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Mentholatum Ibuprofen Gel - 50g

Mentholatum Ibuprofen Gel - 50g

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  • ✔️ Targets muscle and joint pain directly at the source
  • ✔️ Contains 5% ibuprofen for effective anti-inflammatory action
  • ✔️ Lower GI side effect risk compared to oral ibuprofen tablets
  • ✔️ Suitable for sports injuries, strains, and sprains
  • ✔️ Compact 50g tube — easy to use at home or on the go

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What Is Ibuprofen Gel and How Does It Relieve Pain?

 

If you're dealing with aching muscles, stiff joints, or a sports injury that's slowing you down, Mentholatum Ibuprofen Gel 50g could be exactly what you need. Ibuprofen gel is a topical non-steroidal anti-inflammatory drug (NSAID) applied directly to the skin over the painful area. Rather than swallowing a tablet, you rub the gel in — and it gets to work locally, right where it hurts. It's a practical, targeted option for everyday pain that many people find easier to use than oral medicines.

Available without a prescription, this 50g tube is well suited to keeping in your medicine cabinet or sports bag. You can browse our full range of pain relief products at Cured Pharmacy if you'd like to compare options before buying.

 

How Does Mentholatum Ibuprofen Gel Work?

 

Ibuprofen belongs to the NSAID class of medicines. When applied topically, it penetrates the skin and underlying tissue to inhibit the enzyme cyclo-oxygenase (COX). This reduces the production of prostaglandins — the chemical messengers responsible for triggering pain and inflammation. The result? Less swelling, less discomfort, and improved mobility in the affected area.

  • Ibuprofen is absorbed through the skin into the local tissue beneath
  • COX-1 and COX-2 enzymes are inhibited, reducing prostaglandin synthesis
  • Inflammation and associated pain signals are dampened at the site
  • Systemic absorption is lower than with oral ibuprofen, reducing the risk of gastrointestinal side effects

 

Who Should Use Mentholatum Ibuprofen Gel?

 

This gel is suitable for adults and young people aged 12 and over who need short-term relief from localised pain and inflammation. It's particularly useful if you prefer not to take tablets, or if you have a sensitive stomach that doesn't tolerate oral NSAIDs well. That said, it's not appropriate for everyone — always read the label carefully.

  • Adults with muscle strains or sprains from sport or everyday activity
  • People with localised joint pain, such as knee or elbow discomfort
  • Those who prefer topical treatment over oral pain relief
  • Individuals managing minor soft tissue injuries

 

How Does Mentholatum Ibuprofen Gel Compare to Ibuprofen Tablets?

 

Feature Mentholatum Ibuprofen Gel 50g Oral Ibuprofen Tablets
Route of administration Topical (applied to skin) Oral (swallowed)
Systemic absorption Low — acts locally High — affects whole body
GI side effect risk Lower Higher
Best suited for Localised muscle/joint pain Widespread pain, fever, headache

 

Is Mentholatum Ibuprofen Gel Suitable for Long-Term Use?

 

Mentholatum Ibuprofen Gel is intended for short-term use only — typically no longer than two weeks. If your pain hasn't improved after this time, it's important to speak to your GP or pharmacist rather than continuing to self-treat. Prolonged use of any NSAID, even topically, warrants professional review. Store the gel below 25°C, away from direct sunlight, and keep it out of reach of children. If you're also managing other conditions alongside pain, our first aid range may have additional products to support your recovery.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Mentholatum Ibuprofen Gel 50g specifications
Treatment category Pain relief / Anti-inflammatory
Active ingredient Ibuprofen 5% w/w
Mechanism of action COX enzyme inhibition — reduces prostaglandin synthesis
Drug class Non-steroidal anti-inflammatory drug (NSAID)
Preparation Topical gel
Route of administration Topical (cutaneous)
Pack size 50g
Suitable for Adults and children aged 12 and over
UK classification General Sale List (GSL) / Pharmacy (P) medicine
Effective for Muscle pain, joint pain, sprains, strains, sports injuries

Specifications of Mentholatum Ibuprofen Gel 50g

 

What Is Mentholatum Ibuprofen Gel and What Is It Used For?

