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Murine Refresh & Soothe Eye Mist 15ml

Murine Refresh & Soothe Eye Mist 15ml

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  • ✔️ Soothes dry, gritty, and tired eyes on contact
  • ✔️ Preservative-free formula suits sensitive eyes
  • ✔️ Spray-on application works over closed eyelids
  • ✔️ Contains sodium hyaluronate to restore eye moisture
  • ✔️ Compact 15ml bottle ideal for on-the-go use

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Is Murine Refresh & Soothe Eye Mist the Right Eye Mist for Dry Eyes?

 

Dry, tired, or irritated eyes are incredibly common — and often made worse by screen time, air conditioning, or environmental allergens. If you've ever struggled with traditional eye drops, you'll know how fiddly they can be. That's where an eye mist for dry eyes like Murine Refresh & Soothe Eye Mist 15ml comes in. Rather than requiring you to tilt your head back and aim a drop directly onto your eyeball, this gentle spray can be applied to closed eyelids, making it far more accessible for people who find conventional drops uncomfortable or difficult to use. You can browse the full range of products in our eye care collection if you'd like to explore other options alongside this one.

Murine is a well-established brand in the UK eye care market. This particular product is designed to refresh and soothe eyes that feel dry, gritty, or fatigued — whether that's from prolonged screen use, wearing contact lenses, or simply being in a dry or dusty environment. At £7.89 for a 15ml bottle, it offers a convenient, preservative-free format that's easy to carry and use throughout the day.

 

How Does Murine Refresh & Soothe Eye Mist Work?

 

The mechanism behind this eye mist is straightforward but effective. It works by delivering a fine mist of lubricating and protective ingredients directly onto the ocular surface — even through closed eyelids. Here's how it works step by step:

  • Sodium hyaluronate — a naturally occurring substance found in the eye, this ingredient attracts and retains water molecules, helping to restore and maintain moisture on the surface of the eye.
  • Ectoin — a naturally derived amino acid derivative that forms a protective hydration shell around cells, helping to stabilise the tear film and shield the ocular surface from environmental stressors such as pollen, dust, and smoke.
  • Together, these two ingredients work to reduce the sensation of dryness, grittiness, and irritation without the need for preservatives, which can themselves cause sensitivity in some people.
  • The fine mist format means the product spreads evenly across the eye surface upon blinking, mimicking the natural spreading action of a blink.

 

Who Should Use Murine Refresh & Soothe Eye Mist?

 

This product is suitable for a wide range of people experiencing mild to moderate dry eye symptoms. It's particularly useful if you find traditional eye drops difficult to administer, or if you want a quick, discreet option you can use at your desk or on the go. It is suitable for adults and children over the age of 12.

  • People who spend long hours in front of screens (digital eye strain)
  • Contact lens wearers experiencing end-of-day dryness (remove lenses before use)
  • Those exposed to air conditioning, central heating, or dry environments
  • People with mild eye irritation related to environmental factors such as dust or pollen

If you suffer from seasonal eye irritation alongside hay fever, it may also be worth looking at our allergy and hay fever range for additional support.

 

How Does Murine Eye Mist Compare to Standard Eye Drops?

 

Feature Murine Refresh & Soothe Eye Mist Standard Eye Drops (e.g. Hypromellose)
Application method Spray onto closed or open eyelid Drop directly onto open eye
Ease of use High — no need to open eye Moderate — requires precise aim
Preservative-free Yes Varies by product
Active ingredients Sodium hyaluronate, Ectoin Hypromellose or carbomer

 

Is Murine Refresh & Soothe Eye Mist Safe to Store and Use Long-Term?

 

This eye mist for dry eyes is preservative-free, which makes it a good choice for people who use lubricating eye products frequently or who have previously experienced sensitivity to preservatives found in some eye drops. Because it contains no preservatives, it's important to discard the bottle 90 days after first opening to reduce the risk of contamination. Store it below 25°C and keep it away from direct sunlight. Do not freeze the product.

It is not suitable for children under 12 years of age. If you wear contact lenses, always remove them before applying the mist and wait at least 15 minutes before reinserting. If your symptoms are severe, persistent, or accompanied by pain, vision changes, or discharge, you should seek advice from a pharmacist or GP rather than relying solely on an over-the-counter product.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Murine Refresh & Soothe Eye Mist 15ml specifications
Treatment category Dry eye relief / Ocular lubricant
Mechanism of action Lubricates and stabilises the tear film via sodium hyaluronate and ectoin
Effective for Dry, tired, gritty, or irritated eyes
Suitable for Adults and children aged 12 and over
Active ingredients Sodium hyaluronate, Ectoin
Pack size 15ml
UK classification General Sale List (GSL)
Drug class Ocular lubricant / Artificial tear
Preparation Aqueous eye mist spray
Route of administration Ocular (topical spray)

Specifications of Murine Refresh & Soothe Eye Mist 15ml

 

What Is Murine Refresh & Soothe Eye Mist and What Is It Used For?

