Skip to product information
1 of 1

  • Images are for illustration purposes only

Imodium Original 2mg - 12 Capsules

Imodium Original 2mg - 12 Capsules

  • 1. Ozempic®️-equivalent therapy now available for weight management
  • 2. Average weight loss of 17%, with 1 in 3 patients achieving over 20%
  • 3. May help reduce osteoarthritis-related pain
  • 4. Wegovy®️ is not expected to impact the effectiveness of oral contraceptives
  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Relieves acute diarrhoea within one to three hours
  • ✔️ Contains clinically established loperamide hydrochloride 2mg
  • ✔️ Slows bowel movements and reduces fluid loss
  • ✔️ Suitable for adults and young people aged 12 and over
  • ✔️ Convenient 12-capsule pack for home or travel use

Price Checker

Regular price £5.99
Sale price £5.99
Sale Sold out
  • Lowest price guarantee
  • Includes FREE private prescription
View full details

 

What Are Imodium Original Loperamide 2mg Capsules?

 

Diarrhoea can strike at the worst possible moment — whether you're at work, travelling, or simply trying to get through a normal day. Loperamide 2mg capsules, sold under the well-known Imodium Original brand, offer a clinically established way to bring acute diarrhoea under control quickly. Each pack contains 12 capsules, giving you a reliable supply at home or on the go. You can browse our full range of diarrhoea treatments if you'd like to compare options before buying.

Imodium Original is an over-the-counter medicine licensed for use in adults and children aged 12 and over. It contains loperamide hydrochloride 2mg as its active ingredient — a well-studied antidiarrhoeal agent that has been used safely for decades. At just £5.99 for 12 capsules, it's an accessible and practical choice for managing sudden bouts of loose stools.

 

How Does Imodium Original Work to Stop Diarrhoea?

 

Loperamide acts locally within the gut rather than being absorbed into the bloodstream in significant amounts. It targets specific receptors in the intestinal wall to slow things down and restore normal bowel function. Here's how it works step by step:

  • Loperamide binds to opioid receptors (mu-receptors) in the myenteric plexus of the large intestine.
  • This reduces the speed at which the gut muscles contract, slowing the movement of stool through the bowel.
  • It also decreases the secretion of fluid and electrolytes into the gut, reducing the watery nature of loose stools.
  • The result is firmer, less frequent bowel movements — usually within one to three hours of the first dose.

Because loperamide works locally in the gut, it doesn't cause the sedation or central nervous system effects associated with other opioid-type medicines when used at recommended doses.

 

Who Is Imodium Original Suitable For?

 

Imodium Original is designed for adults and young people aged 12 and over who are experiencing acute, short-term diarrhoea. It's particularly useful when diarrhoea is disrupting daily life and you need fast, reliable relief. That said, it isn't right for everyone — so it's worth checking the list below before you take it.

Imodium Original may be suitable if you:

  • Are aged 12 or over and in generally good health
  • Have acute diarrhoea with no blood in your stools and no high fever
  • Need short-term relief while travelling or during a stomach upset
  • Are not currently taking medicines known to interact with loperamide (such as quinidine or ritonavir)

 

How Does Imodium Original Compare to Imodium Instants?

 

Feature Imodium Original 2mg Capsules Imodium Instants 2mg Melts
Active ingredient Loperamide hydrochloride 2mg Loperamide hydrochloride 2mg
Formulation Hard capsule — swallowed with water Orodispersible tablet — dissolves on tongue
Suitable for Adults and children aged 12+ Adults and children aged 12+
Convenience Standard — requires water Higher — no water needed

 

How Should You Store Imodium Original Capsules?

 

Store your loperamide 2mg capsules below 25°C in a dry place, away from direct sunlight. Keep them in their original packaging and out of the reach and sight of children. Do not use the capsules after the expiry date printed on the pack. If you're managing a range of digestive health concerns, you might also find our IBS and cramps collection useful alongside this product.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Imodium Original 2mg Capsules specifications
Treatment category Antidiarrhoeal
Active ingredient Loperamide hydrochloride 2mg
Mechanism of action Opioid receptor agonist — slows intestinal motility and reduces fluid secretion
Effective for Acute diarrhoea
Suitable for Adults and children aged 12 and over
Pack size 12 capsules
Strength 2mg per capsule
UK classification General Sale List (GSL)
Drug class Antidiarrhoeal / Opioid receptor agonist
Preparation Hard capsule
Route of administration Oral

Specifications of Imodium Original 2mg Capsules

 

What Is Imodium Original and What Is It Used For?

