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Neutrogena Concentrated Hand Cream 50ml

Neutrogena Concentrated Hand Cream 50ml

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  • ✔️ Glycerin formula draws moisture deep into dry, rough skin
  • ✔️ Concentrated — one pea-sized amount treats both hands
  • ✔️ Relieves chapping and tightness caused by frequent handwashing
  • ✔️ Non-greasy texture absorbs quickly without leaving residue
  • ✔️ Suitable for daily use by adults with very dry or cracked hands

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What Is Neutrogena Concentrated Hand Cream?

 

If your hands feel rough, tight, or uncomfortably dry — especially after frequent washing or cold weather — you are not alone. Dry skin on the hands is one of the most common skin complaints in the UK, and finding a product that actually works can feel like a challenge. Neutrogena concentrated hand cream is a well-established, dermatologist-recommended moisturiser designed specifically for very dry and chapped hands. Available in a compact 50ml tube, it delivers targeted hydration without feeling greasy or heavy. You can browse a wider range of topical skin treatments in our creams and ointments collection.

The NHS recognises that emollients — moisturising treatments that soften and soothe the skin — are a cornerstone of managing dry skin conditions. Neutrogena's hand cream falls into this category, offering a straightforward, accessible option for everyday use at just £2.99.

 

How Does Neutrogena Concentrated Hand Cream Work?

 

The cream's key active ingredient is glycerin (also known as glycerol), a well-studied humectant. Humectants work by attracting water molecules from the deeper layers of the skin and from the surrounding environment, drawing them into the stratum corneum — the outermost layer of the skin. This process helps to restore the skin's natural moisture balance and supports the skin barrier function.

  • Glycerin draws moisture into the outer skin layers, reducing dryness and tightness
  • Emollient components soften rough, flaky skin texture
  • The concentrated formula means a small amount goes a long way
  • Regular use helps maintain the skin's protective barrier against environmental triggers

 

Who Should Use Neutrogena Concentrated Hand Cream?

 

This cream is suitable for most adults who experience dry, rough, or chapped hands. It is particularly useful for people whose hands are exposed to frequent washing, harsh detergents, or cold and windy weather. Healthcare workers, those in manual trades, and anyone who finds their hands drying out during winter months may find it especially helpful.

  • Adults with dry or very dry hands
  • People who wash their hands frequently (e.g. healthcare or food industry workers)
  • Those experiencing seasonal dryness or chapping
  • Individuals looking for a simple, affordable daily hand moisturiser

 

How Does Neutrogena Concentrated Hand Cream Compare to Other Hand Creams?

 

Feature Neutrogena Concentrated Hand Cream 50ml Standard High-Street Hand Lotion
Key ingredient Glycerin (humectant) Varies (often water-based)
Concentration Concentrated — small amount needed Standard — larger amounts required
Texture Non-greasy, absorbs quickly Often lighter but less intensive
Price £2.99 for 50ml Varies widely

 

Is Neutrogena Concentrated Hand Cream Suitable for Sensitive Skin?

 

Generally speaking, yes. The formula is designed to be gentle and is widely used by people with sensitive skin. However, as with any topical product, it is worth checking the full ingredient list if you have known allergies or a history of contact dermatitis. If you are unsure, apply a small amount to the inner wrist first and wait 24 hours before using it more widely. You may also find it helpful to explore our broader skin care collection for additional options suited to sensitive or reactive skin types.

Store the cream below 25°C, away from direct sunlight, and keep it out of reach of children. Do not use on broken or infected skin without seeking advice from a healthcare professional first.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Neutrogena Concentrated Hand Cream 50ml specifications
Treatment category Dry skin / Emollient
Mechanism of action Humectant — draws and retains moisture in the skin
Effective for Dry, rough, and chapped hands
Suitable for Adults; check ingredients if sensitive skin
Active ingredient Glycerin
Pack size 50ml
UK classification General Sale / Cosmetic
Preparation Cream
Route of administration Topical (skin)

Specifications of Neutrogena Concentrated Hand Cream 50ml

 

What Is Neutrogena Concentrated Hand Cream and What Is It Used For?

