dropper bottle upright and place the tip just at the entrance of one nostril — do not insert it deeply
  4. Instil 2 to 3 drops into the nostril
  5. Repeat for the other nostril
  6. Breathe in gently through your nose after applying the drops
  7. Replace the cap securely after use
Indication Age Group Dose Frequency
Nasal congestion Adults and adolescents (12+) 2–3 drops per nostril Up to 3 times daily
Nasal congestion Children under 12 Not suitable Not applicable

Do not use for more than 7 consecutive days without medical advice. If your symptoms persist beyond this period, consult your GP. You may also find it useful to explore our cold and flu treatments if congestion is part of a wider set of symptoms.

 

What Are the Possible Side Effects of Otrivine Adult Nasal Drops?

 

Like all medicines, Otrivine Adult Nasal Drops can cause side effects, although not everyone experiences them. Most side effects are mild and localised to the nasal area.

Common side effects:

  • Temporary burning or stinging sensation in the nose
  • Nasal dryness or irritation
  • Increased nasal secretions shortly after use
  • Sneezing

Less common side effects:

  • Headache
  • Nausea
  • Palpitations or increased heart rate
  • Rebound congestion (rhinitis medicamentosa) with prolonged use beyond 7 days
  • Insomnia or restlessness

If you experience any serious side effects such as chest pain, severe headache, or a significant rise in blood pressure, stop using the drops and seek medical attention promptly. For additional support with related symptoms, our allergy and hay fever section has a range of complementary options.

 

How Should You Store Otrivine Adult Nasal Drops?

 

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the label or carton
  • Do not share the bottle with other people — this is a single-person product
  • Do not freeze
  • Dispose of any unused medicine safely — ask your pharmacist how to dispose of medicines you no longer need

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Otrivine Adult Nasal Drops online in the UK?

You can buy Otrivine Adult Nasal Drops 10ml online from Cured Pharmacy for just £4.85, with no prescription required. It is a General Sale List (GSL) medicine, meaning it is available over the counter from registered UK pharmacies. Simply add it to your basket and it will be dispatched directly to your door.

How do Otrivine Adult Nasal Drops work in the body?

Otrivine Adult Nasal Drops contain xylometazoline hydrochloride 0.1%, which acts as an alpha-adrenergic agonist. It stimulates receptors in the blood vessels lining the nasal passages, causing them to constrict and reducing the swelling that causes congestion. Relief typically begins within a few minutes of application and can last for several hours.

How do I use Otrivine Adult Nasal Drops step by step?

Blow your nose gently first, then tilt your head back and place the dropper tip at the entrance of one nostril without inserting it deeply. Instil 2 to 3 drops, breathe in gently, then repeat for the other nostril. You can use the drops up to three times a day, but never exceed this frequency or use for more than 7 consecutive days.

How quickly do Otrivine nasal drops start to work?

Most people notice relief from nasal congestion within a few minutes of using Otrivine Adult Nasal Drops. The decongestant effect of xylometazoline is rapid because it acts directly on the blood vessels in the nasal lining. The duration of relief can last for several hours, making it useful before sleep or during the day when congestion is most disruptive.

What is the correct dose of Otrivine Adult Nasal Drops?

The recommended dose for adults and adolescents aged 12 and over is 2 to 3 drops into each nostril, up to three times daily. Do not use more than the stated dose, and do not use for longer than 7 consecutive days without speaking to a doctor. These drops are not suitable for children under 12 years of age.

What are the side effects of Otrivine Adult Nasal Drops?

Common side effects include a temporary burning or stinging sensation in the nose, nasal dryness, and sneezing. Less commonly, you may experience headache, nausea, or palpitations. Using the drops for more than 7 days can cause rebound congestion — where the nose becomes more blocked when the drops wear off — so always stick to the recommended duration.

Can I use Otrivine nasal drops if I am pregnant or breastfeeding?