 

Imodium Original 2mg capsules are an over-the-counter antidiarrhoeal medicine used to treat acute diarrhoea in adults and young people aged 12 and over. Each capsule contains loperamide hydrochloride 2mg, which works within the gut to slow bowel movements and reduce the loss of fluid and salts. The NHS recognises loperamide as a first-line treatment for short-term diarrhoea in adults. It is not a cure for the underlying cause of diarrhoea — rather, it manages the symptoms while your body recovers.

Diarrhoea is defined as passing three or more loose or watery stools in a 24-hour period. It can be caused by infections, food intolerances, stress, or medicines. Imodium Original helps reduce the frequency and urgency of loose stools so you can carry on with daily life more comfortably.

 

What Do You Need to Know Before Using Imodium Original?

 

Before taking Imodium Original, it's important to check whether it's appropriate for your situation. Do not take these capsules if any of the following apply to you:

  • You are under 12 years of age
  • You have blood or mucus in your stools
  • You have a high temperature (fever) alongside diarrhoea
  • You have been diagnosed with acute ulcerative colitis or pseudomembranous colitis
  • You are allergic to loperamide hydrochloride or any other ingredient in the capsule
  • You have a condition where slowing gut movement could be harmful (e.g. ileus)

Speak to your pharmacist or GP before taking Imodium Original if you are pregnant, breastfeeding, or have liver disease, as loperamide may not be suitable in these circumstances.

The following medicines may interact with loperamide and should be discussed with a healthcare professional before use:

  • Quinidine (used for heart rhythm problems) — may increase loperamide blood levels
  • Ritonavir (an HIV medicine) — may significantly raise loperamide plasma concentrations
  • Itraconazole or ketoconazole (antifungal medicines) — may affect how loperamide is processed
  • Other medicines that slow gut motility

 

How Should You Use Imodium Original Capsules?

 

Always take Imodium Original exactly as directed on the packaging or as advised by your pharmacist. Swallow each capsule whole with a glass of water. Do not chew or open the capsules.

  1. Take 2 capsules (4mg) as your starting dose at the first sign of diarrhoea.
  2. After each subsequent loose stool, take 1 capsule (2mg).
  3. Do not take more than 4 capsules (8mg) in any 24-hour period.
  4. Continue to drink plenty of fluids to replace those lost through diarrhoea.
  5. If diarrhoea has not improved within 48 hours, stop taking the capsules and seek medical advice.
Indication Age Group Starting Dose Subsequent Dose Maximum Daily Dose
Acute diarrhoea Adults and children 12+ 2 capsules (4mg) 1 capsule (2mg) after each loose stool 4 capsules (8mg)
Acute diarrhoea Under 12 Not recommended — seek medical advice

 

What Are the Possible Side Effects of Imodium Original?

 

Like all medicines, Imodium Original can cause side effects, although not everyone experiences them. Most side effects are mild and short-lived. If you're also managing other digestive symptoms, our indigestion collection may offer additional support.

Common side effects (may affect up to 1 in 10 people):

  • Constipation
  • Flatulence (wind)
  • Headache
  • Nausea
  • Abdominal cramps or discomfort

Less common side effects (may affect up to 1 in 100 people):

  • Dizziness or drowsiness
  • Dry mouth
  • Vomiting
  • Skin rash or itching
  • Abdominal bloating

Stop taking Imodium Original and seek immediate medical attention if you develop a severe allergic reaction (swelling of the face, lips, or throat, difficulty breathing, or a widespread rash). Serious cardiac events have been reported with very high doses — always stay within the recommended maximum.

 

How Should You Store Imodium Original Capsules?

 

  • Store below 25°C in a dry place away from direct heat and sunlight.
  • Keep in the original blister packaging until ready to use.
  • Keep out of the sight and reach of children.
  • Do not use after the expiry date printed on the pack.
  • Do not dispose of medicines via wastewater or household waste — return unused capsules to your pharmacist for safe disposal.

If you're travelling and need to manage your health kit, you might also want to explore our travel health range for other essentials.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Imodium Original 2mg capsules online in the UK?

You can buy Imodium Original 2mg capsules directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. No prescription is needed as this is an over-the-counter medicine. Simply add to your basket and choose your preferred delivery option at checkout.