 

Neutrogena concentrated hand cream is a topical emollient moisturiser used to relieve and prevent dry, rough, chapped, and cracked hands. It is formulated with glycerin as its primary active ingredient, which works as a humectant to attract and lock moisture into the skin. The cream is available over the counter without a prescription and is suitable for regular, everyday use by most adults.

Dry hands can result from a wide range of causes — frequent handwashing, cold weather, low humidity, occupational exposure to water or chemicals, or underlying skin conditions such as eczema or psoriasis. The NHS advises that emollients should be applied regularly and generously to manage dry skin effectively, and this cream fits neatly into that approach.

 

What Do You Need to Know Before Using Neutrogena Concentrated Hand Cream?

 

Before using this cream, read the following carefully. Although it is generally well tolerated, there are some situations where caution is advised.

Do not use this product if:

  • You are allergic to glycerin or any other listed ingredient in the formulation
  • Your skin is broken, infected, or showing signs of a bacterial or fungal skin infection — seek medical advice first
  • You have a known history of severe contact dermatitis to emollient products

Use with caution if:

  • You have very sensitive skin or a history of allergic reactions to topical products
  • You are using other topical treatments on the same area — allow each product to absorb fully before applying another
  • You are pregnant or breastfeeding — while topical glycerin is generally considered safe, it is always sensible to check with your pharmacist

Known drug interactions:

  • No clinically significant drug interactions are known for topically applied glycerin-based hand creams
  • If you are using prescription topical treatments (e.g. corticosteroid creams), apply them separately and allow absorption time between products

 

How Should You Use Neutrogena Concentrated Hand Cream?

 

Using this cream correctly will help you get the most out of it. Because it is a concentrated formula, you genuinely do not need much per application — a pea-sized amount is usually sufficient for both hands.

  1. Wash and dry your hands thoroughly before applying
  2. Squeeze a small, pea-sized amount of cream onto your fingertip
  3. Rub the cream between both palms to warm it slightly
  4. Massage gently into the backs of your hands, fingers, and knuckles
  5. Allow the cream to absorb fully before touching fabrics or surfaces
  6. Reapply as often as needed throughout the day, particularly after handwashing
Indication Age Group Dose Frequency
Dry / rough hands Adults Pea-sized amount As needed, multiple times daily
Chapped or cracked hands Adults Pea-sized amount After each handwash and before bed
Preventative use Adults Small amount Once or twice daily

 

What Are the Possible Side Effects of Neutrogena Concentrated Hand Cream?

 

Side effects from this cream are uncommon, but as with any topical product, some people may experience a reaction. If you notice any of the following, stop using the cream and speak to your pharmacist.

Common side effects:

  • Mild, temporary stinging or tingling on application — particularly if skin is very dry or cracked
  • Slight greasiness immediately after application

Less common side effects:

  • Redness or irritation at the application site
  • Contact dermatitis — an allergic skin reaction causing itching, rash, or swelling
  • Skin sensitivity in individuals with known ingredient allergies

Serious allergic reactions (anaphylaxis) to topical hand creams are extremely rare. However, if you experience swelling of the face, lips, or throat, or have difficulty breathing after use, seek emergency medical attention immediately. If you are managing a broader skin condition alongside dry hands, our skin care collection includes a range of products that may complement your routine. For those dealing with itching alongside dryness, you might also find relevant options in our creams and ointments range.

 

How Should You Store Neutrogena Concentrated Hand Cream?

 

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and sources of heat
  • Keep the cap tightly closed when not in use
  • Keep out of reach and sight of children
  • Do not use after the expiry date printed on the tube
  • Do not freeze

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Neutrogena Concentrated Hand Cream online in the UK?

You can buy Neutrogena Concentrated Hand Cream 50ml directly from Cured Pharmacy online for just £2.99, with fast UK delivery. It is available without a prescription as an over-the-counter product. No consultation is required — simply add it to your basket and check out.

How does Neutrogena Concentrated Hand Cream work in the skin?

The cream works primarily through glycerin, a humectant that draws water molecules into the outermost layer of the skin — the stratum corneum — and helps retain them there. This restores the skin's natural moisture balance and softens rough, dry texture. Regular use also helps support the skin's protective barrier function against environmental triggers like cold air and frequent washing.

How do I use Neutrogena Concentrated Hand Cream step by step?