 

Murine Refresh & Soothe Eye Mist 15ml is an over-the-counter ocular lubricant spray used to relieve the symptoms of dry, irritated, or tired eyes. It is classified as a General Sale List (GSL) medicine in the UK, meaning you can purchase it without a prescription. The product is designed to supplement the natural tear film when it is insufficient — a condition the NHS describes as dry eye syndrome, which can cause discomfort, a gritty sensation, and sensitivity to light.

Dry eye is extremely common. The NHS notes that it tends to affect older adults more frequently, though it can occur at any age and is often worsened by environmental factors, prolonged screen use, or contact lens wear. This eye mist for dry eyes provides a convenient, preservative-free way to manage these symptoms throughout the day.

 

What Do You Need to Know Before Using Murine Refresh & Soothe Eye Mist?

 

Before using this product, read the following contraindications and warnings carefully:

  • Do not use if you are allergic to any of the ingredients listed on the packaging.
  • Not suitable for children under 12 years of age.
  • Remove contact lenses before use; wait at least 15 minutes before reinserting.
  • Do not use if you have an eye infection, eye injury, or have recently had eye surgery — seek medical advice first.
  • If you experience eye pain, sudden vision changes, or worsening redness, stop use immediately and consult a GP or optometrist.
  • Discard 90 days after opening to prevent microbial contamination.

Regarding drug interactions, no significant interactions with systemic medicines have been identified for topical ocular lubricants of this type. However:

  • If you use other eye drops or eye medications, apply Murine Eye Mist first and wait at least 5 minutes before using any other ocular preparation.
  • Always inform your pharmacist of all medicines you are taking, including eye preparations.

 

How Should You Use Murine Refresh & Soothe Eye Mist?

 

Using this product correctly ensures you get the most benefit from each application. Follow these steps:

  1. Wash your hands thoroughly before handling the bottle.
  2. If wearing contact lenses, remove them before use.
  3. Hold the bottle approximately 10 cm away from your closed eye.
  4. Spray 1–2 times onto the closed eyelid.
  5. Blink gently to allow the mist to spread evenly across the eye surface.
  6. Repeat for the other eye if needed.
  7. Wait at least 15 minutes before reinserting contact lenses.
Indication Age Group Dose Frequency
Dry / irritated eyes Adults & children 12+ 1–2 sprays per eye As needed throughout the day
Not applicable Under 12 years Not recommended

 

What Are the Possible Side Effects of Murine Refresh & Soothe Eye Mist?

 

Side effects with this product are uncommon, but as with any ocular preparation, some people may experience mild reactions. The NHS advises that if any side effect is severe or persistent, you should seek medical advice promptly.

Common side effects:

  • Brief, mild stinging or burning sensation immediately after application
  • Temporary blurred vision (clears quickly with blinking)

Less common side effects:

  • Mild redness of the eye
  • Watering or increased tear production immediately after use
  • Sensitivity or discomfort if used over contact lenses (avoid this)

If you notice any signs of an allergic reaction — such as swelling around the eye, severe redness, or a rash — stop using the product immediately and seek medical attention. You can find further guidance on managing eye conditions through the NHS website.

 

How Should You Store Murine Refresh & Soothe Eye Mist?

 

Correct storage helps maintain the product's safety and effectiveness. If you're looking for other health products that require careful storage, our eye care collection includes a range of options with clear storage guidance.

  • Store below 25°C in a cool, dry place.
  • Do not freeze.
  • Keep away from direct sunlight and heat sources.
  • Keep the cap tightly closed when not in use.
  • Discard the bottle 90 days after first opening — write the opening date on the bottle.
  • Keep out of the reach and sight of children.
  • Do not use after the expiry date printed on the packaging.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Murine Refresh & Soothe Eye Mist online in the UK?

You can buy Murine Refresh & Soothe Eye Mist 15ml directly from Cured Pharmacy, a UK GPhC-registered online pharmacy, for £7.89. It's available without a prescription and can be ordered quickly and discreetly. Browse our full eye care collection for related products too.