 

Mentholatum Ibuprofen Gel 50g contains ibuprofen 5% w/w as its active ingredient. It is used to relieve pain and reduce inflammation in muscles and joints when applied directly to the skin. Common uses include muscle strains, sprains, sports injuries, and localised joint pain such as that affecting the knee, elbow, or shoulder. It is an over-the-counter medicine available without a prescription for adults and children aged 12 and over.

 

What Do You Need to Know Before Using Mentholatum Ibuprofen Gel?

 

Before using this gel, it's important to check whether it's right for you. Do not use it if any of the following apply:

  • You are allergic to ibuprofen, aspirin, or any other NSAID
  • You have ever had an asthma attack, urticaria, or allergic reaction triggered by aspirin or NSAIDs
  • You are in the third trimester of pregnancy
  • The skin in the area to be treated is broken, damaged, infected, or affected by eczema or dermatitis
  • You are under 12 years of age
  • You have a known sensitivity to any of the excipients in the formulation

Speak to your pharmacist or GP before using this gel if you are pregnant (first or second trimester), breastfeeding, or have kidney, liver, or heart problems. The following drug interactions are worth noting:

  • Oral NSAIDs (e.g. ibuprofen tablets, naproxen) — combined use may increase systemic NSAID exposure
  • Anticoagulants (e.g. warfarin) — small risk of interaction if significant systemic absorption occurs
  • Lithium — topical NSAIDs may theoretically affect lithium levels if absorbed systemically, though risk is low

 

How Should You Use Mentholatum Ibuprofen Gel?

 

Always use this gel exactly as described on the label or as directed by your pharmacist. Do not apply more than the recommended amount, and never use it on large areas of skin or under occlusive dressings unless advised by a healthcare professional.

  1. Wash and dry your hands before applying the gel
  2. Squeeze a small amount (roughly 4–10cm of gel) onto your fingertips
  3. Gently massage the gel into the affected area until fully absorbed
  4. Wash your hands thoroughly after application
  5. Avoid contact with eyes, mouth, nose, or any mucous membranes
  6. Do not cover the treated area with an airtight bandage or dressing
Indication Age Group Dose Frequency
Muscle/joint pain Adults & children 12+ 4–10cm strip of gel Up to 3–4 times daily
Sports injuries Adults & children 12+ 4–10cm strip of gel Up to 3–4 times daily
Children under 12 Under 12 Not recommended

 

What Are the Possible Side Effects of Mentholatum Ibuprofen Gel?

 

Like all medicines, this gel can cause side effects, although not everyone will experience them. Most side effects are localised to the skin at the application site. If you're also exploring other topical treatments, you might find our creams and ointments collection useful for comparison.

Common side effects (may affect up to 1 in 10 people):

  • Mild skin irritation at the application site
  • Redness or warmth of the skin
  • Itching or tingling sensation

Less common side effects (may affect up to 1 in 100 people):

  • Skin rash or dermatitis at the application site
  • Photosensitivity (increased sensitivity to sunlight on treated skin)
  • Localised swelling or blistering — stop use immediately if this occurs

Rarely, topical ibuprofen can cause systemic effects similar to oral NSAIDs, particularly if used over large areas or for prolonged periods. Stop using the gel and seek medical advice if you notice any signs of an allergic reaction, such as difficulty breathing, swelling of the face or throat, or a widespread rash.

 

How Should You Store Mentholatum Ibuprofen Gel?

 

Correct storage helps maintain the gel's effectiveness and safety throughout its shelf life. If you're managing a range of medicines at home, it's worth reviewing our first aid essentials to keep everything organised and accessible.

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Keep the cap tightly closed when not in use
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the tube
  • Do not dispose of medicines via wastewater or household waste — return unused medicines to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Mentholatum Ibuprofen Gel online in the UK?

You can buy Mentholatum Ibuprofen Gel 50g directly from Cured Pharmacy, a UK GPhC-registered online pharmacy. It is available over the counter without a prescription and can be ordered for home delivery. Browse our full pain relief collection for more options alongside this product.

How does ibuprofen gel work on muscle and joint pain?

Ibuprofen gel works by penetrating the skin and inhibiting cyclo-oxygenase (COX) enzymes in the underlying tissue, which reduces the production of prostaglandins — the chemicals that cause pain and inflammation. Because it acts locally at the site of application, it targets the painful area directly. This makes it particularly useful for muscle strains, sprains, and joint discomfort.

How do I apply Mentholatum Ibuprofen Gel step by step?