Using the cream correctly is straightforward. Follow these steps:

  1. Wash and dry your hands thoroughly
  2. Squeeze a pea-sized amount onto your fingertip
  3. Massage gently into both hands, including fingers and knuckles
  4. Allow to absorb fully before touching surfaces

Because it is a concentrated formula, you really do not need much — a little goes a long way.

How often should I apply Neutrogena Concentrated Hand Cream each day?

You can apply it as often as needed throughout the day — there is no strict upper limit for a topical emollient used on intact skin. Most people find applying it after every handwash and once more before bed gives the best results. Consistent use is key to keeping hands soft and comfortable, particularly during colder months.

What are the side effects of Neutrogena Concentrated Hand Cream?

Side effects are uncommon but can include:

  • Mild stinging or tingling on application, especially on very dry or cracked skin
  • Temporary redness or irritation at the application site
  • Rarely, contact dermatitis in individuals with ingredient sensitivities

If you notice persistent irritation or a rash, stop using the cream and speak to your pharmacist.

Is Neutrogena Concentrated Hand Cream suitable for people with eczema?

Emollients like this cream are commonly recommended as part of eczema management, and the NHS advises regular emollient use to keep skin hydrated and reduce flare-ups. However, if you have diagnosed eczema, it is worth checking with your GP or dermatologist before introducing a new product, as individual skin sensitivities vary. You may also find additional suitable options in our skin care collection.

Can I use Neutrogena Concentrated Hand Cream on broken or cracked skin?

You should avoid applying any topical cream to broken, infected, or severely cracked skin without first seeking advice from a pharmacist or GP. Minor surface dryness and superficial cracking are generally fine to treat with an emollient, but deeper cracks or signs of infection need professional assessment. If in doubt, ask your pharmacist before use.

Who is eligible to use Neutrogena Concentrated Hand Cream?

The cream is suitable for most adults experiencing dry, rough, or chapped hands. It is particularly well suited to people who wash their hands frequently, work in cold or outdoor environments, or experience seasonal skin dryness. Those with known allergies to any of the listed ingredients should check the label carefully before use.

What are the alternatives to Neutrogena Concentrated Hand Cream?

There are several alternatives available for dry hand care, including:

  • Other glycerin-based hand creams from pharmacy brands
  • Urea-based creams, which are particularly effective for very thick or rough skin
  • Aqueous cream or emollient ointments for more intensive treatment

Browse our creams and ointments collection for a range of alternatives suited to different skin types and needs.

How long can I use Neutrogena Concentrated Hand Cream for?

Neutrogena concentrated hand cream can be used long term as part of a daily hand care routine — there is no recommended maximum duration for a topical emollient on intact skin. If your symptoms do not improve after several weeks of regular use, or if your skin condition worsens, speak to your pharmacist or GP. Persistent or worsening dryness may indicate an underlying skin condition that needs further assessment.

Can I use Neutrogena Concentrated Hand Cream during pregnancy?

Topically applied glycerin is generally considered safe during pregnancy, as systemic absorption through intact skin is minimal. However, it is always sensible to check with your midwife or pharmacist before introducing any new product during pregnancy. If you have any concerns, your healthcare team can advise on the most appropriate options for you.

Does Neutrogena Concentrated Hand Cream interact with other medicines?

No clinically significant drug interactions are known for topically applied glycerin-based hand creams. If you are using prescription topical treatments on your hands — such as corticosteroid creams — apply them separately and allow each product to absorb fully before applying the next. If you are unsure, ask your pharmacist for guidance.

What is the best time of day to apply Neutrogena Concentrated Hand Cream?

There is no single "best" time — the cream can be applied whenever your hands feel dry or after handwashing. That said, applying it before bed is particularly effective, as the skin has time to absorb the moisture overnight without being washed off. Many people also keep a tube at their desk or in their bag for use throughout the day.

What does the research say about glycerin hand creams for dry skin?

Glycerin is one of the most well-studied humectants in dermatology and is widely recognised for its ability to improve skin hydration and barrier function. The NHS and BNF both acknowledge glycerin-containing emollients as effective treatments for dry skin conditions. It is a well-established ingredient with a long safety record in topical skincare formulations.

How should I store Neutrogena Concentrated Hand Cream?