How does Murine Refresh & Soothe Eye Mist work in the eye?

The mist contains sodium hyaluronate, which attracts and retains moisture on the ocular surface, and ectoin, which stabilises the tear film and protects cells from environmental stress. When sprayed onto the closed eyelid, the fine mist penetrates through to the eye surface and spreads evenly upon blinking. This helps relieve the dryness, grittiness, and irritation associated with dry eye syndrome.

How do I use Murine Refresh & Soothe Eye Mist step by step?

Hold the bottle approximately 10 cm from your closed eye and spray 1–2 times onto the eyelid, then blink gently to spread the mist. You can also spray onto an open eye if preferred. Always wash your hands first and remove contact lenses before application.

How often can I use Murine eye mist throughout the day?

You can use the eye mist as often as needed — there is no strict daily limit for this type of lubricating ocular spray. Most people find 2–4 applications per day sufficient for managing dry eye symptoms. If you find yourself needing it very frequently or symptoms are not improving, speak to a pharmacist or GP.

Can I use Murine Refresh & Soothe Eye Mist with contact lenses?

No — you should always remove your contact lenses before applying the eye mist. After application, wait at least 15 minutes before reinserting your lenses. Using the spray directly over contact lenses is not recommended and may affect lens integrity or cause discomfort.

Is Murine Refresh & Soothe Eye Mist suitable for children?

This product is suitable for adults and children aged 12 years and over. It is not recommended for children under 12 years of age. If your child is under 12 and experiencing dry or irritated eyes, consult a GP or paediatric optometrist for appropriate advice.

What are the side effects of Murine Refresh & Soothe Eye Mist?

Side effects are uncommon but may include a brief mild stinging sensation or temporary blurred vision immediately after spraying. These effects typically resolve within seconds of blinking. If you experience persistent irritation, redness, swelling, or any signs of an allergic reaction, stop use and seek medical advice promptly.

Does Murine Refresh & Soothe Eye Mist contain preservatives?

No — this eye mist is preservative-free, which makes it a good choice for people who use lubricating eye products frequently or who have experienced sensitivity to preservatives in other eye drops. Because it contains no preservatives, you must discard the bottle 90 days after first opening to prevent contamination.

How long can I use Murine Refresh & Soothe Eye Mist for?

You can use this product for ongoing dry eye management as long as symptoms require it. However, each bottle should be discarded 90 days after opening regardless of how much product remains. If your symptoms persist or worsen despite regular use, it's worth speaking to a pharmacist or GP to rule out an underlying cause.

What are the alternatives to Murine Refresh & Soothe Eye Mist?

Alternatives include traditional artificial tear drops such as hypromellose 0.3% or carbomer-based gels, which are also available over the counter. Some people prefer eye drops for more targeted application, while others find the mist format easier to use. Your pharmacist can help you choose the right option — you can also explore our eye care range for a broader selection.

Can I use Murine eye mist if I have hay fever-related eye irritation?

Yes — the lubricating and protective properties of this eye mist can help soothe eye irritation caused by environmental allergens such as pollen. However, it does not contain antihistamines, so it won't address the underlying allergic response. For more targeted allergy relief, consider browsing our allergy and hay fever collection alongside this product.

Is Murine Refresh & Soothe Eye Mist the same as an eye mist for dry eyes used after screen time?

Yes — this product is particularly well suited to relieving digital eye strain, which occurs after prolonged screen use and causes the eyes to feel dry, tired, and uncomfortable. The NHS recommends taking regular breaks from screens and using lubricating eye products to manage these symptoms. Murine Refresh & Soothe Eye Mist is a convenient option you can use at your desk without disrupting your workflow.

What happens if I accidentally use too much Murine eye mist?

Using more sprays than recommended is unlikely to cause serious harm, as the ingredients are lubricating agents rather than pharmacologically active drugs. You may experience temporary blurred vision or a watery sensation. If you have any concerns after accidental overuse, contact your pharmacist or NHS 111 for guidance.

What is the latest research on sodium hyaluronate eye drops and dry eye?

Sodium hyaluronate is one of the most widely studied lubricants for dry eye management. Clinical evidence supports its effectiveness in reducing dry eye symptoms and improving tear film stability, and it is recommended in the BNF as a first-line lubricant for dry eye conditions. Research also supports the role of ectoin in protecting ocular surface cells from osmotic and environmental stress, making the combination in this product clinically rational.

How should I store Murine Refresh & Soothe Eye Mist correctly?