Wash your hands, then squeeze approximately 4–10cm of gel onto your fingertips and gently massage it into the affected area until absorbed. Wash your hands again after application and avoid touching your eyes, mouth, or any broken skin. Do not cover the treated area with an airtight dressing unless directed by a healthcare professional.

How many times a day can I use ibuprofen gel?

Adults and young people aged 12 and over can apply Mentholatum Ibuprofen Gel up to three to four times daily. Always leave a reasonable gap between applications and do not exceed the frequency stated on the product label. If you find you need to use it more often than this, speak to your pharmacist.

What are the side effects of Mentholatum Ibuprofen Gel?

The most common side effects are localised to the skin and include mild irritation, redness, itching, or a tingling sensation at the application site. Less commonly, a skin rash or increased sensitivity to sunlight may occur. If you experience severe skin reactions, swelling, or any signs of an allergic response, stop using the gel and seek medical advice promptly.

Who should not use Mentholatum Ibuprofen Gel?

This gel is not suitable for children under 12, people with a known allergy to ibuprofen, aspirin, or other NSAIDs, or those with broken, infected, or eczema-affected skin. Women in the third trimester of pregnancy should also avoid it. If you have kidney, liver, or heart conditions, speak to your GP or pharmacist before use.

Can I use ibuprofen gel and ibuprofen tablets at the same time?

Using ibuprofen gel alongside oral ibuprofen tablets is generally not recommended without medical advice, as it may increase your overall NSAID exposure and the risk of side effects. Always tell your pharmacist about all medicines you are currently taking. They can advise whether combining the two is appropriate for your situation.

Is ibuprofen gel safe to use during pregnancy?

Ibuprofen gel should be avoided during the third trimester of pregnancy due to the risk of harm to the unborn baby. Use during the first and second trimesters should only be considered on the advice of a doctor or pharmacist. If you are pregnant and experiencing pain, speak to your GP about safer alternatives.

How long can I use Mentholatum Ibuprofen Gel for?

Mentholatum Ibuprofen Gel is intended for short-term use and should not be applied for more than two weeks without consulting a healthcare professional. If your symptoms have not improved within this time, or if they worsen, see your GP. Prolonged use of any NSAID — even topically — should be reviewed by a professional.

What are the alternatives to Mentholatum Ibuprofen Gel?

Alternatives include other topical NSAIDs such as diclofenac gel, or non-NSAID options like topical ketoprofen or capsaicin cream for certain types of pain. Oral pain relief such as paracetamol or ibuprofen tablets may also be appropriate depending on your symptoms. You can explore a range of options in our creams and ointments collection.

Can I use ibuprofen gel on my back pain?

Yes, topical ibuprofen gel can be used for localised back pain, particularly muscular back pain caused by strain or overexertion. Apply it directly to the painful area and massage in gently. If your back pain is severe, persistent, or accompanied by other symptoms such as numbness or bladder changes, seek medical advice rather than self-treating.

Is Mentholatum Ibuprofen Gel suitable for sports injuries?

Yes, this gel is well suited to minor sports injuries including muscle strains, sprains, and soft tissue inflammation. It can be applied directly to the affected area after activity to help reduce pain and swelling. For more serious injuries, always seek assessment from a healthcare professional before relying solely on topical treatment.

What happens if I accidentally get ibuprofen gel in my eyes?

If the gel comes into contact with your eyes, rinse them immediately and thoroughly with clean, lukewarm water for several minutes. Do not rub your eyes. If irritation persists or your vision is affected, seek medical attention promptly. Always wash your hands after applying the gel to prevent accidental contact.

What is the latest research on topical ibuprofen for pain relief?

Clinical evidence supports the effectiveness of topical ibuprofen for localised musculoskeletal pain, with studies showing it can provide meaningful pain relief with a lower risk of gastrointestinal side effects compared to oral NSAIDs. The NHS recognises topical NSAIDs as a first-line option for certain types of joint and muscle pain. Research continues to explore optimal formulations and patient populations who benefit most.

How should I store Mentholatum Ibuprofen Gel?

Store the gel below 25°C in a cool, dry place away from direct sunlight and heat. Keep the cap tightly closed when not in use and store it out of the reach and sight of children. Do not use the gel after the expiry date printed on the tube, and return any unused medicine to your local pharmacy for safe disposal.

How Should You Use Mentholatum Ibuprofen Gel?