How does loperamide 2mg work in the body?

Loperamide binds to opioid receptors in the gut wall, slowing down the muscular contractions that move stool through the intestine. It also reduces the amount of fluid secreted into the bowel, which is why stools become firmer and less frequent. It works locally in the gut and is not significantly absorbed into the bloodstream at recommended doses.

How do I take Imodium Original capsules step by step?

Start with 2 capsules (4mg) as your initial dose, then take 1 capsule (2mg) after each subsequent loose stool. Do not exceed 4 capsules (8mg) in any 24-hour period. Swallow each capsule whole with a full glass of water and keep drinking fluids throughout to stay hydrated.

How quickly does Imodium Original start working?

Most people notice a reduction in the frequency of loose stools within one to three hours of taking the first dose. Significant improvement is usually seen within 24 hours. If there is no improvement after 48 hours, stop taking the capsules and speak to your GP.

What is the maximum dose of Imodium Original I can take in a day?

The maximum dose for adults and young people aged 12 and over is 4 capsules (8mg) in any 24-hour period. Never exceed this amount, as taking too much loperamide can cause serious heart rhythm problems. If your diarrhoea is not controlled at the maximum dose, seek medical advice promptly.

Who should not take Imodium Original capsules?

Imodium Original is not suitable for children under 12, people with bloody or mucus-containing stools, those with a high fever alongside diarrhoea, or anyone with acute ulcerative colitis. People with liver disease or those taking certain medicines such as quinidine or ritonavir should speak to a pharmacist or GP before use. You can explore our wider diarrhoea treatments collection for alternatives if this product isn't right for you.

Can I take Imodium Original if I am pregnant or breastfeeding?

The safety of loperamide during pregnancy and breastfeeding has not been fully established, so you should speak to your GP or midwife before taking it. In many cases, rehydration with oral rehydration salts is recommended as the first approach during pregnancy. Your healthcare professional can advise on the safest option for your situation.

How long can you take Imodium Original for?

Imodium Original is intended for short-term use only. For acute diarrhoea, do not take it for more than 48 hours without seeking medical advice. If your symptoms persist beyond this point, there may be an underlying cause that needs investigation by a doctor.

What happens if I miss a dose of Imodium Original?

Imodium Original is taken on an as-needed basis rather than at fixed intervals, so there is no scheduled dose to miss. Simply take 1 capsule (2mg) after the next loose stool, up to the daily maximum of 4 capsules. Do not double up doses to compensate.

What are the most common side effects of Imodium Original?

The most commonly reported side effects include constipation, flatulence, nausea, headache, and abdominal cramps. These are generally mild and tend to resolve once you stop taking the capsules. If any side effect feels severe or persistent, contact your pharmacist or GP.

Can Imodium Original interact with other medicines?

Yes — loperamide can interact with quinidine, ritonavir, and certain antifungal medicines such as itraconazole, which may increase loperamide levels in the body. Always tell your pharmacist about any other medicines you are taking before starting Imodium Original. If you're managing pain alongside your symptoms, our pain relief collection may also be helpful.

What are the alternatives to Imodium Original capsules?

Alternatives include Imodium Instants (orodispersible tablets containing the same active ingredient), oral rehydration sachets such as Dioralyte, or other loperamide-containing products. Oral rehydration therapy is particularly important alongside any antidiarrhoeal medicine to replace lost fluids and electrolytes. Your pharmacist can help you choose the most appropriate option.

Is Imodium Original suitable for traveller's diarrhoea?

Yes — Imodium Original is commonly used to manage traveller's diarrhoea in adults and young people aged 12 and over, provided there is no blood in the stools and no high fever. It can help reduce the disruption caused by diarrhoea while travelling. Always carry oral rehydration sachets alongside it to maintain hydration.

What are the latest findings on loperamide safety?

Regulatory bodies including the MHRA have highlighted that taking loperamide at doses much higher than recommended can cause serious cardiac side effects, including abnormal heart rhythms. At the recommended OTC doses, loperamide remains a safe and well-tolerated medicine for short-term diarrhoea. Always follow the dosage instructions on the pack and never exceed the stated maximum.

Can I take Imodium Original alongside sickness and nausea medicines?

In many cases, yes — but it depends on the specific medicines involved. If you're experiencing both diarrhoea and nausea, you may find our sickness and nausea collection useful alongside Imodium Original. Always check with your pharmacist before combining medicines to ensure there are no interactions.