Otrivine Adult Nasal Drops are not generally recommended during pregnancy or breastfeeding without medical advice, as xylometazoline may have effects on blood flow. You should speak to your GP or pharmacist before using this product if you are pregnant, planning to become pregnant, or currently breastfeeding. They can advise on safer alternatives if needed.

Who should not use Otrivine Adult Nasal Drops?

These drops are not suitable for children under 12, people with atrophic rhinitis (dry nasal mucosa), or those who have had certain nasal surgeries exposing the dura mater. You should also avoid them if you are taking MAOIs or have angle-closure glaucoma. People with high blood pressure, heart disease, diabetes, or an overactive thyroid should consult a doctor before use.

What happens if I use Otrivine nasal drops for more than 7 days?

Using Otrivine Adult Nasal Drops for more than 7 consecutive days can lead to a condition called rhinitis medicamentosa, or rebound congestion. This happens because the nasal blood vessels become dependent on the decongestant and swell more when it wears off, making congestion worse than before. If this occurs, stop using the drops and speak to your pharmacist or GP.

Can Otrivine nasal drops interact with other medicines?

Yes — Otrivine Adult Nasal Drops can interact with monoamine oxidase inhibitors (MAOIs), which can cause a dangerous rise in blood pressure, so do not use them together or within 14 days of stopping an MAOI. Tricyclic antidepressants and other sympathomimetic medicines may also interact. Always tell your pharmacist about all medicines you are taking before starting this product.

Are Otrivine nasal drops suitable for hay fever congestion?

Yes, Otrivine Adult Nasal Drops can help relieve nasal congestion caused by hay fever and allergic rhinitis. However, they do not treat the underlying allergic response, so you may benefit from using them alongside antihistamines or nasal corticosteroid sprays. You can explore a wider range of options in our allergy and hay fever collection.

What are the alternatives to Otrivine Adult Nasal Drops?

Alternatives include other xylometazoline-based nasal sprays, oxymetazoline products such as Sudafed Blocked Nose Spray, or saline nasal rinses for milder congestion. For allergy-related congestion, nasal corticosteroid sprays such as Beconase or Flixonase may be more appropriate for longer-term use. Your pharmacist can help you decide which option suits your situation best.

Can I use Otrivine nasal drops alongside cold and flu remedies?

You should be cautious about combining Otrivine Adult Nasal Drops with other decongestant-containing cold and flu remedies, as this can increase the risk of side effects such as raised blood pressure or palpitations. Always check the ingredients of any other cold remedy you are taking and ask your pharmacist for advice. You can also browse our cold and flu treatments for suitable options.

How should I store Otrivine Adult Nasal Drops?

Store Otrivine Adult Nasal Drops below 25°C, away from direct sunlight and heat, and keep them out of the reach of children. Do not freeze the solution, and do not use the drops after the expiry date printed on the packaging. The bottle should only be used by one person to prevent cross-contamination.

What is the latest guidance on using nasal decongestant drops?

Current NHS and clinical guidance consistently recommends limiting the use of topical nasal decongestants such as xylometazoline to no more than 7 consecutive days to avoid rebound congestion. For persistent nasal symptoms lasting beyond this period, a GP assessment is recommended to rule out underlying conditions such as chronic sinusitis or nasal polyps. Saline irrigation is increasingly recommended as a safe, non-medicated adjunct for ongoing nasal congestion.

How Should You Use Otrivine Adult Nasal Drops?

Using Otrivine Adult Nasal Drops correctly makes a real difference to how well they work. Before you start, blow your nose gently to clear any mucus — this helps the drops reach the nasal lining more effectively.

The dropper tip should not touch the inside of your nose during application. This keeps the solution clean and reduces the risk of contamination between uses.

What Is the Correct Dose of Otrivine Adult Nasal Drops?

Always follow the dosage instructions on the packaging or as directed by your pharmacist. Do not use more drops than recommended, as this will not improve relief and may increase the risk of side effects.

There should be at least 6 to 8 hours between each application. Never exceed three applications in a 24-hour period.