Using this gel correctly makes a real difference to how well it works. Always apply it to clean, dry, intact skin — never to broken, infected, or inflamed skin. Follow these steps each time you use it:

If you accidentally get gel in your eyes or on mucous membranes, rinse thoroughly with clean water and seek advice if irritation continues.

What Is the Correct Dose of Mentholatum Ibuprofen Gel?

The amount of gel you use will depend on the size of the area being treated. As a general guide, a strip of gel measuring 4–10cm is sufficient for most localised areas such as a knee, elbow, or shoulder. Do not apply to large areas of the body simultaneously, and do not use under occlusive dressings unless a healthcare professional has advised you to do so.

When Is the Best Time to Use Mentholatum Ibuprofen Gel?

There is no single fixed time of day that is best for applying this gel — it depends on when your pain is most troublesome. Many people find it helpful to apply it after physical activity, in the morning when stiffness is at its worst, or before bed to ease discomfort overnight. Spacing applications evenly throughout the day (for example, morning, midday, and evening) helps maintain consistent relief. Avoid applying immediately before swimming or bathing, as water will wash the gel away before it has been fully absorbed.

How Long Can You Use Mentholatum Ibuprofen Gel For?

This gel is designed for short-term use only. You should not use it for more than two weeks continuously without speaking to a doctor or pharmacist. Most people find that acute muscle and joint pain improves within a few days of consistent use. If your pain persists beyond two weeks, worsens, or is accompanied by swelling, fever, or other concerning symptoms, seek professional medical advice rather than continuing to self-treat.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Mentholatum Ibuprofen Gel?

Most people who use Mentholatum Ibuprofen Gel tolerate it well, and side effects are generally mild and confined to the skin at the application site. Because the gel is applied topically rather than swallowed, the risk of systemic side effects is considerably lower than with oral ibuprofen.

  • Mild skin irritation or a burning sensation at the application site
  • Redness or warmth of the skin where the gel has been applied
  • Itching or tingling after application
  • Dry skin at the treated area

What Are the Less Common Side Effects of Mentholatum Ibuprofen Gel?

Less frequently, some people may experience more noticeable skin reactions. These are still uncommon but worth being aware of, particularly if you have sensitive skin or a history of skin conditions.

  • Contact dermatitis — a localised rash or inflammation of the skin
  • Photosensitivity — the treated skin may become more sensitive to sunlight
  • Localised swelling or blistering at the application site
  • Skin discolouration in the treated area

If you notice any of these less common reactions, stop using the gel and speak to your pharmacist or GP. Avoid exposing treated skin to direct sunlight or UV lamps while using this product.

What Are the Serious Side Effects of Mentholatum Ibuprofen Gel?

Serious side effects from topical ibuprofen are rare but can occur, particularly if the gel is used over large areas of skin, under occlusive dressings, or for prolonged periods. In these circumstances, more ibuprofen may be absorbed into the bloodstream, potentially causing systemic effects similar to those seen with oral NSAIDs.

Stop using the gel immediately and seek urgent medical attention if you experience any of the following:

  • Difficulty breathing or wheezing — this may indicate a serious allergic reaction
  • Swelling of the face, lips, tongue, or throat (angioedema)
  • A widespread skin rash or hives across the body
  • Severe stomach pain or signs of gastrointestinal upset (rare with topical use)

What Should You Do If You Experience Side Effects?

For mild skin reactions such as redness or itching, simply stop applying the gel to that area and allow the skin to settle. Rinsing the area with cool water may help soothe irritation. If the reaction is more severe or does not resolve within a day or two, contact your pharmacist or GP for advice. Never ignore a worsening skin reaction — it's always better to check.

In the event of a serious allergic reaction, call 999 or go to your nearest A&E immediately. Do not wait to see if symptoms improve on their own.

Can Mentholatum Ibuprofen Gel Interact With Other Medicines?

Although topical ibuprofen has lower systemic absorption than oral forms, interactions are still possible — particularly if you are using other NSAIDs at the same time or taking medicines that affect blood clotting. Tell your pharmacist about all medicines you are currently taking, including over-the-counter products and supplements. Key interactions to be aware of include oral NSAIDs such as ibuprofen or naproxen tablets, anticoagulants such as warfarin, and lithium. Using this gel alongside oral ibuprofen is not generally recommended without professional guidance.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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