Store the bottle below 25°C in a cool, dry place away from direct sunlight and heat. Do not freeze the product. Keep the cap tightly closed when not in use, and write the date of first opening on the bottle so you know when to discard it — the product should be thrown away 90 days after opening.

How Should You Use Murine Refresh & Soothe Eye Mist?

Using this eye mist correctly is simple, but following the right technique ensures you get the most from each application. Always wash your hands before handling the bottle, and remove contact lenses prior to use.

You can also apply the mist to an open eye if you prefer — the fine spray is gentle enough for direct application. Avoid touching the nozzle to your eye or any surface to prevent contamination.

What Is the Correct Dose of Murine Refresh & Soothe Eye Mist?

There is no fixed maximum number of daily applications for this lubricating eye mist — you can use it as often as needed to relieve dryness and discomfort. The table below summarises the recommended dosing by indication and age group.

If you are using other eye preparations alongside this mist, apply Murine first and wait at least 5 minutes before using any other ocular product.

When Is the Best Time to Use Murine Refresh & Soothe Eye Mist?

You can use this eye mist at any point during the day when your eyes feel dry, gritty, or uncomfortable. Many people find it particularly helpful first thing in the morning when eyes can feel stiff after sleep, during long periods of screen use, or in environments with air conditioning or central heating. It's also useful at the end of the day when contact lens wearers often experience peak dryness — just remember to remove lenses before applying.

Keeping the bottle on your desk or in your bag means you can reach for it whenever symptoms arise, making it a practical choice for everyday use.

How Long Can You Use Murine Refresh & Soothe Eye Mist For?

This product can be used for as long as dry eye symptoms require management. There is no recommended maximum duration of use for lubricating eye mists of this type. However, each bottle must be discarded 90 days after first opening, regardless of how much product remains — this is because the preservative-free formula is more susceptible to microbial contamination over time.

If your symptoms have not improved after several weeks of regular use, or if they worsen at any point, you should seek advice from a pharmacist, GP, or optometrist. Persistent dry eye can sometimes indicate an underlying condition that requires further investigation.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Murine Refresh & Soothe Eye Mist?

Most people tolerate this eye mist very well, and side effects are uncommon. Because the product is preservative-free and contains naturally derived lubricating ingredients, the risk of irritation is lower than with some preserved eye drops. That said, as with any ocular preparation, mild reactions can occasionally occur.

  • Brief, mild stinging or burning sensation immediately after application
  • Temporary blurred vision that clears quickly with blinking
  • Watering or increased tear production immediately after use

What Are the Less Common Side Effects of Murine Refresh & Soothe Eye Mist?

Less commonly, some people may notice the following after using this eye mist. These effects are generally mild and short-lived, but you should stop using the product if they persist or cause significant discomfort.

  • Mild redness of the eye or surrounding skin
  • A sensation of something in the eye (foreign body sensation)
  • Eyelid irritation or mild swelling
  • Discomfort if accidentally applied over contact lenses

What Are the Serious Side Effects of Murine Refresh & Soothe Eye Mist?

Serious side effects are rare with this type of product. However, you should stop using the eye mist immediately and seek urgent medical attention if you experience any of the following, as they may indicate an allergic reaction or a more serious eye condition:

  • Significant swelling of the eyelid or face
  • Severe or worsening eye pain
  • Sudden changes in vision
  • Signs of an allergic reaction such as a rash, itching, or difficulty breathing
  • Discharge from the eye or signs of infection

What Should You Do If You Experience Side Effects of Murine Refresh & Soothe Eye Mist?

If you experience mild side effects such as brief stinging or temporary blurred vision, these usually resolve within seconds of blinking and do not require any action. Simply blink several times and allow the mist to settle. If a side effect is persistent, worsening, or causing you concern, stop using the product and speak to your pharmacist or GP. You can also contact NHS 111 for advice if you are unsure whether your symptoms require urgent attention.

Do not attempt to rinse your eye with tap water unless advised to do so by a healthcare professional, as this can sometimes worsen irritation.

Can Murine Refresh & Soothe Eye Mist Interact With Other Medicines?

No significant interactions between this eye mist and systemic medicines have been identified. However, if you use other eye drops or ocular preparations — including prescription eye medications — you should apply Murine Refresh & Soothe Eye Mist first and wait at least 5 minutes before using any other eye product. This prevents dilution of the other medication and ensures both products work as intended. Always inform your pharmacist of all medicines you are currently using, including over-the-counter eye preparations.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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