How Should You Use Imodium Original Capsules?

Imodium Original capsules are straightforward to use, but it's important to follow the instructions carefully to get the most benefit and avoid taking more than you need. Always swallow each capsule whole with a full glass of water — do not chew, crush, or open the capsules. Staying well hydrated throughout your illness is just as important as taking the medicine itself.

What Is the Correct Dose of Imodium Original?

The dose depends on your age. Imodium Original is not recommended for children under 12 — a doctor should be consulted for younger children with diarrhoea. For adults and young people aged 12 and over, the dosing schedule below applies.

When Is the Best Time to Use Imodium Original?

Take Imodium Original as soon as diarrhoea begins — there is no fixed time of day. The sooner you take the initial dose, the sooner it can start working to slow bowel movements. If you're heading out or travelling, taking a dose before leaving home (once symptoms have started) can help you manage the day more comfortably.

There is no need to take it with food, though some people find it easier on the stomach to have a small snack alongside it. Avoid alcohol while experiencing diarrhoea, as it can worsen dehydration.

How Long Can You Use Imodium Original For?

Imodium Original is intended for short-term use only. Do not take it for more than 48 hours for acute diarrhoea without speaking to a doctor. If symptoms persist beyond this point, there may be an underlying cause — such as a bacterial infection or inflammatory bowel condition — that requires proper investigation and treatment.

Long-term or regular use of loperamide without medical supervision is not recommended. If you find yourself needing antidiarrhoeal medicine frequently, speak to your GP to identify and address the root cause.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

Customer Reviews

Based on 1 review
100%
(1)
0%
(0)
0%
(0)
0%
(0)
0%
(0)
A
Anonymous

Does exactly that it says

What Are the Most Common Side Effects of Imodium Original?

Most people tolerate Imodium Original well, but like all medicines, it can cause side effects in some individuals. Common side effects are generally mild and tend to resolve once you stop taking the capsules or once your diarrhoea has settled.

  • Constipation
  • Flatulence (wind)
  • Nausea
  • Headache
  • Abdominal cramps or discomfort

What Are the Less Common Side Effects of Imodium Original?

Less common side effects occur in fewer people but are still worth being aware of. If you notice any of the following, consider stopping the medicine and speaking to your pharmacist.

  • Dizziness or drowsiness
  • Dry mouth
  • Vomiting
  • Skin rash or itching
  • Abdominal bloating or distension
  • Indigestion

What Are the Serious Side Effects of Imodium Original?

Serious side effects are rare when Imodium Original is taken at the recommended dose. However, taking loperamide at doses higher than recommended has been associated with serious cardiac events, including QT prolongation and ventricular arrhythmias. This is why it is critical never to exceed the stated maximum of 4 capsules (8mg) per day for OTC use.

Stop taking Imodium Original immediately and seek urgent medical attention if you experience chest pain, an irregular or rapid heartbeat, fainting, or difficulty breathing. A severe allergic reaction — characterised by swelling of the face, lips, tongue, or throat, or a widespread skin rash — also requires emergency medical care.

What Should You Do If You Experience Side Effects?

For mild side effects such as constipation or wind, these usually resolve on their own once the diarrhoea has settled and you stop taking the capsules. Drinking plenty of fluids and eating a light diet can help. If a side effect is bothering you or doesn't improve, speak to your pharmacist — they can advise whether you should continue or switch to an alternative approach.

You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. This helps regulators monitor the safety of medicines in real-world use.

Can Imodium Original Interact With Other Medicines?

Yes — loperamide can interact with certain medicines, which may increase the amount of loperamide in your bloodstream and raise the risk of side effects. Known interactions include quinidine (used for heart conditions), ritonavir (an HIV medicine), and antifungal medicines such as itraconazole or ketoconazole. If you are taking any prescription or over-the-counter medicines, always check with your pharmacist before starting Imodium Original.

Combining loperamide with other medicines that slow gut motility may also increase the risk of constipation or bowel obstruction. Your pharmacist is best placed to review your full medicines list and advise accordingly.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

We’re a safe and
regulated UK service

Registered Pharmacy Badge

Lowest Price Guarantee

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

100% discreet packaging

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

Agent

Need help?
Talk to our friendly experts now

How our service works

Service Setup

Service setup

Discreet Packaging

Discreet packaging

Express Delivery

Express delivery