Store the cream correctly to maintain its quality:

  • Keep below 25°C in a cool, dry place
  • Avoid direct sunlight or heat sources
  • Keep the cap tightly closed when not in use
  • Store out of reach of children
  • Do not use after the expiry date on the tube

How Should You Use Neutrogena Concentrated Hand Cream?

Using this cream correctly makes a real difference to how well it works. Because it is a concentrated formula, you only need a small amount per application — resist the urge to use more than necessary, as a little genuinely goes a long way. Apply to clean, dry hands for best results.

What Is the Correct Dose of Neutrogena Concentrated Hand Cream?

There is no fixed medical dose for a topical emollient hand cream, but using the right amount ensures you get the most from each tube without waste. A pea-sized amount is sufficient for both hands in most cases. Applying more than this does not necessarily improve results and may leave a residue on the skin.

When Is the Best Time to Use Neutrogena Concentrated Hand Cream?

The most effective times to apply the cream are immediately after washing your hands — when the skin is clean and slightly warm — and just before bed. Overnight application is particularly beneficial because the cream has several hours to work without being washed off. Keeping a tube on your bedside table or at your desk can help you build a consistent routine.

If you work in an environment where your hands are exposed to water, chemicals, or cold air throughout the day, reapplying after each exposure will help maintain the skin barrier and prevent further dryness from developing.

How Long Can You Use Neutrogena Concentrated Hand Cream For?

There is no recommended maximum duration for using a topical emollient on intact skin. You can incorporate this cream into your daily hand care routine for as long as you need it — many people use it year-round, with more frequent application during winter months when skin tends to dry out more quickly.

If your hands do not improve after several weeks of consistent use, or if dryness is accompanied by redness, itching, or cracking that is getting worse, speak to your pharmacist or GP. Persistent symptoms may point to an underlying skin condition that warrants further assessment and treatment.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Neutrogena Concentrated Hand Cream?

Most people use this cream without experiencing any side effects at all. It is generally well tolerated, even with frequent daily use. That said, as with any topical product, a small number of people may notice mild reactions, particularly when first starting to use it or if their skin is already very dry or compromised.

  • Mild stinging or tingling on application, especially on very dry or cracked skin
  • Temporary greasiness or residue immediately after applying
  • Slight warmth or flushing at the application site

What Are the Less Common Side Effects of Neutrogena Concentrated Hand Cream?

Less commonly, some individuals may experience a more noticeable skin reaction. This is more likely in people with sensitive skin or a history of reactions to topical products. If any of the following occur, stop using the cream and consult your pharmacist.

  • Persistent redness or irritation at the application site
  • Itching or a burning sensation that does not settle within a few minutes
  • Dry, flaky, or peeling skin that worsens after use
  • Contact dermatitis — an allergic skin reaction causing a rash, swelling, or blistering

What Are the Serious Side Effects of Neutrogena Concentrated Hand Cream?

Serious reactions to topical glycerin-based hand creams are extremely rare. However, you should be aware of the signs of a severe allergic reaction (anaphylaxis), which — while very unlikely — can occur with any product. Seek emergency medical attention immediately if you experience any of the following after use:

  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Sudden widespread rash or hives across the body
  • Dizziness, rapid heartbeat, or feeling faint

What Should You Do If You Experience Side Effects?

If you notice mild irritation or redness, stop applying the cream to the affected area and allow the skin to settle. Rinsing the area with cool water may help. For persistent or worsening reactions, speak to your pharmacist — they can advise whether you should continue, switch to an alternative product, or seek further medical assessment.

Do not ignore a skin reaction that is spreading, blistering, or accompanied by pain. These symptoms may indicate contact dermatitis or another skin condition that needs proper diagnosis and treatment from a GP or dermatologist.

Can Neutrogena Concentrated Hand Cream Interact With Other Medicines?

No clinically significant interactions are known between topically applied glycerin-based hand creams and other medicines. The systemic absorption of glycerin through intact skin is minimal, making interactions with oral or injectable medicines highly unlikely. However, if you are using prescription topical treatments on your hands — such as corticosteroid creams, antifungal preparations, or other medicated products — apply them separately and allow each to absorb fully before applying the next. If you are unsure about using multiple topical products together, your pharmacist can advise on the correct order and timing of application.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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