When Is the Best Time to Use Otrivine Adult Nasal Drops?

There is no single fixed time of day that is medically required, but many people find it most helpful to use the drops before bed to ease nighttime breathing and improve sleep quality. Using a dose in the morning can also help you start the day more comfortably if congestion is severe.

If you are using the drops to help with sinusitis or to allow other nasal sprays (such as corticosteroid sprays) to penetrate more effectively, applying Otrivine a few minutes beforehand can help clear the passage first. Always leave adequate time between doses.

How Long Can You Use Otrivine Adult Nasal Drops For?

Otrivine Adult Nasal Drops are intended for short-term use only. You should not use them for more than 7 consecutive days. Using them beyond this period significantly increases the risk of rebound congestion — a condition where the nasal passages become more congested than before once the drops wear off.

If your symptoms have not improved after 7 days, or if they worsen at any point, stop using the drops and consult your GP. Persistent nasal congestion may indicate an underlying condition such as chronic sinusitis or nasal polyps that requires a different approach to treatment.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Otrivine Adult Nasal Drops?

Most people tolerate Otrivine Adult Nasal Drops well when used as directed. However, because the drops act directly on the nasal lining, some localised effects are possible, particularly when you first start using them.

  • Temporary burning or stinging sensation inside the nose
  • Nasal dryness or irritation
  • Increased nasal secretions shortly after application
  • Sneezing immediately after use

These effects are usually mild and short-lived. They tend to settle as your nose adjusts to the drops and do not typically require you to stop treatment.

What Are the Less Common Side Effects of Otrivine Adult Nasal Drops?

Some people may experience side effects that go beyond the nasal area, particularly if the drops are absorbed into the bloodstream. These are less common but worth being aware of.

  • Headache
  • Nausea
  • Palpitations or a faster-than-normal heartbeat
  • Insomnia or difficulty sleeping
  • Restlessness or agitation
  • Rebound congestion (rhinitis medicamentosa) — particularly with use beyond 7 days

Rebound congestion is one of the most clinically significant concerns with prolonged use of topical nasal decongestants. If you notice your nose becoming more blocked between doses rather than less, this may be a sign that rebound congestion is developing.

What Are the Serious Side Effects of Otrivine Adult Nasal Drops?

Serious side effects are rare when Otrivine Adult Nasal Drops are used correctly and for the recommended duration. However, you should stop using the drops and seek urgent medical attention if you experience any of the following:

  • Chest pain or tightness
  • A significant or sudden rise in blood pressure
  • Severe or persistent headache
  • Irregular or very rapid heartbeat
  • Difficulty breathing unrelated to nasal congestion

These symptoms may indicate a systemic reaction to xylometazoline, particularly in people with pre-existing cardiovascular conditions. If you have high blood pressure or heart disease, speak to your doctor before using this product.

What Should You Do If You Experience Side Effects?

If you experience mild side effects such as nasal dryness or stinging, these will usually resolve on their own and do not require you to stop treatment. Reducing the number of drops used or spacing out applications may help. For more troublesome or persistent side effects, stop using the drops and speak to your pharmacist or GP.

If you suspect you are experiencing a serious reaction — particularly cardiovascular symptoms — stop use immediately and seek medical help. You can also report suspected side effects to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Otrivine Adult Nasal Drops Interact With Other Medicines?

Yes. Xylometazoline can interact with certain medicines, and some combinations can be dangerous. The most significant interaction is with monoamine oxidase inhibitors (MAOIs) — using these together can cause a severe and potentially life-threatening rise in blood pressure. Do not use Otrivine if you are taking an MAOI or have taken one within the past 14 days.

Tricyclic antidepressants may also enhance the cardiovascular effects of xylometazoline. Other sympathomimetic medicines — including some cold and flu remedies containing pseudoephedrine or phenylephrine — can have additive effects. Always tell your pharmacist about every medicine you are taking, including over-the-counter products and supplements, before starting Otrivine Adult Nasal Drops.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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